| Chain id | Group | Gene | UniprotID | Protein | Organism | Activity | Spatial | Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B | STE | MAP2K1 | MP2K1_HUMAN | Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | 3EW ANP | Type3 Type1 | 42 - 383 | 0 |
| A | TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | ANP | Type1 | 448 - 721 | 0 |
Representative sequence - Chain A
450 460 470 480
gggrdssDDW EIPDGQITVG QRIGSGSFGT VYKGKWHGDV
490 500 510 520
AVKMLNVTAP TPQQLQAFKN EVGVLRKTRH VNILLFMGYS
530 540 550 560
TKPQLAIVTQ WCEGSSLYHH LHIIETKFEM IKLIDIARQT
570 580 590 600
AQGMDYLHAK SIIHRDLKSN NIFLHEDLTV KIGDFGLATV
610 620 630 640
KSRWSGSHQF EQLSGSILWM APEVIRMQDK NPYSFQSDVY
650 660 670 680
AFGIVLYELM TGQLPYSNIN NRDQIIFMVG RGYLSPDLSK
690 700 710 720
VRSNCPKAMK RLMAECLKKK RDERPLFPQI LASIELLARS
Lpk