Ligand: J60

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 50.0% 2JAMA
DFGin BLAminus 1 25.0% 2XIKA
DFGinter None 1 25.0% 4NZWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK CAMK1G KCC1G_HUMAN 2JAMA 1.7 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo J60 Type1 18 - 302 0 None None Calcium/calmodulin-dependent protein kinase type 1G
CAMK CAMK1G KCC1G_HUMAN 2JAMB 1.7 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo J60 Type1 16 - 301 0 None None Calcium/calmodulin-dependent protein kinase type 1G
STE STK25 STK25_HUMAN 2XIKA 1.97 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii J60 Type1 3 - 292 0 TPO174 None Serine/threonine-protein kinase 25
STE STK25 STK25_HUMAN 4NZWB 3.583 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnni J60 Type1 11 - 292 0 None D158A Serine/threonine-protein kinase 25

Ligand: J60

Total number of chains: 7
Active chains: 2
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 42.9% 6M12b
DFGin None 2 28.6% 2JAMA
DFGin BLBplus 1 14.3% 3HZTA
DFGinter None 1 14.3% 4NZWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK CAMK1G KCC1G_HUMAN 2JAMA 1.7 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo J60 Type1 18 - 302 0 None None Calcium/calmodulin-dependent protein kinase type 1G Homo sapiens
CAMK CAMK1G KCC1G_HUMAN 2JAMB 1.7 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo J60 Type1 16 - 301 0 None None Calcium/calmodulin-dependent protein kinase type 1G Homo sapiens
STE STK25 STK25_HUMAN 2XIKA 1.97 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii J60 Type1 3 - 292 0 TPO174 None Serine/threonine-protein kinase 25 Homo sapiens
STE STK25 STK25_HUMAN 4NZWB 3.583 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnni J60 Type1 11 - 292 0 None D158A Serine/threonine-protein kinase 25 Homo sapiens
OTHER RNASEL A5H025_PIG 6M12B 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, J60 Allosteric, Type1 24 - 726 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M12A 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa J60, 25L Type1, Allosteric 22 - 727 0 None None Ribonuclease L Sus scrofa
CAMK CDPK3 Q3HNM6_TOXGO 3HZTA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno J60 Type1 73 - 533 0 None None Calcium-dependent protein kinase 1 Toxoplasma gondii

Ligand: J60

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6M12b
DFGin BLBplus 1 33.3% 3HZTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER RNASEL A5H025_PIG 6M12B 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, J60 Allosteric, Type1 24 - 726 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M12A 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa J60, 25L Type1, Allosteric 22 - 727 0 None None Ribonuclease L Sus scrofa
CAMK CDPK3 Q3HNM6_TOXGO 3HZTA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno J60 Type1 73 - 533 0 None None Calcium-dependent protein kinase 1 Toxoplasma gondii