STE_STK26 (Serine/threonine-protein kinase 26)

Total number of chains: 9
Active chains: 2
Uniprot: STK26_HUMAN
Kinase Domain Residues: 24 - 274
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 22.2% AF-Q9P289-K1A
DFGin BLBminus 2 22.2% 7B36A
DFGin None 2 22.2% 3GGFA
DFGout None 2 22.2% 4FZAB
DFGinter None 1 11.1% 4FZFB

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9P289-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 282 0 None None Serine/threonine-protein kinase 26
AF-Q9P289-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 282 0 None None Serine/threonine-protein kinase 26
7B36C 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 59T Type1.5_Back 17 - 299 0 None None Serine/threonine-protein kinase 26
7B36A 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 59T Type1.5_Front 18 - 300 0 None None Serine/threonine-protein kinase 26
3GGFA 2.35 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_oooo GVD Type1 17 - 300 0 None None Serine/threonine-protein kinase 26
3GGFB 2.35 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_oooo GVD Type1 18 - 297 0 None None Serine/threonine-protein kinase 26
4FZFB 3.64 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioo DKI Type1 18 - 297 0 None D162A Serine/threonine-protein kinase 26
4FZAB 3.15 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 18 - 297 0 None D162A Serine/threonine-protein kinase 26
4FZDB 3.25 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 18 - 297 0 None D162A Serine/threonine-protein kinase 26

STE_STK26 (Serine/threonine-protein kinase 26)

Total number of chains: 9
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 22.2% AF-Q9P289-K1A
DFGin BLBminus 2 22.2% 7B36A
DFGin None 2 22.2% 3GGFA
DFGout None 2 22.2% 4FZAB
DFGinter None 1 11.1% 4FZFB

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STK26_HUMAN AF-Q9P289-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 282 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN AF-Q9P289-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 282 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN 7B36C 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 59T Type1.5_Back 17 - 299 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN 7B36A 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 59T Type1.5_Front 18 - 300 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN 3GGFA 2.35 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_oooo GVD Type1 17 - 300 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN 3GGFB 2.35 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_oooo GVD Type1 18 - 297 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN 4FZFB 3.64 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioo DKI Type1 18 - 297 0 None D162A Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN 4FZAB 3.15 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 18 - 297 0 None D162A Serine/threonine-protein kinase 26 Homo sapiens
STK26_HUMAN 4FZDB 3.25 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 18 - 297 0 None D162A Serine/threonine-protein kinase 26 Homo sapiens

STE_STK26 (Serine/threonine-protein kinase 26)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism