Ligand: BMU

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 3 50.0% 3O8TA
DFGout BBAminus 2 33.3% 3O8UA
DFGin None 1 16.7% 3O8PA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK14 MK14_HUMAN 3O8PA 2.1 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnoo BMU Type1 5 - 351 0 None D168G Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3O8UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169Y Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3OBJA 2.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169R Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1KV1A 2.5 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3O8TA 2.0 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169A Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3OC1A 2.59 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169G Mitogen-activated protein kinase 14

Ligand: BMU

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 3 50.0% 3O8TA
DFGout BBAminus 2 33.3% 3O8UA
DFGin None 1 16.7% 3O8PA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_HUMAN 3O8PA 2.1 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnoo BMU Type1 5 - 351 0 None D168G Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3O8UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169Y Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3OBJA 2.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169R Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1KV1A 2.5 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3O8TA 2.0 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169A Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3OC1A 2.59 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169G Mitogen-activated protein kinase 14 Homo sapiens

Ligand: BMU

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism