Ligand: EDD

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 3NNXA
DFGout None 1 50.0% 3NNWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 3NNXA Q16539 5 352 360.0 EDD:355 Type3 Inactive DFGout 14.2 9.2163 BBAminus -135.6, -177.89 -139.59, 108.47 -57.96, -45.51 273.61, 91.9 59.97, 25.47 in-in in 8.607 Saltbr-in 2.8874 HRD-in -71.36, -53.19 82.69, -16.33 in-out-out SNCioo out-out ActLoopNT-out 17.2369 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nioo APE10-dihe-na -88.62, 104.06 APE9-dihe-na -72.31, 123.14 APE8-dihe-out -62.65, -30.04 APE8-rot-out 108.29 APE67-dihe-in -62.69, -25.91 -61.93, -24.39 APE12-dist-none 999.0 APE11-dist-in 12.9915 APE10-dist-out 12.8716 APE9-dist-out 10.6831 None PTR182 PTR182 XRAY 2.28 0.222 0.285 A 354.0 337.0 11 25 18 7 [[24, 308]] 1.0 3nnx CMGC_MAPK14_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NNWA Q16539 4 352 360.0 EDD:355 Type2 Inactive DFGout 14.3784 8.6643 None -143.48, -174.31 -141.84, 103.66 -83.23, 17.1 235.42, 130.16 -65.05, 104.27 in-in in 8.6157 Saltbr-in 2.7512 HRD-in -70.41, -54.26 74.72, -13.01 in-out-out SNCioo out-out ActLoopNT-out 15.4752 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -136.01, 133.74 APE9-dihe-na -64.57, -21.86 APE8-dihe-out -56.02, -24.79 APE8-rot-out 60.58 APE67-dihe-in -62.38, -23.64 -112.3, -18.98 APE12-dist-out 19.8482 APE11-dist-out 21.0813 APE10-dist-out 15.5234 APE9-dist-out 11.7945 None None None XRAY 1.89 0.169 0.213 A 354.0 349.0 0 25 25 0 [[24, 308]] 1.0 3nnw CMGC_MAPK14_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: EDD

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 3NNXA
DFGout None 1 50.0% 3NNWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 3NNXA Q16539 5 352 360.0 EDD:355 Type3 Inactive DFGout 14.2 9.2163 BBAminus -135.6, -177.89 -139.59, 108.47 -57.96, -45.51 273.61, 91.9 59.97, 25.47 in-in in 8.607 Saltbr-in 2.8874 HRD-in -71.36, -53.19 82.69, -16.33 in-out-out SNCioo out-out ActLoopNT-out 17.2369 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nioo APE10-dihe-na -88.62, 104.06 APE9-dihe-na -72.31, 123.14 APE8-dihe-out -62.65, -30.04 APE8-rot-out 108.29 APE67-dihe-in -62.69, -25.91 -61.93, -24.39 APE12-dist-none 999.0 APE11-dist-in 12.9915 APE10-dist-out 12.8716 APE9-dist-out 10.6831 None PTR182 PTR182 XRAY 2.28 0.222 0.285 A 354.0 337.0 11 25 18 7 [[24, 308]] 1.0 3nnx Homo sapiens CMGC_MAPK14_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NNWA Q16539 4 352 360.0 EDD:355 Type2 Inactive DFGout 14.3784 8.6643 None -143.48, -174.31 -141.84, 103.66 -83.23, 17.1 235.42, 130.16 -65.05, 104.27 in-in in 8.6157 Saltbr-in 2.7512 HRD-in -70.41, -54.26 74.72, -13.01 in-out-out SNCioo out-out ActLoopNT-out 15.4752 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -136.01, 133.74 APE9-dihe-na -64.57, -21.86 APE8-dihe-out -56.02, -24.79 APE8-rot-out 60.58 APE67-dihe-in -62.38, -23.64 -112.3, -18.98 APE12-dist-out 19.8482 APE11-dist-out 21.0813 APE10-dist-out 15.5234 APE9-dist-out 11.7945 None None None XRAY 1.89 0.169 0.213 A 354.0 349.0 0 25 25 0 [[24, 308]] 1.0 3nnw Homo sapiens CMGC_MAPK14_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: EDD

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name