TYR_DDR1 (Epithelial discoidin domain-containing receptor 1)

Total number of chains: 43
Active chains: 2
Uniprot: DDR1_HUMAN
Kinase Domain Residues: 610 - 907
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 33 76.7% 6FIOA
DFGinter None 5 11.6% 6Y23A
DFGout None 3 7.0% 5SB2A
DFGin BLAminus 2 4.7% AF-Q08345-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q08345-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1
AF-Q08345-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1
6Y23A 2.58 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 574 - 907 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1
6Y23B 2.58 Inactive DFGinter‑None in-out out-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 574 - 910 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1
6Y23C 2.58 Inactive DFGinter‑None in-out out-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 574 - 911 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1
6BRJA 2.231 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 605 - 913 0 None None Epithelial discoidin domain-containing receptor 1
6BSDA 2.606 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
5SAUA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IF Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
5SAVA 1.76 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 909 0 None None Epithelial discoidin domain-containing receptor 1
5SAWA 1.601 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 603 - 907 0 None None Epithelial discoidin domain-containing receptor 1
5SAXA 1.902 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
5SAYA 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 907 0 None None Epithelial discoidin domain-containing receptor 1
5SAYB 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 911 0 None None Epithelial discoidin domain-containing receptor 1
5SAZA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IW Type2 603 - 913 0 None None Epithelial discoidin domain-containing receptor 1
5SB0A 1.97 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IZ Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1
5SB1A 1.53 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1JI Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1
6FEWA 1.44 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1
6FEXA 1.291 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Z Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1
6FILA 1.73 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
6FINA 1.67 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJQ Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1
6FIOA 1.99 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJH Type2 598 - 912 0 None None Epithelial discoidin domain-containing receptor 1
6FIQA 1.79 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai DJW Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
3ZOSB 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
4BKJA 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
4BKJB 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
4CKRA 2.2 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai DI1 Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
6GWRA 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1
6GWRB 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1
6HP9A 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 601 - 909 0 None None Epithelial discoidin domain-containing receptor 1
6HP9B 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 603 - 909 0 None None Epithelial discoidin domain-containing receptor 1
7BCMA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1
7BCMB 2.3 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
7BE6A 1.871 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TJW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1
5BVNA 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
5BVOA 1.98 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VE Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
5FDPA 2.25 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5WR Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
5FDXA 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1
5FDXB 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 605 - 907 0 None None Epithelial discoidin domain-containing receptor 1
3ZOSA 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI, 0LI Type2, Allosteric 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1
7FEHA 1.61 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 3UI Type3 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1
5BVWA 1.94 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
5SB2A 1.6 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 1K2 Type2 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1
5BVKA 2.29 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VC Type3 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1

TYR_DDR1 (Epithelial discoidin domain-containing receptor 1)

Total number of chains: 43
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 33 76.7% 6FIOA
DFGinter None 5 11.6% 6Y23A
DFGout None 3 7.0% 5SB2A
DFGin BLAminus 2 4.7% AF-Q08345-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
DDR1_HUMAN AF-Q08345-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN AF-Q08345-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6Y23A 2.58 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 574 - 907 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6Y23B 2.58 Inactive DFGinter‑None in-out out-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 574 - 910 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6Y23C 2.58 Inactive DFGinter‑None in-out out-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 574 - 911 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6BRJA 2.231 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 605 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6BSDA 2.606 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SAUA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IF Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SAVA 1.76 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SAWA 1.601 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 603 - 907 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SAXA 1.902 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SAYA 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 907 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SAYB 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SAZA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IW Type2 603 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SB0A 1.97 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IZ Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SB1A 1.53 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1JI Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6FEWA 1.44 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6FEXA 1.291 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Z Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6FILA 1.73 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6FINA 1.67 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJQ Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6FIOA 1.99 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJH Type2 598 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6FIQA 1.79 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai DJW Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 3ZOSB 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 4BKJA 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 4BKJB 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 4CKRA 2.2 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai DI1 Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6GWRA 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6GWRB 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6HP9A 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 601 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 6HP9B 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 603 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 7BCMA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 7BCMB 2.3 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 7BE6A 1.871 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TJW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5BVNA 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5BVOA 1.98 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VE Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5FDPA 2.25 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5WR Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5FDXA 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5FDXB 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 605 - 907 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 3ZOSA 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI, 0LI Type2, Allosteric 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 7FEHA 1.61 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 3UI Type3 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5BVWA 1.94 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5SB2A 1.6 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 1K2 Type2 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
DDR1_HUMAN 5BVKA 2.29 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VC Type3 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens

TYR_DDR1 (Epithelial discoidin domain-containing receptor 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism