TYR_MET (Hepatocyte growth factor receptor)

Total number of chains: 126
Active chains: 2
Family: TYR
Uniprot: MET_HUMAN
Kinase Domain Residues: 1076 - 1339
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 75 59.5% 3DKCA
DFGout BBAminus 31 24.6% 8OUUB
DFGout None 7 5.6% 3RHKA
None None 4 3.2% 3EFJB
DFGin ABAminus 3 2.4% 3Q6WA
DFGin BLAminus 2 1.6% AF-P08581-K1A
DFGin None 2 1.6% 3EFKA
DFGin BLBminus 1 0.8% 3Q6UA
DFGin BLBtrans 1 0.8% 5HLWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-P08581-K1A 1068 1347 1390.0 No_ligand No_ligand Active DFGin 6.61 14.387 BLAminus -141.76, -176.05 55.59, 75.76 -89.46, 14.38 301.99, 115.12 -58.79, -29.71 in-in in 8.321 Saltbr-in 2.676 HRD-in -73.97, -41.75 66.87, -17.49 in-in-in SNCiii in-in ActLoopNT-in 3.27 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.23, 99.49 APE9-dihe-in -81.99, 148.85 APE8-dihe-in -79.26, 65.28 APE8-rot-na 37.58 APE67-dihe-in -73.73, -13.28 -44.92, -39.54 APE12-dist-na 12.49 APE11-dist-na 7.881 APE10-dist-na 10.604 APE9-dist-in 6.706 None None None AF2 -1.0 1.0 1.0 A 280 280 0 0 0 0 [[1078, 1339]] 1.0 AF-P08581-K1 TYR_MET_HUMAN TYR 4.8e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
AF-P08581-K3A 1068 1347 1390.0 No_ligand No_ligand Active DFGin 6.29 14.454 BLAminus -144.17, -175.7 57.67, 71.22 -86.62, 14.75 300.5, 104.92 -59.08, -33.54 in-in in 8.552 Saltbr-in 2.682 HRD-in -80.38, -43.65 66.25, -13.46 in-in-in SNCiii in-in ActLoopNT-in 2.893 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.57, 87.82 APE9-dihe-in -84.23, 145.95 APE8-dihe-in -81.54, 62.86 APE8-rot-na 37.83 APE67-dihe-in -72.05, -14.12 -45.52, -36.53 APE12-dist-na 12.513 APE11-dist-na 8.566 APE10-dist-na 9.904 APE9-dist-in 6.223 None None None AF2 -1.0 1.0 1.0 A 280 280 0 0 0 0 [[1078, 1339]] 1.0 AF-P08581-K3 TYR_MET_HUMAN TYR 4.8e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4IWDA 1048 1348 1390.0 AME:50001,1JC:61401 Allosteric,Type1 Inactive DFGin 6.543 14.301 ABAminus -108.09, -32.72 -101.39, 130.91 -125.93, 29.16 298.42, 93.31 -62.5, -20.72 in-in in 7.543 Saltbr-in 2.682 HRD-in -68.72, -51.93 72.01, -13.84 in-in-none SNCiin in-none ActLoopNT-in 2.864 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -44.03 APE9-dihe-in -64.62, 131.07 APE8-dihe-in -85.04, 84.89 APE8-rot-na 35.71 APE67-dihe-in -69.34, -7.33 -42.52, -52.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 7.704 APE9-dist-in 6.106 None PTR1234,PTR1235 PTR1234,PTR1235 XRAY 1.99 0.207 0.257 A 306 297 4 0 0 4 [[1078, 1339]] 1.0 4iwd TYR_MET_HUMAN TYR 6.7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3Q6WA 1050 1348 1390.0 Q6W:60001 Type1 Inactive DFGin 6.557 14.212 ABAminus -113.39, -31.38 -103.35, 133.16 -129.6, 28.19 294.61, 91.16 -57.03, -25.46 in-in in 7.727 Saltbr-in 2.744 HRD-in -76.23, -49.43 72.94, -9.8 in-in-none SNCiin in-none ActLoopNT-in 2.828 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 20.1 APE9-dihe-in -70.96, 140.5 APE8-dihe-in -77.07, 74.54 APE8-rot-na 32.13 APE67-dihe-in -73.0, -2.61 -44.68, -48.59 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.073 APE9-dist-in 6.837 None PTR1234,PTR1235 PTR1234,PTR1235 XRAY 1.75 0.205 0.227 A 307 295 4 0 0 4 [[1078, 1339]] 1.0 3q6w TYR_MET_HUMAN TYR 6.8e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3R7OA 1048 1348 1390.0 M61:60001 Type1 Inactive DFGin 6.538 14.144 ABAminus -102.5, -37.51 -98.26, 136.29 -130.03, 25.37 293.68, 92.54 -51.9, -36.59 in-in in 8.523 Saltbr-in 2.796 HRD-in -64.86, -55.72 73.4, -5.55 in-in-none SNCiin in-none ActLoopNT-in 3.08 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 3.86 APE9-dihe-in -59.13, 149.03 APE8-dihe-in -86.97, 92.69 APE8-rot-na 29.75 APE67-dihe-in -64.62, -7.75 -51.29, -49.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 9.929 APE9-dist-in 6.448 None PTR1234,PTR1235 PTR1234,PTR1235 XRAY 2.3 0.213 0.24 A 307 297 4 0 0 4 [[1078, 1339]] 1.0 3r7o TYR_MET_HUMAN TYR 6.8e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3Q6UA 1048 1348 1390.0 AME:50001 Allosteric Inactive DFGin 5.3 15.171 BLBminus -141.8, -165.83 43.31, 48.52 -52.58, 142.95 318.65, 93.03 -67.63, 999.0 in-out in 8.567 Saltbr-out 5.754 HRD-in -70.18, -46.51 72.44, -16.24 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -18.53 APE8-dihe-in -77.28, 65.76 APE8-rot-na 29.07 APE67-dihe-in -73.85, -1.6 -47.31, -44.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.898 None None None XRAY 1.6 0.185 0.214 A 308 281 20 0 0 20 [[1078, 1339]] 1.0 3q6u TYR_MET_HUMAN TYR 6.8e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3DKCA 1051 1360 1390.0 ATP:60001 ATPlike Inactive DFGin 5.693 13.103 BLBplus -128.11, 162.74 67.51, 17.44 -61.67, 130.17 44.2, 92.69 80.08, -22.94 out-out out 14.083 Saltbr-out 12.836 HRD-in -71.17, -57.45 82.5, -22.81 out-out-out SNCooo out-out ActLoopNT-out 7.739 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -83.24, -9.16 APE9-dihe-in -104.14, 150.23 APE8-dihe-in -75.82, 62.17 APE8-rot-na 30.64 APE67-dihe-in -64.7, -18.65 -61.74, -26.11 APE12-dist-na 18.53 APE11-dist-na 20.199 APE10-dist-na 15.662 APE9-dist-out 9.072 Y1194F,Y1234F,Y1235D None None XRAY 1.52 0.189 0.218 A 317 310 0 0 0 0 [[1078, 1339]] 1.0 3dkc TYR_MET_HUMAN TYR 8.6e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
2G15A 1046 1346 1390.0 No_ligand No_ligand Inactive DFGin 5.308 14.807 BLBplus -126.95, -156.89 55.44, 45.38 -146.85, 161.09 77.95, 91.4 56.77, -133.56 out-out out 12.828 Saltbr-out 9.792 HRD-in -76.71, -50.46 77.7, -17.49 out-out-in SNCooi out-in ActLoopNT-out 10.595 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.17, 130.97 APE9-dihe-in -100.06, 147.13 APE8-dihe-in -78.36, 70.19 APE8-rot-na 37.37 APE67-dihe-in -76.51, 3.63 -46.75, -47.03 APE12-dist-na 19.695 APE11-dist-na 15.425 APE10-dist-na 18.424 APE9-dist-in 7.346 None None None XRAY 2.15 0.234 0.259 A 318 301 0 0 0 0 [[1078, 1339]] 1.0 2g15 TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
1R1WA 1050 1360 1390.0 No_ligand No_ligand Inactive DFGin 6.39 14.656 BLBplus -130.27, -160.33 52.67, 47.82 -146.19, 163.95 73.82, 94.67 55.34, -136.67 out-out out 13.083 Saltbr-out 8.828 HRD-in -65.43, -49.53 76.09, -18.82 out-out-none SNCoon out-none ActLoopNT-out 11.48 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 149.17 APE8-dihe-in -80.54, 64.23 APE8-rot-na 34.06 APE67-dihe-in -75.31, -10.28 -59.25, -30.26 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.438 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 1.8 0.174 0.204 A 312 287 24 0 0 14 [[1078, 1339]] 1.0 1r1w TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8AU3A 1052 1349 1390.0 3E8:1401 Type1 Inactive DFGin 5.684 14.29 BLBplus -124.89, -160.9 56.91, 51.79 -144.24, 164.35 65.96, 84.2 62.67, -127.3 out-out out 12.107 Saltbr-out 10.728 HRD-in -74.56, -50.99 74.86, 1.96 out-out-out SNCooo out-out ActLoopNT-out 10.759 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -67.06 APE8-dihe-out -64.75, -14.77 APE8-rot-na 35.69 APE67-dihe-in -73.18, -9.04 -40.0, -46.69 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 10.271 Y1234E,Y1235E None None XRAY 2.26 0.198 0.24 A 299 285 13 0 0 13 [[1078, 1339]] 1.0 8au3 TYR_MET_HUMAN TYR 4.5e-91 310.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8AU3B 1056 1349 1390.0 3E8:1401 Type1 Inactive DFGin 5.496 14.473 BLBplus -125.67, -163.77 56.96, 51.67 -147.0, 169.32 67.61, 95.69 59.55, -126.73 out-out out 15.391 Saltbr-out 16.785 HRD-in -71.6, -51.19 76.55, 0.05 out-out-out SNCooo out-out ActLoopNT-out 10.966 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -66.77 APE8-dihe-out -65.4, -13.15 APE8-rot-na 35.16 APE67-dihe-in -76.94, -3.51 -35.23, -49.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 10.331 Y1234E,Y1235E None None XRAY 2.26 0.198 0.24 B 299 281 13 0 0 13 [[1078, 1339]] 1.0 8au3 TYR_MET_HUMAN TYR 4.5e-91 310.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8AU5A 1067 1346 1390.0 3E8:1401 Type1 Inactive DFGin 5.707 14.374 BLBplus -119.33, -165.19 60.98, 56.2 -152.49, 146.81 74.85, 101.87 68.18, -123.4 out-out out 15.336 Saltbr-out 11.537 HRD-in -65.68, -49.98 78.74, -13.11 out-out-in SNCooi out-in ActLoopNT-out 10.8 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.2, 134.11 APE9-dihe-in -112.02, 144.15 APE8-dihe-in -87.51, 76.24 APE8-rot-na 34.54 APE67-dihe-in -68.65, -16.74 -55.51, -46.08 APE12-dist-na 20.917 APE11-dist-na 16.445 APE10-dist-na 17.773 APE9-dist-in 7.409 F1200I None None XRAY 2.72 0.239 0.278 A 299 265 15 0 0 2 [[1078, 1339]] 1.0 8au5 TYR_MET_HUMAN TYR 1.6e-91 312.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8AW1A 1066 1345 1390.0 3E8:1401 Type1 Inactive DFGin 5.295 13.933 BLBplus -124.71, -163.84 60.77, 51.89 -150.77, 158.45 69.7, 88.83 60.72, -129.97 out-out out 14.414 Saltbr-out 12.19 HRD-in -71.16, -55.41 80.21, -13.77 out-out-none SNCoon out-none ActLoopNT-out 10.771 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 138.91 APE9-dihe-in -126.21, 148.9 APE8-dihe-in -85.84, 71.21 APE8-rot-na 27.14 APE67-dihe-in -72.93, -13.12 -55.01, -33.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 18.233 APE9-dist-in 7.208 Y1235D None None XRAY 2.14 0.218 0.241 A 299 263 17 0 0 8 [[1078, 1339]] 1.0 8aw1 TYR_MET_HUMAN TYR 3.4e-91 311.1 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8AW1B 1064 1345 1390.0 3E8:1401 Type1 Inactive DFGin 5.302 14.15 BLBplus -123.92, -163.21 58.0, 49.54 -149.17, 156.39 75.23, 94.55 65.41, -133.45 out-out out 14.898 Saltbr-out 12.507 HRD-in -69.21, -52.41 76.89, -7.96 out-out-in SNCooi out-in ActLoopNT-out 10.535 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.96, 136.97 APE9-dihe-in -126.46, 148.09 APE8-dihe-in -85.21, 69.6 APE8-rot-na 28.63 APE67-dihe-in -72.96, -12.49 -53.88, -33.35 APE12-dist-na 999.0 APE11-dist-na 18.063 APE10-dist-na 18.136 APE9-dist-in 7.261 Y1235D None None XRAY 2.14 0.218 0.241 B 299 264 18 0 0 8 [[1078, 1339]] 1.0 8aw1 TYR_MET_HUMAN TYR 3.4e-91 311.1 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4KNBA 1064 1344 1390.0 1RU:1401 Type1 Inactive DFGin 7.396 15.201 BLBplus -152.82, -179.39 62.03, 58.92 -149.54, 152.74 61.81, 86.02 75.53, -138.63 out-out out 14.197 Saltbr-out 10.579 HRD-in -69.86, -46.71 77.62, -9.35 out-out-in SNCooi out-in ActLoopNT-out 10.903 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.7, 119.58 APE9-dihe-in -122.47, 151.86 APE8-dihe-in -86.64, 71.14 APE8-rot-na 34.49 APE67-dihe-in -76.94, -9.0 -56.56, -34.11 APE12-dist-na 20.969 APE11-dist-na 17.384 APE10-dist-na 17.285 APE9-dist-in 7.257 None None None XRAY 2.4 0.241 0.288 A 287 273 8 0 0 0 [[1078, 1339]] 1.0 4knb TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4KNBB 1067 1346 1390.0 1RU:1401 Type1 Inactive DFGin 6.633 14.923 BLBplus -140.56, -158.55 49.94, 50.72 -140.14, 167.67 69.36, 88.3 68.61, -122.44 out-out out 12.979 Saltbr-out 11.834 HRD-in -70.12, -52.42 79.03, -19.75 out-out-none SNCoon out-none ActLoopNT-out 10.575 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.8 APE8-dihe-in -88.71, 82.26 APE8-rot-na 34.66 APE67-dihe-in -82.92, -0.08 -66.31, -34.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.226 None None None XRAY 2.4 0.241 0.288 B 287 256 24 0 0 7 [[1078, 1339]] 1.0 4knb TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4KNBC 1060 1346 1390.0 1RU:1401 Type1 Inactive DFGin 7.512 15.058 BLBplus -156.58, -177.82 66.97, 40.82 -135.01, 151.51 62.44, 86.93 79.96, -136.08 out-out out 14.073 Saltbr-out 12.236 HRD-in -72.87, -52.33 81.95, -23.66 out-out-in SNCooi out-in ActLoopNT-out 10.826 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -91.48, 116.68 APE9-dihe-in -120.39, 142.28 APE8-dihe-in -82.11, 77.71 APE8-rot-na 33.0 APE67-dihe-in -75.83, -4.77 -60.57, -35.58 APE12-dist-na 20.424 APE11-dist-na 16.911 APE10-dist-na 16.769 APE9-dist-in 7.267 None None None XRAY 2.4 0.241 0.288 C 287 271 16 0 0 2 [[1078, 1339]] 1.0 4knb TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4KNBD 1064 1346 1390.0 1RU:1401 Type1 Inactive DFGin 6.986 14.712 BLBplus -149.29, -177.18 65.69, 42.15 -130.43, 146.51 58.33, 85.64 71.37, -113.33 out-out out 13.073 Saltbr-out 11.475 HRD-in -71.74, -48.48 75.48, -1.19 out-out-none SNCoon out-none ActLoopNT-out 10.032 ActLoopCT-none TYR APEdihe_nnnan APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-na 999.0 APE67-dihe-none -71.11, -17.0 999.0, -33.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.241 0.288 D 287 247 36 0 0 17 [[1078, 1339]] 1.0 4knb TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4R1VA 1055 1345 1390.0 3E8:1401 Type1 Inactive DFGin 6.851 15.131 BLBplus -128.85, -160.46 55.61, 46.43 -145.43, 164.26 73.06, 94.72 59.68, -132.26 out-out out 13.914 Saltbr-out 11.075 HRD-in -72.84, -48.56 75.96, -10.9 out-out-in SNCooi out-in ActLoopNT-out 10.449 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.25, 114.51 APE9-dihe-in -113.76, 127.94 APE8-dihe-in -81.67, 70.95 APE8-rot-na 30.91 APE67-dihe-in -76.37, -2.92 -53.11, -41.22 APE12-dist-na 20.098 APE11-dist-na 17.696 APE10-dist-na 15.864 APE9-dist-in 7.088 None None None XRAY 1.2 0.146 0.176 A 291 289 2 0 0 0 [[1078, 1339]] 1.0 4r1v TYR_MET_HUMAN TYR 5.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
2WD1A 1055 1346 1390.0 ZZY:2347 Type1 Inactive DFGin 6.715 15.354 BLBplus -130.22, -166.88 64.65, 49.75 -149.56, 164.94 68.51, 95.8 63.64, -135.28 out-out out 13.824 Saltbr-out 12.347 HRD-in -74.73, -45.22 71.7, -7.55 out-out-in SNCooi out-in ActLoopNT-out 10.742 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.57, 113.21 APE9-dihe-in -115.76, 119.45 APE8-dihe-in -78.13, 71.2 APE8-rot-na 32.53 APE67-dihe-in -78.85, -3.09 -55.46, -34.61 APE12-dist-na 20.5 APE11-dist-na 17.629 APE10-dist-na 15.642 APE9-dist-in 7.141 None None None XRAY 2.0 0.212 0.265 A 292 289 3 0 0 0 [[1078, 1339]] 1.0 2wd1 TYR_MET_HUMAN TYR 5.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4R1YA 1062 1346 1390.0 3EH:1401 Type1 Inactive DFGin 5.389 14.32 BLBplus -132.11, -159.52 51.31, 47.36 -144.5, 163.73 73.25, 87.93 64.4, -132.62 out-out out 15.877 Saltbr-out 12.711 HRD-in -64.58, -54.45 81.56, -8.87 out-out-in SNCooi out-in ActLoopNT-out 10.511 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.36, 113.99 APE9-dihe-in -111.97, 135.44 APE8-dihe-in -80.5, 71.16 APE8-rot-na 34.01 APE67-dihe-in -79.68, -2.29 -56.23, -33.98 APE12-dist-na 20.296 APE11-dist-na 17.153 APE10-dist-na 16.547 APE9-dist-in 7.184 None None None XRAY 2.0 0.182 0.238 A 292 265 20 0 0 2 [[1078, 1339]] 1.0 4r1y TYR_MET_HUMAN TYR 5.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3F66A 1052 1349 1390.0 IHX:1 Type1 Inactive DFGin 7.263 14.857 BLBplus -128.75, -158.89 48.95, 46.34 -144.78, 166.08 75.55, 97.31 63.29, -132.51 out-out out 13.574 Saltbr-out 11.349 HRD-in -64.61, -55.36 78.27, -14.18 out-out-in SNCooi out-in ActLoopNT-out 10.594 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.3, 122.4 APE9-dihe-in -117.84, 131.22 APE8-dihe-in -81.93, 72.25 APE8-rot-na 30.12 APE67-dihe-in -81.86, -2.13 -59.58, -32.42 APE12-dist-na 999.0 APE11-dist-na 19.318 APE10-dist-na 17.265 APE9-dist-in 7.512 None None None XRAY 1.4 0.168 0.225 A 298 288 10 0 0 5 [[1078, 1339]] 1.0 3f66 TYR_MET_HUMAN TYR 6.1e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3F66B 1062 1349 1390.0 IHX:2 Type1 Inactive DFGin 6.17 14.857 BLBplus -124.32, -152.82 48.56, 45.67 -143.8, 164.53 77.46, 95.64 58.79, -132.52 out-out out 12.635 Saltbr-out 10.008 HRD-in -70.66, -50.0 82.15, -19.93 out-out-in SNCooi out-in ActLoopNT-out 10.506 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.09, 122.26 APE9-dihe-in -125.33, 130.32 APE8-dihe-in -82.56, 66.62 APE8-rot-na 32.5 APE67-dihe-in -73.35, -5.99 -57.96, -33.87 APE12-dist-na 999.0 APE11-dist-na 18.786 APE10-dist-na 16.529 APE9-dist-in 7.5 None None None XRAY 1.4 0.168 0.225 B 298 269 19 0 0 6 [[1078, 1339]] 1.0 3f66 TYR_MET_HUMAN TYR 6.1e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B3QA 1055 1344 1390.0 SV5:1401 Type1 Inactive DFGin 6.832 15.773 BLBplus -131.15, -158.97 56.06, 42.1 -142.47, 159.33 72.23, 89.52 55.71, -134.93 out-out out 13.378 Saltbr-out 11.858 HRD-in -71.71, -52.43 80.21, -12.26 out-out-none SNCoon out-none ActLoopNT-out 11.132 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 59.63 APE8-rot-na 31.05 APE67-dihe-in -75.78, -2.08 -59.63, -33.45 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.75 0.172 0.192 A 299 283 7 0 0 7 [[1078, 1339]] 1.0 7b3q TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B3TA 1062 1344 1390.0 SVK:1401 Type1 Inactive DFGin 6.519 15.327 BLBplus -120.02, -162.4 55.57, 41.79 -137.77, 159.0 68.39, 89.6 58.57, -125.45 out-none out 13.689 Saltbr-none 999.0 HRD-in -66.03, -59.34 82.42, -20.25 none-out-none SNCnon out-none ActLoopNT-out 10.981 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.08 APE8-dihe-in -83.51, 64.45 APE8-rot-na 32.74 APE67-dihe-in -77.89, -3.69 -51.47, -31.87 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.364 None None None XRAY 2.23 0.213 0.261 A 299 261 22 0 0 8 [[1078, 1339]] 1.0 7b3t TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B3VA 1057 1344 1390.0 SWB:1401 Type1 Inactive DFGin 6.716 15.052 BLBplus -126.23, -152.04 48.88, 44.58 -143.57, 160.23 70.62, 87.46 59.4, -135.97 out-out out 12.514 Saltbr-out 11.795 HRD-in -62.92, -51.88 77.76, -15.35 out-out-none SNCoon out-none ActLoopNT-out 11.439 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 136.89 APE8-dihe-in -89.06, 65.51 APE8-rot-na 32.11 APE67-dihe-in -77.53, -1.68 -55.38, -33.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.586 None None None XRAY 1.93 0.226 0.248 A 299 274 14 0 0 14 [[1078, 1339]] 1.0 7b3v TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B3WA 1067 1344 1390.0 SVH:1402 Type1 Inactive DFGin 5.387 13.871 BLBplus -131.54, -154.8 46.8, 51.05 -143.29, 166.34 73.88, 93.09 55.12, -131.3 none-none none 999.0 Saltbr-none 999.0 HRD-in -71.86, -48.55 76.55, -13.24 none-out-in SNCnoi out-in ActLoopNT-out 10.691 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.57, 125.95 APE9-dihe-in -121.38, 106.22 APE8-dihe-in -80.21, 79.23 APE8-rot-na 27.53 APE67-dihe-in -82.98, -4.93 -45.47, -41.85 APE12-dist-na 17.77 APE11-dist-na 16.633 APE10-dist-na 14.553 APE9-dist-in 6.661 None None None XRAY 2.02 0.234 0.261 A 299 259 19 0 0 0 [[1078, 1339]] 1.0 7b3w TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B3ZA 1055 1344 1390.0 SV8:1402 Type1 Inactive DFGin 6.58 14.893 BLBplus -126.68, -152.67 54.96, 44.35 -145.25, 158.18 71.33, 93.43 60.81, -133.47 out-out out 12.488 Saltbr-out 9.584 HRD-in -68.18, -50.86 78.29, -16.82 out-out-none SNCoon out-none ActLoopNT-out 11.274 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 56.56 APE8-rot-na 31.04 APE67-dihe-in -77.58, -5.34 -58.45, -27.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.8 0.194 0.215 A 299 277 13 0 0 10 [[1078, 1339]] 1.0 7b3z TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B40A 1055 1346 1390.0 SWN:1401 Type1 Inactive DFGin 6.79 14.911 BLBplus -121.15, -157.08 57.45, 51.11 -151.5, 157.52 69.47, 91.73 61.68, -131.87 out-out out 12.671 Saltbr-out 10.542 HRD-in -64.67, -50.63 76.39, -16.73 out-out-none SNCoon out-none ActLoopNT-out 11.24 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 55.67 APE8-rot-na 31.0 APE67-dihe-in -75.78, 0.12 -57.64, -33.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.76 0.198 0.232 A 299 279 13 0 0 10 [[1078, 1339]] 1.0 7b40 TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B41A 1055 1346 1390.0 SWK:1401 Type1 Inactive DFGin 6.436 15.448 BLBplus -124.18, -158.65 59.39, 42.13 -146.22, 161.88 71.86, 91.85 59.6, -131.08 out-out out 13.229 Saltbr-out 12.226 HRD-in -68.34, -50.78 73.99, -12.52 out-out-none SNCoon out-none ActLoopNT-out 11.136 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.12 APE8-dihe-in -81.62, 71.84 APE8-rot-na 32.68 APE67-dihe-in -74.71, -7.29 -62.43, -28.21 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.609 None None None XRAY 1.97 0.198 0.233 A 299 281 11 0 0 8 [[1078, 1339]] 1.0 7b41 TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B42A 1055 1344 1390.0 SW8:1401 Type1 Inactive DFGin 6.437 15.377 BLBplus -131.8, -155.43 53.21, 43.89 -142.75, 162.05 73.24, 92.06 57.88, -128.49 out-out out 13.148 Saltbr-out 9.811 HRD-in -67.34, -48.52 73.85, -12.1 out-out-none SNCoon out-none ActLoopNT-out 11.133 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.12 APE8-dihe-in -83.17, 71.94 APE8-rot-na 32.5 APE67-dihe-in -76.0, -4.88 -61.93, -28.32 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.478 None None None XRAY 1.8 0.203 0.225 A 299 279 11 0 0 8 [[1078, 1339]] 1.0 7b42 TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B43A 1055 1344 1390.0 SW5:1401 Type1 Inactive DFGin 6.725 15.384 BLBplus -126.09, -157.56 60.31, 47.69 -153.83, 159.32 70.69, 88.14 59.9, -130.71 out-out out 12.692 Saltbr-out 10.243 HRD-in -65.42, -49.31 73.61, -13.55 out-out-none SNCoon out-none ActLoopNT-out 11.15 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 60.98 APE8-rot-na 29.69 APE67-dihe-in -76.44, -8.08 -59.13, -26.96 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.87 0.203 0.248 A 299 277 13 0 0 10 [[1078, 1339]] 1.0 7b43 TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B43B 1055 1346 1390.0 SW5:1401 Type1 Inactive DFGin 6.236 15.323 BLBplus -125.04, -160.72 66.1, 34.55 -135.49, 162.98 72.55, 100.65 59.58, -127.12 out-out out 12.988 Saltbr-out 10.686 HRD-in -68.52, -55.71 82.35, -23.91 out-out-none SNCoon out-none ActLoopNT-out 11.179 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 39.26 APE8-rot-na 32.26 APE67-dihe-in -72.77, -5.06 -51.67, -38.14 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.87 0.203 0.248 B 299 278 14 0 0 10 [[1078, 1339]] 1.0 7b43 TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7B44A 1055 1346 1390.0 SVT:1401 Type1 Inactive DFGin 7.175 15.058 BLBplus -129.18, -161.23 56.95, 43.1 -145.51, 165.59 71.68, 95.88 55.78, -129.36 out-out out 12.739 Saltbr-out 10.066 HRD-in -67.86, -52.32 77.82, -15.46 out-out-none SNCoon out-none ActLoopNT-out 11.011 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 53.85 APE8-rot-na 33.36 APE67-dihe-in -75.94, -5.45 -57.41, -32.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.76 0.18 0.208 A 299 282 10 0 0 7 [[1078, 1339]] 1.0 7b44 TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
2WGJA 1052 1345 1390.0 VGH:2346 Type1 Inactive DFGin 5.419 14.21 BLBplus -135.65, -156.26 47.26, 45.25 -135.61, 161.65 71.89, 90.85 65.05, -128.27 out-out out 14.431 Saltbr-out 12.345 HRD-in -73.92, -55.59 85.56, -13.18 out-out-in SNCooi out-in ActLoopNT-out 10.89 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -55.61, 121.54 APE9-dihe-in -139.09, 151.01 APE8-dihe-in -79.04, 70.35 APE8-rot-na 28.98 APE67-dihe-in -76.22, -0.44 -56.63, -35.75 APE12-dist-na 22.704 APE11-dist-na 17.972 APE10-dist-na 17.34 APE9-dist-in 7.149 None None None XRAY 2.0 0.215 0.232 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 2wgj TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
2WKMA 1059 1345 1390.0 PFY:2345 Type1 Inactive DFGin 5.71 14.639 BLBplus -142.49, -164.26 57.54, 44.85 -136.55, 165.51 66.62, 94.71 61.32, -132.62 out-out out 14.596 Saltbr-out 12.863 HRD-in -83.33, -52.67 82.5, -15.17 out-out-in SNCooi out-in ActLoopNT-out 10.979 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.21, 106.53 APE9-dihe-in -122.06, 155.91 APE8-dihe-in -79.28, 64.7 APE8-rot-na 31.75 APE67-dihe-in -79.76, -1.27 -59.82, -29.2 APE12-dist-na 22.882 APE11-dist-na 18.107 APE10-dist-na 17.777 APE9-dist-in 7.327 None None None XRAY 2.2 0.218 0.275 A 306 287 0 0 0 0 [[1078, 1339]] 1.0 2wkm TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3ZBXA 1059 1345 1390.0 6XE:2345 Type1 Inactive DFGin 5.12 14.193 BLBplus -133.53, -157.04 42.72, 56.92 -148.81, 166.27 77.97, 91.1 53.49, -129.22 out-out out 14.763 Saltbr-out 12.078 HRD-in -79.72, -52.28 81.84, -11.2 out-out-in SNCooi out-in ActLoopNT-out 10.825 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.5, 113.68 APE9-dihe-in -132.32, 152.54 APE8-dihe-in -79.14, 72.88 APE8-rot-na 29.52 APE67-dihe-in -87.19, -2.39 -66.55, -21.23 APE12-dist-na 22.906 APE11-dist-na 18.11 APE10-dist-na 17.397 APE9-dist-in 7.36 None None None XRAY 2.2 0.179 0.237 A 306 283 4 0 0 0 [[1078, 1339]] 1.0 3zbx TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3ZC5A 1052 1345 1390.0 W9Z:2345 Type1 Inactive DFGin 5.372 14.264 BLBplus -131.02, -159.69 45.54, 54.39 -146.48, 156.9 75.4, 87.57 59.1, -130.23 out-out out 14.903 Saltbr-out 12.537 HRD-in -80.37, -53.07 84.31, -5.5 out-out-in SNCooi out-in ActLoopNT-out 10.711 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -59.62, 118.89 APE9-dihe-in -135.45, 149.7 APE8-dihe-in -76.5, 67.7 APE8-rot-na 27.79 APE67-dihe-in -84.21, -3.17 -61.58, -26.66 APE12-dist-na 23.107 APE11-dist-na 18.375 APE10-dist-na 17.446 APE9-dist-in 7.352 None None None XRAY 2.2 0.204 0.256 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 3zc5 TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3ZCLA 1052 1345 1390.0 5TF:1 Type1 Inactive DFGin 5.341 14.033 BLBplus -130.37, -159.34 48.43, 53.41 -147.61, 165.56 74.15, 92.01 59.61, -131.84 out-out out 14.636 Saltbr-out 12.785 HRD-in -76.45, -51.81 82.5, -13.86 out-out-in SNCooi out-in ActLoopNT-out 10.735 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.5, 109.91 APE9-dihe-in -127.18, 152.9 APE8-dihe-in -78.54, 68.73 APE8-rot-na 30.54 APE67-dihe-in -82.79, -0.65 -60.11, -28.04 APE12-dist-na 22.937 APE11-dist-na 18.131 APE10-dist-na 17.771 APE9-dist-in 7.357 None None None XRAY 1.4 0.194 0.211 A 306 291 3 0 0 0 [[1078, 1339]] 1.0 3zcl TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3ZXZA 1052 1345 1390.0 KRW:2345 Type1 Inactive DFGin 5.343 14.082 BLBplus -135.73, -162.15 50.43, 49.79 -141.07, 164.71 71.86, 91.49 60.06, -132.86 out-out out 14.83 Saltbr-out 12.413 HRD-in -72.98, -56.4 84.76, -11.76 out-out-in SNCooi out-in ActLoopNT-out 10.829 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.31, 115.77 APE9-dihe-in -134.5, 149.99 APE8-dihe-in -77.74, 66.2 APE8-rot-na 31.4 APE67-dihe-in -82.4, 0.31 -58.66, -28.33 APE12-dist-na 23.051 APE11-dist-na 18.283 APE10-dist-na 17.596 APE9-dist-in 7.379 None None None XRAY 1.8 0.185 0.221 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 3zxz TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3ZZEA 1059 1345 1390.0 6XP:2345 Type1 Inactive DFGin 5.344 13.872 BLBplus -124.39, -164.42 52.84, 52.22 -144.64, 167.08 70.9, 89.5 57.01, -128.68 out-out out 14.665 Saltbr-out 12.449 HRD-in -75.38, -48.62 80.64, -12.79 out-out-in SNCooi out-in ActLoopNT-out 10.476 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.32, 110.44 APE9-dihe-in -128.02, 154.15 APE8-dihe-in -79.41, 68.67 APE8-rot-na 30.48 APE67-dihe-in -82.56, 0.41 -59.17, -30.92 APE12-dist-na 22.788 APE11-dist-na 17.994 APE10-dist-na 17.776 APE9-dist-in 7.366 None None None XRAY 1.87 0.196 0.226 A 306 287 0 0 0 0 [[1078, 1339]] 1.0 3zze TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4AOIA 1052 1344 1390.0 4K0:2345 Type1 Inactive DFGin 5.261 14.02 BLBplus -129.93, -161.21 48.66, 52.43 -145.16, 163.98 75.34, 90.8 58.17, -131.76 out-out out 14.801 Saltbr-out 12.571 HRD-in -74.56, -53.23 81.11, -12.36 out-out-in SNCooi out-in ActLoopNT-out 10.798 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.22, 118.1 APE9-dihe-in -136.02, 153.34 APE8-dihe-in -77.45, 67.07 APE8-rot-na 29.7 APE67-dihe-in -82.77, -0.39 -59.05, -28.87 APE12-dist-na 22.904 APE11-dist-na 18.176 APE10-dist-na 17.433 APE9-dist-in 7.302 None None None XRAY 1.9 0.173 0.214 A 306 289 4 0 0 0 [[1078, 1339]] 1.0 4aoi TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4AP7A 1052 1345 1390.0 F47:2345 Type1 Inactive DFGin 5.33 13.973 BLBplus -138.21, -157.46 42.59, 55.52 -147.39, 165.76 73.46, 94.54 64.47, -135.14 out-out out 14.61 Saltbr-out 12.353 HRD-in -75.32, -50.89 81.42, -14.36 out-out-in SNCooi out-in ActLoopNT-out 10.84 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -65.24, 106.32 APE9-dihe-in -126.12, 153.32 APE8-dihe-in -76.65, 65.8 APE8-rot-na 31.12 APE67-dihe-in -83.64, 0.36 -57.49, -29.42 APE12-dist-na 22.755 APE11-dist-na 17.934 APE10-dist-na 17.549 APE9-dist-in 7.331 None None None XRAY 1.8 0.191 0.214 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 4ap7 TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
6SDEA 1068 1346 1390.0 V0L:1401 Type1 Inactive DFGin 5.667 14.258 BLBplus -119.68, -150.47 45.1, 45.32 -137.22, 165.05 73.76, 86.18 57.67, -122.8 out-out out 12.938 Saltbr-out 14.043 HRD-in -63.81, -56.75 81.6, -9.64 out-out-in SNCooi out-in ActLoopNT-out 10.868 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -89.68, 108.89 APE9-dihe-in -113.03, 135.7 APE8-dihe-in -89.2, 66.09 APE8-rot-na 29.11 APE67-dihe-in -72.7, -11.89 -48.71, -38.04 APE12-dist-na 21.428 APE11-dist-na 18.208 APE10-dist-na 16.549 APE9-dist-in 7.37 None None None XRAY 2.49 0.206 0.273 A 309 268 11 0 0 0 [[1078, 1339]] 1.0 6sde TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7Y4TA 1063 1345 1390.0 I90:1401 Type1 Inactive DFGin 5.023 14.284 BLBplus -124.58, -158.37 55.95, 54.1 -154.01, 158.71 78.56, 97.12 63.89, -132.14 out-none out 15.195 Saltbr-none 999.0 HRD-in -78.32, -47.01 69.41, -2.23 none-out-in SNCnoi out-in ActLoopNT-out 10.674 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.01, 118.18 APE9-dihe-in -113.5, 113.09 APE8-dihe-in -81.35, 89.51 APE8-rot-na 28.65 APE67-dihe-in -80.22, 3.63 -53.84, -52.52 APE12-dist-na 17.236 APE11-dist-na 17.468 APE10-dist-na 14.752 APE9-dist-in 6.875 None None None XRAY 2.16 0.216 0.251 A 309 281 2 0 0 0 [[1078, 1339]] 1.0 7y4t TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7Y4UA 1061 1344 1390.0 I94:1401 Type1 Inactive DFGin 5.011 14.109 BLBplus -122.9, -159.94 57.56, 55.67 -154.79, 156.13 77.75, 94.81 65.91, -133.04 out-out out 15.171 Saltbr-out 14.231 HRD-out -102.1, 85.21 -61.9, -6.95 out-out-in SNCooi out-in ActLoopNT-out 10.685 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -100.87, 119.34 APE9-dihe-in -113.64, 116.39 APE8-dihe-in -76.69, 90.17 APE8-rot-na 26.73 APE67-dihe-in -84.74, 7.32 -56.75, -46.15 APE12-dist-na 17.249 APE11-dist-na 17.28 APE10-dist-na 14.971 APE9-dist-in 7.0 None None None XRAY 2.26 0.24 0.278 A 309 281 3 0 0 0 [[1078, 1339]] 1.0 7y4u TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8GVJA 1060 1344 1390.0 KGL:1401 Type1 Inactive DFGin 5.11 14.333 BLBplus -124.62, -159.68 55.58, 59.15 -155.79, 162.16 77.73, 91.46 64.79, -131.96 out-out out 14.78 Saltbr-out 13.973 HRD-in -76.06, -51.5 83.84, -11.14 out-out-in SNCooi out-in ActLoopNT-out 10.985 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.13, 112.88 APE9-dihe-in -113.43, 113.57 APE8-dihe-in -79.76, 93.91 APE8-rot-na 27.28 APE67-dihe-in -81.42, 13.42 -58.79, -51.95 APE12-dist-na 18.793 APE11-dist-na 17.469 APE10-dist-na 15.018 APE9-dist-in 7.02 None None None XRAY 2.71 0.221 0.262 A 309 285 0 0 0 0 [[1078, 1339]] 1.0 8gvj TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8K78A 1048 1345 1390.0 IYC:1401 Type1 Inactive DFGin 5.279 14.37 BLBplus -137.76, -160.13 53.31, 44.71 -142.62, 155.7 79.32, 100.58 65.31, -134.82 out-none out 14.651 Saltbr-none 999.0 HRD-in -77.86, -46.68 52.66, 21.65 none-out-in SNCnoi out-in ActLoopNT-out 10.631 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.34, 117.5 APE9-dihe-in -112.83, 117.81 APE8-dihe-in -78.38, 91.22 APE8-rot-na 27.2 APE67-dihe-in -75.41, 8.19 -65.34, -41.41 APE12-dist-na 17.854 APE11-dist-na 16.52 APE10-dist-na 14.534 APE9-dist-in 6.426 None None None XRAY 2.67 0.244 0.29 A 309 298 0 0 0 0 [[1078, 1339]] 1.0 8k78 TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
9IVBA 1040 1344 1390.0 A1L3A:1401 Type1 Inactive DFGin 5.445 13.892 BLBplus -135.57, -160.44 57.93, 42.99 -140.54, 145.93 73.22, 97.74 72.46, -130.62 out-out out 14.035 Saltbr-out 14.671 HRD-in -68.9, -37.7 81.17, -14.77 out-out-in SNCooi out-in ActLoopNT-out 10.51 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -104.97, 125.97 APE9-dihe-in -120.0, 114.55 APE8-dihe-in -86.52, 80.12 APE8-rot-na 4.22 APE67-dihe-in -65.25, -14.21 -56.14, -42.02 APE12-dist-na 17.521 APE11-dist-na 16.802 APE10-dist-na 14.316 APE9-dist-in 7.123 None None None XRAY 2.35 0.283 0.273 A 309 302 3 0 0 0 [[1078, 1339]] 1.0 9ivb TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
9IVBB 1045 1344 1390.0 A1L3A:1401 Type1 Inactive DFGin 5.18 14.3 BLBplus -124.93, -159.59 53.11, 55.95 -153.33, 151.13 76.29, 94.39 69.12, -130.38 out-out out 14.992 Saltbr-out 13.201 HRD-in -71.02, -54.88 83.43, -14.37 out-out-in SNCooi out-in ActLoopNT-out 10.476 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.51, 120.57 APE9-dihe-in -121.21, 114.93 APE8-dihe-in -85.2, 88.99 APE8-rot-na 28.75 APE67-dihe-in -90.92, 1.7 -64.46, -35.79 APE12-dist-na 17.431 APE11-dist-na 17.105 APE10-dist-na 14.191 APE9-dist-in 7.193 None None None XRAY 2.35 0.283 0.273 B 309 294 6 0 0 0 [[1078, 1339]] 1.0 9ivb TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3I5NA 1052 1346 1390.0 B2D:1 Type1 Inactive DFGin 6.038 14.541 BLBplus -127.28, -154.19 49.83, 50.79 -143.8, 160.7 74.39, 92.8 63.42, -123.71 out-out out 13.617 Saltbr-out 11.311 HRD-in -72.82, -46.99 80.85, -20.31 out-out-none SNCoon out-none ActLoopNT-out 10.72 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 98.91 APE9-dihe-in -107.74, 144.54 APE8-dihe-in -82.26, 63.33 APE8-rot-na 31.79 APE67-dihe-in -74.62, -6.09 -48.49, -39.28 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 17.049 APE9-dist-in 7.337 None None None XRAY 2.0 0.227 0.267 A 309 280 15 0 0 5 [[1078, 1339]] 1.0 3i5n TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4DEGA 1052 1346 1390.0 0JJ:1401 Type1 Inactive DFGin 6.033 14.383 BLBplus -127.22, -154.54 52.1, 48.24 -142.59, 163.7 71.45, 91.63 63.02, -129.14 out-out out 13.271 Saltbr-out 11.67 HRD-in -71.67, -46.99 80.66, -21.62 out-out-in SNCooi out-in ActLoopNT-out 10.688 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.24, 109.16 APE9-dihe-in -113.2, 139.77 APE8-dihe-in -81.91, 65.94 APE8-rot-na 30.64 APE67-dihe-in -74.41, -7.99 -53.82, -35.69 APE12-dist-na 21.598 APE11-dist-na 18.179 APE10-dist-na 17.091 APE9-dist-in 7.395 None None None XRAY 2.0 0.209 0.254 A 309 286 9 0 0 0 [[1078, 1339]] 1.0 4deg TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4DEHA 1053 1346 1390.0 0JK:1401 Type1 Inactive DFGin 6.057 14.528 BLBplus -118.77, -152.18 51.36, 47.51 -147.03, 167.71 74.3, 93.14 59.45, -131.99 out-out out 13.613 Saltbr-out 13.801 HRD-in -73.1, -45.26 76.33, -19.08 out-out-in SNCooi out-in ActLoopNT-out 10.5 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.33, 113.79 APE9-dihe-in -120.5, 140.09 APE8-dihe-in -82.36, 62.75 APE8-rot-na 30.88 APE67-dihe-in -73.8, -10.21 -48.39, -36.82 APE12-dist-na 21.491 APE11-dist-na 18.11 APE10-dist-na 17.084 APE9-dist-in 7.381 None None None XRAY 2.0 0.208 0.259 A 309 286 8 0 0 0 [[1078, 1339]] 1.0 4deh TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4DEIA 1053 1346 1390.0 0JL:1401 Type1 Inactive DFGin 6.121 14.242 BLBplus -122.34, -157.38 50.75, 53.64 -144.41, 169.13 66.13, 83.8 54.4, -127.42 out-out out 13.32 Saltbr-out 13.84 HRD-in -72.66, -45.49 76.43, -21.33 out-out-in SNCooi out-in ActLoopNT-out 10.602 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.14, 102.63 APE9-dihe-in -108.52, 140.65 APE8-dihe-in -82.81, 70.26 APE8-rot-na 30.72 APE67-dihe-in -78.51, -10.8 -58.49, -27.8 APE12-dist-na 21.569 APE11-dist-na 18.042 APE10-dist-na 17.097 APE9-dist-in 7.4 None None None XRAY 2.05 0.224 0.289 A 309 287 7 0 0 0 [[1078, 1339]] 1.0 4dei TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4XMOA 1051 1345 1390.0 46G:1401 Type1 Inactive DFGin 6.061 14.582 BLBplus -129.58, -158.16 50.96, 49.75 -142.1, 164.65 70.02, 93.12 57.3, -130.85 out-out out 13.556 Saltbr-out 13.251 HRD-in -71.94, -50.02 79.17, -15.93 out-out-in SNCooi out-in ActLoopNT-out 10.698 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -89.88, 114.39 APE9-dihe-in -119.44, 138.84 APE8-dihe-in -81.7, 66.87 APE8-rot-na 33.32 APE67-dihe-in -76.96, -5.37 -54.98, -35.22 APE12-dist-na 21.626 APE11-dist-na 18.238 APE10-dist-na 17.102 APE9-dist-in 7.397 None None None XRAY 1.75 0.189 0.238 A 309 289 6 0 0 0 [[1078, 1339]] 1.0 4xmo TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4XYFA 1052 1346 1390.0 44X:1401 Type1 Inactive DFGin 5.955 14.467 BLBplus -129.22, -158.24 51.22, 48.43 -138.73, 167.76 72.05, 90.4 55.51, -128.08 out-out out 13.426 Saltbr-out 12.027 HRD-in -70.98, -46.03 78.03, -20.86 out-out-in SNCooi out-in ActLoopNT-out 10.726 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.7, 109.11 APE9-dihe-in -116.15, 139.41 APE8-dihe-in -78.81, 66.81 APE8-rot-na 36.31 APE67-dihe-in -74.32, -11.26 -55.76, -34.2 APE12-dist-na 21.592 APE11-dist-na 18.328 APE10-dist-na 17.099 APE9-dist-in 7.342 None None None XRAY 1.85 0.188 0.236 A 309 290 5 0 0 0 [[1078, 1339]] 1.0 4xyf TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5EYCA 1053 1345 1390.0 5SZ:1401 Type1 Inactive DFGin 6.049 14.392 BLBplus -124.88, -162.56 54.84, 49.52 -141.18, 168.05 68.53, 92.9 54.54, -130.14 out-out out 13.457 Saltbr-out 13.828 HRD-in -71.93, -50.47 80.12, -18.14 out-out-in SNCooi out-in ActLoopNT-out 10.643 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.28, 111.88 APE9-dihe-in -115.86, 143.23 APE8-dihe-in -81.81, 66.86 APE8-rot-na 33.4 APE67-dihe-in -76.11, -9.46 -54.59, -33.33 APE12-dist-na 21.655 APE11-dist-na 18.189 APE10-dist-na 17.234 APE9-dist-in 7.424 None None None XRAY 1.8 0.195 0.247 A 309 288 5 0 0 0 [[1078, 1339]] 1.0 5eyc TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5EYDA 1052 1348 1390.0 5T1:1401 Type1 Inactive DFGin 6.135 14.363 BLBplus -123.82, -156.55 49.71, 49.92 -139.65, 165.23 70.93, 90.23 56.87, -129.07 out-out out 13.351 Saltbr-out 14.939 HRD-in -69.59, -48.96 78.63, -19.82 out-out-in SNCooi out-in ActLoopNT-out 10.745 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.5, 109.78 APE9-dihe-in -116.31, 141.23 APE8-dihe-in -79.79, 63.19 APE8-rot-na 35.14 APE67-dihe-in -74.55, -9.26 -51.73, -35.89 APE12-dist-na 21.524 APE11-dist-na 18.141 APE10-dist-na 17.07 APE9-dist-in 7.348 None None None XRAY 1.85 0.196 0.249 A 309 289 8 0 0 0 [[1078, 1339]] 1.0 5eyd TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
2RFSA 1067 1346 1390.0 AM8:1 Type1 Inactive DFGin 6.069 13.791 BLBplus -134.84, -164.3 47.97, 50.26 -129.99, 165.29 61.69, 86.55 61.54, -131.37 out-out out 13.021 Saltbr-out 13.367 HRD-in -67.35, -49.82 82.23, -27.14 out-out-in SNCooi out-in ActLoopNT-out 10.393 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -100.22, 107.83 APE9-dihe-in -121.5, 142.78 APE8-dihe-in -78.23, 65.91 APE8-rot-na 30.23 APE67-dihe-in -71.52, -6.3 -48.02, -39.17 APE12-dist-na 20.981 APE11-dist-na 17.387 APE10-dist-na 17.019 APE9-dist-in 7.386 None None None XRAY 2.2 0.226 0.262 A 310 264 16 0 0 2 [[1078, 1339]] 1.0 2rfs TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3CCNA 1055 1346 1390.0 LKG:1 Type1 Inactive DFGin 6.094 14.425 BLBplus -129.45, -153.22 49.92, 50.15 -147.15, 164.18 75.84, 92.59 61.51, -123.83 out-out out 13.227 Saltbr-out 12.591 HRD-in -71.91, -46.5 80.65, -21.52 out-out-in SNCooi out-in ActLoopNT-out 10.633 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.58, 113.44 APE9-dihe-in -120.03, 138.85 APE8-dihe-in -80.52, 67.02 APE8-rot-na 31.14 APE67-dihe-in -74.86, -7.0 -54.1, -35.12 APE12-dist-na 21.706 APE11-dist-na 18.393 APE10-dist-na 17.081 APE9-dist-in 7.312 None None None XRAY 1.9 0.238 0.275 A 310 275 17 0 0 1 [[1078, 1339]] 1.0 3ccn TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3CD8A 1054 1346 1390.0 L5G:1 Type1 Inactive DFGin 5.857 14.446 BLBplus -125.89, -155.49 52.59, 49.22 -144.94, 159.78 75.4, 92.72 64.26, -128.55 out-out out 13.432 Saltbr-out 11.593 HRD-in -72.36, -43.48 78.1, -21.55 out-out-in SNCooi out-in ActLoopNT-out 10.652 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -99.19, 103.8 APE9-dihe-in -110.98, 147.89 APE8-dihe-in -84.36, 67.57 APE8-rot-na 31.76 APE67-dihe-in -76.93, -6.96 -54.37, -34.0 APE12-dist-na 21.24 APE11-dist-na 18.193 APE10-dist-na 17.208 APE9-dist-in 7.328 None None None XRAY 2.0 0.236 0.287 A 310 278 15 0 0 1 [[1078, 1339]] 1.0 3cd8 TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4GG5A 1064 1344 1390.0 0J3:1401 Type1 Inactive DFGin 5.304 14.408 BLBplus -122.37, -151.55 47.45, 47.99 -143.92, 162.16 78.19, 94.77 62.52, -137.98 out-none out 16.212 Saltbr-none 999.0 HRD-in -76.51, -53.12 85.46, -11.68 none-out-in SNCnoi out-in ActLoopNT-out 10.988 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -99.59, 119.56 APE9-dihe-in -118.12, 113.35 APE8-dihe-in -87.92, 83.02 APE8-rot-na 29.52 APE67-dihe-in -78.46, -1.6 -57.29, -40.61 APE12-dist-na 18.282 APE11-dist-na 17.352 APE10-dist-na 14.902 APE9-dist-in 6.873 None None None XRAY 2.423 0.216 0.268 A 319 274 7 0 0 0 [[1078, 1339]] 1.0 4gg5 TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4GG7A 1064 1344 1390.0 0J8:1401 Type1 Inactive DFGin 5.931 14.439 BLBplus -116.6, -141.82 44.91, 50.77 -152.19, 157.95 88.15, 108.92 60.67, -133.34 out-out out 12.027 Saltbr-out 11.294 HRD-in -73.9, -51.35 85.25, -19.01 out-out-in SNCooi out-in ActLoopNT-out 10.967 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.93, 129.1 APE9-dihe-in -123.7, 103.59 APE8-dihe-in -79.6, 83.79 APE8-rot-na 27.48 APE67-dihe-in -83.37, -1.72 -58.24, -36.49 APE12-dist-na 17.613 APE11-dist-na 16.887 APE10-dist-na 14.707 APE9-dist-in 6.687 None None None XRAY 2.27 0.21 0.262 A 319 278 3 0 0 0 [[1078, 1339]] 1.0 4gg7 TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5EOBA 1055 1345 1390.0 5QQ:1401 Type1 Inactive DFGin 6.037 14.739 BLBplus -127.28, -156.67 54.26, 46.24 -141.57, 167.58 71.68, 96.08 59.68, -131.59 out-out out 13.147 Saltbr-out 10.681 HRD-in -72.39, -47.54 73.47, -8.21 out-out-in SNCooi out-in ActLoopNT-out 11.052 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.39, 113.86 APE9-dihe-in -113.77, 125.77 APE8-dihe-in -82.16, 70.22 APE8-rot-na 29.09 APE67-dihe-in -79.07, -3.29 -48.43, -42.18 APE12-dist-na 18.831 APE11-dist-na 18.315 APE10-dist-na 15.59 APE9-dist-in 7.105 None None None XRAY 1.75 0.174 0.197 A 319 288 3 0 0 3 [[1078, 1339]] 1.0 5eob TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5YA5A 1057 1345 1390.0 6TD:1401 Type1 Inactive DFGin 6.047 14.095 BLBplus -131.7, -152.67 53.68, 50.33 -145.36, 163.95 68.46, 89.67 59.78, -131.1 out-none out 16.799 Saltbr-none 999.0 HRD-in -73.73, -48.03 76.19, -12.62 none-out-in SNCnoi out-in ActLoopNT-out 10.896 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.63, 112.14 APE9-dihe-in -120.64, 147.93 APE8-dihe-in -80.59, 71.84 APE8-rot-na 30.4 APE67-dihe-in -73.5, -10.58 -60.93, -29.23 APE12-dist-na 21.585 APE11-dist-na 18.902 APE10-dist-na 17.958 APE9-dist-in 7.29 None None None XRAY 1.89 0.212 0.235 A 319 273 16 0 0 0 [[1078, 1339]] 1.0 5ya5 TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5UABA 1029 1360 1390.0 84M:61401 Type1 Inactive DFGin 6.033 14.28 BLBplus -126.91, -157.0 56.09, 49.1 -144.75, 156.68 72.2, 89.62 65.5, -132.32 out-out out 12.591 Saltbr-out 11.84 HRD-in -69.3, -50.7 81.14, -11.15 out-out-in SNCooi out-in ActLoopNT-out 10.968 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.99, 109.58 APE9-dihe-in -123.38, 147.05 APE8-dihe-in -81.48, 72.06 APE8-rot-na 35.51 APE67-dihe-in -66.4, -17.83 -59.45, -34.1 APE12-dist-na 22.004 APE11-dist-na 18.578 APE10-dist-na 17.571 APE9-dist-in 7.208 None None None XRAY 1.9 0.197 0.229 A 343 288 20 0 0 0 [[1078, 1339]] 1.0 5uab TYR_MET_HUMAN TYR 9.9e-92 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5UADA 1029 1360 1390.0 84P:61401 Type1 Inactive DFGin 6.177 14.121 BLBplus -131.41, -161.35 58.04, 50.15 -144.41, 164.69 67.9, 85.89 61.62, -131.14 out-out out 12.498 Saltbr-out 10.204 HRD-in -69.0, -48.97 78.41, -8.03 out-out-in SNCooi out-in ActLoopNT-out 10.753 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -90.7, 117.76 APE9-dihe-in -129.09, 145.31 APE8-dihe-in -79.01, 73.18 APE8-rot-na 34.82 APE67-dihe-in -68.75, -14.7 -59.66, -32.74 APE12-dist-na 21.462 APE11-dist-na 18.144 APE10-dist-na 17.387 APE9-dist-in 7.154 None None None XRAY 2.25 0.199 0.252 A 343 291 17 0 0 0 [[1078, 1339]] 1.0 5uad TYR_MET_HUMAN TYR 9.9e-92 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
6UBWA 1029 1360 1390.0 84S:61401 Type1 Inactive DFGin 6.156 14.263 BLBplus -131.45, -155.48 54.45, 46.78 -140.26, 163.47 65.89, 85.19 61.55, -131.58 out-out out 12.453 Saltbr-out 11.904 HRD-in -70.83, -47.93 78.68, -11.6 out-out-in SNCooi out-in ActLoopNT-out 11.011 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.43, 111.85 APE9-dihe-in -126.25, 145.85 APE8-dihe-in -81.12, 73.68 APE8-rot-na 35.07 APE67-dihe-in -69.72, -14.3 -61.38, -31.38 APE12-dist-na 21.877 APE11-dist-na 18.515 APE10-dist-na 17.452 APE9-dist-in 7.269 None None None XRAY 2.0 0.189 0.225 A 343 296 12 0 0 0 [[1078, 1339]] 1.0 6ubw TYR_MET_HUMAN TYR 9.9e-92 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3DKGA 1050 1356 1390.0 SX8:1 Type1 Inactive DFGin 6.274 14.559 BLBplus -129.33, -157.14 51.1, 49.15 -145.69, 164.85 74.13, 94.49 54.79, -132.37 out-none out 13.057 Saltbr-none 999.0 HRD-in -67.95, -47.6 75.72, -15.58 none-out-none SNCnon out-none ActLoopNT-out 11.272 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 132.25 APE8-dihe-in -83.72, 63.85 APE8-rot-na 32.57 APE67-dihe-in -77.41, -6.89 -59.3, -29.42 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.562 Y1194F,Y1230L,Y1234F,Y1235D None None XRAY 1.91 0.195 0.238 A 317 281 26 0 0 17 [[1078, 1339]] 1.0 3dkg TYR_MET_HUMAN TYR 2.9e-89 305.2 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
1R0PA 1050 1360 1390.0 KSA:0 Type1 Inactive DFGin 6.476 14.34 BLBplus -128.87, -159.66 55.78, 40.33 -140.55, 160.82 73.45, 94.62 57.22, -140.62 out-out out 12.845 Saltbr-out 8.509 HRD-in -72.32, -48.0 70.71, -31.47 out-out-out SNCooo out-out ActLoopNT-out 11.433 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -136.19, 45.76 APE9-dihe-in -67.34, 140.95 APE8-dihe-in -80.24, 67.34 APE8-rot-na 34.02 APE67-dihe-in -69.09, -8.34 -56.1, -27.84 APE12-dist-na 19.241 APE11-dist-na 22.747 APE10-dist-na 20.477 APE9-dist-out 9.135 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 1.8 0.171 0.197 A 312 301 10 0 0 0 [[1078, 1339]] 1.0 1r0p TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5HNIX 1063 1356 1390.0 63B:1401 Type1 Inactive DFGin 6.582 14.461 BLBplus -128.77, -162.75 58.27, 52.75 -152.11, 164.27 72.11, 107.85 73.64, -141.36 out-out out 12.388 Saltbr-out 10.807 HRD-in -73.69, -52.32 85.1, -22.83 out-out-none SNCoon out-none ActLoopNT-out 11.095 ActLoopCT-none TYR APEdihe_nnnan APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-na 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.71 0.227 0.245 X 312 245 47 0 0 18 [[1078, 1339]] 1.0 5hni TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5HNIY 1063 1356 1390.0 63B:1401 Type1 Inactive DFGin 6.744 14.676 BLBplus -128.6, -162.9 56.36, 57.68 -160.11, 163.59 72.74, 105.71 74.96, -141.42 out-out out 15.004 Saltbr-out 12.553 HRD-in -70.57, -55.83 88.3, -19.62 out-out-none SNCoon out-none ActLoopNT-out 10.921 ActLoopCT-none TYR APEdihe_nnnan APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-na 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.71 0.227 0.245 Y 312 245 47 0 0 18 [[1078, 1339]] 1.0 5hni TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5HO6A 1063 1356 1390.0 63K:1401 Type1 Inactive DFGin 6.392 15.144 BLBplus -140.59, -157.22 42.62, 56.18 -144.55, 164.36 76.38, 97.31 74.25, -133.43 out-out out 13.138 Saltbr-out 11.309 HRD-in -69.03, -58.48 93.08, -20.11 out-out-none SNCoon out-none ActLoopNT-out 11.35 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.63 APE8-dihe-in -80.42, 70.67 APE8-rot-na 33.19 APE67-dihe-in -74.88, -4.04 -52.25, -37.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.252 Y1194F,Y1234F,Y1235D None None XRAY 1.97 999.0 999.0 A 312 240 52 0 0 17 [[1078, 1339]] 1.0 5ho6 TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3QTIA 1052 1360 1390.0 3QT:1 Type1 Inactive DFGin 5.986 14.247 BLBplus -128.5, -152.13 51.75, 55.68 -149.19, 167.26 67.71, 86.54 61.1, -130.78 out-out out 12.791 Saltbr-out 11.363 HRD-in -64.94, -54.68 75.74, -14.73 out-out-out SNCooo out-out ActLoopNT-out 11.085 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -50.26 APE8-dihe-in -81.01, 60.83 APE8-rot-na 28.97 APE67-dihe-in -68.29, -9.03 -49.07, -40.5 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.036 Y1194F,Y1234F,Y1235D None None XRAY 2.0 0.184 0.213 A 314 292 17 0 0 10 [[1078, 1339]] 1.0 3qti TYR_MET_HUMAN TYR 8.4e-90 306.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3QTIB 1058 1360 1390.0 3QT:1 Type1 Inactive DFGin 6.046 14.105 BLBplus -128.94, -152.28 51.92, 56.0 -149.61, 167.07 67.92, 86.59 61.23, -130.04 out-out out 12.391 Saltbr-out 11.833 HRD-in -63.79, -55.32 80.3, -19.96 out-out-out SNCooo out-out ActLoopNT-out 11.086 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -49.95 APE8-dihe-in -81.99, 60.89 APE8-rot-na 28.35 APE67-dihe-in -67.92, -9.06 -48.59, -41.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.071 Y1194F,Y1234F,Y1235D None None XRAY 2.0 0.184 0.213 B 314 280 23 0 0 10 [[1078, 1339]] 1.0 3qti TYR_MET_HUMAN TYR 8.4e-90 306.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3DKFA 1050 1360 1390.0 SX8:60001 Type1 Inactive DFGin 6.26 14.463 BLBplus -127.05, -153.9 49.97, 55.44 -149.93, 164.21 68.29, 85.91 54.3, -128.07 out-none out 13.145 Saltbr-none 999.0 HRD-in -72.55, -46.99 75.69, -17.26 none-out-none SNCnon out-none ActLoopNT-out 10.989 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 80.53 APE9-dihe-in -59.08, 148.93 APE8-dihe-in -81.61, 66.86 APE8-rot-na 29.34 APE67-dihe-in -76.88, -10.9 -58.27, -31.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 19.815 APE9-dist-in 7.622 Y1194F,Y1234F,Y1235D None None XRAY 1.8 0.191 0.233 A 317 293 18 0 0 13 [[1078, 1339]] 1.0 3dkf TYR_MET_HUMAN TYR 8.6e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3A4PA 1063 1360 1390.0 DFQ:1362 Type1 Inactive DFGin 6.091 14.332 BLBplus -133.73, -165.54 69.08, 42.15 -140.6, 163.85 58.15, 78.63 70.77, -133.85 out-out out 12.692 Saltbr-out 11.091 HRD-in -67.67, -48.03 79.13, -18.18 out-out-out SNCooo out-out ActLoopNT-out 10.928 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -62.82, -16.13 APE9-dihe-in -103.62, 128.61 APE8-dihe-in -81.13, 79.24 APE8-rot-na 39.51 APE67-dihe-in -70.65, -14.82 -64.45, -30.75 APE12-dist-na 999.0 APE11-dist-na 21.71 APE10-dist-na 17.268 APE9-dist-in 7.686 Y1194F,Y1234F,Y1235D None None XRAY 2.54 0.186 0.24 A 319 285 13 0 0 10 [[1078, 1339]] 1.0 3a4p TYR_MET_HUMAN TYR 8.8e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5HOAA 1065 1356 1390.0 63K:1401 Type1 Inactive DFGin 6.68 14.954 BLBplus -129.02, -150.36 47.05, 45.12 -132.57, 158.73 62.16, 148.21 76.83, -120.13 out-out out 13.199 Saltbr-out 12.094 HRD-in -69.17, -54.51 81.48, -21.01 out-out-none SNCoon out-none ActLoopNT-out 10.789 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 126.64 APE8-dihe-in -83.0, 61.69 APE8-rot-na 26.13 APE67-dihe-in -70.08, -8.02 -54.44, -40.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.217 None None None XRAY 2.14 999.0 999.0 A 312 225 62 0 0 17 [[1078, 1339]] 1.0 5hoa TYR_MET_HUMAN TYR 4.6e-89 304.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5HORA 1064 1356 1390.0 63K:1401 Type1 Inactive DFGin 5.805 14.002 BLBplus -124.94, -148.7 45.83, 47.65 -141.57, 163.86 75.07, 87.77 65.83, -137.92 out-out out 11.674 Saltbr-out 13.939 HRD-in -69.94, -55.46 81.49, -11.98 out-out-out SNCooo out-out ActLoopNT-out 11.137 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 72.57 APE8-dihe-in -91.32, 77.45 APE8-rot-na 31.4 APE67-dihe-in -70.12, -10.2 -48.97, -48.33 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.163 Y1194F,Y1234F,Y1235D,M1250T None None XRAY 2.2 999.0 999.0 A 312 247 44 0 0 15 [[1078, 1339]] 1.0 5hor TYR_MET_HUMAN TYR 2.5e-89 305.2 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3U6HA 1051 1351 1390.0 03X:1 Type1.5_Front Inactive DFGin 5.5 14.419 BLBplus -145.15, 179.51 61.38, 23.56 -82.38, 149.62 53.62, 89.86 90.75, 999.0 out-out out 12.113 Saltbr-out 7.679 HRD-in -72.28, -53.74 82.85, -16.84 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 50.02 APE8-rot-na 30.69 APE67-dihe-in -72.37, 0.17 -64.56, -34.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.0 0.221 0.274 A 309 280 21 0 0 21 [[1078, 1339]] 1.0 3u6h TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3U6IA 1051 1351 1390.0 044:1 Type1.5_Front Inactive DFGin 5.277 14.587 BLBplus -134.83, 174.49 60.14, 23.77 -73.51, 140.85 47.46, 91.22 78.44, 999.0 out-out out 12.048 Saltbr-out 8.482 HRD-in -67.0, -53.9 81.23, -23.55 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 129.68 APE8-dihe-in -90.4, 68.47 APE8-rot-na 28.01 APE67-dihe-in -76.04, -5.5 -62.36, -28.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.691 None None None XRAY 2.1 0.208 0.257 A 309 281 20 0 0 20 [[1078, 1339]] 1.0 3u6i TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5HLWA 1057 1355 1390.0 62E:1402 Type1 Inactive DFGin 4.513 15.239 BLBtrans -116.03, -153.14 53.76, 45.98 -117.52, 136.96 172.48, 77.03 55.42, -120.5 out-out out 12.132 Saltbr-out 12.527 HRD-in -66.33, -51.4 79.89, -18.18 out-out-in SNCooi out-in ActLoopNT-out 10.958 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.84, 121.53 APE9-dihe-in -119.58, 91.77 APE8-dihe-in -84.22, 69.13 APE8-rot-na 24.1 APE67-dihe-in -74.27, 0.43 -39.16, -50.96 APE12-dist-na 999.0 APE11-dist-na 16.106 APE10-dist-na 13.673 APE9-dist-in 6.72 Y1230H None None XRAY 1.97 999.0 999.0 A 299 284 14 0 0 5 [[1078, 1339]] 1.0 5hlw TYR_MET_HUMAN TYR 1.4e-91 312.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3EFKA 1054 1351 1390.0 MT4:1 Type1.5_Front Inactive DFGin 5.064 14.093 None -134.75, -178.01 61.2, 27.83 -81.51, 999.0 42.72, 82.19 999.0, 999.0 out-out out 12.813 Saltbr-out 7.941 HRD-in -70.71, -51.36 83.62, -19.92 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 26.89 APE8-rot-na 29.1 APE67-dihe-in -75.12, -5.25 -59.44, -32.91 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.2 0.257 0.292 A 310 276 22 0 0 22 [[1078, 1339]] 1.0 3efk TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3EFKB 1054 1351 1390.0 MT4:2 Type1.5_Front Inactive DFGin 5.171 14.171 None -136.11, -178.89 60.83, 31.64 -88.75, 999.0 42.99, 77.64 999.0, 999.0 out-out out 12.549 Saltbr-out 7.623 HRD-in -66.0, -59.6 86.12, -12.02 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 28.71 APE8-rot-na 33.98 APE67-dihe-in -75.58, -3.26 -55.05, -32.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.2 0.257 0.292 B 310 272 26 0 0 22 [[1078, 1339]] 1.0 3efk TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3RHKB 1046 1344 1390.0 M97:1 Type1 Inactive DFGout 16.956 9.456 BBAminus -103.9, 147.08 -123.26, 84.4 -80.96, -74.13 286.43, 109.84 68.17, -76.36 out-none out 18.292 Saltbr-none 999.0 HRD-in -76.8, -46.7 79.69, -10.43 none-out-in SNCnoi out-in ActLoopNT-out 15.535 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.43, 129.46 APE9-dihe-in -122.69, 110.91 APE8-dihe-in -78.44, 71.02 APE8-rot-na 31.3 APE67-dihe-in -74.35, -3.39 -48.6, -48.25 APE12-dist-na 12.656 APE11-dist-na 12.57 APE10-dist-na 10.001 APE9-dist-in 6.793 None None None XRAY 1.94 0.203 0.254 B 318 299 0 0 0 0 [[1078, 1339]] 1.0 3rhk TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8ANSA 1052 1346 1390.0 MDI:1402 Type1.5_Front Inactive DFGout 21.988 12.134 BBAminus -113.69, 156.55 -126.28, 136.74 -116.06, 28.6 291.38, 93.7 114.66, -11.19 out-none out 16.715 Saltbr-none 999.0 HRD-in -66.61, -50.14 72.94, -14.68 none-in-none SNCnin in-none ActLoopNT-in 2.814 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 145.39 APE8-dihe-in -71.16, 118.3 APE8-rot-na 25.27 APE67-dihe-in -73.48, 1.82 -58.2, -31.36 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.972 D1228V None None XRAY 2.01 0.232 0.277 A 296 277 18 0 0 15 [[1078, 1339]] 1.0 8ans TYR_MET_HUMAN TYR 1.3e-91 312.5 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8VI1A 1053 1346 1390.0 A1AB1:1401 Type1.5_Front Inactive DFGout 14.819 9.436 BBAminus -108.11, 147.26 -117.32, 132.26 -96.14, -16.7 282.99, 100.28 74.09, 31.57 out-out out 14.533 Saltbr-out 11.844 HRD-in -73.59, -41.12 80.85, -53.9 out-out-out SNCooo out-out ActLoopNT-out 8.453 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -73.38, 142.57 APE9-dihe-in -84.31, 136.88 APE8-dihe-in -79.64, 70.29 APE8-rot-na 34.05 APE67-dihe-in -83.39, -14.09 -70.01, -29.83 APE12-dist-na 999.0 APE11-dist-na 9.426 APE10-dist-na 10.403 APE9-dist-out 8.627 None None None XRAY 3.11 0.253 0.298 A 309 284 10 0 0 7 [[1078, 1339]] 1.0 8vi1 TYR_MET_HUMAN TYR 1.1e-91 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8VI1B 1050 1345 1390.0 A1AB1:1401 Type1.5_Front Inactive DFGout 15.272 8.725 BBAminus -108.54, 151.43 -123.32, 136.74 -110.22, 12.52 275.64, 111.62 71.37, 50.45 out-out out 15.162 Saltbr-out 11.973 HRD-in -74.07, -53.17 75.69, 9.37 out-out-in SNCooi out-in ActLoopNT-out 7.68 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.88, 110.5 APE9-dihe-in -114.0, 153.27 APE8-dihe-in -80.31, 90.69 APE8-rot-na 32.48 APE67-dihe-in -77.51, -25.6 -72.23, -29.3 APE12-dist-na 999.0 APE11-dist-na 9.908 APE10-dist-na 10.171 APE9-dist-in 7.148 None None None XRAY 3.11 0.253 0.298 B 309 287 9 0 0 9 [[1078, 1339]] 1.0 8vi1 TYR_MET_HUMAN TYR 1.1e-91 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8AN8A 1073 1345 1390.0 MDI:1405 Type1.5_Front Inactive DFGout 21.707 13.171 BBAminus -94.14, 151.51 -120.93, 127.96 -109.22, 32.25 303.58, 88.2 110.31, 1.2 out-out out 16.43 Saltbr-out 20.272 HRD-in -54.67, -51.39 71.04, -1.89 out-in-none SNCoin in-none ActLoopNT-in 2.9 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 58.15 APE8-rot-na 3.41 APE67-dihe-in -68.88, -23.67 -46.98, -37.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.394 0.244 0.298 A 296 244 29 0 0 10 [[1078, 1339]] 1.0 8an8 TYR_MET_HUMAN TYR 5.9e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8AN8B 1058 1345 1390.0 MDI:1402 Type1.5_Front Inactive DFGout 21.849 13.195 BBAminus -106.1, 150.5 -120.05, 128.27 -113.48, 46.76 300.29, 99.64 94.11, -3.01 out-out out 16.643 Saltbr-out 17.83 HRD-in -61.73, -46.11 67.66, -9.48 out-in-none SNCoin in-none ActLoopNT-in 2.97 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 100.6 APE8-dihe-in -76.12, 118.46 APE8-rot-na 29.89 APE67-dihe-in -71.35, -4.52 -60.81, -23.43 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.046 None None None XRAY 2.394 0.244 0.298 B 296 263 25 0 0 9 [[1078, 1339]] 1.0 8an8 TYR_MET_HUMAN TYR 5.9e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
6SDCA 1052 1346 1390.0 88Z:1401 Type2 Inactive DFGout 14.755 9.992 BBAminus -145.61, -169.98 -156.56, 116.19 -59.96, -26.46 279.97, 77.13 50.32, -121.48 in-in in 8.796 Saltbr-in 2.861 HRD-in -66.32, -54.96 80.1, -13.51 in-out-in SNCioi out-in ActLoopNT-out 16.386 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -83.94, 108.39 APE9-dihe-in -108.81, 143.16 APE8-dihe-in -83.72, 68.12 APE8-rot-na 31.17 APE67-dihe-in -78.0, -5.37 -48.86, -37.15 APE12-dist-na 999.0 APE11-dist-na 13.258 APE10-dist-na 11.102 APE9-dist-in 7.166 D1228V None None XRAY 1.67 0.203 0.242 A 309 286 9 0 0 5 [[1078, 1339]] 1.0 6sdc TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
6SDDA 1062 1344 1390.0 353:1401 Type2 Inactive DFGout 15.67 9.526 BBAminus -149.49, -170.93 -153.94, 114.14 -65.06, -13.55 275.17, 88.26 76.54, -107.92 out-out out 12.411 Saltbr-out 7.347 HRD-in -67.87, -54.54 79.9, -17.29 out-out-in SNCooi out-in ActLoopNT-out 17.253 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.26, 119.13 APE9-dihe-in -121.4, 98.95 APE8-dihe-in -84.87, 81.64 APE8-rot-na 25.83 APE67-dihe-in -76.62, 2.13 -39.71, -53.85 APE12-dist-na 11.436 APE11-dist-na 11.546 APE10-dist-na 6.815 APE9-dist-in 6.618 D1228V None None XRAY 1.93 0.211 0.23 A 309 271 12 0 0 0 [[1078, 1339]] 1.0 6sdd TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
9C1RA 1048 1348 1390.0 A1ATS:61402 Type2 Inactive DFGout 14.996 12.36 BBAminus -147.48, -173.02 -151.09, 114.21 -68.49, -19.37 279.38, 51.8 69.45, 999.0 in-out in 8.466 Saltbr-out 4.388 HRD-in -73.44, -51.96 79.97, -12.22 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 71.42 APE8-rot-na 34.84 APE67-dihe-in -69.08, -15.96 -61.0, -31.76 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 D1228N None None XRAY 1.59 0.17 0.195 A 307 280 21 0 0 21 [[1078, 1339]] 1.0 9c1r TYR_MET_HUMAN TYR 1e-91 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3LQ8A 1053 1345 1390.0 88Z:1 Type2 Inactive DFGout 14.861 9.989 BBAminus -150.09, -172.74 -147.86, 117.02 -56.28, -26.81 274.5, 87.89 59.54, -126.97 in-in in 8.647 Saltbr-in 2.7 HRD-in -70.16, -54.71 79.85, -12.74 in-out-in SNCioi out-in ActLoopNT-out 16.446 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.38, 117.69 APE9-dihe-in -124.2, 124.76 APE8-dihe-in -78.42, 71.53 APE8-rot-na 27.34 APE67-dihe-in -76.25, -4.88 -56.16, -37.64 APE12-dist-na 999.0 APE11-dist-na 14.007 APE10-dist-na 9.891 APE9-dist-in 7.129 None None None XRAY 2.02 0.194 0.252 A 302 278 15 0 0 8 [[1078, 1339]] 1.0 3lq8 TYR_MET_HUMAN TYR 6.4e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
6SD9A 1062 1345 1390.0 88Z:1402 Type2 Inactive DFGout 14.875 10.089 BBAminus -142.16, -169.29 -149.74, 121.34 -65.96, -2.71 275.09, 79.25 44.01, -118.14 in-in in 8.835 Saltbr-in 3.063 HRD-in -63.65, -57.37 87.84, -32.21 in-out-in SNCioi out-in ActLoopNT-out 15.81 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -103.67, 97.49 APE9-dihe-in -110.0, 137.15 APE8-dihe-in -89.8, 72.46 APE8-rot-na 28.25 APE67-dihe-in -72.7, -14.18 -53.41, -37.28 APE12-dist-na 14.557 APE11-dist-na 14.701 APE10-dist-na 9.852 APE9-dist-in 7.607 None None None XRAY 2.35 0.212 0.27 A 309 265 19 0 0 9 [[1078, 1339]] 1.0 6sd9 TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4EEVA 1045 1346 1390.0 L1X:1401 Type2 Inactive DFGout 14.835 11.811 BBAminus -150.99, -173.15 -148.09, 112.51 -69.31, -18.69 280.19, 68.72 62.91, 999.0 in-out in 9.438 Saltbr-out 4.019 HRD-in -69.54, -52.28 78.43, -16.27 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -34.59 APE9-dihe-in -112.24, 136.57 APE8-dihe-in -76.84, 69.93 APE8-rot-na 35.57 APE67-dihe-in -75.09, -8.21 -54.81, -37.27 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.399 None None None XRAY 1.8 0.19 0.215 A 317 283 19 0 0 19 [[1078, 1339]] 1.0 4eev TYR_MET_HUMAN TYR 7.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
4MXCA 1052 1346 1390.0 DWF:1401 Type2 Inactive DFGout 14.41 10.337 BBAminus -151.35, -174.18 -156.99, 122.43 -67.95, -16.78 287.52, 70.23 58.23, -116.98 in-in in 8.929 Saltbr-in 3.515 HRD-in -73.25, -51.06 80.68, -17.87 in-out-in SNCioi out-in ActLoopNT-out 15.287 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.68, 108.68 APE9-dihe-in -118.71, 133.81 APE8-dihe-in -79.71, 72.93 APE8-rot-na 28.81 APE67-dihe-in -75.71, -5.79 -60.94, -31.89 APE12-dist-na 999.0 APE11-dist-na 13.628 APE10-dist-na 10.273 APE9-dist-in 7.344 None None None XRAY 1.632 0.18 0.207 A 319 290 5 0 0 5 [[1078, 1339]] 1.0 4mxc TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5HTIA 1052 1346 1390.0 66L:1401 Type2 Inactive DFGout 14.763 10.152 BBAminus -150.22, -171.22 -155.42, 114.97 -62.9, -20.19 274.11, 85.9 55.43, -118.13 in-in in 8.699 Saltbr-in 2.823 HRD-in -77.45, -49.55 78.7, -14.93 in-out-in SNCioi out-in ActLoopNT-out 15.499 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.35, 116.23 APE9-dihe-in -109.51, 139.44 APE8-dihe-in -78.22, 74.02 APE8-rot-na 29.94 APE67-dihe-in -80.7, -2.62 -63.3, -30.0 APE12-dist-na 999.0 APE11-dist-na 12.385 APE10-dist-na 10.932 APE9-dist-in 7.21 None None None XRAY 1.66 0.182 0.206 A 319 290 5 0 0 5 [[1078, 1339]] 1.0 5hti TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7V3SA 1053 1346 1390.0 5I9:61401 Type2 Inactive DFGout 14.757 10.258 BBAminus -149.82, -171.75 -156.83, 112.28 -60.3, -21.2 277.0, 84.81 61.69, -129.71 in-in in 8.631 Saltbr-in 2.978 HRD-in -72.86, -54.04 83.09, -13.67 in-out-in SNCioi out-in ActLoopNT-out 15.578 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.7, 113.54 APE9-dihe-in -114.51, 140.19 APE8-dihe-in -79.44, 72.02 APE8-rot-na 33.09 APE67-dihe-in -77.15, -5.33 -64.06, -28.7 APE12-dist-na 999.0 APE11-dist-na 13.959 APE10-dist-na 10.578 APE9-dist-in 7.339 None None None XRAY 1.9 0.166 0.195 A 319 284 10 0 0 10 [[1078, 1339]] 1.0 7v3s TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3VW8A 1024 1352 1390.0 DF6:61401 Type2 Inactive DFGout 14.985 9.691 BBAminus -161.12, -169.12 -159.8, 118.44 -64.07, -25.07 277.76, 84.74 53.88, -122.36 in-in in 8.069 Saltbr-in 2.768 HRD-in -68.84, -53.41 80.47, -15.73 in-out-in SNCioi out-in ActLoopNT-out 16.135 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.55, 104.4 APE9-dihe-in -121.2, 146.4 APE8-dihe-in -81.53, 72.39 APE8-rot-na 32.73 APE67-dihe-in -70.52, -13.63 -60.67, -36.33 APE12-dist-na 999.0 APE11-dist-na 13.724 APE10-dist-na 10.723 APE9-dist-in 7.187 None None None XRAY 2.1 0.215 0.259 A 328 303 11 0 0 6 [[1078, 1339]] 1.0 3vw8 TYR_MET_HUMAN TYR 8.5e-92 313.4 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3CE3A 1054 1360 1390.0 1FN:1401 Type2 Inactive DFGout 15.829 11.096 BBAminus -152.23, -166.63 -149.31, 110.67 -63.52, 88.97 263.94, 98.6 -40.81, 999.0 out-out out 10.457 Saltbr-out 7.572 HRD-in -64.74, -51.71 83.06, -16.24 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 154.52, -34.98 APE9-dihe-in -91.22, 168.57 APE8-dihe-in -87.87, 55.4 APE8-rot-na 29.31 APE67-dihe-in -83.51, -5.01 -45.55, -24.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.489 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 2.4 0.209 0.275 A 314 293 14 0 0 14 [[1078, 1339]] 1.0 3ce3 TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3CTHA 1052 1360 1390.0 319:2001 Type2 Inactive DFGout 15.098 10.005 BBAminus -148.1, -166.94 -151.56, 109.98 -65.26, 53.17 258.77, 111.11 -176.8, 999.0 out-out out 10.323 Saltbr-out 4.075 HRD-in -66.61, -58.23 83.78, -12.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -74.2, -8.67 APE9-dihe-in -55.09, 119.34 APE8-dihe-in -75.87, 63.89 APE8-rot-na 35.54 APE67-dihe-in -72.56, -7.97 -55.16, -26.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.642 Y1194F,Y1234F,Y1235D None None XRAY 2.3 0.212 0.273 A 314 295 14 0 0 14 [[1078, 1339]] 1.0 3cth TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3F82A 1055 1360 1390.0 353:2001 Type2 Inactive DFGout 15.478 9.639 BBAminus -148.75, -169.98 -153.95, 103.18 -56.5, -43.04 270.25, 97.71 47.11, 999.0 out-out out 10.115 Saltbr-out 5.31 HRD-in -72.25, -53.17 82.39, -19.33 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 37.94 APE9-dihe-in -74.59, 146.36 APE8-dihe-in -82.33, 66.47 APE8-rot-na 33.58 APE67-dihe-in -70.27, -11.92 -52.54, -32.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.373 Y1194F,Y1234F,Y1235D None None XRAY 2.5 0.183 0.253 A 314 278 28 0 0 19 [[1078, 1339]] 1.0 3f82 TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3L8VA 1054 1360 1390.0 L8V:1 Type2 Inactive DFGout 15.382 9.641 BBAminus -142.33, -172.03 -148.67, 112.08 -62.2, -49.07 262.9, 96.95 155.4, 999.0 in-out in 9.132 Saltbr-out 4.512 HRD-in -64.23, -54.91 82.78, -23.22 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -164.33, -4.28 APE9-dihe-in -77.45, 145.0 APE8-dihe-in -83.45, 66.14 APE8-rot-na 33.01 APE67-dihe-in -69.99, -14.31 -48.56, -35.56 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.505 Y1194F,Y1234F,Y1235D None None XRAY 2.4 0.185 0.237 A 314 293 14 0 0 14 [[1078, 1339]] 1.0 3l8v TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OUUA 1059 1346 1390.0 W49:1404 Type3 Inactive DFGout 13.515 6.876 BBAminus -147.46, -168.73 -151.04, 108.81 -112.08, 40.61 288.5, 94.51 -110.14, -161.37 out-out out 12.355 Saltbr-out 10.46 HRD-in -63.12, -55.99 76.4, -17.82 out-out-in SNCooi out-in ActLoopNT-out 9.091 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.11, 150.07 APE9-dihe-in -72.2, 149.25 APE8-dihe-in -80.89, 58.5 APE8-rot-na 27.43 APE67-dihe-in -74.53, -1.63 -44.12, -49.33 APE12-dist-na 999.0 APE11-dist-na 6.546 APE10-dist-na 10.792 APE9-dist-in 7.893 D1228V None None XRAY 1.77 0.203 0.225 A 309 284 4 0 0 4 [[1078, 1339]] 1.0 8ouu TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OUUB 1057 1346 1390.0 W49:1405 Type3 Inactive DFGout 13.488 6.97 BBAminus -144.89, -171.19 -149.83, 102.26 -101.8, 30.99 273.18, 101.18 -108.36, -152.3 out-out out 12.311 Saltbr-out 10.383 HRD-in -62.48, -51.05 73.17, -16.23 out-out-out SNCooo out-out ActLoopNT-out 9.188 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -63.11, 139.96 APE9-dihe-in -71.28, 138.06 APE8-dihe-in -78.82, 59.01 APE8-rot-na 36.37 APE67-dihe-in -74.44, -3.9 -45.73, -43.18 APE12-dist-na 10.634 APE11-dist-na 6.56 APE10-dist-na 11.61 APE9-dist-out 8.235 D1228V None None XRAY 1.77 0.203 0.225 B 309 290 0 0 0 0 [[1078, 1339]] 1.0 8ouu TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OUVA 1053 1346 1390.0 W3R:1401 Type3 Inactive DFGout 13.432 6.982 BBAminus -150.55, -166.67 -153.94, 107.37 -108.14, 42.08 281.33, 84.2 -114.79, -152.59 out-out out 12.492 Saltbr-out 10.788 HRD-in -65.45, -52.15 77.68, -39.15 out-out-out SNCooo out-out ActLoopNT-out 9.594 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -77.07, 137.88 APE9-dihe-in -75.04, 140.45 APE8-dihe-in -83.02, 58.2 APE8-rot-na 29.39 APE67-dihe-in -74.39, -2.19 -46.6, -48.03 APE12-dist-na 10.641 APE11-dist-na 6.116 APE10-dist-na 10.331 APE9-dist-out 8.21 D1228V None None XRAY 1.783 0.193 0.22 A 309 294 0 0 0 0 [[1078, 1339]] 1.0 8ouv TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OUVB 1057 1346 1390.0 W3R:1403 Type3 Inactive DFGout 13.51 7.147 BBAminus -147.83, -171.85 -148.7, 102.33 -101.0, 36.34 274.67, 80.19 -118.46, -149.43 out-out out 12.359 Saltbr-out 10.666 HRD-in -65.36, -51.5 76.95, -23.29 out-out-out SNCooo out-out ActLoopNT-out 9.126 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -67.24, 136.99 APE9-dihe-in -67.7, 139.76 APE8-dihe-in -82.33, 58.02 APE8-rot-na 32.55 APE67-dihe-in -77.97, -2.31 -52.96, -31.41 APE12-dist-na 10.989 APE11-dist-na 6.865 APE10-dist-na 11.983 APE9-dist-out 8.293 D1228V None None XRAY 1.783 0.193 0.22 B 309 290 0 0 0 0 [[1078, 1339]] 1.0 8ouv TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OV7A 1051 1346 1390.0 W3W:1401 Type3 Inactive DFGout 16.903 9.364 BBAminus -153.61, -165.39 -151.4, 119.76 -84.83, -13.59 281.18, 90.67 -96.35, -144.67 out-out out 12.327 Saltbr-out 10.74 HRD-in -65.11, -52.02 80.74, -20.69 out-out-out SNCooo out-out ActLoopNT-out 6.49 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -77.6, 93.42 APE9-dihe-in -116.32, 89.67 APE8-dihe-out -52.96, -30.95 APE8-rot-na 334.19 APE67-dihe-in -78.41, -2.44 -56.72, -27.38 APE12-dist-na 16.993 APE11-dist-na 17.033 APE10-dist-na 11.812 APE9-dist-out 10.786 D1228V None None XRAY 1.95 0.274 0.287 A 309 289 7 0 0 0 [[1078, 1339]] 1.0 8ov7 TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OVZA 1061 1346 1390.0 W3N:1411 Type3 Inactive DFGout 13.353 7.006 BBAminus -146.53, -171.32 -145.54, 124.96 -119.17, 42.96 279.31, 88.35 -118.39, -154.9 out-out out 12.132 Saltbr-out 11.597 HRD-in -61.66, -54.56 76.63, -30.67 out-out-out SNCooo out-out ActLoopNT-out 9.29 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -75.2, 144.98 APE9-dihe-in -69.5, 147.31 APE8-dihe-in -82.74, 56.17 APE8-rot-na 31.37 APE67-dihe-in -67.83, -2.09 -44.04, -52.84 APE12-dist-na 10.733 APE11-dist-na 6.553 APE10-dist-na 11.677 APE9-dist-out 8.152 D1228V None None XRAY 2.206 0.227 0.275 A 309 286 0 0 0 0 [[1078, 1339]] 1.0 8ovz TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OVZB 1057 1346 1390.0 W3N:1410 Type3 Inactive DFGout 13.772 6.771 BBAminus -146.01, -169.05 -148.05, 116.27 -112.98, 47.33 264.21, 88.29 -128.7, -142.69 out-out out 12.232 Saltbr-out 11.019 HRD-in -68.15, -51.01 72.21, -18.47 out-out-out SNCooo out-out ActLoopNT-out 9.007 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -70.33, 137.86 APE9-dihe-in -70.76, 127.71 APE8-dihe-in -79.23, 64.44 APE8-rot-na 29.84 APE67-dihe-in -76.38, -8.07 -54.71, -26.75 APE12-dist-na 10.89 APE11-dist-na 6.759 APE10-dist-na 11.936 APE9-dist-out 8.433 D1228V None None XRAY 2.206 0.227 0.275 B 309 290 0 0 0 0 [[1078, 1339]] 1.0 8ovz TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OWGA 1060 1344 1390.0 W40:1401 Type3 Inactive DFGout 15.215 7.185 BBAminus -151.69, 176.81 -129.27, 111.57 -101.99, 63.08 247.0, 19.93 135.49, 100.91 out-none out 12.564 Saltbr-none 999.0 HRD-in -54.29, -59.14 87.34, -18.08 none-out-none SNCnon out-none ActLoopNT-out 6.455 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 39.54 APE8-rot-na 32.71 APE67-dihe-in -69.3, -0.31 -58.16, -36.16 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 D1228V None None XRAY 2.631 0.283 0.329 A 309 244 41 0 0 17 [[1078, 1339]] 1.0 8owg TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OWGB 1060 1343 1390.0 W40:1401 Type3 Inactive DFGout 13.474 7.027 BBAminus -143.52, -173.91 -145.15, 96.11 -104.84, 19.11 287.04, 87.7 -144.89, 36.92 out-none out 12.676 Saltbr-none 999.0 HRD-in -57.0, -54.53 71.26, 2.24 none-out-in SNCnoi out-in ActLoopNT-out 8.803 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.21, 155.54 APE9-dihe-in -138.84, 156.19 APE8-dihe-in -90.42, 73.4 APE8-rot-na 26.27 APE67-dihe-in -74.77, 0.81 -53.95, -37.48 APE12-dist-na 13.969 APE11-dist-na 10.934 APE10-dist-na 9.933 APE9-dist-in 7.283 D1228V None None XRAY 2.631 0.283 0.329 B 309 246 38 0 0 14 [[1078, 1339]] 1.0 8owg TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OWGC 1060 1343 1390.0 W40:1401 Type3 Inactive DFGout 13.494 7.396 BBAminus -137.63, 176.74 -129.85, 94.81 -103.25, 51.6 272.59, 87.18 162.66, 999.0 out-none out 12.719 Saltbr-none 999.0 HRD-in -60.14, -44.34 69.98, -16.33 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.95 APE8-dihe-in -84.26, 62.47 APE8-rot-na 30.42 APE67-dihe-in -68.37, 4.72 -58.51, -48.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.132 D1228V None None XRAY 2.631 0.283 0.329 C 309 235 49 0 0 20 [[1078, 1339]] 1.0 8owg TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
8OW3A 1058 1345 1390.0 W40:1401 Type3 Inactive DFGout 13.282 6.949 BBAminus -144.85, -172.89 -148.19, 116.28 -124.16, 31.55 280.56, 89.39 -106.2, 999.0 out-none out 12.663 Saltbr-none 999.0 HRD-in -58.32, -54.99 72.45, -5.24 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 130.74 APE8-dihe-in -87.02, 65.42 APE8-rot-na 27.11 APE67-dihe-in -76.81, 1.52 -53.65, -34.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.743 None None None XRAY 2.27 0.247 0.295 A 309 258 30 0 0 20 [[1078, 1339]] 1.0 8ow3 TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3RHKA 1049 1346 1390.0 M97:1 Type1 Inactive DFGout 16.804 10.238 None -104.85, 145.39 -125.11, 99.2 -79.8, 96.93 312.95, 103.75 -66.36, -102.37 out-out out 17.662 Saltbr-out 17.877 HRD-in -66.53, -55.84 80.88, -14.04 out-out-in SNCooi out-in ActLoopNT-out 14.853 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.18, 132.08 APE9-dihe-in -131.35, 110.62 APE8-dihe-in -80.24, 69.86 APE8-rot-na 30.58 APE67-dihe-in -67.83, -6.07 -48.09, -47.84 APE12-dist-na 13.045 APE11-dist-na 12.499 APE10-dist-na 10.098 APE9-dist-in 7.007 None None None XRAY 1.94 0.203 0.254 A 318 298 0 0 0 0 [[1078, 1339]] 1.0 3rhk TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3EFJA 1054 1351 1390.0 MT3:1 Type1.5_Front Inactive DFGout 14.778 8.785 None -121.25, 162.39 -104.89, -29.61 54.56, 999.0 265.44, 110.5 999.0, 999.0 out-out out 13.253 Saltbr-out 9.71 HRD-in -61.96, -46.17 77.81, -13.58 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 59.71 APE8-rot-na 30.83 APE67-dihe-in -80.48, 4.82 -65.53, -29.2 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.6 0.247 0.288 A 310 276 22 0 0 22 [[1078, 1339]] 1.0 3efj TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5DG5A 1050 1346 1390.0 5B4:1401 Type2 Inactive DFGout 15.245 8.981 None -148.03, 172.77 -125.96, 63.08 -65.16, -43.8 189.97, 16.62 73.98, -1.88 in-out in 9.264 Saltbr-out 3.8 HRD-in -77.46, -50.65 83.37, -30.01 out-out-in SNCooi out-in ActLoopNT-out 21.352 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.57, 108.34 APE9-dihe-in -125.39, 83.42 APE8-dihe-in -80.42, 85.64 APE8-rot-na 33.34 APE67-dihe-in -79.25, -5.1 -56.96, -39.29 APE12-dist-na 16.235 APE11-dist-na 16.527 APE10-dist-na 11.188 APE9-dist-in 6.946 None None None XRAY 2.6 0.206 0.245 A 318 297 0 0 0 0 [[1078, 1339]] 1.0 5dg5 TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5DG5B 1050 1346 1390.0 5B4:1401 Type2 Inactive DFGout 15.26 8.971 None -148.45, 172.71 -124.98, 61.77 -64.55, -43.29 189.3, 16.8 74.05, -2.15 in-out in 9.308 Saltbr-out 3.828 HRD-in -77.28, -50.39 83.54, -30.49 out-out-in SNCooi out-in ActLoopNT-out 21.316 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.76, 106.09 APE9-dihe-in -126.22, 85.06 APE8-dihe-in -81.11, 86.98 APE8-rot-na 32.68 APE67-dihe-in -78.84, -4.43 -58.19, -40.13 APE12-dist-na 16.146 APE11-dist-na 16.267 APE10-dist-na 10.94 APE9-dist-in 6.94 None None None XRAY 2.6 0.206 0.245 B 318 297 0 0 0 0 [[1078, 1339]] 1.0 5dg5 TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
7V3RA 1053 1346 1390.0 5IE:1401 Type2 Inactive DFGout 16.131 9.536 None -154.01, 179.09 -125.93, 64.92 -46.8, -55.86 193.46, 7.97 68.82, 17.14 in-out in 8.92 Saltbr-out 3.772 HRD-in -77.59, -50.53 81.74, -18.75 out-out-none SNCoon out-none ActLoopNT-out 15.98 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.44 APE8-dihe-in -82.46, 69.73 APE8-rot-na 32.94 APE67-dihe-in -75.0, -5.3 -63.05, -31.28 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.192 None None None XRAY 1.7 0.169 0.19 A 319 285 9 0 0 8 [[1078, 1339]] 1.0 7v3r TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3CTJA 1051 1360 1390.0 320:2001 Type2 Inactive DFGout 15.628 12.374 None -151.35, -169.91 -155.14, 109.57 -58.4, 999.0 273.45, 76.65 999.0, 999.0 in-in in 8.625 Saltbr-in 3.415 HRD-in -67.75, -57.75 90.09, -21.81 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.13 APE8-dihe-in -85.42, 67.16 APE8-rot-na 33.85 APE67-dihe-in -71.85, -7.28 -60.58, -28.25 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.765 Y1194F,Y1234F,Y1235D None None XRAY 2.5 0.209 0.261 A 314 289 21 0 0 21 [[1078, 1339]] 1.0 3ctj TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3C1XA 1050 1360 1390.0 CKK:1500 Type2 Inactive DFGout 15.699 8.64 None -151.42, -165.64 -150.75, 113.01 -101.01, 999.0 199.98, 57.96 999.0, 999.0 in-out in 9.454 Saltbr-out 8.485 HRD-in -59.89, -58.33 82.48, -12.42 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.31 APE8-dihe-in -79.79, 76.14 APE8-rot-na 30.37 APE67-dihe-in -67.75, -12.09 -55.44, -37.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.298 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 2.17 0.208 0.262 A 373 290 21 0 0 21 [[1078, 1339]] 1.0 3c1x TYR_MET_HUMAN TYR 1.5e-89 307.2 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
5T3QA 1050 1350 1390.0 75H:61401 Type1.5_Front Inactive None 999.0 999.0 None -142.6, 175.57 45.45, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 12.187 Saltbr-out 9.495 HRD-in -69.85, -55.7 82.52, -23.62 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 169.98 APE8-dihe-in -92.78, 65.48 APE8-rot-na 37.33 APE67-dihe-in -70.53, -2.22 -62.22, -34.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.582 None None None XRAY 2.0 0.198 0.248 A 309 277 24 0 0 22 [[1078, 1339]] 1.0 5t3q TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
2RFNA 1057 1351 1390.0 AM7:1 Type1.5_Front Inactive None 999.0 999.0 None -145.52, 173.92 -137.55, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 13.313 Saltbr-out 10.101 HRD-in -80.8, -43.71 73.65, -29.19 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 31.17 APE8-rot-na 23.12 APE67-dihe-in -68.97, -9.97 -50.29, -35.3 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.241 0.294 A 310 268 27 0 0 23 [[1078, 1339]] 1.0 2rfn TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
2RFNB 1056 1351 1390.0 AM7:1 Type1.5_Front Inactive None 999.0 999.0 None -149.27, 171.85 -132.94, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 13.46 Saltbr-out 10.805 HRD-in -77.04, -45.81 74.29, -30.03 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 33.53 APE8-rot-na 35.74 APE67-dihe-in -65.01, -12.86 -49.25, -36.6 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.241 0.294 B 310 269 27 0 0 23 [[1078, 1339]] 1.0 2rfn TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
3EFJB 1054 1351 1390.0 MT3:2 Type1.5_Front Inactive None 999.0 999.0 None -130.74, -175.38 -145.16, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-none out 13.373 Saltbr-none 999.0 HRD-in -71.19, -53.04 82.76, -19.12 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -10.37 APE8-rot-na 31.62 APE67-dihe-in -71.17, -12.51 -66.7, -29.99 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.6 0.247 0.288 B 310 275 23 0 0 23 [[1078, 1339]] 1.0 3efj TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

TYR_MET (Hepatocyte growth factor receptor)

Total number of chains: 126
Active chains: 2
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 75 59.5% 3DKCA
DFGout BBAminus 31 24.6% 8OUUB
DFGout None 7 5.6% 3RHKA
None None 4 3.2% 3EFJB
DFGin ABAminus 3 2.4% 3Q6WA
DFGin BLAminus 2 1.6% AF-P08581-K1A
DFGin None 2 1.6% 3EFKA
DFGin BLBminus 1 0.8% 3Q6UA
DFGin BLBtrans 1 0.8% 5HLWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MET_HUMAN AF-P08581-K1A P08581 1068 1347 1390.0 No_ligand No_ligand Active DFGin 6.61 14.387 BLAminus -141.76, -176.05 55.59, 75.76 -89.46, 14.38 301.99, 115.12 -58.79, -29.71 in-in in 8.321 Saltbr-in 2.676 HRD-in -73.97, -41.75 66.87, -17.49 in-in-in SNCiii in-in ActLoopNT-in 3.27 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.23, 99.49 APE9-dihe-in -81.99, 148.85 APE8-dihe-in -79.26, 65.28 APE8-rot-na 37.58 APE67-dihe-in -73.73, -13.28 -44.92, -39.54 APE12-dist-na 12.49 APE11-dist-na 7.881 APE10-dist-na 10.604 APE9-dist-in 6.706 None None None AF2 -1.0 1.0 1.0 A 280 280 0 0 0 0 [[1078, 1339]] 1.0 AF-P08581-K1 Homo sapiens TYR_MET_HUMAN TYR 4.8e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN AF-P08581-K3A P08581 1068 1347 1390.0 No_ligand No_ligand Active DFGin 6.29 14.454 BLAminus -144.17, -175.7 57.67, 71.22 -86.62, 14.75 300.5, 104.92 -59.08, -33.54 in-in in 8.552 Saltbr-in 2.682 HRD-in -80.38, -43.65 66.25, -13.46 in-in-in SNCiii in-in ActLoopNT-in 2.893 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.57, 87.82 APE9-dihe-in -84.23, 145.95 APE8-dihe-in -81.54, 62.86 APE8-rot-na 37.83 APE67-dihe-in -72.05, -14.12 -45.52, -36.53 APE12-dist-na 12.513 APE11-dist-na 8.566 APE10-dist-na 9.904 APE9-dist-in 6.223 None None None AF2 -1.0 1.0 1.0 A 280 280 0 0 0 0 [[1078, 1339]] 1.0 AF-P08581-K3 Homo sapiens TYR_MET_HUMAN TYR 4.8e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4IWDA P08581 1048 1348 1390.0 AME:50001,1JC:61401 Allosteric,Type1 Inactive DFGin 6.543 14.301 ABAminus -108.09, -32.72 -101.39, 130.91 -125.93, 29.16 298.42, 93.31 -62.5, -20.72 in-in in 7.543 Saltbr-in 2.682 HRD-in -68.72, -51.93 72.01, -13.84 in-in-none SNCiin in-none ActLoopNT-in 2.864 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -44.03 APE9-dihe-in -64.62, 131.07 APE8-dihe-in -85.04, 84.89 APE8-rot-na 35.71 APE67-dihe-in -69.34, -7.33 -42.52, -52.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 7.704 APE9-dist-in 6.106 None PTR1234,PTR1235 PTR1234,PTR1235 XRAY 1.99 0.207 0.257 A 306 297 4 0 0 4 [[1078, 1339]] 1.0 4iwd Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3Q6WA P08581 1050 1348 1390.0 Q6W:60001 Type1 Inactive DFGin 6.557 14.212 ABAminus -113.39, -31.38 -103.35, 133.16 -129.6, 28.19 294.61, 91.16 -57.03, -25.46 in-in in 7.727 Saltbr-in 2.744 HRD-in -76.23, -49.43 72.94, -9.8 in-in-none SNCiin in-none ActLoopNT-in 2.828 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 20.1 APE9-dihe-in -70.96, 140.5 APE8-dihe-in -77.07, 74.54 APE8-rot-na 32.13 APE67-dihe-in -73.0, -2.61 -44.68, -48.59 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.073 APE9-dist-in 6.837 None PTR1234,PTR1235 PTR1234,PTR1235 XRAY 1.75 0.205 0.227 A 307 295 4 0 0 4 [[1078, 1339]] 1.0 3q6w Homo sapiens TYR_MET_HUMAN TYR 6.8e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3R7OA P08581 1048 1348 1390.0 M61:60001 Type1 Inactive DFGin 6.538 14.144 ABAminus -102.5, -37.51 -98.26, 136.29 -130.03, 25.37 293.68, 92.54 -51.9, -36.59 in-in in 8.523 Saltbr-in 2.796 HRD-in -64.86, -55.72 73.4, -5.55 in-in-none SNCiin in-none ActLoopNT-in 3.08 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 3.86 APE9-dihe-in -59.13, 149.03 APE8-dihe-in -86.97, 92.69 APE8-rot-na 29.75 APE67-dihe-in -64.62, -7.75 -51.29, -49.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 9.929 APE9-dist-in 6.448 None PTR1234,PTR1235 PTR1234,PTR1235 XRAY 2.3 0.213 0.24 A 307 297 4 0 0 4 [[1078, 1339]] 1.0 3r7o Homo sapiens TYR_MET_HUMAN TYR 6.8e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3Q6UA P08581 1048 1348 1390.0 AME:50001 Allosteric Inactive DFGin 5.3 15.171 BLBminus -141.8, -165.83 43.31, 48.52 -52.58, 142.95 318.65, 93.03 -67.63, 999.0 in-out in 8.567 Saltbr-out 5.754 HRD-in -70.18, -46.51 72.44, -16.24 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -18.53 APE8-dihe-in -77.28, 65.76 APE8-rot-na 29.07 APE67-dihe-in -73.85, -1.6 -47.31, -44.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.898 None None None XRAY 1.6 0.185 0.214 A 308 281 20 0 0 20 [[1078, 1339]] 1.0 3q6u Homo sapiens TYR_MET_HUMAN TYR 6.8e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3DKCA P08581 1051 1360 1390.0 ATP:60001 ATPlike Inactive DFGin 5.693 13.103 BLBplus -128.11, 162.74 67.51, 17.44 -61.67, 130.17 44.2, 92.69 80.08, -22.94 out-out out 14.083 Saltbr-out 12.836 HRD-in -71.17, -57.45 82.5, -22.81 out-out-out SNCooo out-out ActLoopNT-out 7.739 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -83.24, -9.16 APE9-dihe-in -104.14, 150.23 APE8-dihe-in -75.82, 62.17 APE8-rot-na 30.64 APE67-dihe-in -64.7, -18.65 -61.74, -26.11 APE12-dist-na 18.53 APE11-dist-na 20.199 APE10-dist-na 15.662 APE9-dist-out 9.072 Y1194F,Y1234F,Y1235D None None XRAY 1.52 0.189 0.218 A 317 310 0 0 0 0 [[1078, 1339]] 1.0 3dkc Homo sapiens TYR_MET_HUMAN TYR 8.6e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 2G15A P08581 1046 1346 1390.0 No_ligand No_ligand Inactive DFGin 5.308 14.807 BLBplus -126.95, -156.89 55.44, 45.38 -146.85, 161.09 77.95, 91.4 56.77, -133.56 out-out out 12.828 Saltbr-out 9.792 HRD-in -76.71, -50.46 77.7, -17.49 out-out-in SNCooi out-in ActLoopNT-out 10.595 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.17, 130.97 APE9-dihe-in -100.06, 147.13 APE8-dihe-in -78.36, 70.19 APE8-rot-na 37.37 APE67-dihe-in -76.51, 3.63 -46.75, -47.03 APE12-dist-na 19.695 APE11-dist-na 15.425 APE10-dist-na 18.424 APE9-dist-in 7.346 None None None XRAY 2.15 0.234 0.259 A 318 301 0 0 0 0 [[1078, 1339]] 1.0 2g15 Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 1R1WA P08581 1050 1360 1390.0 No_ligand No_ligand Inactive DFGin 6.39 14.656 BLBplus -130.27, -160.33 52.67, 47.82 -146.19, 163.95 73.82, 94.67 55.34, -136.67 out-out out 13.083 Saltbr-out 8.828 HRD-in -65.43, -49.53 76.09, -18.82 out-out-none SNCoon out-none ActLoopNT-out 11.48 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 149.17 APE8-dihe-in -80.54, 64.23 APE8-rot-na 34.06 APE67-dihe-in -75.31, -10.28 -59.25, -30.26 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.438 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 1.8 0.174 0.204 A 312 287 24 0 0 14 [[1078, 1339]] 1.0 1r1w Homo sapiens TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8AU3A P08581 1052 1349 1390.0 3E8:1401 Type1 Inactive DFGin 5.684 14.29 BLBplus -124.89, -160.9 56.91, 51.79 -144.24, 164.35 65.96, 84.2 62.67, -127.3 out-out out 12.107 Saltbr-out 10.728 HRD-in -74.56, -50.99 74.86, 1.96 out-out-out SNCooo out-out ActLoopNT-out 10.759 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -67.06 APE8-dihe-out -64.75, -14.77 APE8-rot-na 35.69 APE67-dihe-in -73.18, -9.04 -40.0, -46.69 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 10.271 Y1234E,Y1235E None None XRAY 2.26 0.198 0.24 A 299 285 13 0 0 13 [[1078, 1339]] 1.0 8au3 Homo sapiens TYR_MET_HUMAN TYR 4.5e-91 310.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8AU3B P08581 1056 1349 1390.0 3E8:1401 Type1 Inactive DFGin 5.496 14.473 BLBplus -125.67, -163.77 56.96, 51.67 -147.0, 169.32 67.61, 95.69 59.55, -126.73 out-out out 15.391 Saltbr-out 16.785 HRD-in -71.6, -51.19 76.55, 0.05 out-out-out SNCooo out-out ActLoopNT-out 10.966 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -66.77 APE8-dihe-out -65.4, -13.15 APE8-rot-na 35.16 APE67-dihe-in -76.94, -3.51 -35.23, -49.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 10.331 Y1234E,Y1235E None None XRAY 2.26 0.198 0.24 B 299 281 13 0 0 13 [[1078, 1339]] 1.0 8au3 Homo sapiens TYR_MET_HUMAN TYR 4.5e-91 310.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8AU5A P08581 1067 1346 1390.0 3E8:1401 Type1 Inactive DFGin 5.707 14.374 BLBplus -119.33, -165.19 60.98, 56.2 -152.49, 146.81 74.85, 101.87 68.18, -123.4 out-out out 15.336 Saltbr-out 11.537 HRD-in -65.68, -49.98 78.74, -13.11 out-out-in SNCooi out-in ActLoopNT-out 10.8 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.2, 134.11 APE9-dihe-in -112.02, 144.15 APE8-dihe-in -87.51, 76.24 APE8-rot-na 34.54 APE67-dihe-in -68.65, -16.74 -55.51, -46.08 APE12-dist-na 20.917 APE11-dist-na 16.445 APE10-dist-na 17.773 APE9-dist-in 7.409 F1200I None None XRAY 2.72 0.239 0.278 A 299 265 15 0 0 2 [[1078, 1339]] 1.0 8au5 Homo sapiens TYR_MET_HUMAN TYR 1.6e-91 312.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8AW1A P08581 1066 1345 1390.0 3E8:1401 Type1 Inactive DFGin 5.295 13.933 BLBplus -124.71, -163.84 60.77, 51.89 -150.77, 158.45 69.7, 88.83 60.72, -129.97 out-out out 14.414 Saltbr-out 12.19 HRD-in -71.16, -55.41 80.21, -13.77 out-out-none SNCoon out-none ActLoopNT-out 10.771 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 138.91 APE9-dihe-in -126.21, 148.9 APE8-dihe-in -85.84, 71.21 APE8-rot-na 27.14 APE67-dihe-in -72.93, -13.12 -55.01, -33.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 18.233 APE9-dist-in 7.208 Y1235D None None XRAY 2.14 0.218 0.241 A 299 263 17 0 0 8 [[1078, 1339]] 1.0 8aw1 Homo sapiens TYR_MET_HUMAN TYR 3.4e-91 311.1 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8AW1B P08581 1064 1345 1390.0 3E8:1401 Type1 Inactive DFGin 5.302 14.15 BLBplus -123.92, -163.21 58.0, 49.54 -149.17, 156.39 75.23, 94.55 65.41, -133.45 out-out out 14.898 Saltbr-out 12.507 HRD-in -69.21, -52.41 76.89, -7.96 out-out-in SNCooi out-in ActLoopNT-out 10.535 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.96, 136.97 APE9-dihe-in -126.46, 148.09 APE8-dihe-in -85.21, 69.6 APE8-rot-na 28.63 APE67-dihe-in -72.96, -12.49 -53.88, -33.35 APE12-dist-na 999.0 APE11-dist-na 18.063 APE10-dist-na 18.136 APE9-dist-in 7.261 Y1235D None None XRAY 2.14 0.218 0.241 B 299 264 18 0 0 8 [[1078, 1339]] 1.0 8aw1 Homo sapiens TYR_MET_HUMAN TYR 3.4e-91 311.1 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4KNBA P08581 1064 1344 1390.0 1RU:1401 Type1 Inactive DFGin 7.396 15.201 BLBplus -152.82, -179.39 62.03, 58.92 -149.54, 152.74 61.81, 86.02 75.53, -138.63 out-out out 14.197 Saltbr-out 10.579 HRD-in -69.86, -46.71 77.62, -9.35 out-out-in SNCooi out-in ActLoopNT-out 10.903 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.7, 119.58 APE9-dihe-in -122.47, 151.86 APE8-dihe-in -86.64, 71.14 APE8-rot-na 34.49 APE67-dihe-in -76.94, -9.0 -56.56, -34.11 APE12-dist-na 20.969 APE11-dist-na 17.384 APE10-dist-na 17.285 APE9-dist-in 7.257 None None None XRAY 2.4 0.241 0.288 A 287 273 8 0 0 0 [[1078, 1339]] 1.0 4knb Homo sapiens TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4KNBB P08581 1067 1346 1390.0 1RU:1401 Type1 Inactive DFGin 6.633 14.923 BLBplus -140.56, -158.55 49.94, 50.72 -140.14, 167.67 69.36, 88.3 68.61, -122.44 out-out out 12.979 Saltbr-out 11.834 HRD-in -70.12, -52.42 79.03, -19.75 out-out-none SNCoon out-none ActLoopNT-out 10.575 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.8 APE8-dihe-in -88.71, 82.26 APE8-rot-na 34.66 APE67-dihe-in -82.92, -0.08 -66.31, -34.