6WTO

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 1.74

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in 3JW Type1 843 - 1132 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       843        853        863        873 
mafedrdptQ FEERHLKFLQ QLGKGNFGSV EMCRYDPLqd 
       883        893        903        913 
nTGEVVAVKK LQHSTEEHLR DFEREIEILK SLQHDNIVKY 
       923        933        943        953 
KGVCYsagrr nLKLIMEYLP YGSLRDYLQK HKERIDHIKL 
       963        973        983        993 
LQYTSQICKG MEYLGTKRYI HRDLATRNIL VENENRVKIG 
      1003       1013       1023       1033 
DFGLTKVLPQ DKEYYKVKep geSPIFWYAP ESLTESKFSV 
      1043       1053       1063       1073 
ASDVWSFGVV LYELFTYIEK SKSPPAEFMR MIGNDKQGQM 
      1083       1093       1103       1113 
IVFHLIELLK NNGRLPRPDG CPDEIYMIMT ECWNNNVNQR 
      1123          - 
PSFRDLALRV DQIRDNMAGG Sgsenlyfq
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007,X1008