PDB: 9AXM — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 9AXMC
DFGin BLAminus 1 25.0% 9AXMD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP2K1 MP2K1_HUMAN 9AXMC 2.42 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type1 43 - 376 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXMA 2.42 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 38 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
TKL ARAF ARAF_HUMAN 9AXMD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 300 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf

PDB: 9AXM — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 9AXMC
DFGin BLAminus 1 25.0% 9AXMD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP2K1 MP2K1_HUMAN 9AXMC 2.42 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type1 43 - 376 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXMA 2.42 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 38 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
TKL ARAF ARAF_HUMAN 9AXMD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 300 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens

PDB: 9AXM — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism