Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 7JXIC | P00533 | 700 | 1007 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 7.177 | 14.411 | BLBminus | -132.91, 172.84 | 59.41, 71.0 | -110.11, -162.74 | 349.91, 78.05 | 63.69, 999.0 | out-out | out | 13.513 | Saltbr-out | 12.49 | HRD-in | -66.45, -56.15 | 77.12, -7.0 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.52 | APE8-dihe-in | -79.96, 70.34 | APE8-rot-na | 30.69 | APE67-dihe-in | -73.05, -5.2 | -53.29, -45.71 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.533 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | C | 331 | 283 | 21 | 0 | 0 | 18 | [[712, 970]] | 1.0 | 7jxi | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKA | P00533 | 700 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.862 | 14.824 | BLBplus | -134.12, 169.24 | 58.43, 39.5 | -93.7, 161.51 | 49.25, 87.25 | 75.0, 16.23 | out-out | out | 13.778 | Saltbr-out | 10.461 | HRD-in | -66.55, -57.53 | 81.35, -6.11 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.816 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 138.68 | APE8-dihe-in | -81.09, 70.58 | APE8-rot-na | 30.58 | APE67-dihe-in | -73.21, -4.24 | -54.1, -46.78 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.489 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | A | 331 | 293 | 15 | 0 | 0 | 15 | [[712, 970]] | 1.0 | 7jxk | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKC | P00533 | 701 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.503 | 14.594 | BLBplus | -134.13, 170.52 | 59.34, 39.88 | -92.58, 159.61 | 51.08, 87.14 | 75.55, 20.71 | out-out | out | 13.608 | Saltbr-out | 11.925 | HRD-in | -66.31, -58.5 | 79.98, -6.68 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.44 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 138.55 | APE8-dihe-in | -81.28, 70.99 | APE8-rot-na | 30.58 | APE67-dihe-in | -73.05, -5.14 | -53.98, -44.81 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.444 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | C | 331 | 292 | 15 | 0 | 0 | 15 | [[712, 970]] | 1.0 | 7jxk | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKE | P00533 | 700 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.893 | 14.488 | BLBplus | -134.7, 170.02 | 59.73, 38.84 | -95.72, 161.23 | 49.85, 87.39 | 75.41, 21.47 | out-out | out | 13.509 | Saltbr-out | 11.783 | HRD-in | -66.69, -59.11 | 80.54, -6.15 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 138.43 | APE8-dihe-in | -79.83, 71.88 | APE8-rot-na | 29.74 | APE67-dihe-in | -73.96, -4.52 | -53.36, -45.18 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.534 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | E | 331 | 287 | 16 | 0 | 0 | 16 | [[712, 970]] | 1.0 | 7jxk | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKF | P00533 | 700 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.872 | 14.387 | BLBplus | -134.77, 169.91 | 59.08, 39.36 | -94.94, 160.87 | 49.89, 87.34 | 75.14, 17.06 | out-out | out | 13.528 | Saltbr-out | 12.787 | HRD-in | -66.88, -58.5 | 80.33, -5.79 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.79 | APE8-dihe-in | -81.39, 71.1 | APE8-rot-na | 29.52 | APE67-dihe-in | -73.84, -5.2 | -54.64, -45.48 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.478 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | F | 331 | 292 | 16 | 0 | 0 | 16 | [[712, 970]] | 1.0 | 7jxk | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4DB | P00533 | 700 | 984 | 1210.0 | 8BS:1101,57N:1102 | Type1,Type3 | Inactive | DFGin | 5.216 | 14.759 | BLBplus | -130.83, 169.9 | 60.42, 43.34 | -92.85, 149.61 | 47.56, 91.66 | 72.77, 15.07 | out-none | out | 13.458 | Saltbr-none | 999.0 | HRD-in | -75.42, -54.52 | 82.84, -20.67 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, 176.11 | APE9-dihe-in | -119.54, 129.26 | APE8-dihe-in | -76.04, 63.14 | APE8-rot-na | 30.86 | APE67-dihe-in | -72.75, -5.66 | -53.62, -40.16 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 14.675 | APE9-dist-out | 8.425 | T790M,V948R | None | None | XRAY | 2.0 | 0.195 | 0.221 | B | 333 | 270 | 15 | 0 | 0 | 15 | [[712, 970]] | 1.0 | 6z4d | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXIA | P00533 | 700 | 1006 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 6.002 | 16.539 | BLBtrans | -128.56, -179.35 | 55.18, 20.34 | -72.14, 105.08 | 161.03, 82.24 | -164.24, -136.24 | out-out | out | 13.357 | Saltbr-out | 11.38 | HRD-in | -66.93, -56.02 | 77.07, -6.66 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.19 | APE8-dihe-in | -80.02, 70.1 | APE8-rot-na | 30.7 | APE67-dihe-in | -73.23, -5.24 | -53.52, -45.86 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.479 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | A | 331 | 290 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 7jxi | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXID | P00533 | 702 | 1006 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 5.407 | 16.257 | BLBtrans | -129.42, 179.04 | 50.18, 64.39 | -110.41, 142.47 | 148.26, 80.05 | 85.73, -1.43 | out-out | out | 13.403 | Saltbr-out | 12.596 | HRD-in | -71.0, -57.45 | 77.99, -6.63 | out-out-none | SNCoon | out-none | ActLoopNT-out | 9.223 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.12 | APE8-dihe-in | -80.19, 70.22 | APE8-rot-na | 30.77 | APE67-dihe-in | -72.81, -5.27 | -53.35, -45.51 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.383 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | D | 331 | 289 | 16 | 0 | 0 | 13 | [[712, 970]] | 1.0 | 7jxi | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4DA | P00533 | 701 | 984 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 5.582 | 16.911 | BLBtrans | -114.92, 175.53 | 65.11, 24.14 | -66.3, 140.38 | 162.98, 75.92 | 74.11, -7.31 | out-out | out | 14.215 | Saltbr-out | 12.826 | HRD-in | -79.35, -52.49 | 82.58, -13.07 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.154 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 121.13 | APE8-dihe-in | -73.43, 66.21 | APE8-rot-na | 29.65 | APE67-dihe-in | -74.75, -4.91 | -55.02, -43.04 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.316 | T790M,V948R | None | None | XRAY | 2.0 | 0.195 | 0.221 | A | 333 | 269 | 15 | 0 | 0 | 13 | [[712, 970]] | 1.0 | 6z4d | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXIB | P00533 | 702 | 1004 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 4.641 | 14.267 | None | -127.65, -24.47 | -127.47, 108.69 | -144.39, 139.56 | 46.55, 108.56 | -178.57, -134.7 | out-out | out | 13.417 | Saltbr-out | 12.201 | HRD-in | -66.29, -55.89 | 76.11, -7.1 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.37 | APE8-dihe-in | -80.39, 70.42 | APE8-rot-na | 30.87 | APE67-dihe-in | -73.29, -5.7 | -53.51, -46.28 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.511 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | B | 331 | 274 | 25 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 7jxi | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 5UGCA | P00533 | 702 | 985 | 1210.0 | 8BS:9001 | Type1 | Inactive | DFGout | 14.396 | 8.262 | BBAminus | -131.19, 172.02 | -138.19, 139.68 | -122.92, 19.28 | 287.71, 102.44 | 122.8, -6.46 | out-out | out | 13.418 | Saltbr-out | 10.829 | HRD-in | -75.41, -48.99 | 67.88, 4.79 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.811 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -68.27, 140.43 | APE9-dihe-in | -121.9, 140.0 | APE8-dihe-in | -80.12, 76.64 | APE8-rot-na | 31.38 | APE67-dihe-in | -74.2, -5.62 | -50.31, -42.01 | APE12-dist-na | 12.007 | APE11-dist-na | 8.905 | APE10-dist-na | 10.23 | APE9-dist-in | 6.881 | T790M,L858R,V948R | None | None | XRAY | 1.58 | 0.201 | 0.223 | A | 329 | 280 | 4 | 0 | 0 | 0 | [[712, 970]] | 1.0 | 5ugc | TYR_EGFR_HUMAN | TYR | 6.4e-87 | 297.2 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 7JXIC | P00533 | 700 | 1007 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 7.177 | 14.411 | BLBminus | -132.91, 172.84 | 59.41, 71.0 | -110.11, -162.74 | 349.91, 78.05 | 63.69, 999.0 | out-out | out | 13.513 | Saltbr-out | 12.49 | HRD-in | -66.45, -56.15 | 77.12, -7.0 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.52 | APE8-dihe-in | -79.96, 70.34 | APE8-rot-na | 30.69 | APE67-dihe-in | -73.05, -5.2 | -53.29, -45.71 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.533 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | C | 331 | 283 | 21 | 0 | 0 | 18 | [[712, 970]] | 1.0 | 7jxi | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKA | P00533 | 700 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.862 | 14.824 | BLBplus | -134.12, 169.24 | 58.43, 39.5 | -93.7, 161.51 | 49.25, 87.25 | 75.0, 16.23 | out-out | out | 13.778 | Saltbr-out | 10.461 | HRD-in | -66.55, -57.53 | 81.35, -6.11 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.816 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 138.68 | APE8-dihe-in | -81.09, 70.58 | APE8-rot-na | 30.58 | APE67-dihe-in | -73.21, -4.24 | -54.1, -46.78 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.489 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | A | 331 | 293 | 15 | 0 | 0 | 15 | [[712, 970]] | 1.0 | 7jxk | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKC | P00533 | 701 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.503 | 14.594 | BLBplus | -134.13, 170.52 | 59.34, 39.88 | -92.58, 159.61 | 51.08, 87.14 | 75.55, 20.71 | out-out | out | 13.608 | Saltbr-out | 11.925 | HRD-in | -66.31, -58.5 | 79.98, -6.68 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.44 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 138.55 | APE8-dihe-in | -81.28, 70.99 | APE8-rot-na | 30.58 | APE67-dihe-in | -73.05, -5.14 | -53.98, -44.81 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.444 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | C | 331 | 292 | 15 | 0 | 0 | 15 | [[712, 970]] | 1.0 | 7jxk | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKE | P00533 | 700 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.893 | 14.488 | BLBplus | -134.7, 170.02 | 59.73, 38.84 | -95.72, 161.23 | 49.85, 87.39 | 75.41, 21.47 | out-out | out | 13.509 | Saltbr-out | 11.783 | HRD-in | -66.69, -59.11 | 80.54, -6.15 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 138.43 | APE8-dihe-in | -79.83, 71.88 | APE8-rot-na | 29.74 | APE67-dihe-in | -73.96, -4.52 | -53.36, -45.18 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.534 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | E | 331 | 287 | 16 | 0 | 0 | 16 | [[712, 970]] | 1.0 | 7jxk | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXKF | P00533 | 700 | 1007 | 1210.0 | 8BS:1101,JBJ:1102 | Type1,Type3 | Inactive | DFGin | 4.872 | 14.387 | BLBplus | -134.77, 169.91 | 59.08, 39.36 | -94.94, 160.87 | 49.89, 87.34 | 75.14, 17.06 | out-out | out | 13.528 | Saltbr-out | 12.787 | HRD-in | -66.88, -58.5 | 80.33, -5.79 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.79 | APE8-dihe-in | -81.39, 71.1 | APE8-rot-na | 29.52 | APE67-dihe-in | -73.84, -5.2 | -54.64, -45.48 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.478 | T790M,V948R | None | None | XRAY | 3.1 | 0.223 | 0.261 | F | 331 | 292 | 16 | 0 | 0 | 16 | [[712, 970]] | 1.0 | 7jxk | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4DB | P00533 | 700 | 984 | 1210.0 | 8BS:1101,57N:1102 | Type1,Type3 | Inactive | DFGin | 5.216 | 14.759 | BLBplus | -130.83, 169.9 | 60.42, 43.34 | -92.85, 149.61 | 47.56, 91.66 | 72.77, 15.07 | out-none | out | 13.458 | Saltbr-none | 999.0 | HRD-in | -75.42, -54.52 | 82.84, -20.67 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, 176.11 | APE9-dihe-in | -119.54, 129.26 | APE8-dihe-in | -76.04, 63.14 | APE8-rot-na | 30.86 | APE67-dihe-in | -72.75, -5.66 | -53.62, -40.16 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 