Protein kinases in complex with 3EW (Selumetinib)

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLBplus 2 4U7ZA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U7ZA 2.805 Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0TB 3.19 Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1

Protein kinases in complex with 3EW

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLBplus 4 4U7ZA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U7ZA 2.805 Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0TB 3.19 Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUTC 3.09 Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUZC 3.21 Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3

Protein kinases in complex with 3EW

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLBplus 2 7JUZC
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUTC 3.09 Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUZC 3.21 Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3