PDB: 9AXM — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 9AXMC
DFGin BLAminus 1 25.0% 9AXMD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9AXMC Q02750 43 376 393.0 A1AHE:60401 Type1 Inactive DFGin 6.668 14.1318 BLBplus -150.29, 169.67 59.1, 61.29 -116.51, 166.39 40.92, 86.38 -72.68, 94.97 out-none out 15.3794 Saltbr-none 999.0 HRD-in -102.21, -42.14 67.4, -10.68 none-out-out SNCnoo out-out ActLoopNT-out 9.7501 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -64.72, 121.05 APE9-dihe-na -67.96, 179.71 APE8-dihe-out -110.15, -27.15 APE8-rot-out 56.89 APE67-dihe-out -127.4, 134.54 -138.28, 164.48 APE12-dist-out 17.1619 APE11-dist-out 22.1776 APE10-dist-out 24.2389 APE9-dist-out 13.2396 S218A,S222A None None XRAY 2.42 0.263 0.301 C 310.0 290.0 0 26 26 0 [[68, 361]] 1.0 9axm STE_MAP2K1_HUMAN STE 6.5e-98 333.1 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXMA Q02750 38 382 393.0 A1AHE:60401,ANP:60403 Type1,ATPlike Inactive DFGin 6.2039 13.9992 BLBplus -146.84, 170.95 57.84, 58.3 -113.46, 158.4 47.1, 81.42 -71.93, 78.64 out-out out 15.4263 Saltbr-out 15.5133 HRD-in -80.25, -54.29 71.05, 3.5 out-out-out SNCooo out-out ActLoopNT-out 9.1102 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -58.81, 135.38 APE9-dihe-na -86.44, -174.93 APE8-dihe-out -114.7, -19.48 APE8-rot-out 61.33 APE67-dihe-out -156.42, 133.96 -137.25, 175.14 APE12-dist-out 17.3471 APE11-dist-out 22.1228 APE10-dist-out 24.2234 APE9-dist-out 13.2409 S218A,S222A None None XRAY 2.42 0.263 0.301 A 310.0 301.0 0 26 26 0 [[68, 361]] 1.0 9axm STE_MAP2K1_HUMAN STE 6.5e-98 333.1 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL ARAF ARAF_HUMAN 9AXMD P10398 300 574 606.0 No_ligand No_ligand Inactive DFGin 6.537 14.4563 BLAminus -133.64, -166.34 58.44, 74.82 -99.18, 20.43 290.62, 78.99 -62.21, -22.23 in-in in 9.3021 Saltbr-in 2.6289 HRD-in -62.72, -38.43 67.46, -0.31 in-in-out SNCiio in-out ActLoopNT-in 3.1368 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -179.95 APE8-rot-out 175.83 APE67-dihe-in -65.41, -27.15 -90.86, -15.57 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 Y301D,Y302D None None XRAY 2.42 0.263 0.301 D 280.0 256.0 19 30 16 14 [[310, 569]] 1.0 9axm TKL_ARAF_HUMAN TKL 1.1e-77 267.1 2.0 266.0 265.0 446 447 448 450 452 336 354 358 426 428 427 429.0 491 476 471 470 469 468 467 466 465 383 Serine/threonine-protein kinase A-Raf
TKL ARAF ARAF_HUMAN 9AXMB P10398 302 574 606.0 ANP:60602 ATPlike Inactive DFGin 4.5967 13.3268 BLBplus -134.26, 172.61 61.7, 46.72 -103.54, 150.88 54.31, 89.4 54.71, 36.64 out-out out 11.556 Saltbr-out 10.4941 HRD-in -66.55, -46.59 76.65, -12.19 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -153.94 APE8-dihe-in -77.25, 142.54 APE8-rot-out 182.59 APE67-dihe-in -67.09, -22.55 -72.82, -26.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 5.5235 Y301D,Y302D None None XRAY 2.42 0.263 0.301 B 280.0 254.0 19 30 13 17 [[310, 569]] 1.0 9axm TKL_ARAF_HUMAN TKL 1.1e-77 267.1 2.0 266.0 265.0 446 447 448 450 452 336 354 358 426 428 427 429.0 491 476 471 470 469 468 467 466 465 383 Serine/threonine-protein kinase A-Raf

PDB: 9AXM — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 9AXMC
DFGin BLAminus 1 25.0% 9AXMD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9AXMC Q02750 43 376 393.0 A1AHE:60401 Type1 Inactive DFGin 6.668 14.1318 BLBplus -150.29, 169.67 59.1, 61.29 -116.51, 166.39 40.92, 86.38 -72.68, 94.97 out-none out 15.3794 Saltbr-none 999.0 HRD-in -102.21, -42.14 67.4, -10.68 none-out-out SNCnoo out-out ActLoopNT-out 9.7501 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -64.72, 121.05 APE9-dihe-na -67.96, 179.71 APE8-dihe-out -110.15, -27.15 APE8-rot-out 56.89 APE67-dihe-out -127.4, 134.54 -138.28, 164.48 APE12-dist-out 17.1619 APE11-dist-out 22.1776 APE10-dist-out 24.2389 APE9-dist-out 13.2396 S218A,S222A None None XRAY 2.42 0.263 0.301 C 310.0 290.0 0 26 26 0 [[68, 361]] 1.0 9axm Homo sapiens STE_MAP2K1_HUMAN STE 6.5e-98 333.1 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXMA Q02750 38 382 393.0 A1AHE:60401,ANP:60403 Type1,ATPlike Inactive DFGin 6.2039 13.9992 BLBplus -146.84, 170.95 57.84, 58.3 -113.46, 158.4 47.1, 81.42 -71.93, 78.64 out-out out 15.4263 Saltbr-out 15.5133 HRD-in -80.25, -54.29 71.05, 3.5 out-out-out SNCooo out-out ActLoopNT-out 9.1102 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -58.81, 135.38 APE9-dihe-na -86.44, -174.93 APE8-dihe-out -114.7, -19.48 APE8-rot-out 61.33 APE67-dihe-out -156.42, 133.96 -137.25, 175.14 APE12-dist-out 17.3471 APE11-dist-out 22.1228 APE10-dist-out 24.2234 APE9-dist-out 13.2409 S218A,S222A None None XRAY 2.42 0.263 0.301 A 310.0 301.0 0 26 26 0 [[68, 361]] 1.0 9axm Homo sapiens STE_MAP2K1_HUMAN STE 6.5e-98 333.1 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL ARAF ARAF_HUMAN 9AXMD P10398 300 574 606.0 No_ligand No_ligand Inactive DFGin 6.537 14.4563 BLAminus -133.64, -166.34 58.44, 74.82 -99.18, 20.43 290.62, 78.99 -62.21, -22.23 in-in in 9.3021 Saltbr-in 2.6289 HRD-in -62.72, -38.43 67.46, -0.31 in-in-out SNCiio in-out ActLoopNT-in 3.1368 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -179.95 APE8-rot-out 175.83 APE67-dihe-in -65.41, -27.15 -90.86, -15.57 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 Y301D,Y302D None None XRAY 2.42 0.263 0.301 D 280.0 256.0 19 30 16 14 [[310, 569]] 1.0 9axm Homo sapiens TKL_ARAF_HUMAN TKL 1.1e-77 267.1 2.0 266.0 265.0 446 447 448 450 452 336 354 358 426 428 427 429.0 491 476 471 470 469 468 467 466 465 383 Serine/threonine-protein kinase A-Raf
TKL ARAF ARAF_HUMAN 9AXMB P10398 302 574 606.0 ANP:60602 ATPlike Inactive DFGin 4.5967 13.3268 BLBplus -134.26, 172.61 61.7, 46.72 -103.54, 150.88 54.31, 89.4 54.71, 36.64 out-out out 11.556 Saltbr-out 10.4941 HRD-in -66.55, -46.59 76.65, -12.19 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -153.94 APE8-dihe-in -77.25, 142.54 APE8-rot-out 182.59 APE67-dihe-in -67.09, -22.55 -72.82, -26.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 5.5235 Y301D,Y302D None None XRAY 2.42 0.263 0.301 B 280.0 254.0 19 30 13 17 [[310, 569]] 1.0 9axm Homo sapiens TKL_ARAF_HUMAN TKL 1.1e-77 267.1 2.0 266.0 265.0 446 447 448 450 452 336 354 358 426 428 427 429.0 491 476 471 470 469 468 467 466 465 383 Serine/threonine-protein kinase A-Raf

PDB: 9AXM — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name