7M0V

BRAF (Serine/threonine-protein kinase B-raf)
MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1)
Group: TKL STE
Uniprot: BRAF_HUMAN MP2K1_HUMAN
Organism: Homo sapiens
Domain boundary: 68 - 361 457 - 716
Resolution: 3.16

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens Inactive DFGin BLBplus out-out out-out ANP EUI Type1 Type3 42 - 383 0
A TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf Homo sapiens Inactive DFGin BLBplus out-out out-out ANP Type1 449 - 722 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       450        460        470        480 
gggrdssdDW EIPDGQITVG QRIGSGSFGT VYKGKWHGDV 
       490        500        510        520 
AVKMLNVTAP TPQQLQAFKN EVGVLRKTRH VNILLFMGYS 
       530        540        550        560 
TKPQLAIVTQ WCEGSSLYHH LHIIETKFEM IKLIDIARQT 
       570        580        590        600 
AQGMDYLHAK SIIHRDLKSN NIFLHEDLTV KIGDFGLATV 
       610        620        630        640 
KSRWSGSHQF EQLSGSILWM APEVIRMQDK NPYSFQSDVY 
       650        660        670        680 
AFGIVLYELM TGQLPYSNIN NRDQIIFMVG RGYLSPDLSK 
       690        700        710        720 
VRSNCPKAMK RLMAECLKKK RDERPLFPQI LASIELLARS 

LPk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None