5UKF

VRK1 (Serine/threonine-protein kinase VRK1)
Group: CK1
Uniprot: VRK1_HUMAN
Organism: Homo sapiens
Domain boundary: 37 - 326
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in 8E1 Type1 20 - 341 0
B None DFGin BLAminus in-none in-in 8E1 Type1 51 - 341 0
C None DFGin BLAminus in-none in-in 8E1 Type1 21 - 341 0
D Active DFGin BLAminus in-in in-in 8E1 Type1 39 - 341 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        11         21         31         41 
mrvkaaqagr qssakrhlae qfavgeiitd maaaawkVGL 
        51         61         71         81 
PigqggfgCI YLADmnsses vgsdapcVVK VepsdnGPLF 
        91        101        111        121 
TELKFYQRAA KPEQIQKWIR TRKLKYLGVP KYWGSGlhdk 
       131        141        151        161 
ngksyrFMIM DRFGSDLQKI YEANAKRFSR KTVLQLSLRI 
       171        181        191        201 
LDILEYIHEH EYVHGDIKAS NLLLNYKNPD QVYLVDYGLA 
       211        221        231        241 
YRYCPEGVHK AYAADPKRCH DGTIEFTSID AHNGVAPSRR 
       251        261        271        281 
GDLEILGYCM IQWLTGHLPW EDNLKDPKYV RDSKIRYREN 
       291        301        311        321 
IASLMDKCFP AANAPGEIAK YMETVKLLDY TEKPLYENLR 
       331        341        351        361 
DILLQGLKAI GSKDDGKLDL svvengglka ktitkkraae 

iee
Lower-case residues are disordered in structure.
Mutations: K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A
Phosphorylation: None