Ligand: C15

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 5 100.0% 6EQ9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 6EQ9A P53779 46 400 464.0 ACP:505,C15:506 ATPlike,Allosteric Inactive DFGin 3.763 14.1786 ABAminus -90.84, -25.71 -146.46, -174.02 -119.81, 8.04 305.39, 99.67 64.39, -162.69 in-out in 9.6534 Saltbr-out 3.9166 HRD-in -74.99, -56.85 72.96, -15.02 out-out-out SNCooo out-out ActLoopNT-out 6.2848 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -45.37 APE8-dihe-in -112.64, 106.03 APE8-rot-in 290.72 APE67-dihe-in -70.8, -9.5 -110.9, 2.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.5168 None None None XRAY 1.83 0.207 0.252 A 367.0 350.0 5 27 22 5 [[64, 359]] 1.0 6eq9 CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPA P53779 46 400 464.0 SWM:501,C15:512 Type1,Allosteric Inactive DFGin 3.9487 13.914 ABAminus -89.43, -27.22 -142.11, 175.41 -118.21, 7.54 305.21, 97.74 61.64, -136.69 in-none in 9.3247 Saltbr-none 999.0 HRD-in -70.92, -54.64 68.45, -3.99 none-out-out SNCnoo out-out ActLoopNT-out 5.6131 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_onno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 153.19 APE8-dihe-in -106.65, 112.81 APE8-rot-in 284.72 APE67-dihe-in -67.36, -13.74 -110.92, 6.88 APE12-dist-out 16.0093 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.8464 None None None XRAY 1.86 0.19 0.216 A 364.0 350.0 5 27 22 5 [[64, 359]] 1.0 8bzp CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHA P53779 46 400 464.0 BGE:504,C15:506 Type1,Allosteric Inactive DFGin 3.9296 14.0838 ABAminus -88.94, -22.23 -144.23, 173.35 -118.59, 4.36 304.38, 93.6 70.22, -170.04 in-in in 9.2242 Saltbr-in 2.9456 HRD-in -75.21, -57.6 72.31, -9.22 in-out-out SNCioo out-out ActLoopNT-out 6.35 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -72.6 APE8-dihe-in -99.06, 111.23 APE8-rot-in 304.28 APE67-dihe-in -64.51, -16.6 -105.92, -9.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.8429 None None None XRAY 1.76 999.0 999.0 A 367.0 344.0 11 27 22 5 [[64, 359]] 1.0 6emh CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHB P53779 46 400 464.0 BGE:502,C15:504 Type1,Allosteric Inactive DFGin 3.9838 13.9753 ABAminus -90.53, -23.08 -143.55, 174.7 -119.54, -1.04 302.02, 90.55 71.56, -172.09 in-in in 9.088 Saltbr-in 3.1394 HRD-in -71.43, -57.72 66.61, -12.51 in-out-out SNCioo out-out ActLoopNT-out 6.4686 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 150.41 APE8-dihe-in -92.15, 115.96 APE8-rot-in 304.13 APE67-dihe-in -65.86, -16.66 -109.13, -2.57 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.9796 None None None XRAY 1.76 999.0 999.0 B 367.0 344.0 11 27 22 5 [[64, 359]] 1.0 6emh CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPB P53779 47 400 464.0 SWM:502,C15:509,C15:510 Type1,Type1,Allosteric Inactive DFGin 3.8943 14.3724 ABAminus -88.61, -25.41 -141.39, 172.54 -107.56, 12.73 298.48, 92.43 76.94, -166.0 in-out in 9.4701 Saltbr-out 3.7104 HRD-in -75.07, -55.95 68.9, 0.04 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 128.71 APE8-rot-out 62.47 APE67-dihe-in -67.38, -8.49 -119.38, 11.72 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.86 0.19 0.216 B 364.0 326.0 19 27 12 15 [[64, 359]] 1.0 8bzp CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: C15

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 5 100.0% 6EQ9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 6EQ9A P53779 46 400 464.0 ACP:505,C15:506 ATPlike,Allosteric Inactive DFGin 3.763 14.1786 ABAminus -90.84, -25.71 -146.46, -174.02 -119.81, 8.04 305.39, 99.67 64.39, -162.69 in-out in 9.6534 Saltbr-out 3.9166 HRD-in -74.99, -56.85 72.96, -15.02 out-out-out SNCooo out-out ActLoopNT-out 6.2848 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -45.37 APE8-dihe-in -112.64, 106.03 APE8-rot-in 290.72 APE67-dihe-in -70.8, -9.5 -110.9, 2.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.5168 None None None XRAY 1.83 0.207 0.252 A 367.0 350.0 5 27 22 5 [[64, 359]] 1.0 6eq9 Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPA P53779 46 400 464.0 SWM:501,C15:512 Type1,Allosteric Inactive DFGin 3.9487 13.914 ABAminus -89.43, -27.22 -142.11, 175.41 -118.21, 7.54 305.21, 97.74 61.64, -136.69 in-none in 9.3247 Saltbr-none 999.0 HRD-in -70.92, -54.64 68.45, -3.99 none-out-out SNCnoo out-out ActLoopNT-out 5.6131 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_onno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 153.19 APE8-dihe-in -106.65, 112.81 APE8-rot-in 284.72 APE67-dihe-in -67.36, -13.74 -110.92, 6.88 APE12-dist-out 16.0093 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.8464 None None None XRAY 1.86 0.19 0.216 A 364.0 350.0 5 27 22 5 [[64, 359]] 1.0 8bzp Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHA P53779 46 400 464.0 BGE:504,C15:506 Type1,Allosteric Inactive DFGin 3.9296 14.0838 ABAminus -88.94, -22.23 -144.23, 173.35 -118.59, 4.36 304.38, 93.6 70.22, -170.04 in-in in 9.2242 Saltbr-in 2.9456 HRD-in -75.21, -57.6 72.31, -9.22 in-out-out SNCioo out-out ActLoopNT-out 6.35 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -72.6 APE8-dihe-in -99.06, 111.23 APE8-rot-in 304.28 APE67-dihe-in -64.51, -16.6 -105.92, -9.46 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.8429 None None None XRAY 1.76 999.0 999.0 A 367.0 344.0 11 27 22 5 [[64, 359]] 1.0 6emh Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHB P53779 46 400 464.0 BGE:502,C15:504 Type1,Allosteric Inactive DFGin 3.9838 13.9753 ABAminus -90.53, -23.08 -143.55, 174.7 -119.54, -1.04 302.02, 90.55 71.56, -172.09 in-in in 9.088 Saltbr-in 3.1394 HRD-in -71.43, -57.72 66.61, -12.51 in-out-out SNCioo out-out ActLoopNT-out 6.4686 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 150.41 APE8-dihe-in -92.15, 115.96 APE8-rot-in 304.13 APE67-dihe-in -65.86, -16.66 -109.13, -2.57 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.9796 None None None XRAY 1.76 999.0 999.0 B 367.0 344.0 11 27 22 5 [[64, 359]] 1.0 6emh Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.0 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPB P53779 47 400 464.0 SWM:502,C15:509,C15:510 Type1,Type1,Allosteric Inactive DFGin 3.8943 14.3724 ABAminus -88.61, -25.41 -141.39, 172.54 -107.56, 12.73 298.48, 92.43 76.94, -166.0 in-out in 9.4701 Saltbr-out 3.7104 HRD-in -75.07, -55.95 68.9, 0.04 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 128.71 APE8-rot-out 62.47 APE67-dihe-in -67.38, -8.49 -119.38, 11.72 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.86 0.19 0.216 B 364.0 326.0 19 27 12 15 [[64, 359]] 1.0 8bzp Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: C15

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name