AGC_RPS6KA1-1 (Ribosomal protein S6 kinase alpha-1)

Total number of chains: 6
Active chains: 2
Uniprot: KS6A1_HUMAN
Kinase Domain Residues: 62 - 321
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 50.0% 2Z7RA
DFGin BLAminus 2 33.3% AF-Q15418-K1A
DFGin BLAplus 1 16.7% 8XOVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q15418-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 54 - 329 0 None None Ribosomal protein S6 kinase alpha-1
AF-Q15418-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 54 - 329 0 None None Ribosomal protein S6 kinase alpha-1
8XOVA 2.55 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo ANP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
2Z7QA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
2Z7RA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 53 - 340 0 None None Ribosomal protein S6 kinase alpha-1
2Z7SA 2.1 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno P01 Type1 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1

AGC_RPS6KA1-1 (Ribosomal protein S6 kinase alpha-1)

Total number of chains: 6
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 50.0% 2Z7RA
DFGin BLAminus 2 33.3% AF-Q15418-K1A
DFGin BLAplus 1 16.7% 8XOVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
KS6A1_HUMAN AF-Q15418-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 54 - 329 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
KS6A1_HUMAN AF-Q15418-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 54 - 329 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
KS6A1_HUMAN 8XOVA 2.55 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo ANP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
KS6A1_HUMAN 2Z7QA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
KS6A1_HUMAN 2Z7RA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 53 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
KS6A1_HUMAN 2Z7SA 2.1 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno P01 Type1 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens

AGC_RPS6KA1-1 (Ribosomal protein S6 kinase alpha-1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism