PDB: 5HVK — TKL LIMK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5HVKA
DFGin None 1 50.0% 5HVKC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1

PDB: 5HVK — TKL LIMK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5HVKA
DFGin None 1 50.0% 5HVKC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1 Homo sapiens

PDB: 5HVK — TKL LIMK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism