CK1_VRK1 (Serine/threonine-protein kinase VRK1)

Total number of chains: 78
Active chains: 1
Uniprot: VRK1_HUMAN
Kinase Domain Residues: 37 - 326
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 76 97.4% AF-Q99986-K3A
DFGin None 2 2.6% 2KTYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q99986-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 29 - 334 0 None None Serine/threonine-protein kinase VRK1
6AC9A 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 342 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6AC9B 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6AC9C 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6AC9D 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
AF-Q99986-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 29 - 334 0 None None Serine/threonine-protein kinase VRK1
2LAVA 999.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 1 - 361 0 None None Serine/threonine-protein kinase VRK1
6BP0A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BP0C 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BRUA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BRUC 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BTWC 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BU6C 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CFMC 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CMMA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CMMC 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CQHC 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CSWA 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CSWC 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6DD4A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6DD4C 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VZHA 2.55 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VZHC 2.55 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
8V42A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
8V42C 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
2RSVA 999.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 1 - 396 0 None None Serine/threonine-protein kinase VRK1
5UKFA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 8E1 Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
5UKFB 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii 8E1 Type1 51 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
5UKFC 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi 8E1 Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
5UKFD 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8E1 Type1 39 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
3OP5A 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi REB Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
3OP5B 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi REB Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
3OP5C 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii REB Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
3OP5D 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oooi REB Type1 25 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
5UVFA 2.0 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
5UVFB 2.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BP0B 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E1D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BTWB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E8D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BU6B 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooi E8V Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BU6D 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E8V Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CMMB 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CMMD 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CNXA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi F87 Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CQHA 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi F8Y Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CQHB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F8Y Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CQHD 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F8Y Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CSWB 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FBY Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CSWD 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FBY Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6DD4B 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii G6J Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6DD4D 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii G6J Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VXUA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi RTJ Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VXUB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RTJ Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VXUD 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RTJ Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
8V42B 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii YD9 Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
8V42D 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii YD9 Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
5UVFC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 7DZ Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
5UVFD 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 7DZ Type1.5_Back 25 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BP0D 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E1D Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BRUB 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooi E5M Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BRUD 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E5M Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BTWA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8D Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BTWD 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E8D Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6BU6A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8V Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CFMA 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi EA7 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CFMB 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CFMD 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CNXB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CNXC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooi FCS Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6CNXD 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6NPNA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6NPNB 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6NPNC 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6NPND 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VXUC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi VBD Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VZHB 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi RYA Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
6VZHD 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RYA Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
2KTYA 999.0 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 1 - 360 0 None None Serine/threonine-protein kinase VRK1
2KULA 999.0 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 1 - 360 0 None None Serine/threonine-protein kinase VRK1

CK1_VRK1 (Serine/threonine-protein kinase VRK1)

Total number of chains: 78
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 76 97.4% AF-Q99986-K3A
DFGin None 2 2.6% 2KTYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
VRK1_HUMAN AF-Q99986-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 29 - 334 0 None None Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6AC9A 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 342 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6AC9B 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6AC9C 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6AC9D 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN AF-Q99986-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 29 - 334 0 None None Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 2LAVA 999.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 1 - 361 0 None None Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BP0A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BP0C 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BRUA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BRUC 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BTWC 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BU6C 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CFMC 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CMMA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CMMC 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CQHC 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CSWA 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CSWC 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6DD4A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6DD4C 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VZHA 2.55 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VZHC 2.55 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 8V42A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 8V42C 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 2RSVA 999.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 1 - 396 0 None None Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UKFA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 8E1 Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UKFB 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii 8E1 Type1 51 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UKFC 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi 8E1 Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UKFD 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8E1 Type1 39 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 3OP5A 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi REB Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 3OP5B 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi REB Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 3OP5C 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii REB Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 3OP5D 2.4 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oooi REB Type1 25 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UVFA 2.0 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UVFB 2.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BP0B 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E1D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BTWB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E8D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BU6B 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooi E8V Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BU6D 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E8V Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CMMB 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CMMD 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CNXA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi F87 Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CQHA 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi F8Y Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CQHB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F8Y Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CQHD 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F8Y Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CSWB 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FBY Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CSWD 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FBY Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6DD4B 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii G6J Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6DD4D 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii G6J Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VXUA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi RTJ Type1 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VXUB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RTJ Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VXUD 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RTJ Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 8V42B 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii YD9 Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 8V42D 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii YD9 Type1 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UVFC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 7DZ Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 5UVFD 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 7DZ Type1.5_Back 25 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BP0D 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E1D Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BRUB 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooi E5M Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BRUD 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E5M Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BTWA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8D Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BTWD 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E8D Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6BU6A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8V Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CFMA 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi EA7 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CFMB 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CFMD 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CNXB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CNXC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooi FCS Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6CNXD 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6NPNA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6NPNB 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6NPNC 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6NPND 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VXUC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi VBD Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VZHB 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi RYA Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 6VZHD 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RYA Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 2KTYA 999.0 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 1 - 360 0 None None Serine/threonine-protein kinase VRK1 Homo sapiens
VRK1_HUMAN 2KULA 999.0 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 1 - 360 0 None None Serine/threonine-protein kinase VRK1 Homo sapiens

CK1_VRK1 (Serine/threonine-protein kinase VRK1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism