TYR_DDR1 (Epithelial discoidin domain-containing receptor 1)

Total number of chains: 43
Active chains: 2
Family: TYR
Uniprot: DDR1_HUMAN
Kinase Domain Residues: 610 - 907
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 33 76.7% 6FIOA
DFGinter None 5 11.6% 6Y23A
DFGout None 3 7.0% 5SB2A
DFGin BLAminus 2 4.7% AF-Q08345-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q08345-K1A 602 913 913.0 No_ligand No_ligand Active DFGin 6.776 14.251 BLAminus -135.06, -174.55 56.07, 67.13 -83.23, 9.34 288.88, 95.5 -59.59, -35.2 in-in in 8.306 Saltbr-in 2.737 HRD-in -72.01, -45.8 68.4, -12.55 in-in-in SNCiii in-in ActLoopNT-in 2.867 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.29, 116.83 APE9-dihe-in -129.69, 149.29 APE8-dihe-in -78.52, 77.08 APE8-rot-na 37.11 APE67-dihe-in -70.63, -17.98 -53.54, -33.2 APE12-dist-na 13.882 APE11-dist-na 8.242 APE10-dist-na 10.03 APE9-dist-in 6.189 None None None AF2 -1.0 1.0 1.0 A 312 312 0 0 0 0 [[610, 907]] 1.0 AF-Q08345-K1 TYR_DDR1_HUMAN TYR 1.5e-92 315.6 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
AF-Q08345-K3A 602 913 913.0 No_ligand No_ligand Active DFGin 6.302 14.228 BLAminus -132.1, -173.2 56.14, 63.84 -78.09, 7.68 289.83, 94.44 -56.87, -37.29 in-in in 8.688 Saltbr-in 2.81 HRD-in -76.69, -47.13 69.33, -1.74 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.95, 123.42 APE9-dihe-in -118.26, 146.05 APE8-dihe-in -78.02, 73.53 APE8-rot-na 35.43 APE67-dihe-in -67.28, -19.02 -51.2, -30.77 APE12-dist-na 14.744 APE11-dist-na 9.296 APE10-dist-na 11.48 APE9-dist-in 6.828 None None None AF2 -1.0 1.0 1.0 A 312 312 0 0 0 0 [[610, 907]] 1.0 AF-Q08345-K3 TYR_DDR1_HUMAN TYR 1.5e-92 315.6 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6Y23A 574 907 913.0 No_ligand No_ligand Inactive DFGinter 10.153 7.308 None -140.3, -158.95 -155.89, 34.86 -96.49, -19.82 306.08, 111.29 -54.16, -38.8 in-out in 7.431 Saltbr-out 4.303 HRD-in -69.02, -55.97 80.69, 2.43 out-out-in SNCooi out-in ActLoopNT-out 17.592 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -133.93, 116.48 APE9-dihe-in -127.74, 145.71 APE8-dihe-in -88.51, 68.54 APE8-rot-na 35.64 APE67-dihe-in -68.64, -17.14 -58.48, -33.24 APE12-dist-na 999.0 APE11-dist-na 12.248 APE10-dist-na 7.88 APE9-dist-in 7.176 Y569F,Y586F None None XRAY 2.58 0.228 0.27 A 350 305 27 0 0 3 [[610, 907]] 1.0 6y23 TYR_DDR1_HUMAN TYR 2.2e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6Y23B 574 910 913.0 No_ligand No_ligand Inactive DFGinter 10.177 7.489 None -147.65, -164.17 -143.7, 24.01 -83.51, -17.89 309.63, 115.78 -53.01, -42.7 in-out in 7.401 Saltbr-out 4.538 HRD-in -62.79, -53.56 80.0, -6.1 out-out-none SNCoon out-none ActLoopNT-out 17.396 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 122.54 APE9-dihe-in -139.37, 143.31 APE8-dihe-in -88.22, 70.91 APE8-rot-na 34.24 APE67-dihe-in -65.16, -14.5 -56.89, -35.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 7.79 APE9-dist-in 7.245 Y569F,Y586F None None XRAY 2.58 0.228 0.27 B 350 301 30 0 0 5 [[610, 907]] 1.0 6y23 TYR_DDR1_HUMAN TYR 2.2e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6Y23C 574 911 913.0 No_ligand No_ligand Inactive DFGinter 10.326 7.424 None -131.36, -161.95 -146.38, 29.72 -92.15, -18.74 310.61, 115.72 -49.18, -37.85 in-out in 7.603 Saltbr-out 5.078 HRD-in -65.34, -54.8 81.25, 2.61 out-out-none SNCoon out-none ActLoopNT-out 17.518 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 131.97 APE9-dihe-in -138.28, 145.82 APE8-dihe-in -85.36, 72.32 APE8-rot-na 34.45 APE67-dihe-in -71.14, -17.59 -62.42, -29.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 8.108 APE9-dist-in 7.111 Y569F,Y586F None None XRAY 2.58 0.228 0.27 C 350 305 33 0 0 5 [[610, 907]] 1.0 6y23 TYR_DDR1_HUMAN TYR 2.2e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6BRJA 605 913 913.0 VX6:60901 Type1 Inactive DFGinter 9.842 6.444 None -75.98, 130.59 -108.73, 22.4 -131.46, 172.46 67.8, 95.77 -125.27, 159.76 in-in in 8.607 Saltbr-in 2.475 HRD-in -69.59, -46.48 76.5, -9.43 in-out-in SNCioi out-in ActLoopNT-out 18.162 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.43, 114.86 APE9-dihe-in -119.04, 131.61 APE8-dihe-in -82.29, 70.03 APE8-rot-na 39.02 APE67-dihe-in -70.78, -15.74 -55.16, -32.48 APE12-dist-na 18.237 APE11-dist-na 14.849 APE10-dist-na 11.084 APE9-dist-in 7.365 None None None XRAY 2.231 0.189 0.223 A 351 274 35 0 0 0 [[610, 907]] 1.0 6brj TYR_DDR1_HUMAN TYR 2.3e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6BSDA 604 912 913.0 1N1:60901 Type1 Inactive DFGinter 9.948 9.844 None -87.87, 155.34 -64.16, -24.42 174.69, 170.82 68.3, 89.44 55.93, 999.0 in-in in 8.37 Saltbr-in 2.735 HRD-in -61.68, -56.93 83.98, -4.33 in-out-in SNCioi out-in ActLoopNT-out 19.848 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.74, 115.57 APE9-dihe-in -116.16, 127.65 APE8-dihe-in -81.76, 68.68 APE8-rot-na 34.21 APE67-dihe-in -66.93, -20.25 -61.43, -30.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.146 None None None XRAY 2.606 0.186 0.255 A 351 278 31 0 0 2 [[610, 907]] 1.0 6bsd TYR_DDR1_HUMAN TYR 2.3e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SAUA 604 912 913.0 1IF:61000 Type2 Inactive DFGout 12.628 9.672 BBAminus -137.39, -170.54 -153.95, 108.1 -100.48, 5.9 289.81, 101.12 83.39, -174.73 in-in in 8.355 Saltbr-in 2.869 HRD-in -71.66, -48.67 82.15, -10.52 in-out-in SNCioi out-in ActLoopNT-out 18.139 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.56, 139.94 APE9-dihe-in -129.66, 123.98 APE8-dihe-in -80.56, 70.77 APE8-rot-na 35.49 APE67-dihe-in -73.85, -9.33 -63.13, -31.85 APE12-dist-na 13.331 APE11-dist-na 10.312 APE10-dist-na 5.884 APE9-dist-in 7.555 None None None XRAY 1.8 0.201 0.231 A 321 287 16 0 0 0 [[610, 907]] 1.0 5sau TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SAVA 602 909 913.0 1IJ:61001 Type2 Inactive DFGout 12.249 9.892 BBAminus -137.58, -169.64 -150.62, 110.81 -103.5, 11.77 291.8, 111.79 80.59, -174.76 in-in in 8.531 Saltbr-in 2.847 HRD-in -72.55, -49.58 80.09, -14.29 in-out-in SNCioi out-in ActLoopNT-out 18.108 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.25, 135.7 APE9-dihe-in -126.66, 126.5 APE8-dihe-in -76.9, 69.2 APE8-rot-na 29.65 APE67-dihe-in -68.15, -12.71 -57.84, -36.12 APE12-dist-na 13.471 APE11-dist-na 10.502 APE10-dist-na 6.037 APE9-dist-in 7.293 None None None XRAY 1.76 0.195 0.235 A 321 291 11 0 0 0 [[610, 907]] 1.0 5sav TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SAWA 603 907 913.0 1IM:61001 Type2 Inactive DFGout 12.493 9.439 BBAminus -136.32, -167.56 -154.42, 105.26 -96.79, 11.36 288.89, 101.22 78.08, -173.73 in-in in 8.104 Saltbr-in 2.688 HRD-in -72.41, -49.17 82.35, -13.45 in-out-in SNCioi out-in ActLoopNT-out 18.003 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.99, 135.55 APE9-dihe-in -127.2, 125.08 APE8-dihe-in -79.96, 65.74 APE8-rot-na 30.31 APE67-dihe-in -73.33, -9.46 -58.7, -30.17 APE12-dist-na 13.306 APE11-dist-na 10.135 APE10-dist-na 5.737 APE9-dist-in 7.441 None None None XRAY 1.601 0.201 0.226 A 321 291 8 0 0 0 [[610, 907]] 1.0 5saw TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SAXA 601 913 913.0 1IM:61009 Type2 Inactive DFGout 12.785 9.652 BBAminus -136.63, -167.06 -151.99, 103.38 -94.74, 11.71 289.58, 96.46 77.91, -172.64 in-in in 8.233 Saltbr-in 2.686 HRD-in -70.12, -47.49 78.55, -13.59 in-out-in SNCioi out-in ActLoopNT-out 18.058 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.48, 134.35 APE9-dihe-in -127.3, 128.21 APE8-dihe-in -84.18, 72.54 APE8-rot-na 32.87 APE67-dihe-in -73.3, -15.34 -61.77, -28.17 APE12-dist-na 13.332 APE11-dist-na 10.305 APE10-dist-na 5.824 APE9-dist-in 7.44 None None None XRAY 1.902 0.212 0.254 A 321 302 5 0 0 0 [[610, 907]] 1.0 5sax TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SAYA 602 907 913.0 1IJ:61009 Type2 Inactive DFGout 13.11 10.338 BBAminus -139.08, -171.59 -152.18, 105.65 -84.47, 2.41 293.81, 95.27 76.78, -161.44 in-in in 8.613 Saltbr-in 2.856 HRD-in -76.95, -56.11 85.16, -6.58 in-out-in SNCioi out-in ActLoopNT-out 18.086 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.13, 129.59 APE9-dihe-in -128.34, 133.74 APE8-dihe-in -84.79, 68.27 APE8-rot-na 30.95 APE67-dihe-in -71.25, -15.06 -62.46, -28.48 APE12-dist-na 13.985 APE11-dist-na 10.957 APE10-dist-na 6.246 APE9-dist-in 7.324 None None None XRAY 2.19 0.206 0.277 A 321 290 10 0 0 0 [[610, 907]] 1.0 5say TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SAYB 602 911 913.0 1IJ:61008 Type2 Inactive DFGout 12.9 9.62 BBAminus -142.01, -168.91 -152.05, 105.38 -85.39, 0.61 294.66, 96.94 74.6, -161.8 in-in in 8.465 Saltbr-in 2.871 HRD-in -72.03, -52.9 85.69, -8.23 in-out-in SNCioi out-in ActLoopNT-out 18.068 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.08, 123.36 APE9-dihe-in -135.38, 149.1 APE8-dihe-in -77.36, 69.77 APE8-rot-na 31.97 APE67-dihe-in -71.49, -13.73 -62.32, -28.79 APE12-dist-na 14.317 APE11-dist-na 10.434 APE10-dist-na 6.946 APE9-dist-in 7.157 None None None XRAY 2.19 0.206 0.277 B 321 288 16 0 0 0 [[610, 907]] 1.0 5say TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SAZA 603 913 913.0 1IW:61001 Type2 Inactive DFGout 13.69 10.143 BBAminus -137.95, -165.09 -152.44, 116.71 -99.61, 2.45 287.9, 84.51 75.93, -173.07 in-in in 8.329 Saltbr-in 2.833 HRD-in -71.16, -46.01 79.1, -11.15 in-out-in SNCioi out-in ActLoopNT-out 18.097 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.41, 142.17 APE9-dihe-in -131.47, 123.66 APE8-dihe-in -78.39, 69.53 APE8-rot-na 32.74 APE67-dihe-in -72.73, -11.69 -61.24, -31.8 APE12-dist-na 13.182 APE11-dist-na 10.338 APE10-dist-na 5.805 APE9-dist-in 7.413 None None None XRAY 1.8 0.189 0.224 A 321 290 15 0 0 0 [[610, 907]] 1.0 5saz TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SB0A 604 913 913.0 1IZ:61002 Type2 Inactive DFGout 14.205 11.415 BBAminus -134.1, -167.44 -149.3, 103.34 -77.41, -7.41 286.62, 82.49 82.96, -174.18 in-in in 7.949 Saltbr-in 2.485 HRD-in -69.43, -51.57 85.83, -12.36 in-out-in SNCioi out-in ActLoopNT-out 18.072 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.15, 129.55 APE9-dihe-in -121.03, 123.84 APE8-dihe-in -76.55, 70.49 APE8-rot-na 28.9 APE67-dihe-in -76.04, -15.35 -65.09, -25.8 APE12-dist-na 13.681 APE11-dist-na 10.691 APE10-dist-na 6.122 APE9-dist-in 7.406 None None None XRAY 1.97 0.21 0.256 A 321 284 20 0 0 0 [[610, 907]] 1.0 5sb0 TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SB1A 604 913 913.0 1JI:61001 Type2 Inactive DFGout 12.791 10.273 BBAminus -136.97, -163.16 -159.21, 109.76 -101.99, 10.87 293.72, 105.65 82.9, -171.77 in-in in 7.861 Saltbr-in 2.936 HRD-in -69.06, -48.99 77.38, -14.74 in-out-in SNCioi out-in ActLoopNT-out 18.198 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.56, 137.83 APE9-dihe-in -127.95, 125.11 APE8-dihe-in -81.37, 69.62 APE8-rot-na 31.59 APE67-dihe-in -73.44, -13.11 -59.21, -30.91 APE12-dist-na 13.149 APE11-dist-na 10.252 APE10-dist-na 5.706 APE9-dist-in 7.394 None None None XRAY 1.53 0.19 0.214 A 321 284 20 0 0 0 [[610, 907]] 1.0 5sb1 TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6FEWA 603 911 913.0 D6W:1001 Type2 Inactive DFGout 14.639 11.11 BBAminus -123.11, -164.13 -159.89, 87.13 -66.29, -19.31 278.92, 81.95 89.37, -178.21 in-in in 8.229 Saltbr-in 2.638 HRD-in -71.95, -50.33 82.89, -15.2 in-out-in SNCioi out-in ActLoopNT-out 18.323 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.78, 132.51 APE9-dihe-in -128.37, 122.79 APE8-dihe-in -77.16, 68.85 APE8-rot-na 31.54 APE67-dihe-in -72.02, -12.2 -55.39, -33.21 APE12-dist-na 13.445 APE11-dist-na 10.428 APE10-dist-na 5.901 APE9-dist-in 7.391 None None None XRAY 1.44 0.218 0.241 A 321 291 12 0 0 0 [[610, 907]] 1.0 6few TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6FEXA 602 908 913.0 D6Z:1001 Type2 Inactive DFGout 15.369 10.952 BBAminus -128.49, -167.33 -156.07, 92.0 -71.27, -9.26 285.23, 81.96 80.6, -168.82 in-in in 8.315 Saltbr-in 2.793 HRD-in -70.39, -48.84 82.04, -14.46 in-out-in SNCioi out-in ActLoopNT-out 18.284 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.0, 135.5 APE9-dihe-in -130.56, 128.86 APE8-dihe-in -81.39, 69.61 APE8-rot-na 31.4 APE67-dihe-in -70.03, -14.92 -58.59, -34.04 APE12-dist-na 13.49 APE11-dist-na 10.369 APE10-dist-na 5.964 APE9-dist-in 7.383 None None None XRAY 1.291 0.139 0.174 A 321 289 12 0 0 0 [[610, 907]] 1.0 6fex TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6FILA 604 912 913.0 D6W:61001 Type2 Inactive DFGout 14.441 11.42 BBAminus -114.42, -165.45 -157.03, 86.17 -70.37, -21.94 279.41, 75.3 87.75, -166.46 in-in in 8.01 Saltbr-in 2.679 HRD-in -76.68, -51.8 78.33, -9.55 in-out-in SNCioi out-in ActLoopNT-out 18.428 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.44, 131.81 APE9-dihe-in -123.24, 125.33 APE8-dihe-in -80.01, 68.23 APE8-rot-na 31.21 APE67-dihe-in -71.92, -14.88 -58.1, -31.6 APE12-dist-na 13.401 APE11-dist-na 10.53 APE10-dist-na 6.031 APE9-dist-in 7.265 None None None XRAY 1.73 0.195 0.245 A 321 287 16 0 0 0 [[610, 907]] 1.0 6fil TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6FINA 603 911 913.0 DJQ:1009 Type2 Inactive DFGout 14.863 11.317 BBAminus -129.33, -165.3 -156.6, 92.58 -69.92, -11.44 280.96, 78.02 83.02, -169.31 in-in in 8.294 Saltbr-in 2.765 HRD-in -73.9, -50.38 81.4, -14.94 in-out-in SNCioi out-in ActLoopNT-out 18.495 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.7, 130.0 APE9-dihe-in -127.24, 126.8 APE8-dihe-in -81.19, 70.61 APE8-rot-na 30.53 APE67-dihe-in -74.43, -13.11 -58.96, -28.14 APE12-dist-na 13.715 APE11-dist-na 10.613 APE10-dist-na 6.156 APE9-dist-in 7.388 None None None XRAY 1.67 0.2 0.228 A 321 294 9 0 0 0 [[610, 907]] 1.0 6fin TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6FIOA 598 912 913.0 DJH:61001 Type2 Inactive DFGout 15.177 11.002 BBAminus -127.61, -164.73 -159.21, 87.63 -74.98, -16.13 283.57, 78.17 77.22, -166.77 in-in in 8.573 Saltbr-in 3.003 HRD-in -72.35, -48.97 77.34, -11.82 in-out-in SNCioi out-in ActLoopNT-out 18.741 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.31, 116.38 APE9-dihe-in -134.04, 158.77 APE8-dihe-in -82.95, 69.6 APE8-rot-na 34.53 APE67-dihe-in -69.65, -14.77 -56.14, -33.27 APE12-dist-na 15.393 APE11-dist-na 11.087 APE10-dist-na 7.959 APE9-dist-in 7.39 None None None XRAY 1.99 0.217 0.277 A 321 307 2 0 0 0 [[610, 907]] 1.0 6fio TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6FIQA 601 913 913.0 DJW:61001 Type2 Inactive DFGout 15.147 11.659 BBAminus -129.66, -164.81 -158.71, 85.69 -65.74, -18.84 287.76, 69.48 91.48, -171.72 in-in in 8.191 Saltbr-in 2.905 HRD-in -74.98, -49.59 81.33, -13.91 in-out-out SNCioo out-out ActLoopNT-out 18.338 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -135.13, -40.38 APE9-dihe-in -138.98, 126.92 APE8-dihe-in -80.25, 71.05 APE8-rot-na 32.35 APE67-dihe-in -73.93, -12.67 -61.47, -27.84 APE12-dist-na 8.863 APE11-dist-na 4.817 APE10-dist-na 8.84 APE9-dist-in 7.348 None None None XRAY 1.79 0.201 0.238 A 321 293 14 0 0 0 [[610, 907]] 1.0 6fiq TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
3ZOSB 601 913 913.0 0LI:61000 Type2 Inactive DFGout 13.646 9.63 BBAminus -143.84, 178.94 -153.3, 114.42 -82.71, -15.18 287.49, 108.73 52.14, -127.46 in-in in 7.96 Saltbr-in 2.883 HRD-in -60.43, -59.89 83.25, -8.8 in-out-in SNCioi out-in ActLoopNT-out 17.4 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.91, 133.24 APE9-dihe-in -130.81, 142.32 APE8-dihe-in -80.63, 68.61 APE8-rot-na 30.08 APE67-dihe-in -67.12, -16.99 -59.3, -31.33 APE12-dist-na 11.719 APE11-dist-na 12.939 APE10-dist-na 10.223 APE9-dist-in 7.924 None None None XRAY 1.92 0.208 0.234 B 315 301 12 0 0 0 [[610, 907]] 1.0 3zos TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
4BKJA 601 913 913.0 STI:61000 Type2 Inactive DFGout 13.041 10.869 BBAminus -135.57, -177.41 -150.26, 104.38 -97.26, -19.55 309.91, 132.36 76.19, -179.07 in-in in 8.056 Saltbr-in 2.781 HRD-in -73.25, -56.55 82.61, -12.77 in-out-in SNCioi out-in ActLoopNT-out 18.428 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.84, 113.6 APE9-dihe-in -132.17, 138.55 APE8-dihe-in -81.73, 66.81 APE8-rot-na 30.65 APE67-dihe-in -70.94, -16.71 -56.41, -32.35 APE12-dist-na 999.0 APE11-dist-na 10.43 APE10-dist-na 6.399 APE9-dist-in 7.253 None None None XRAY 1.7 0.157 0.176 A 315 294 19 0 0 4 [[610, 907]] 1.0 4bkj TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
4BKJB 601 913 913.0 STI:61000 Type2 Inactive DFGout 12.942 10.696 BBAminus -134.88, -177.2 -150.26, 104.51 -98.15, -18.24 308.85, 133.85 76.2, -180.0 in-in in 8.078 Saltbr-in 2.781 HRD-in -71.4, -58.01 82.61, -12.4 in-out-in SNCioi out-in ActLoopNT-out 18.43 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.57, 113.98 APE9-dihe-in -133.47, 139.44 APE8-dihe-in -81.51, 65.72 APE8-rot-na 30.98 APE67-dihe-in -69.17, -18.25 -55.39, -33.59 APE12-dist-na 999.0 APE11-dist-na 10.754 APE10-dist-na 6.412 APE9-dist-in 7.213 None None None XRAY 1.7 0.157 0.176 B 315 296 17 0 0 4 [[610, 907]] 1.0 4bkj TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
4CKRA 601 913 913.0 DI1:61000 Type2 Inactive DFGout 13.862 11.486 BBAminus -138.41, 172.1 -152.04, 104.0 -83.41, -39.47 307.21, 120.94 70.34, 17.44 in-in in 8.355 Saltbr-in 2.772 HRD-in -71.2, -61.64 87.29, -10.58 in-out-none SNCion out-none ActLoopNT-out 18.85 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 114.24 APE9-dihe-in -144.37, 137.98 APE8-dihe-in -80.98, 66.37 APE8-rot-na 31.95 APE67-dihe-in -71.92, -18.62 -58.18, -30.83 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.291 APE9-dist-in 7.341 None None None XRAY 2.2 0.201 0.247 A 315 294 19 0 0 4 [[610, 907]] 1.0 4ckr TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6GWRA 601 912 913.0 FEW:61001 Type2 Inactive DFGout 12.8 10.684 BBAminus -134.05, -169.98 -156.8, 106.42 -94.1, 5.66 291.49, 91.7 63.63, -138.67 in-in in 8.986 Saltbr-in 3.053 HRD-in -67.39, -50.22 80.83, -8.55 in-out-in SNCioi out-in ActLoopNT-out 18.628 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -127.27, 154.82 APE9-dihe-in -127.56, 142.54 APE8-dihe-in -85.13, 70.94 APE8-rot-na 33.79 APE67-dihe-in -68.94, -16.33 -59.49, -34.74 APE12-dist-na 9.487 APE11-dist-na 10.655 APE10-dist-na 7.462 APE9-dist-in 7.06 None None None XRAY 2.07 0.202 0.237 A 315 299 13 0 0 0 [[610, 907]] 1.0 6gwr TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6GWRB 602 908 913.0 FEW:61001 Type2 Inactive DFGout 13.011 10.839 BBAminus -135.63, -168.81 -156.8, 100.71 -86.26, 0.96 289.39, 87.09 64.13, -147.41 in-in in 8.594 Saltbr-in 2.936 HRD-in -66.48, -54.41 81.91, -7.37 in-out-in SNCioi out-in ActLoopNT-out 18.469 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -127.74, 153.56 APE9-dihe-in -126.55, 140.43 APE8-dihe-in -85.27, 72.54 APE8-rot-na 32.6 APE67-dihe-in -67.25, -20.33 -64.19, -32.01 APE12-dist-na 9.364 APE11-dist-na 10.87 APE10-dist-na 7.365 APE9-dist-in 6.94 None None None XRAY 2.07 0.202 0.237 B 315 285 22 0 0 0 [[610, 907]] 1.0 6gwr TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6HP9A 601 909 913.0 GKB:61001 Type2 Inactive DFGout 13.913 10.926 BBAminus -145.6, -172.43 -152.86, 103.11 -77.98, 3.78 281.96, 79.76 68.1, -156.94 in-in in 8.49 Saltbr-in 2.724 HRD-in -65.95, -51.98 77.73, -3.58 in-out-in SNCioi out-in ActLoopNT-out 18.268 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -129.05, 129.39 APE9-dihe-in -127.0, 142.65 APE8-dihe-in -84.02, 69.07 APE8-rot-na 35.45 APE67-dihe-in -67.82, -15.87 -61.84, -33.19 APE12-dist-na 13.79 APE11-dist-na 10.502 APE10-dist-na 6.772 APE9-dist-in 7.205 None None None XRAY 1.96 0.207 0.251 A 315 295 14 0 0 0 [[610, 907]] 1.0 6hp9 TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
6HP9B 603 909 913.0 GKB:61001 Type2 Inactive DFGout 13.937 11.029 BBAminus -138.11, -164.71 -161.75, 101.28 -81.09, 0.81 285.57, 77.73 64.83, 177.38 in-in in 8.384 Saltbr-in 2.872 HRD-in -72.07, -47.03 76.05, -7.83 in-out-in SNCioi out-in ActLoopNT-out 18.187 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.8, 132.01 APE9-dihe-in -133.29, 124.1 APE8-dihe-in -79.54, 70.21 APE8-rot-na 34.04 APE67-dihe-in -72.05, -14.89 -58.92, -31.44 APE12-dist-na 14.023 APE11-dist-na 10.867 APE10-dist-na 6.428 APE9-dist-in 7.303 None None None XRAY 1.96 0.207 0.251 B 315 281 26 0 0 0 [[610, 907]] 1.0 6hp9 TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
7BCMA 604 909 913.0 TBK:1001 Type2 Inactive DFGout 13.008 10.093 BBAminus -144.68, -175.9 -143.48, 102.2 -83.62, 3.62 287.6, 81.94 81.32, -168.03 in-in in 8.656 Saltbr-in 3.009 HRD-in -65.71, -55.98 87.34, -19.67 in-out-in SNCioi out-in ActLoopNT-out 18.307 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.26, 137.51 APE9-dihe-in -123.82, 128.63 APE8-dihe-in -86.21, 69.22 APE8-rot-na 27.2 APE67-dihe-in -71.43, -12.52 -62.93, -34.22 APE12-dist-na 13.45 APE11-dist-na 10.503 APE10-dist-na 6.276 APE9-dist-in 7.552 None None None XRAY 2.3 0.246 0.308 A 315 273 33 0 0 0 [[610, 907]] 1.0 7bcm TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
7BCMB 604 911 913.0 TBK:1001 Type2 Inactive DFGout 12.873 10.003 BBAminus -131.16, -172.17 -135.77, 109.56 -94.04, -4.34 282.79, 103.01 90.67, -179.36 in-out in 8.369 Saltbr-out 3.617 HRD-in -62.88, -55.49 80.94, -21.01 out-out-in SNCooi out-in ActLoopNT-out 18.345 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.26, 139.25 APE9-dihe-in -129.42, 124.32 APE8-dihe-in -81.31, 68.14 APE8-rot-na 36.31 APE67-dihe-in -65.99, -20.67 -66.61, -29.37 APE12-dist-na 13.249 APE11-dist-na 10.653 APE10-dist-na 5.986 APE9-dist-in 7.524 None None None XRAY 2.3 0.246 0.308 B 315 266 42 0 0 0 [[610, 907]] 1.0 7bcm TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
7BE6A 601 912 913.0 TJW:61009 Type2 Inactive DFGout 13.274 10.693 BBAminus -133.78, -166.84 -149.99, 107.57 -92.55, -8.19 288.48, 90.78 60.12, -147.46 in-in in 8.551 Saltbr-in 2.9 HRD-in -70.89, -50.95 79.48, -10.8 in-out-in SNCioi out-in ActLoopNT-out 19.026 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -130.64, 162.67 APE9-dihe-in -137.45, 131.08 APE8-dihe-in -82.5, 71.83 APE8-rot-na 34.81 APE67-dihe-in -72.32, -17.47 -59.41, -30.72 APE12-dist-na 10.476 APE11-dist-na 11.104 APE10-dist-na 7.021 APE9-dist-in 7.285 None None None XRAY 1.871 0.189 0.23 A 315 301 11 0 0 0 [[610, 907]] 1.0 7be6 TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5BVNA 604 911 913.0 4VD:1002 Type2 Inactive DFGout 12.52 10.864 BBAminus -133.48, -169.53 -151.91, 105.04 -95.23, 10.51 304.6, 110.5 72.08, -162.27 in-in in 8.622 Saltbr-in 2.79 HRD-in -66.14, -48.88 77.95, -15.06 in-out-in SNCioi out-in ActLoopNT-out 18.242 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.29, 133.25 APE9-dihe-in -125.22, 110.99 APE8-dihe-in -73.41, 62.73 APE8-rot-na 28.5 APE67-dihe-in -72.96, -4.61 -50.16, -37.38 APE12-dist-na 13.084 APE11-dist-na 10.346 APE10-dist-na 5.549 APE9-dist-in 7.446 None None None XRAY 2.21 0.256 0.328 A 324 278 30 0 0 0 [[610, 907]] 1.0 5bvn TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5BVOA 604 911 913.0 4VE:1008 Type2 Inactive DFGout 13.04 10.245 BBAminus -131.67, -169.88 -148.27, 100.79 -82.62, -2.96 286.91, 95.5 79.99, -173.7 in-in in 8.51 Saltbr-in 2.904 HRD-in -72.24, -49.17 82.06, -11.33 in-out-in SNCioi out-in ActLoopNT-out 18.239 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.68, 131.23 APE9-dihe-in -126.14, 121.66 APE8-dihe-in -79.4, 66.16 APE8-rot-na 32.19 APE67-dihe-in -71.07, -11.16 -57.53, -32.42 APE12-dist-na 13.4 APE11-dist-na 10.402 APE10-dist-na 5.804 APE9-dist-in 7.548 None None None XRAY 1.98 0.197 0.246 A 324 276 32 0 0 0 [[610, 907]] 1.0 5bvo TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5FDPA 604 912 913.0 5WR:1001 Type2 Inactive DFGout 12.864 10.55 BBAminus -127.1, -169.55 -156.77, 102.69 -88.64, -15.81 287.9, 80.85 71.64, -126.66 in-in in 8.682 Saltbr-in 2.817 HRD-in -55.1, -52.04 79.54, -15.81 in-out-in SNCioi out-in ActLoopNT-out 18.209 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.12, 105.18 APE9-dihe-in -112.47, 149.42 APE8-dihe-in -88.32, 64.89 APE8-rot-na 33.93 APE67-dihe-in -69.76, -12.83 -47.87, -35.78 APE12-dist-na 13.662 APE11-dist-na 12.567 APE10-dist-na 7.795 APE9-dist-in 7.281 None None None XRAY 2.25 0.191 0.269 A 337 285 24 0 0 0 [[610, 907]] 1.0 5fdp TYR_DDR1_HUMAN TYR 1.9e-92 315.2 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5FDXA 604 909 913.0 5X1:1001 Type2 Inactive DFGout 13.692 10.636 BBAminus -121.12, -162.24 -166.8, 109.22 -90.51, -4.39 285.67, 84.08 70.34, -138.61 in-in in 8.929 Saltbr-in 3.011 HRD-in -68.9, -39.66 69.06, -22.96 in-out-in SNCioi out-in ActLoopNT-out 18.501 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.42, 112.22 APE9-dihe-in -125.9, 143.59 APE8-dihe-in -89.42, 67.04 APE8-rot-na 25.31 APE67-dihe-in -68.19, -15.78 -47.28, -35.42 APE12-dist-na 15.498 APE11-dist-na 11.994 APE10-dist-na 7.172 APE9-dist-in 7.372 None None None XRAY 2.65 0.198 0.273 A 337 280 26 0 0 0 [[610, 907]] 1.0 5fdx TYR_DDR1_HUMAN TYR 1.9e-92 315.2 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5FDXB 605 907 913.0 5X1:1001 Type2 Inactive DFGout 13.662 11.374 BBAminus -145.36, -178.38 -150.73, 112.04 -97.13, 1.63 283.29, 85.34 70.48, -149.96 in-in in 8.501 Saltbr-in 2.806 HRD-in -69.71, -47.52 76.97, -7.19 in-out-in SNCioi out-in ActLoopNT-out 18.352 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.98, 120.89 APE9-dihe-in -122.23, 132.83 APE8-dihe-in -89.51, 66.4 APE8-rot-na 19.94 APE67-dihe-in -82.06, -13.75 -50.39, -21.97 APE12-dist-na 14.424 APE11-dist-na 11.176 APE10-dist-na 6.586 APE9-dist-in 7.412 None None None XRAY 2.65 0.198 0.273 B 337 274 29 0 0 0 [[610, 907]] 1.0 5fdx TYR_DDR1_HUMAN TYR 1.9e-92 315.2 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
3ZOSA 602 913 913.0 0LI:61000,0LI:61004 Type2,Allosteric Inactive DFGout 13.684 9.765 BBAminus -140.01, 179.9 -153.22, 112.84 -85.26, -13.51 285.68, 107.96 48.92, -126.09 in-in in 7.998 Saltbr-in 2.881 HRD-in -61.25, -58.95 80.5, -7.41 in-out-in SNCioi out-in ActLoopNT-out 17.476 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.17, 140.69 APE9-dihe-in -129.43, 143.43 APE8-dihe-in -82.4, 69.11 APE8-rot-na 29.15 APE67-dihe-in -67.51, -15.14 -58.33, -33.07 APE12-dist-na 11.707 APE11-dist-na 12.385 APE10-dist-na 10.171 APE9-dist-in 7.92 None None None XRAY 1.92 0.208 0.234 A 315 301 11 0 0 0 [[610, 907]] 1.0 3zos TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
7FEHA 603 912 913.0 3UI:1001 Type3 Inactive DFGout 14.614 10.976 BBAminus -140.43, -166.19 -155.59, 100.98 -76.78, -5.55 282.16, 80.98 68.97, 34.94 in-in in 8.239 Saltbr-in 2.707 HRD-in -73.62, -47.42 78.59, -7.41 in-out-in SNCioi out-in ActLoopNT-out 18.36 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.1, 130.52 APE9-dihe-in -126.17, 127.16 APE8-dihe-in -82.15, 70.85 APE8-rot-na 34.51 APE67-dihe-in -74.2, -7.26 -55.53, -34.86 APE12-dist-na 14.424 APE11-dist-na 11.384 APE10-dist-na 6.966 APE9-dist-in 7.347 None None None XRAY 1.61 0.168 0.206 A 320 293 11 0 0 0 [[610, 907]] 1.0 7feh TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5BVWA 604 911 913.0 1N1:1009 Type1 Inactive DFGout 14.538 10.296 None -113.16, 175.58 -102.37, -21.68 40.34, 118.5 221.24, 85.03 -134.54, 999.0 in-in in 8.334 Saltbr-in 2.775 HRD-in -77.35, -46.96 73.51, -12.24 in-none-in SNCini none-in ActLoopNT-none 999.0 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.96, 123.56 APE9-dihe-in -122.26, 123.59 APE8-dihe-in -77.84, 65.49 APE8-rot-na 31.29 APE67-dihe-in -69.31, -14.79 -54.53, -34.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.409 None None None XRAY 1.94 0.186 0.234 A 324 274 34 0 0 4 [[610, 907]] 1.0 5bvw TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5SB2A 603 912 913.0 1K2:61006 Type2 Inactive DFGout 14.448 10.186 None -128.08, -173.69 -153.09, 93.83 -160.14, 172.71 82.61, 105.82 61.28, 40.31 in-in in 7.855 Saltbr-in 3.001 HRD-in -69.91, -51.28 81.29, -13.08 in-out-in SNCioi out-in ActLoopNT-out 19.012 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.61, 119.37 APE9-dihe-in -119.36, 130.38 APE8-dihe-in -84.14, 70.98 APE8-rot-na 33.98 APE67-dihe-in -74.68, -13.47 -62.62, -26.5 APE12-dist-na 14.893 APE11-dist-na 11.7 APE10-dist-na 7.227 APE9-dist-in 7.3 None None None XRAY 1.6 0.209 0.232 A 321 286 18 0 0 0 [[610, 907]] 1.0 5sb2 TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
5BVKA 604 911 913.0 4VC:1007 Type3 Inactive DFGout 12.534 10.223 None -129.55, -176.3 -140.67, 98.58 -92.44, 131.08 301.57, 107.64 -55.47, -44.27 in-in in 8.231 Saltbr-in 2.779 HRD-in -71.41, -52.83 83.7, -18.63 in-out-in SNCioi out-in ActLoopNT-out 15.725 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -83.83, 116.31 APE9-dihe-in -112.39, 120.52 APE8-dihe-in -71.84, 64.33 APE8-rot-na 29.08 APE67-dihe-in -73.09, -12.57 -54.87, -32.03 APE12-dist-na 18.806 APE11-dist-na 15.611 APE10-dist-na 11.342 APE9-dist-in 7.263 None None None XRAY 2.29 0.19 0.232 A 324 278 30 0 0 0 [[610, 907]] 1.0 5bvk TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1

TYR_DDR1 (Epithelial discoidin domain-containing receptor 1)

Total number of chains: 43
Active chains: 2
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 33 76.7% 6FIOA
DFGinter None 5 11.6% 6Y23A
DFGout None 3 7.0% 5SB2A
DFGin BLAminus 2 4.7% AF-Q08345-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
DDR1_HUMAN AF-Q08345-K1A Q08345 602 913 913.0 No_ligand No_ligand Active DFGin 6.776 14.251 BLAminus -135.06, -174.55 56.07, 67.13 -83.23, 9.34 288.88, 95.5 -59.59, -35.2 in-in in 8.306 Saltbr-in 2.737 HRD-in -72.01, -45.8 68.4, -12.55 in-in-in SNCiii in-in ActLoopNT-in 2.867 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.29, 116.83 APE9-dihe-in -129.69, 149.29 APE8-dihe-in -78.52, 77.08 APE8-rot-na 37.11 APE67-dihe-in -70.63, -17.98 -53.54, -33.2 APE12-dist-na 13.882 APE11-dist-na 8.242 APE10-dist-na 10.03 APE9-dist-in 6.189 None None None AF2 -1.0 1.0 1.0 A 312 312 0 0 0 0 [[610, 907]] 1.0 AF-Q08345-K1 Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.6 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN AF-Q08345-K3A Q08345 602 913 913.0 No_ligand No_ligand Active DFGin 6.302 14.228 BLAminus -132.1, -173.2 56.14, 63.84 -78.09, 7.68 289.83, 94.44 -56.87, -37.29 in-in in 8.688 Saltbr-in 2.81 HRD-in -76.69, -47.13 69.33, -1.74 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.95, 123.42 APE9-dihe-in -118.26, 146.05 APE8-dihe-in -78.02, 73.53 APE8-rot-na 35.43 APE67-dihe-in -67.28, -19.02 -51.2, -30.77 APE12-dist-na 14.744 APE11-dist-na 9.296 APE10-dist-na 11.48 APE9-dist-in 6.828 None None None AF2 -1.0 1.0 1.0 A 312 312 0 0 0 0 [[610, 907]] 1.0 AF-Q08345-K3 Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.6 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6Y23A Q08345 574 907 913.0 No_ligand No_ligand Inactive DFGinter 10.153 7.308 None -140.3, -158.95 -155.89, 34.86 -96.49, -19.82 306.08, 111.29 -54.16, -38.8 in-out in 7.431 Saltbr-out 4.303 HRD-in -69.02, -55.97 80.69, 2.43 out-out-in SNCooi out-in ActLoopNT-out 17.592 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -133.93, 116.48 APE9-dihe-in -127.74, 145.71 APE8-dihe-in -88.51, 68.54 APE8-rot-na 35.64 APE67-dihe-in -68.64, -17.14 -58.48, -33.24 APE12-dist-na 999.0 APE11-dist-na 12.248 APE10-dist-na 7.88 APE9-dist-in 7.176 Y569F,Y586F None None XRAY 2.58 0.228 0.27 A 350 305 27 0 0 3 [[610, 907]] 1.0 6y23 Homo sapiens TYR_DDR1_HUMAN TYR 2.2e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6Y23B Q08345 574 910 913.0 No_ligand No_ligand Inactive DFGinter 10.177 7.489 None -147.65, -164.17 -143.7, 24.01 -83.51, -17.89 309.63, 115.78 -53.01, -42.7 in-out in 7.401 Saltbr-out 4.538 HRD-in -62.79, -53.56 80.0, -6.1 out-out-none SNCoon out-none ActLoopNT-out 17.396 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 122.54 APE9-dihe-in -139.37, 143.31 APE8-dihe-in -88.22, 70.91 APE8-rot-na 34.24 APE67-dihe-in -65.16, -14.5 -56.89, -35.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 7.79 APE9-dist-in 7.245 Y569F,Y586F None None XRAY 2.58 0.228 0.27 B 350 301 30 0 0 5 [[610, 907]] 1.0 6y23 Homo sapiens TYR_DDR1_HUMAN TYR 2.2e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6Y23C Q08345 574 911 913.0 No_ligand No_ligand Inactive DFGinter 10.326 7.424 None -131.36, -161.95 -146.38, 29.72 -92.15, -18.74 310.61, 115.72 -49.18, -37.85 in-out in 7.603 Saltbr-out 5.078 HRD-in -65.34, -54.8 81.25, 2.61 out-out-none SNCoon out-none ActLoopNT-out 17.518 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 131.97 APE9-dihe-in -138.28, 145.82 APE8-dihe-in -85.36, 72.32 APE8-rot-na 34.45 APE67-dihe-in -71.14, -17.59 -62.42, -29.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 8.108 APE9-dist-in 7.111 Y569F,Y586F None None XRAY 2.58 0.228 0.27 C 350 305 33 0 0 5 [[610, 907]] 1.0 6y23 Homo sapiens TYR_DDR1_HUMAN TYR 2.2e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6BRJA Q08345 605 913 913.0 VX6:60901 Type1 Inactive DFGinter 9.842 6.444 None -75.98, 130.59 -108.73, 22.4 -131.46, 172.46 67.8, 95.77 -125.27, 159.76 in-in in 8.607 Saltbr-in 2.475 HRD-in -69.59, -46.48 76.5, -9.43 in-out-in SNCioi out-in ActLoopNT-out 18.162 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.43, 114.86 APE9-dihe-in -119.04, 131.61 APE8-dihe-in -82.29, 70.03 APE8-rot-na 39.02 APE67-dihe-in -70.78, -15.74 -55.16, -32.48 APE12-dist-na 18.237 APE11-dist-na 14.849 APE10-dist-na 11.084 APE9-dist-in 7.365 None None None XRAY 2.231 0.189 0.223 A 351 274 35 0 0 0 [[610, 907]] 1.0 6brj Homo sapiens TYR_DDR1_HUMAN TYR 2.3e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6BSDA Q08345 604 912 913.0 1N1:60901 Type1 Inactive DFGinter 9.948 9.844 None -87.87, 155.34 -64.16, -24.42 174.69, 170.82 68.3, 89.44 55.93, 999.0 in-in in 8.37 Saltbr-in 2.735 HRD-in -61.68, -56.93 83.98, -4.33 in-out-in SNCioi out-in ActLoopNT-out 19.848 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.74, 115.57 APE9-dihe-in -116.16, 127.65 APE8-dihe-in -81.76, 68.68 APE8-rot-na 34.21 APE67-dihe-in -66.93, -20.25 -61.43, -30.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.146 None None None XRAY 2.606 0.186 0.255 A 351 278 31 0 0 2 [[610, 907]] 1.0 6bsd Homo sapiens TYR_DDR1_HUMAN TYR 2.3e-92 315.0 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SAUA Q08345 604 912 913.0 1IF:61000 Type2 Inactive DFGout 12.628 9.672 BBAminus -137.39, -170.54 -153.95, 108.1 -100.48, 5.9 289.81, 101.12 83.39, -174.73 in-in in 8.355 Saltbr-in 2.869 HRD-in -71.66, -48.67 82.15, -10.52 in-out-in SNCioi out-in ActLoopNT-out 18.139 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.56, 139.94 APE9-dihe-in -129.66, 123.98 APE8-dihe-in -80.56, 70.77 APE8-rot-na 35.49 APE67-dihe-in -73.85, -9.33 -63.13, -31.85 APE12-dist-na 13.331 APE11-dist-na 10.312 APE10-dist-na 5.884 APE9-dist-in 7.555 None None None XRAY 1.8 0.201 0.231 A 321 287 16 0 0 0 [[610, 907]] 1.0 5sau Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SAVA Q08345 602 909 913.0 1IJ:61001 Type2 Inactive DFGout 12.249 9.892 BBAminus -137.58, -169.64 -150.62, 110.81 -103.5, 11.77 291.8, 111.79 80.59, -174.76 in-in in 8.531 Saltbr-in 2.847 HRD-in -72.55, -49.58 80.09, -14.29 in-out-in SNCioi out-in ActLoopNT-out 18.108 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.25, 135.7 APE9-dihe-in -126.66, 126.5 APE8-dihe-in -76.9, 69.2 APE8-rot-na 29.65 APE67-dihe-in -68.15, -12.71 -57.84, -36.12 APE12-dist-na 13.471 APE11-dist-na 10.502 APE10-dist-na 6.037 APE9-dist-in 7.293 None None None XRAY 1.76 0.195 0.235 A 321 291 11 0 0 0 [[610, 907]] 1.0 5sav Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SAWA Q08345 603 907 913.0 1IM:61001 Type2 Inactive DFGout 12.493 9.439 BBAminus -136.32, -167.56 -154.42, 105.26 -96.79, 11.36 288.89, 101.22 78.08, -173.73 in-in in 8.104 Saltbr-in 2.688 HRD-in -72.41, -49.17 82.35, -13.45 in-out-in SNCioi out-in ActLoopNT-out 18.003 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.99, 135.55 APE9-dihe-in -127.2, 125.08 APE8-dihe-in -79.96, 65.74 APE8-rot-na 30.31 APE67-dihe-in -73.33, -9.46 -58.7, -30.17 APE12-dist-na 13.306 APE11-dist-na 10.135 APE10-dist-na 5.737 APE9-dist-in 7.441 None None None XRAY 1.601 0.201 0.226 A 321 291 8 0 0 0 [[610, 907]] 1.0 5saw Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SAXA Q08345 601 913 913.0 1IM:61009 Type2 Inactive DFGout 12.785 9.652 BBAminus -136.63, -167.06 -151.99, 103.38 -94.74, 11.71 289.58, 96.46 77.91, -172.64 in-in in 8.233 Saltbr-in 2.686 HRD-in -70.12, -47.49 78.55, -13.59 in-out-in SNCioi out-in ActLoopNT-out 18.058 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.48, 134.35 APE9-dihe-in -127.3, 128.21 APE8-dihe-in -84.18, 72.54 APE8-rot-na 32.87 APE67-dihe-in -73.3, -15.34 -61.77, -28.17 APE12-dist-na 13.332 APE11-dist-na 10.305 APE10-dist-na 5.824 APE9-dist-in 7.44 None None None XRAY 1.902 0.212 0.254 A 321 302 5 0 0 0 [[610, 907]] 1.0 5sax Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SAYA Q08345 602 907 913.0 1IJ:61009 Type2 Inactive DFGout 13.11 10.338 BBAminus -139.08, -171.59 -152.18, 105.65 -84.47, 2.41 293.81, 95.27 76.78, -161.44 in-in in 8.613 Saltbr-in 2.856 HRD-in -76.95, -56.11 85.16, -6.58 in-out-in SNCioi out-in ActLoopNT-out 18.086 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.13, 129.59 APE9-dihe-in -128.34, 133.74 APE8-dihe-in -84.79, 68.27 APE8-rot-na 30.95 APE67-dihe-in -71.25, -15.06 -62.46, -28.48 APE12-dist-na 13.985 APE11-dist-na 10.957 APE10-dist-na 6.246 APE9-dist-in 7.324 None None None XRAY 2.19 0.206 0.277 A 321 290 10 0 0 0 [[610, 907]] 1.0 5say Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SAYB Q08345 602 911 913.0 1IJ:61008 Type2 Inactive DFGout 12.9 9.62 BBAminus -142.01, -168.91 -152.05, 105.38 -85.39, 0.61 294.66, 96.94 74.6, -161.8 in-in in 8.465 Saltbr-in 2.871 HRD-in -72.03, -52.9 85.69, -8.23 in-out-in SNCioi out-in ActLoopNT-out 18.068 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.08, 123.36 APE9-dihe-in -135.38, 149.1 APE8-dihe-in -77.36, 69.77 APE8-rot-na 31.97 APE67-dihe-in -71.49, -13.73 -62.32, -28.79 APE12-dist-na 14.317 APE11-dist-na 10.434 APE10-dist-na 6.946 APE9-dist-in 7.157 None None None XRAY 2.19 0.206 0.277 B 321 288 16 0 0 0 [[610, 907]] 1.0 5say Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SAZA Q08345 603 913 913.0 1IW:61001 Type2 Inactive DFGout 13.69 10.143 BBAminus -137.95, -165.09 -152.44, 116.71 -99.61, 2.45 287.9, 84.51 75.93, -173.07 in-in in 8.329 Saltbr-in 2.833 HRD-in -71.16, -46.01 79.1, -11.15 in-out-in SNCioi out-in ActLoopNT-out 18.097 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.41, 142.17 APE9-dihe-in -131.47, 123.66 APE8-dihe-in -78.39, 69.53 APE8-rot-na 32.74 APE67-dihe-in -72.73, -11.69 -61.24, -31.8 APE12-dist-na 13.182 APE11-dist-na 10.338 APE10-dist-na 5.805 APE9-dist-in 7.413 None None None XRAY 1.8 0.189 0.224 A 321 290 15 0 0 0 [[610, 907]] 1.0 5saz Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SB0A Q08345 604 913 913.0 1IZ:61002 Type2 Inactive DFGout 14.205 11.415 BBAminus -134.1, -167.44 -149.3, 103.34 -77.41, -7.41 286.62, 82.49 82.96, -174.18 in-in in 7.949 Saltbr-in 2.485 HRD-in -69.43, -51.57 85.83, -12.36 in-out-in SNCioi out-in ActLoopNT-out 18.072 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.15, 129.55 APE9-dihe-in -121.03, 123.84 APE8-dihe-in -76.55, 70.49 APE8-rot-na 28.9 APE67-dihe-in -76.04, -15.35 -65.09, -25.8 APE12-dist-na 13.681 APE11-dist-na 10.691 APE10-dist-na 6.122 APE9-dist-in 7.406 None None None XRAY 1.97 0.21 0.256 A 321 284 20 0 0 0 [[610, 907]] 1.0 5sb0 Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SB1A Q08345 604 913 913.0 1JI:61001 Type2 Inactive DFGout 12.791 10.273 BBAminus -136.97, -163.16 -159.21, 109.76 -101.99, 10.87 293.72, 105.65 82.9, -171.77 in-in in 7.861 Saltbr-in 2.936 HRD-in -69.06, -48.99 77.38, -14.74 in-out-in SNCioi out-in ActLoopNT-out 18.198 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.56, 137.83 APE9-dihe-in -127.95, 125.11 APE8-dihe-in -81.37, 69.62 APE8-rot-na 31.59 APE67-dihe-in -73.44, -13.11 -59.21, -30.91 APE12-dist-na 13.149 APE11-dist-na 10.252 APE10-dist-na 5.706 APE9-dist-in 7.394 None None None XRAY 1.53 0.19 0.214 A 321 284 20 0 0 0 [[610, 907]] 1.0 5sb1 Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6FEWA Q08345 603 911 913.0 D6W:1001 Type2 Inactive DFGout 14.639 11.11 BBAminus -123.11, -164.13 -159.89, 87.13 -66.29, -19.31 278.92, 81.95 89.37, -178.21 in-in in 8.229 Saltbr-in 2.638 HRD-in -71.95, -50.33 82.89, -15.2 in-out-in SNCioi out-in ActLoopNT-out 18.323 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.78, 132.51 APE9-dihe-in -128.37, 122.79 APE8-dihe-in -77.16, 68.85 APE8-rot-na 31.54 APE67-dihe-in -72.02, -12.2 -55.39, -33.21 APE12-dist-na 13.445 APE11-dist-na 10.428 APE10-dist-na 5.901 APE9-dist-in 7.391 None None None XRAY 1.44 0.218 0.241 A 321 291 12 0 0 0 [[610, 907]] 1.0 6few Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6FEXA Q08345 602 908 913.0 D6Z:1001 Type2 Inactive DFGout 15.369 10.952 BBAminus -128.49, -167.33 -156.07, 92.0 -71.27, -9.26 285.23, 81.96 80.6, -168.82 in-in in 8.315 Saltbr-in 2.793 HRD-in -70.39, -48.84 82.04, -14.46 in-out-in SNCioi out-in ActLoopNT-out 18.284 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.0, 135.5 APE9-dihe-in -130.56, 128.86 APE8-dihe-in -81.39, 69.61 APE8-rot-na 31.4 APE67-dihe-in -70.03, -14.92 -58.59, -34.04 APE12-dist-na 13.49 APE11-dist-na 10.369 APE10-dist-na 5.964 APE9-dist-in 7.383 None None None XRAY 1.291 0.139 0.174 A 321 289 12 0 0 0 [[610, 907]] 1.0 6fex Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6FILA Q08345 604 912 913.0 D6W:61001 Type2 Inactive DFGout 14.441 11.42 BBAminus -114.42, -165.45 -157.03, 86.17 -70.37, -21.94 279.41, 75.3 87.75, -166.46 in-in in 8.01 Saltbr-in 2.679 HRD-in -76.68, -51.8 78.33, -9.55 in-out-in SNCioi out-in ActLoopNT-out 18.428 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.44, 131.81 APE9-dihe-in -123.24, 125.33 APE8-dihe-in -80.01, 68.23 APE8-rot-na 31.21 APE67-dihe-in -71.92, -14.88 -58.1, -31.6 APE12-dist-na 13.401 APE11-dist-na 10.53 APE10-dist-na 6.031 APE9-dist-in 7.265 None None None XRAY 1.73 0.195 0.245 A 321 287 16 0 0 0 [[610, 907]] 1.0 6fil Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6FINA Q08345 603 911 913.0 DJQ:1009 Type2 Inactive DFGout 14.863 11.317 BBAminus -129.33, -165.3 -156.6, 92.58 -69.92, -11.44 280.96, 78.02 83.02, -169.31 in-in in 8.294 Saltbr-in 2.765 HRD-in -73.9, -50.38 81.4, -14.94 in-out-in SNCioi out-in ActLoopNT-out 18.495 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.7, 130.0 APE9-dihe-in -127.24, 126.8 APE8-dihe-in -81.19, 70.61 APE8-rot-na 30.53 APE67-dihe-in -74.43, -13.11 -58.96, -28.14 APE12-dist-na 13.715 APE11-dist-na 10.613 APE10-dist-na 6.156 APE9-dist-in 7.388 None None None XRAY 1.67 0.2 0.228 A 321 294 9 0 0 0 [[610, 907]] 1.0 6fin Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6FIOA Q08345 598 912 913.0 DJH:61001 Type2 Inactive DFGout 15.177 11.002 BBAminus -127.61, -164.73 -159.21, 87.63 -74.98, -16.13 283.57, 78.17 77.22, -166.77 in-in in 8.573 Saltbr-in 3.003 HRD-in -72.35, -48.97 77.34, -11.82 in-out-in SNCioi out-in ActLoopNT-out 18.741 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.31, 116.38 APE9-dihe-in -134.04, 158.77 APE8-dihe-in -82.95, 69.6 APE8-rot-na 34.53 APE67-dihe-in -69.65, -14.77 -56.14, -33.27 APE12-dist-na 15.393 APE11-dist-na 11.087 APE10-dist-na 7.959 APE9-dist-in 7.39 None None None XRAY 1.99 0.217 0.277 A 321 307 2 0 0 0 [[610, 907]] 1.0 6fio Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6FIQA Q08345 601 913 913.0 DJW:61001 Type2 Inactive DFGout 15.147 11.659 BBAminus -129.66, -164.81 -158.71, 85.69 -65.74, -18.84 287.76, 69.48 91.48, -171.72 in-in in 8.191 Saltbr-in 2.905 HRD-in -74.98, -49.59 81.33, -13.91 in-out-out SNCioo out-out ActLoopNT-out 18.338 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -135.13, -40.38 APE9-dihe-in -138.98, 126.92 APE8-dihe-in -80.25, 71.05 APE8-rot-na 32.35 APE67-dihe-in -73.93, -12.67 -61.47, -27.84 APE12-dist-na 8.863 APE11-dist-na 4.817 APE10-dist-na 8.84 APE9-dist-in 7.348 None None None XRAY 1.79 0.201 0.238 A 321 293 14 0 0 0 [[610, 907]] 1.0 6fiq Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 3ZOSB Q08345 601 913 913.0 0LI:61000 Type2 Inactive DFGout 13.646 9.63 BBAminus -143.84, 178.94 -153.3, 114.42 -82.71, -15.18 287.49, 108.73 52.14, -127.46 in-in in 7.96 Saltbr-in 2.883 HRD-in -60.43, -59.89 83.25, -8.8 in-out-in SNCioi out-in ActLoopNT-out 17.4 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.91, 133.24 APE9-dihe-in -130.81, 142.32 APE8-dihe-in -80.63, 68.61 APE8-rot-na 30.08 APE67-dihe-in -67.12, -16.99 -59.3, -31.33 APE12-dist-na 11.719 APE11-dist-na 12.939 APE10-dist-na 10.223 APE9-dist-in 7.924 None None None XRAY 1.92 0.208 0.234 B 315 301 12 0 0 0 [[610, 907]] 1.0 3zos Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 4BKJA Q08345 601 913 913.0 STI:61000 Type2 Inactive DFGout 13.041 10.869 BBAminus -135.57, -177.41 -150.26, 104.38 -97.26, -19.55 309.91, 132.36 76.19, -179.07 in-in in 8.056 Saltbr-in 2.781 HRD-in -73.25, -56.55 82.61, -12.77 in-out-in SNCioi out-in ActLoopNT-out 18.428 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.84, 113.6 APE9-dihe-in -132.17, 138.55 APE8-dihe-in -81.73, 66.81 APE8-rot-na 30.65 APE67-dihe-in -70.94, -16.71 -56.41, -32.35 APE12-dist-na 999.0 APE11-dist-na 10.43 APE10-dist-na 6.399 APE9-dist-in 7.253 None None None XRAY 1.7 0.157 0.176 A 315 294 19 0 0 4 [[610, 907]] 1.0 4bkj Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 4BKJB Q08345 601 913 913.0 STI:61000 Type2 Inactive DFGout 12.942 10.696 BBAminus -134.88, -177.2 -150.26, 104.51 -98.15, -18.24 308.85, 133.85 76.2, -180.0 in-in in 8.078 Saltbr-in 2.781 HRD-in -71.4, -58.01 82.61, -12.4 in-out-in SNCioi out-in ActLoopNT-out 18.43 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.57, 113.98 APE9-dihe-in -133.47, 139.44 APE8-dihe-in -81.51, 65.72 APE8-rot-na 30.98 APE67-dihe-in -69.17, -18.25 -55.39, -33.59 APE12-dist-na 999.0 APE11-dist-na 10.754 APE10-dist-na 6.412 APE9-dist-in 7.213 None None None XRAY 1.7 0.157 0.176 B 315 296 17 0 0 4 [[610, 907]] 1.0 4bkj Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 4CKRA Q08345 601 913 913.0 DI1:61000 Type2 Inactive DFGout 13.862 11.486 BBAminus -138.41, 172.1 -152.04, 104.0 -83.41, -39.47 307.21, 120.94 70.34, 17.44 in-in in 8.355 Saltbr-in 2.772 HRD-in -71.2, -61.64 87.29, -10.58 in-out-none SNCion out-none ActLoopNT-out 18.85 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 114.24 APE9-dihe-in -144.37, 137.98 APE8-dihe-in -80.98, 66.37 APE8-rot-na 31.95 APE67-dihe-in -71.92, -18.62 -58.18, -30.83 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.291 APE9-dist-in 7.341 None None None XRAY 2.2 0.201 0.247 A 315 294 19 0 0 4 [[610, 907]] 1.0 4ckr Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6GWRA Q08345 601 912 913.0 FEW:61001 Type2 Inactive DFGout 12.8 10.684 BBAminus -134.05, -169.98 -156.8, 106.42 -94.1, 5.66 291.49, 91.7 63.63, -138.67 in-in in 8.986 Saltbr-in 3.053 HRD-in -67.39, -50.22 80.83, -8.55 in-out-in SNCioi out-in ActLoopNT-out 18.628 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -127.27, 154.82 APE9-dihe-in -127.56, 142.54 APE8-dihe-in -85.13, 70.94 APE8-rot-na 33.79 APE67-dihe-in -68.94, -16.33 -59.49, -34.74 APE12-dist-na 9.487 APE11-dist-na 10.655 APE10-dist-na 7.462 APE9-dist-in 7.06 None None None XRAY 2.07 0.202 0.237 A 315 299 13 0 0 0 [[610, 907]] 1.0 6gwr Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6GWRB Q08345 602 908 913.0 FEW:61001 Type2 Inactive DFGout 13.011 10.839 BBAminus -135.63, -168.81 -156.8, 100.71 -86.26, 0.96 289.39, 87.09 64.13, -147.41 in-in in 8.594 Saltbr-in 2.936 HRD-in -66.48, -54.41 81.91, -7.37 in-out-in SNCioi out-in ActLoopNT-out 18.469 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -127.74, 153.56 APE9-dihe-in -126.55, 140.43 APE8-dihe-in -85.27, 72.54 APE8-rot-na 32.6 APE67-dihe-in -67.25, -20.33 -64.19, -32.01 APE12-dist-na 9.364 APE11-dist-na 10.87 APE10-dist-na 7.365 APE9-dist-in 6.94 None None None XRAY 2.07 0.202 0.237 B 315 285 22 0 0 0 [[610, 907]] 1.0 6gwr Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6HP9A Q08345 601 909 913.0 GKB:61001 Type2 Inactive DFGout 13.913 10.926 BBAminus -145.6, -172.43 -152.86, 103.11 -77.98, 3.78 281.96, 79.76 68.1, -156.94 in-in in 8.49 Saltbr-in 2.724 HRD-in -65.95, -51.98 77.73, -3.58 in-out-in SNCioi out-in ActLoopNT-out 18.268 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -129.05, 129.39 APE9-dihe-in -127.0, 142.65 APE8-dihe-in -84.02, 69.07 APE8-rot-na 35.45 APE67-dihe-in -67.82, -15.87 -61.84, -33.19 APE12-dist-na 13.79 APE11-dist-na 10.502 APE10-dist-na 6.772 APE9-dist-in 7.205 None None None XRAY 1.96 0.207 0.251 A 315 295 14 0 0 0 [[610, 907]] 1.0 6hp9 Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 6HP9B Q08345 603 909 913.0 GKB:61001 Type2 Inactive DFGout 13.937 11.029 BBAminus -138.11, -164.71 -161.75, 101.28 -81.09, 0.81 285.57, 77.73 64.83, 177.38 in-in in 8.384 Saltbr-in 2.872 HRD-in -72.07, -47.03 76.05, -7.83 in-out-in SNCioi out-in ActLoopNT-out 18.187 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.8, 132.01 APE9-dihe-in -133.29, 124.1 APE8-dihe-in -79.54, 70.21 APE8-rot-na 34.04 APE67-dihe-in -72.05, -14.89 -58.92, -31.44 APE12-dist-na 14.023 APE11-dist-na 10.867 APE10-dist-na 6.428 APE9-dist-in 7.303 None None None XRAY 1.96 0.207 0.251 B 315 281 26 0 0 0 [[610, 907]] 1.0 6hp9 Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 7BCMA Q08345 604 909 913.0 TBK:1001 Type2 Inactive DFGout 13.008 10.093 BBAminus -144.68, -175.9 -143.48, 102.2 -83.62, 3.62 287.6, 81.94 81.32, -168.03 in-in in 8.656 Saltbr-in 3.009 HRD-in -65.71, -55.98 87.34, -19.67 in-out-in SNCioi out-in ActLoopNT-out 18.307 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.26, 137.51 APE9-dihe-in -123.82, 128.63 APE8-dihe-in -86.21, 69.22 APE8-rot-na 27.2 APE67-dihe-in -71.43, -12.52 -62.93, -34.22 APE12-dist-na 13.45 APE11-dist-na 10.503 APE10-dist-na 6.276 APE9-dist-in 7.552 None None None XRAY 2.3 0.246 0.308 A 315 273 33 0 0 0 [[610, 907]] 1.0 7bcm Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 7BCMB Q08345 604 911 913.0 TBK:1001 Type2 Inactive DFGout 12.873 10.003 BBAminus -131.16, -172.17 -135.77, 109.56 -94.04, -4.34 282.79, 103.01 90.67, -179.36 in-out in 8.369 Saltbr-out 3.617 HRD-in -62.88, -55.49 80.94, -21.01 out-out-in SNCooi out-in ActLoopNT-out 18.345 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.26, 139.25 APE9-dihe-in -129.42, 124.32 APE8-dihe-in -81.31, 68.14 APE8-rot-na 36.31 APE67-dihe-in -65.99, -20.67 -66.61, -29.37 APE12-dist-na 13.249 APE11-dist-na 10.653 APE10-dist-na 5.986 APE9-dist-in 7.524 None None None XRAY 2.3 0.246 0.308 B 315 266 42 0 0 0 [[610, 907]] 1.0 7bcm Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 7BE6A Q08345 601 912 913.0 TJW:61009 Type2 Inactive DFGout 13.274 10.693 BBAminus -133.78, -166.84 -149.99, 107.57 -92.55, -8.19 288.48, 90.78 60.12, -147.46 in-in in 8.551 Saltbr-in 2.9 HRD-in -70.89, -50.95 79.48, -10.8 in-out-in SNCioi out-in ActLoopNT-out 19.026 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -130.64, 162.67 APE9-dihe-in -137.45, 131.08 APE8-dihe-in -82.5, 71.83 APE8-rot-na 34.81 APE67-dihe-in -72.32, -17.47 -59.41, -30.72 APE12-dist-na 10.476 APE11-dist-na 11.104 APE10-dist-na 7.021 APE9-dist-in 7.285 None None None XRAY 1.871 