14.675 | APE9-dist-out | 8.425 | T790M,V948R | None | None | XRAY | 2.0 | 0.195 | 0.221 | B | 333 | 270 | 15 | 0 | 0 | 15 | [[712, 970]] | 1.0 | 6z4d | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXIA | P00533 | 700 | 1006 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 6.002 | 16.539 | BLBtrans | -128.56, -179.35 | 55.18, 20.34 | -72.14, 105.08 | 161.03, 82.24 | -164.24, -136.24 | out-out | out | 13.357 | Saltbr-out | 11.38 | HRD-in | -66.93, -56.02 | 77.07, -6.66 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.19 | APE8-dihe-in | -80.02, 70.1 | APE8-rot-na | 30.7 | APE67-dihe-in | -73.23, -5.24 | -53.52, -45.86 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.479 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | A | 331 | 290 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 7jxi | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXID | P00533 | 702 | 1006 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 5.407 | 16.257 | BLBtrans | -129.42, 179.04 | 50.18, 64.39 | -110.41, 142.47 | 148.26, 80.05 | 85.73, -1.43 | out-out | out | 13.403 | Saltbr-out | 12.596 | HRD-in | -71.0, -57.45 | 77.99, -6.63 | out-out-none | SNCoon | out-none | ActLoopNT-out | 9.223 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.12 | APE8-dihe-in | -80.19, 70.22 | APE8-rot-na | 30.77 | APE67-dihe-in | -72.81, -5.27 | -53.35, -45.51 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.383 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | D | 331 | 289 | 16 | 0 | 0 | 13 | [[712, 970]] | 1.0 | 7jxi | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4DA | P00533 | 701 | 984 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 5.582 | 16.911 | BLBtrans | -114.92, 175.53 | 65.11, 24.14 | -66.3, 140.38 | 162.98, 75.92 | 74.11, -7.31 | out-out | out | 14.215 | Saltbr-out | 12.826 | HRD-in | -79.35, -52.49 | 82.58, -13.07 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.154 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 121.13 | APE8-dihe-in | -73.43, 66.21 | APE8-rot-na | 29.65 | APE67-dihe-in | -74.75, -4.91 | -55.02, -43.04 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.316 | T790M,V948R | None | None | XRAY | 2.0 | 0.195 | 0.221 | A | 333 | 269 | 15 | 0 | 0 | 13 | [[712, 970]] | 1.0 | 6z4d | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXIB | P00533 | 702 | 1004 | 1210.0 | 8BS:1101 | Type1 | Inactive | DFGin | 4.641 | 14.267 | None | -127.65, -24.47 | -127.47, 108.69 | -144.39, 139.56 | 46.55, 108.56 | -178.57, -134.7 | out-out | out | 13.417 | Saltbr-out | 12.201 | HRD-in | -66.29, -55.89 | 76.11, -7.1 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 137.37 | APE8-dihe-in | -80.39, 70.42 | APE8-rot-na | 30.87 | APE67-dihe-in | -73.29, -5.7 | -53.51, -46.28 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.511 | T790M,V948R | None | None | XRAY | 3.0 | 0.278 | 0.312 | B | 331 | 274 | 25 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 7jxi | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 5UGCA | P00533 | 702 | 985 | 1210.0 | 8BS:9001 | Type1 | Inactive | DFGout | 14.396 | 8.262 | BBAminus | -131.19, 172.02 | -138.19, 139.68 | -122.92, 19.28 | 287.71, 102.44 | 122.8, -6.46 | out-out | out | 13.418 | Saltbr-out | 10.829 | HRD-in | -75.41, -48.99 | 67.88, 4.79 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.811 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -68.27, 140.43 | APE9-dihe-in | -121.9, 140.0 | APE8-dihe-in | -80.12, 76.64 | APE8-rot-na | 31.38 | APE67-dihe-in | -74.2, -5.62 | -50.31, -42.01 | APE12-dist-na | 12.007 | APE11-dist-na | 8.905 | APE10-dist-na | 10.23 | APE9-dist-in | 6.881 | T790M,L858R,V948R | None | None | XRAY | 1.58 | 0.201 | 0.223 | A | 329 | 280 | 4 | 0 | 0 | 0 | [[712, 970]] | 1.0 | 5ugc | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.4e-87 | 297.2 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|