6VN8

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in 3JW Type1 840 - 1132 0
B Inactive DFGin ABAminus in-in in-in 3JW Type1 843 - 1131 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -        844        854        864 
hhhhhhhhen lyfqgdptQF EERHLKFLQQ LGKGNFGSVE 
       874        884        894        904 
MCRYDPLQDN TGEVVAVKKL QHSTEEHLRD FEREIEILKS 
       914        924        934        944 
LQHDNIVKYK GVCYSAGRRN LKLIMEYLPY GSLRDYLQKH 
       954        964        974        984 
KERIDHIKLL QYTSQICKGM EYLGTKRYIH RDLATRNILV 
       994       1004       1014       1024 
ENENRVKIGD FGLTKVLPQD KEYYKVKEPG ESPIFWYAPE 
      1034       1044       1054       1064 
SLTESKFSVA SDVWSFGVVL YELFTYIEKS KSPPAEFMRM 
      1074       1084       1094       1104 
IGNDKQGQMI VFHLIELLKN NGRLPRPDGC PDEIYMIMTE 
      1114       1124 
CWNNNVNQRP SFRDLALRVD QIRDNMAg
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007