0.189 0.23 A 315 301 11 0 0 0 [[610, 907]] 1.0 7be6 Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5BVNA Q08345 604 911 913.0 4VD:1002 Type2 Inactive DFGout 12.52 10.864 BBAminus -133.48, -169.53 -151.91, 105.04 -95.23, 10.51 304.6, 110.5 72.08, -162.27 in-in in 8.622 Saltbr-in 2.79 HRD-in -66.14, -48.88 77.95, -15.06 in-out-in SNCioi out-in ActLoopNT-out 18.242 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.29, 133.25 APE9-dihe-in -125.22, 110.99 APE8-dihe-in -73.41, 62.73 APE8-rot-na 28.5 APE67-dihe-in -72.96, -4.61 -50.16, -37.38 APE12-dist-na 13.084 APE11-dist-na 10.346 APE10-dist-na 5.549 APE9-dist-in 7.446 None None None XRAY 2.21 0.256 0.328 A 324 278 30 0 0 0 [[610, 907]] 1.0 5bvn Homo sapiens TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5BVOA Q08345 604 911 913.0 4VE:1008 Type2 Inactive DFGout 13.04 10.245 BBAminus -131.67, -169.88 -148.27, 100.79 -82.62, -2.96 286.91, 95.5 79.99, -173.7 in-in in 8.51 Saltbr-in 2.904 HRD-in -72.24, -49.17 82.06, -11.33 in-out-in SNCioi out-in ActLoopNT-out 18.239 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.68, 131.23 APE9-dihe-in -126.14, 121.66 APE8-dihe-in -79.4, 66.16 APE8-rot-na 32.19 APE67-dihe-in -71.07, -11.16 -57.53, -32.42 APE12-dist-na 13.4 APE11-dist-na 10.402 APE10-dist-na 5.804 APE9-dist-in 7.548 None None None XRAY 1.98 0.197 0.246 A 324 276 32 0 0 0 [[610, 907]] 1.0 5bvo Homo sapiens TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5FDPA Q08345 604 912 913.0 5WR:1001 Type2 Inactive DFGout 12.864 10.55 BBAminus -127.1, -169.55 -156.77, 102.69 -88.64, -15.81 287.9, 80.85 71.64, -126.66 in-in in 8.682 Saltbr-in 2.817 HRD-in -55.1, -52.04 79.54, -15.81 in-out-in SNCioi out-in ActLoopNT-out 18.209 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.12, 105.18 APE9-dihe-in -112.47, 149.42 APE8-dihe-in -88.32, 64.89 APE8-rot-na 33.93 APE67-dihe-in -69.76, -12.83 -47.87, -35.78 APE12-dist-na 13.662 APE11-dist-na 12.567 APE10-dist-na 7.795 APE9-dist-in 7.281 None None None XRAY 2.25 0.191 0.269 A 337 285 24 0 0 0 [[610, 907]] 1.0 5fdp Homo sapiens TYR_DDR1_HUMAN TYR 1.9e-92 315.2 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5FDXA Q08345 604 909 913.0 5X1:1001 Type2 Inactive DFGout 13.692 10.636 BBAminus -121.12, -162.24 -166.8, 109.22 -90.51, -4.39 285.67, 84.08 70.34, -138.61 in-in in 8.929 Saltbr-in 3.011 HRD-in -68.9, -39.66 69.06, -22.96 in-out-in SNCioi out-in ActLoopNT-out 18.501 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.42, 112.22 APE9-dihe-in -125.9, 143.59 APE8-dihe-in -89.42, 67.04 APE8-rot-na 25.31 APE67-dihe-in -68.19, -15.78 -47.28, -35.42 APE12-dist-na 15.498 APE11-dist-na 11.994 APE10-dist-na 7.172 APE9-dist-in 7.372 None None None XRAY 2.65 0.198 0.273 A 337 280 26 0 0 0 [[610, 907]] 1.0 5fdx Homo sapiens TYR_DDR1_HUMAN TYR 1.9e-92 315.2 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5FDXB Q08345 605 907 913.0 5X1:1001 Type2 Inactive DFGout 13.662 11.374 BBAminus -145.36, -178.38 -150.73, 112.04 -97.13, 1.63 283.29, 85.34 70.48, -149.96 in-in in 8.501 Saltbr-in 2.806 HRD-in -69.71, -47.52 76.97, -7.19 in-out-in SNCioi out-in ActLoopNT-out 18.352 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.98, 120.89 APE9-dihe-in -122.23, 132.83 APE8-dihe-in -89.51, 66.4 APE8-rot-na 19.94 APE67-dihe-in -82.06, -13.75 -50.39, -21.97 APE12-dist-na 14.424 APE11-dist-na 11.176 APE10-dist-na 6.586 APE9-dist-in 7.412 None None None XRAY 2.65 0.198 0.273 B 337 274 29 0 0 0 [[610, 907]] 1.0 5fdx Homo sapiens TYR_DDR1_HUMAN TYR 1.9e-92 315.2 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 3ZOSA Q08345 602 913 913.0 0LI:61000,0LI:61004 Type2,Allosteric Inactive DFGout 13.684 9.765 BBAminus -140.01, 179.9 -153.22, 112.84 -85.26, -13.51 285.68, 107.96 48.92, -126.09 in-in in 7.998 Saltbr-in 2.881 HRD-in -61.25, -58.95 80.5, -7.41 in-out-in SNCioi out-in ActLoopNT-out 17.476 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.17, 140.69 APE9-dihe-in -129.43, 143.43 APE8-dihe-in -82.4, 69.11 APE8-rot-na 29.15 APE67-dihe-in -67.51, -15.14 -58.33, -33.07 APE12-dist-na 11.707 APE11-dist-na 12.385 APE10-dist-na 10.171 APE9-dist-in 7.92 None None None XRAY 1.92 0.208 0.234 A 315 301 11 0 0 0 [[610, 907]] 1.0 3zos Homo sapiens TYR_DDR1_HUMAN TYR 1.5e-92 315.5 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 7FEHA Q08345 603 912 913.0 3UI:1001 Type3 Inactive DFGout 14.614 10.976 BBAminus -140.43, -166.19 -155.59, 100.98 -76.78, -5.55 282.16, 80.98 68.97, 34.94 in-in in 8.239 Saltbr-in 2.707 HRD-in -73.62, -47.42 78.59, -7.41 in-out-in SNCioi out-in ActLoopNT-out 18.36 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.1, 130.52 APE9-dihe-in -126.17, 127.16 APE8-dihe-in -82.15, 70.85 APE8-rot-na 34.51 APE67-dihe-in -74.2, -7.26 -55.53, -34.86 APE12-dist-na 14.424 APE11-dist-na 11.384 APE10-dist-na 6.966 APE9-dist-in 7.347 None None None XRAY 1.61 0.168 0.206 A 320 293 11 0 0 0 [[610, 907]] 1.0 7feh Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5BVWA Q08345 604 911 913.0 1N1:1009 Type1 Inactive DFGout 14.538 10.296 None -113.16, 175.58 -102.37, -21.68 40.34, 118.5 221.24, 85.03 -134.54, 999.0 in-in in 8.334 Saltbr-in 2.775 HRD-in -77.35, -46.96 73.51, -12.24 in-none-in SNCini none-in ActLoopNT-none 999.0 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.96, 123.56 APE9-dihe-in -122.26, 123.59 APE8-dihe-in -77.84, 65.49 APE8-rot-na 31.29 APE67-dihe-in -69.31, -14.79 -54.53, -34.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.409 None None None XRAY 1.94 0.186 0.234 A 324 274 34 0 0 4 [[610, 907]] 1.0 5bvw Homo sapiens TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5SB2A Q08345 603 912 913.0 1K2:61006 Type2 Inactive DFGout 14.448 10.186 None -128.08, -173.69 -153.09, 93.83 -160.14, 172.71 82.61, 105.82 61.28, 40.31 in-in in 7.855 Saltbr-in 3.001 HRD-in -69.91, -51.28 81.29, -13.08 in-out-in SNCioi out-in ActLoopNT-out 19.012 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.61, 119.37 APE9-dihe-in -119.36, 130.38 APE8-dihe-in -84.14, 70.98 APE8-rot-na 33.98 APE67-dihe-in -74.68, -13.47 -62.62, -26.5 APE12-dist-na 14.893 APE11-dist-na 11.7 APE10-dist-na 7.227 APE9-dist-in 7.3 None None None XRAY 1.6 0.209 0.232 A 321 286 18 0 0 0 [[610, 907]] 1.0 5sb2 Homo sapiens TYR_DDR1_HUMAN TYR 1.4e-92 315.7 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1
DDR1_HUMAN 5BVKA Q08345 604 911 913.0 4VC:1007 Type3 Inactive DFGout 12.534 10.223 None -129.55, -176.3 -140.67, 98.58 -92.44, 131.08 301.57, 107.64 -55.47, -44.27 in-in in 8.231 Saltbr-in 2.779 HRD-in -71.41, -52.83 83.7, -18.63 in-out-in SNCioi out-in ActLoopNT-out 15.725 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -83.83, 116.31 APE9-dihe-in -112.39, 120.52 APE8-dihe-in -71.84, 64.33 APE8-rot-na 29.08 APE67-dihe-in -73.09, -12.57 -54.87, -32.03 APE12-dist-na 18.806 APE11-dist-na 15.611 APE10-dist-na 11.342 APE9-dist-in 7.263 None None None XRAY 2.29 0.19 0.232 A 324 278 30 0 0 0 [[610, 907]] 1.0 5bvk Homo sapiens TYR_DDR1_HUMAN TYR 1.7e-92 315.4 1 260 260 783 784 785 787 789 655 672 676 763 765 764 766 825 813 808 807 806 805 804 803 802 702 Epithelial discoidin domain-containing receptor 1

TYR_DDR1 (Epithelial discoidin domain-containing receptor 1)

Total number of chains: 0
Active chains: 0
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name