CK1_TTBK1 (Tau-tubulin kinase 1)

Total number of chains: 22
Active chains: 11
Uniprot: TTBK1_HUMAN
Kinase Domain Residues: 34 - 295
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 68.2% AF-Q5TCY1-K1A
DFGin ABAminus 7 31.8% 7Q8WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
4BTJA 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 21 - 312 0 None None Tau-tubulin kinase 1
4BTJB 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 21 - 313 0 None None Tau-tubulin kinase 1
AF-Q5TCY1-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 303 0 None None Tau-tubulin kinase 1
AF-Q5TCY1-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 303 0 None None Tau-tubulin kinase 1
4NFNA 1.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2KC Type1 22 - 314 0 None None Tau-tubulin kinase 1
7ZHNA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1
7ZHOA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQR Type1.5_Back 21 - 317 0 None None Tau-tubulin kinase 1
7ZHPA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQY Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1
7ZHQA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRD Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1
7JXXA 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 22 - 312 0 None None Tau-tubulin kinase 1
7JXYA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VSY Type1.5_Back 23 - 312 0 None None Tau-tubulin kinase 1
8XPZA 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 20 - 312 0 None None Tau-tubulin kinase 1
7QHWAAA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 313 0 None None Tau-tubulin kinase 1
7QHWCCC 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 312 0 None None Tau-tubulin kinase 1
7Q8VA 2.13 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 21 - 312 0 None None Tau-tubulin kinase 1
7Q8WA 2.02 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IO Type1 21 - 312 0 None None Tau-tubulin kinase 1
4BTMA 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 312 0 None None Tau-tubulin kinase 1
4BTMB 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 313 0 None None Tau-tubulin kinase 1
9HHWA 3.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1IU7 Type1 21 - 313 0 None None Tau-tubulin kinase 1
4BTKA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii DTQ Type1.5_Back 22 - 311 0 None None Tau-tubulin kinase 1
4NFMA 2.12 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 314 0 None None Tau-tubulin kinase 1
7JXYB 2.15 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_iini VSY Type1.5_Back 20 - 312 0 None None Tau-tubulin kinase 1

CK1_TTBK1 (Tau-tubulin kinase 1)

Total number of chains: 22
Active chains: 11
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 68.2% AF-Q5TCY1-K1A
DFGin ABAminus 7 31.8% 7Q8WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TTBK1_HUMAN 4BTJA 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 4BTJB 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN AF-Q5TCY1-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 303 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN AF-Q5TCY1-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 303 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 4NFNA 1.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2KC Type1 22 - 314 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7ZHNA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7ZHOA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQR Type1.5_Back 21 - 317 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7ZHPA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQY Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7ZHQA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRD Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7JXXA 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 22 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7JXYA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VSY Type1.5_Back 23 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 8XPZA 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 20 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7QHWAAA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7QHWCCC 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7Q8VA 2.13 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7Q8WA 2.02 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IO Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 4BTMA 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 4BTMB 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 9HHWA 3.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1IU7 Type1 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 4BTKA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii DTQ Type1.5_Back 22 - 311 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 4NFMA 2.12 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 314 0 None None Tau-tubulin kinase 1 Homo sapiens
TTBK1_HUMAN 7JXYB 2.15 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_iini VSY Type1.5_Back 20 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens

CK1_TTBK1 (Tau-tubulin kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism