STE_STK3 (Serine/threonine-protein kinase 3)

Total number of chains: 17
Active chains: 2
Uniprot: STK3_HUMAN
Kinase Domain Residues: 27 - 278
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 8 47.1% 4LGDA
DFGin BLAminus 5 29.4% AF-Q13188-K1A
DFGin ABAminus 1 5.9% 5DH3B
DFGin BLAplus 1 5.9% 6AO5A
DFGin None 1 5.9% 4LG4F
None None 1 5.9% 4LG4D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q13188-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 19 - 286 0 None None Serine/threonine-protein kinase 3
AF-Q13188-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 19 - 286 0 None None Serine/threonine-protein kinase 3
5DH3B 2.468 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5BS Type1 18 - 302 0 TPO174,TPO180 None Serine/threonine-protein kinase 3
8A66A 1.901 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 5BS Type1 24 - 303 0 TPO180 None Serine/threonine-protein kinase 3
8A66B 1.901 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 5BS Type1 18 - 304 0 TPO174,TPO180,TPO268 None Serine/threonine-protein kinase 3
5DH3A 2.468 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5BS Type1 19 - 307 0 TPO174,TPO180 None Serine/threonine-protein kinase 3
6AO5A 2.955 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioo APEdist_nooo ANP ATPlike 28 - 488 0 None D146N Serine/threonine-protein kinase 3
4LGDA 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 16 - 488 0 None D146N Serine/threonine-protein kinase 3
4LGDB 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 10 - 488 0 None D146N Serine/threonine-protein kinase 3
4LGDC 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 12 - 490 0 None D146N Serine/threonine-protein kinase 3
4LGDD 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 11 - 489 0 None D146N Serine/threonine-protein kinase 3
4LG4A 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3
4LG4B 2.42 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3
4LG4C 2.42 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 18 - 307 0 None D146N Serine/threonine-protein kinase 3
4LG4E 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3
4LG4F 2.42 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 18 - 310 0 None D146N Serine/threonine-protein kinase 3
4LG4D 2.42 Inactive None‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 26 - 308 0 None D146N Serine/threonine-protein kinase 3

STE_STK3 (Serine/threonine-protein kinase 3)

Total number of chains: 17
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 8 47.1% 4LGDA
DFGin BLAminus 5 29.4% AF-Q13188-K1A
DFGin ABAminus 1 5.9% 5DH3B
DFGin BLAplus 1 5.9% 6AO5A
DFGin None 1 5.9% 4LG4F
None None 1 5.9% 4LG4D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STK3_HUMAN AF-Q13188-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 19 - 286 0 None None Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN AF-Q13188-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 19 - 286 0 None None Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 5DH3B 2.468 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5BS Type1 18 - 302 0 TPO174,TPO180 None Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 8A66A 1.901 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 5BS Type1 24 - 303 0 TPO180 None Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 8A66B 1.901 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 5BS Type1 18 - 304 0 TPO174,TPO180,TPO268 None Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 5DH3A 2.468 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5BS Type1 19 - 307 0 TPO174,TPO180 None Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 6AO5A 2.955 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioo APEdist_nooo ANP ATPlike 28 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LGDA 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 16 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LGDB 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 10 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LGDC 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 12 - 490 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LGDD 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 11 - 489 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LG4A 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LG4B 2.42 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LG4C 2.42 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 18 - 307 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LG4E 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LG4F 2.42 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 18 - 310 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STK3_HUMAN 4LG4D 2.42 Inactive None‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 26 - 308 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens

STE_STK3 (Serine/threonine-protein kinase 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism