CMGC_CDK5 (Cyclin-dependent kinase 5)

Total number of chains: 22
Active chains: 13
Uniprot: CDK5_HUMAN
Kinase Domain Residues: 4 - 286
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 22 100.0% AF-Q00535-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
1H4LA 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 287 0 None None Cyclin-dependent kinase 5
1H4LB 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 287 0 None None Cyclin-dependent kinase 5
AF-Q00535-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 5
AF-Q00535-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 5
7VDSB 3.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 288 0 None None Cyclin-dependent kinase 5
1UNLB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 292 0 None D144N Cyclin-dependent kinase 5
3O0GA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 289 0 None D144N Cyclin-dependent kinase 5
1UNGA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ALH Type1 1 - 292 0 None D144N Cyclin-dependent kinase 5
1UNGB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ALH Type1 2 - 288 0 None D144N Cyclin-dependent kinase 5
1UNHA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 2 - 288 0 None D144N Cyclin-dependent kinase 5
1UNHB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 2 - 288 0 None D144N Cyclin-dependent kinase 5
1UNLA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RRC Type1 1 - 292 0 None D144N Cyclin-dependent kinase 5
3O0GB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3O0 Type1 6 - 288 0 None D144N Cyclin-dependent kinase 5
7VDPA 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 2 - 291 0 None None Cyclin-dependent kinase 5
7VDPB 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 3 - 288 0 None None Cyclin-dependent kinase 5
7VDQA 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 64V Type1 2 - 291 0 None None Cyclin-dependent kinase 5
7VDQB 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 64V Type1 3 - 288 0 None None Cyclin-dependent kinase 5
7VDRA 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 63I Type1 2 - 291 0 None None Cyclin-dependent kinase 5
7VDRB 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 63I Type1 3 - 288 0 None None Cyclin-dependent kinase 5
7VDSA 3.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 61U Type1 2 - 291 0 None None Cyclin-dependent kinase 5
4AU8A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi Z3R Type1 2 - 289 0 None None Cyclin-dependent kinase 5
4AU8B 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi Z3R Type1 2 - 289 0 None None Cyclin-dependent kinase 5

CMGC_CDK5 (Cyclin-dependent kinase 5)

Total number of chains: 22
Active chains: 13
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 22 100.0% AF-Q00535-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDK5_HUMAN 1H4LA 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 287 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 1H4LB 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 287 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN AF-Q00535-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN AF-Q00535-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDSB 3.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 288 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 1UNLB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 292 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 3O0GA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 289 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 1UNGA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ALH Type1 1 - 292 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 1UNGB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ALH Type1 2 - 288 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 1UNHA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 2 - 288 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 1UNHB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 2 - 288 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 1UNLA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RRC Type1 1 - 292 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 3O0GB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3O0 Type1 6 - 288 0 None D144N Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDPA 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 2 - 291 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDPB 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 65L Type1 3 - 288 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDQA 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 64V Type1 2 - 291 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDQB 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 64V Type1 3 - 288 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDRA 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 63I Type1 2 - 291 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDRB 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 63I Type1 3 - 288 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 7VDSA 3.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 61U Type1 2 - 291 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 4AU8A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi Z3R Type1 2 - 289 0 None None Cyclin-dependent kinase 5 Homo sapiens
CDK5_HUMAN 4AU8B 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi Z3R Type1 2 - 289 0 None None Cyclin-dependent kinase 5 Homo sapiens

CMGC_CDK5 (Cyclin-dependent kinase 5)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism