Ligand: FI3

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4R5SA
DFGout BBAminus 1 50.0% 4R6VA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4R5SA P00533 697 1018 1210.0 FI3:1101 Type1.5_Back Inactive DFGin 5.101 14.574 BLAminus -157.2, -179.86 56.93, 47.29 -82.16, 60.06 358.48, 60.04 -65.03, -39.71 in-out in 9.457 Saltbr-out 4.992 HRD-in -64.01, -46.28 78.34, -4.7 out-in-out SNCoio in-out ActLoopNT-in 3.133 ActLoopCT-out TYR APEdihe_nnoao APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.94 APE8-dihe-out -63.79, -43.43 APE8-rot-na 31.31 APE67-dihe-out -60.79, -39.82 71.82, -57.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.805 L858R None None XRAY 3.001 0.209 0.239 A 331 299 9 0 0 9 [[712, 970]] 1.0 4r5s TYR_EGFR_HUMAN TYR 1.1e-86 296.4 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR FGFR4 FGFR4_HUMAN 4R6VA P22455 445 750 802.0 FI3:60801 Type1.5_Back Inactive DFGout 13.725 11.594 BBAminus -104.3, 160.0 -151.01, 100.96 -90.12, 14.65 307.32, 109.77 -121.7, 20.63 in-in in 7.979 Saltbr-in 2.852 HRD-in -75.49, -50.13 79.72, -18.12 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -44.34 APE8-rot-na 330.88 APE67-dihe-in -70.56, -4.7 -57.71, -39.53 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 V550L,R664E None None XRAY 2.353 0.179 0.227 A 323 271 35 0 0 17 [[467, 745]] 1.0 4r6v TYR_FGFR4_HUMAN TYR 3.3e-100 340.6 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: FI3

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4R5SA
DFGout BBAminus 1 50.0% 4R6VA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4R5SA P00533 697 1018 1210.0 FI3:1101 Type1.5_Back Inactive DFGin 5.101 14.574 BLAminus -157.2, -179.86 56.93, 47.29 -82.16, 60.06 358.48, 60.04 -65.03, -39.71 in-out in 9.457 Saltbr-out 4.992 HRD-in -64.01, -46.28 78.34, -4.7 out-in-out SNCoio in-out ActLoopNT-in 3.133 ActLoopCT-out TYR APEdihe_nnoao APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.94 APE8-dihe-out -63.79, -43.43 APE8-rot-na 31.31 APE67-dihe-out -60.79, -39.82 71.82, -57.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.805 L858R None None XRAY 3.001 0.209 0.239 A 331 299 9 0 0 9 [[712, 970]] 1.0 4r5s Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-86 296.4 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR FGFR4 FGFR4_HUMAN 4R6VA P22455 445 750 802.0 FI3:60801 Type1.5_Back Inactive DFGout 13.725 11.594 BBAminus -104.3, 160.0 -151.01, 100.96 -90.12, 14.65 307.32, 109.77 -121.7, 20.63 in-in in 7.979 Saltbr-in 2.852 HRD-in -75.49, -50.13 79.72, -18.12 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -44.34 APE8-rot-na 330.88 APE67-dihe-in -70.56, -4.7 -57.71, -39.53 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 V550L,R664E None None XRAY 2.353 0.179 0.227 A 323 271 35 0 0 17 [[467, 745]] 1.0 4r6v Homo sapiens TYR_FGFR4_HUMAN TYR 3.3e-100 340.6 1 261 261 629 630 631 633 635 503 520 524 609 611 610 612 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: FI3

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name