TKL_BMPR2 (Bone morphogenetic protein receptor type-2)

Total number of chains: 6
Active chains: 5
Uniprot: BMPR2_HUMAN
Kinase Domain Residues: 203 - 503
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% AF-Q13873-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2
3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2
6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2
AF-Q13873-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2
AF-Q13873-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2
6UNPA 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii ADP, ADP ATPlike, Allosteric 199 - 509 0 None D485G Bone morphogenetic protein receptor type-2

TKL_BMPR2 (Bone morphogenetic protein receptor type-2)

Total number of chains: 6
Active chains: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% AF-Q13873-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
BMPR2_HUMAN 3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
BMPR2_HUMAN 3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
BMPR2_HUMAN 6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2 Homo sapiens
BMPR2_HUMAN AF-Q13873-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
BMPR2_HUMAN AF-Q13873-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
BMPR2_HUMAN 6UNPA 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii ADP, ADP ATPlike, Allosteric 199 - 509 0 None D485G Bone morphogenetic protein receptor type-2 Homo sapiens

TKL_BMPR2 (Bone morphogenetic protein receptor type-2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism