PDB: 5HVK — TKL LIMK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5HVKA
DFGin None 1 50.0% 5HVKC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LIMK1 LIMK1_HUMAN 5HVKA P53667 329 634 647.0 ANP:61001 ATPlike Active DFGin 6.4055 13.6462 BLAminus -145.46, 176.84 65.07, 82.49 -109.26, 24.73 304.62, 92.73 -71.79, -22.73 in-in in 7.7955 Saltbr-in 3.1595 HRD-in -70.8, -44.42 59.42, 18.52 in-in-in SNCiii in-in ActLoopNT-in 3.3239 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -139.63, 151.17 APE9-dihe-na 143.88, 171.7 APE8-dihe-in -71.51, 120.27 APE8-rot-na 199.31 APE67-dihe-in -66.59, -36.22 -54.03, -34.34 APE12-dist-in 9.3008 APE11-dist-in 11.0813 APE10-dist-in 5.6355 APE9-dist-in 3.574 D460N TPO508 TPO508 XRAY 3.5 0.275 0.31 A 315.0 293.0 13 42 29 13 [[339, 606]] 1.0 5hvk TKL_LIMK1_HUMAN TKL 3e-76 262.4 3.0 266.0 264.0 477 478 479 481 483 368 384 388 457 459 458 460.0 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKC P53667 329 633 647.0 ANP:60701 ATPlike Inactive DFGin 6.0783 13.9339 None -149.69, 172.69 -101.87, 169.41 -110.21, 23.25 306.34, 92.8 -73.91, -25.16 in-out in 7.8911 Saltbr-out 3.6442 HRD-in -72.39, -44.63 59.79, 17.6 out-in-in SNCoii in-in ActLoopNT-in 3.0698 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -140.53, 148.22 APE9-dihe-na 140.89, 172.08 APE8-dihe-in -72.12, 119.75 APE8-rot-na 199.66 APE67-dihe-in -64.48, -35.33 -54.5, -33.22 APE12-dist-in 8.6689 APE11-dist-in 11.1988 APE10-dist-in 5.8992 APE9-dist-in 3.5423 D460N TPO508 TPO508 XRAY 3.5 0.275 0.31 C 315.0 291.0 14 42 28 14 [[339, 606]] 1.0 5hvk TKL_LIMK1_HUMAN TKL 3e-76 262.4 3.0 266.0 264.0 477 478 479 481 483 368 384 388 457 459 458 460.0 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1

PDB: 5HVK — TKL LIMK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5HVKA
DFGin None 1 50.0% 5HVKC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL LIMK1 LIMK1_HUMAN 5HVKA P53667 329 634 647.0 ANP:61001 ATPlike Active DFGin 6.4055 13.6462 BLAminus -145.46, 176.84 65.07, 82.49 -109.26, 24.73 304.62, 92.73 -71.79, -22.73 in-in in 7.7955 Saltbr-in 3.1595 HRD-in -70.8, -44.42 59.42, 18.52 in-in-in SNCiii in-in ActLoopNT-in 3.3239 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -139.63, 151.17 APE9-dihe-na 143.88, 171.7 APE8-dihe-in -71.51, 120.27 APE8-rot-na 199.31 APE67-dihe-in -66.59, -36.22 -54.03, -34.34 APE12-dist-in 9.3008 APE11-dist-in 11.0813 APE10-dist-in 5.6355 APE9-dist-in 3.574 D460N TPO508 TPO508 XRAY 3.5 0.275 0.31 A 315.0 293.0 13 42 29 13 [[339, 606]] 1.0 5hvk Homo sapiens TKL_LIMK1_HUMAN TKL 3e-76 262.4 3.0 266.0 264.0 477 478 479 481 483 368 384 388 457 459 458 460.0 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKC P53667 329 633 647.0 ANP:60701 ATPlike Inactive DFGin 6.0783 13.9339 None -149.69, 172.69 -101.87, 169.41 -110.21, 23.25 306.34, 92.8 -73.91, -25.16 in-out in 7.8911 Saltbr-out 3.6442 HRD-in -72.39, -44.63 59.79, 17.6 out-in-in SNCoii in-in ActLoopNT-in 3.0698 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -140.53, 148.22 APE9-dihe-na 140.89, 172.08 APE8-dihe-in -72.12, 119.75 APE8-rot-na 199.66 APE67-dihe-in -64.48, -35.33 -54.5, -33.22 APE12-dist-in 8.6689 APE11-dist-in 11.1988 APE10-dist-in 5.8992 APE9-dist-in 3.5423 D460N TPO508 TPO508 XRAY 3.5 0.275 0.31 C 315.0 291.0 14 42 28 14 [[339, 606]] 1.0 5hvk Homo sapiens TKL_LIMK1_HUMAN TKL 3e-76 262.4 3.0 266.0 264.0 477 478 479 481 483 368 384 388 457 459 458 460.0 531 519 514 513 512 511 510 509 508 414 LIM domain kinase 1

PDB: 5HVK — TKL LIMK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name