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.226 None None None XRAY 2.4 0.241 0.288 B 287 256 24 0 0 7 [[1078, 1339]] 1.0 4knb Homo sapiens TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4KNBC P08581 1060 1346 1390.0 1RU:1401 Type1 Inactive DFGin 7.512 15.058 BLBplus -156.58, -177.82 66.97, 40.82 -135.01, 151.51 62.44, 86.93 79.96, -136.08 out-out out 14.073 Saltbr-out 12.236 HRD-in -72.87, -52.33 81.95, -23.66 out-out-in SNCooi out-in ActLoopNT-out 10.826 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -91.48, 116.68 APE9-dihe-in -120.39, 142.28 APE8-dihe-in -82.11, 77.71 APE8-rot-na 33.0 APE67-dihe-in -75.83, -4.77 -60.57, -35.58 APE12-dist-na 20.424 APE11-dist-na 16.911 APE10-dist-na 16.769 APE9-dist-in 7.267 None None None XRAY 2.4 0.241 0.288 C 287 271 16 0 0 2 [[1078, 1339]] 1.0 4knb Homo sapiens TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4KNBD P08581 1064 1346 1390.0 1RU:1401 Type1 Inactive DFGin 6.986 14.712 BLBplus -149.29, -177.18 65.69, 42.15 -130.43, 146.51 58.33, 85.64 71.37, -113.33 out-out out 13.073 Saltbr-out 11.475 HRD-in -71.74, -48.48 75.48, -1.19 out-out-none SNCoon out-none ActLoopNT-out 10.032 ActLoopCT-none TYR APEdihe_nnnan APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-na 999.0 APE67-dihe-none -71.11, -17.0 999.0, -33.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.241 0.288 D 287 247 36 0 0 17 [[1078, 1339]] 1.0 4knb Homo sapiens TYR_MET_HUMAN TYR 5.3e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4R1VA P08581 1055 1345 1390.0 3E8:1401 Type1 Inactive DFGin 6.851 15.131 BLBplus -128.85, -160.46 55.61, 46.43 -145.43, 164.26 73.06, 94.72 59.68, -132.26 out-out out 13.914 Saltbr-out 11.075 HRD-in -72.84, -48.56 75.96, -10.9 out-out-in SNCooi out-in ActLoopNT-out 10.449 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.25, 114.51 APE9-dihe-in -113.76, 127.94 APE8-dihe-in -81.67, 70.95 APE8-rot-na 30.91 APE67-dihe-in -76.37, -2.92 -53.11, -41.22 APE12-dist-na 20.098 APE11-dist-na 17.696 APE10-dist-na 15.864 APE9-dist-in 7.088 None None None XRAY 1.2 0.146 0.176 A 291 289 2 0 0 0 [[1078, 1339]] 1.0 4r1v Homo sapiens TYR_MET_HUMAN TYR 5.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 2WD1A P08581 1055 1346 1390.0 ZZY:2347 Type1 Inactive DFGin 6.715 15.354 BLBplus -130.22, -166.88 64.65, 49.75 -149.56, 164.94 68.51, 95.8 63.64, -135.28 out-out out 13.824 Saltbr-out 12.347 HRD-in -74.73, -45.22 71.7, -7.55 out-out-in SNCooi out-in ActLoopNT-out 10.742 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.57, 113.21 APE9-dihe-in -115.76, 119.45 APE8-dihe-in -78.13, 71.2 APE8-rot-na 32.53 APE67-dihe-in -78.85, -3.09 -55.46, -34.61 APE12-dist-na 20.5 APE11-dist-na 17.629 APE10-dist-na 15.642 APE9-dist-in 7.141 None None None XRAY 2.0 0.212 0.265 A 292 289 3 0 0 0 [[1078, 1339]] 1.0 2wd1 Homo sapiens TYR_MET_HUMAN TYR 5.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4R1YA P08581 1062 1346 1390.0 3EH:1401 Type1 Inactive DFGin 5.389 14.32 BLBplus -132.11, -159.52 51.31, 47.36 -144.5, 163.73 73.25, 87.93 64.4, -132.62 out-out out 15.877 Saltbr-out 12.711 HRD-in -64.58, -54.45 81.56, -8.87 out-out-in SNCooi out-in ActLoopNT-out 10.511 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.36, 113.99 APE9-dihe-in -111.97, 135.44 APE8-dihe-in -80.5, 71.16 APE8-rot-na 34.01 APE67-dihe-in -79.68, -2.29 -56.23, -33.98 APE12-dist-na 20.296 APE11-dist-na 17.153 APE10-dist-na 16.547 APE9-dist-in 7.184 None None None XRAY 2.0 0.182 0.238 A 292 265 20 0 0 2 [[1078, 1339]] 1.0 4r1y Homo sapiens TYR_MET_HUMAN TYR 5.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3F66A P08581 1052 1349 1390.0 IHX:1 Type1 Inactive DFGin 7.263 14.857 BLBplus -128.75, -158.89 48.95, 46.34 -144.78, 166.08 75.55, 97.31 63.29, -132.51 out-out out 13.574 Saltbr-out 11.349 HRD-in -64.61, -55.36 78.27, -14.18 out-out-in SNCooi out-in ActLoopNT-out 10.594 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.3, 122.4 APE9-dihe-in -117.84, 131.22 APE8-dihe-in -81.93, 72.25 APE8-rot-na 30.12 APE67-dihe-in -81.86, -2.13 -59.58, -32.42 APE12-dist-na 999.0 APE11-dist-na 19.318 APE10-dist-na 17.265 APE9-dist-in 7.512 None None None XRAY 1.4 0.168 0.225 A 298 288 10 0 0 5 [[1078, 1339]] 1.0 3f66 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3F66B P08581 1062 1349 1390.0 IHX:2 Type1 Inactive DFGin 6.17 14.857 BLBplus -124.32, -152.82 48.56, 45.67 -143.8, 164.53 77.46, 95.64 58.79, -132.52 out-out out 12.635 Saltbr-out 10.008 HRD-in -70.66, -50.0 82.15, -19.93 out-out-in SNCooi out-in ActLoopNT-out 10.506 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.09, 122.26 APE9-dihe-in -125.33, 130.32 APE8-dihe-in -82.56, 66.62 APE8-rot-na 32.5 APE67-dihe-in -73.35, -5.99 -57.96, -33.87 APE12-dist-na 999.0 APE11-dist-na 18.786 APE10-dist-na 16.529 APE9-dist-in 7.5 None None None XRAY 1.4 0.168 0.225 B 298 269 19 0 0 6 [[1078, 1339]] 1.0 3f66 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B3QA P08581 1055 1344 1390.0 SV5:1401 Type1 Inactive DFGin 6.832 15.773 BLBplus -131.15, -158.97 56.06, 42.1 -142.47, 159.33 72.23, 89.52 55.71, -134.93 out-out out 13.378 Saltbr-out 11.858 HRD-in -71.71, -52.43 80.21, -12.26 out-out-none SNCoon out-none ActLoopNT-out 11.132 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 59.63 APE8-rot-na 31.05 APE67-dihe-in -75.78, -2.08 -59.63, -33.45 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.75 0.172 0.192 A 299 283 7 0 0 7 [[1078, 1339]] 1.0 7b3q Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B3TA P08581 1062 1344 1390.0 SVK:1401 Type1 Inactive DFGin 6.519 15.327 BLBplus -120.02, -162.4 55.57, 41.79 -137.77, 159.0 68.39, 89.6 58.57, -125.45 out-none out 13.689 Saltbr-none 999.0 HRD-in -66.03, -59.34 82.42, -20.25 none-out-none SNCnon out-none ActLoopNT-out 10.981 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.08 APE8-dihe-in -83.51, 64.45 APE8-rot-na 32.74 APE67-dihe-in -77.89, -3.69 -51.47, -31.87 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.364 None None None XRAY 2.23 0.213 0.261 A 299 261 22 0 0 8 [[1078, 1339]] 1.0 7b3t Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B3VA P08581 1057 1344 1390.0 SWB:1401 Type1 Inactive DFGin 6.716 15.052 BLBplus -126.23, -152.04 48.88, 44.58 -143.57, 160.23 70.62, 87.46 59.4, -135.97 out-out out 12.514 Saltbr-out 11.795 HRD-in -62.92, -51.88 77.76, -15.35 out-out-none SNCoon out-none ActLoopNT-out 11.439 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 136.89 APE8-dihe-in -89.06, 65.51 APE8-rot-na 32.11 APE67-dihe-in -77.53, -1.68 -55.38, -33.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.586 None None None XRAY 1.93 0.226 0.248 A 299 274 14 0 0 14 [[1078, 1339]] 1.0 7b3v Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B3WA P08581 1067 1344 1390.0 SVH:1402 Type1 Inactive DFGin 5.387 13.871 BLBplus -131.54, -154.8 46.8, 51.05 -143.29, 166.34 73.88, 93.09 55.12, -131.3 none-none none 999.0 Saltbr-none 999.0 HRD-in -71.86, -48.55 76.55, -13.24 none-out-in SNCnoi out-in ActLoopNT-out 10.691 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.57, 125.95 APE9-dihe-in -121.38, 106.22 APE8-dihe-in -80.21, 79.23 APE8-rot-na 27.53 APE67-dihe-in -82.98, -4.93 -45.47, -41.85 APE12-dist-na 17.77 APE11-dist-na 16.633 APE10-dist-na 14.553 APE9-dist-in 6.661 None None None XRAY 2.02 0.234 0.261 A 299 259 19 0 0 0 [[1078, 1339]] 1.0 7b3w Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B3ZA P08581 1055 1344 1390.0 SV8:1402 Type1 Inactive DFGin 6.58 14.893 BLBplus -126.68, -152.67 54.96, 44.35 -145.25, 158.18 71.33, 93.43 60.81, -133.47 out-out out 12.488 Saltbr-out 9.584 HRD-in -68.18, -50.86 78.29, -16.82 out-out-none SNCoon out-none ActLoopNT-out 11.274 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 56.56 APE8-rot-na 31.04 APE67-dihe-in -77.58, -5.34 -58.45, -27.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.8 0.194 0.215 A 299 277 13 0 0 10 [[1078, 1339]] 1.0 7b3z Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B40A P08581 1055 1346 1390.0 SWN:1401 Type1 Inactive DFGin 6.79 14.911 BLBplus -121.15, -157.08 57.45, 51.11 -151.5, 157.52 69.47, 91.73 61.68, -131.87 out-out out 12.671 Saltbr-out 10.542 HRD-in -64.67, -50.63 76.39, -16.73 out-out-none SNCoon out-none ActLoopNT-out 11.24 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 55.67 APE8-rot-na 31.0 APE67-dihe-in -75.78, 0.12 -57.64, -33.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.76 0.198 0.232 A 299 279 13 0 0 10 [[1078, 1339]] 1.0 7b40 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B41A P08581 1055 1346 1390.0 SWK:1401 Type1 Inactive DFGin 6.436 15.448 BLBplus -124.18, -158.65 59.39, 42.13 -146.22, 161.88 71.86, 91.85 59.6, -131.08 out-out out 13.229 Saltbr-out 12.226 HRD-in -68.34, -50.78 73.99, -12.52 out-out-none SNCoon out-none ActLoopNT-out 11.136 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.12 APE8-dihe-in -81.62, 71.84 APE8-rot-na 32.68 APE67-dihe-in -74.71, -7.29 -62.43, -28.21 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.609 None None None XRAY 1.97 0.198 0.233 A 299 281 11 0 0 8 [[1078, 1339]] 1.0 7b41 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B42A P08581 1055 1344 1390.0 SW8:1401 Type1 Inactive DFGin 6.437 15.377 BLBplus -131.8, -155.43 53.21, 43.89 -142.75, 162.05 73.24, 92.06 57.88, -128.49 out-out out 13.148 Saltbr-out 9.811 HRD-in -67.34, -48.52 73.85, -12.1 out-out-none SNCoon out-none ActLoopNT-out 11.133 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.12 APE8-dihe-in -83.17, 71.94 APE8-rot-na 32.5 APE67-dihe-in -76.0, -4.88 -61.93, -28.32 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.478 None None None XRAY 1.8 0.203 0.225 A 299 279 11 0 0 8 [[1078, 1339]] 1.0 7b42 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B43A P08581 1055 1344 1390.0 SW5:1401 Type1 Inactive DFGin 6.725 15.384 BLBplus -126.09, -157.56 60.31, 47.69 -153.83, 159.32 70.69, 88.14 59.9, -130.71 out-out out 12.692 Saltbr-out 10.243 HRD-in -65.42, -49.31 73.61, -13.55 out-out-none SNCoon out-none ActLoopNT-out 11.15 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 60.98 APE8-rot-na 29.69 APE67-dihe-in -76.44, -8.08 -59.13, -26.96 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.87 0.203 0.248 A 299 277 13 0 0 10 [[1078, 1339]] 1.0 7b43 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B43B P08581 1055 1346 1390.0 SW5:1401 Type1 Inactive DFGin 6.236 15.323 BLBplus -125.04, -160.72 66.1, 34.55 -135.49, 162.98 72.55, 100.65 59.58, -127.12 out-out out 12.988 Saltbr-out 10.686 HRD-in -68.52, -55.71 82.35, -23.91 out-out-none SNCoon out-none ActLoopNT-out 11.179 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 39.26 APE8-rot-na 32.26 APE67-dihe-in -72.77, -5.06 -51.67, -38.14 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.87 0.203 0.248 B 299 278 14 0 0 10 [[1078, 1339]] 1.0 7b43 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7B44A P08581 1055 1346 1390.0 SVT:1401 Type1 Inactive DFGin 7.175 15.058 BLBplus -129.18, -161.23 56.95, 43.1 -145.51, 165.59 71.68, 95.88 55.78, -129.36 out-out out 12.739 Saltbr-out 10.066 HRD-in -67.86, -52.32 77.82, -15.46 out-out-none SNCoon out-none ActLoopNT-out 11.011 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 53.85 APE8-rot-na 33.36 APE67-dihe-in -75.94, -5.45 -57.41, -32.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.76 0.18 0.208 A 299 282 10 0 0 7 [[1078, 1339]] 1.0 7b44 Homo sapiens TYR_MET_HUMAN TYR 6.1e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 2WGJA P08581 1052 1345 1390.0 VGH:2346 Type1 Inactive DFGin 5.419 14.21 BLBplus -135.65, -156.26 47.26, 45.25 -135.61, 161.65 71.89, 90.85 65.05, -128.27 out-out out 14.431 Saltbr-out 12.345 HRD-in -73.92, -55.59 85.56, -13.18 out-out-in SNCooi out-in ActLoopNT-out 10.89 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -55.61, 121.54 APE9-dihe-in -139.09, 151.01 APE8-dihe-in -79.04, 70.35 APE8-rot-na 28.98 APE67-dihe-in -76.22, -0.44 -56.63, -35.75 APE12-dist-na 22.704 APE11-dist-na 17.972 APE10-dist-na 17.34 APE9-dist-in 7.149 None None None XRAY 2.0 0.215 0.232 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 2wgj Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 2WKMA P08581 1059 1345 1390.0 PFY:2345 Type1 Inactive DFGin 5.71 14.639 BLBplus -142.49, -164.26 57.54, 44.85 -136.55, 165.51 66.62, 94.71 61.32, -132.62 out-out out 14.596 Saltbr-out 12.863 HRD-in -83.33, -52.67 82.5, -15.17 out-out-in SNCooi out-in ActLoopNT-out 10.979 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.21, 106.53 APE9-dihe-in -122.06, 155.91 APE8-dihe-in -79.28, 64.7 APE8-rot-na 31.75 APE67-dihe-in -79.76, -1.27 -59.82, -29.2 APE12-dist-na 22.882 APE11-dist-na 18.107 APE10-dist-na 17.777 APE9-dist-in 7.327 None None None XRAY 2.2 0.218 0.275 A 306 287 0 0 0 0 [[1078, 1339]] 1.0 2wkm Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3ZBXA P08581 1059 1345 1390.0 6XE:2345 Type1 Inactive DFGin 5.12 14.193 BLBplus -133.53, -157.04 42.72, 56.92 -148.81, 166.27 77.97, 91.1 53.49, -129.22 out-out out 14.763 Saltbr-out 12.078 HRD-in -79.72, -52.28 81.84, -11.2 out-out-in SNCooi out-in ActLoopNT-out 10.825 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.5, 113.68 APE9-dihe-in -132.32, 152.54 APE8-dihe-in -79.14, 72.88 APE8-rot-na 29.52 APE67-dihe-in -87.19, -2.39 -66.55, -21.23 APE12-dist-na 22.906 APE11-dist-na 18.11 APE10-dist-na 17.397 APE9-dist-in 7.36 None None None XRAY 2.2 0.179 0.237 A 306 283 4 0 0 0 [[1078, 1339]] 1.0 3zbx Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3ZC5A P08581 1052 1345 1390.0 W9Z:2345 Type1 Inactive DFGin 5.372 14.264 BLBplus -131.02, -159.69 45.54, 54.39 -146.48, 156.9 75.4, 87.57 59.1, -130.23 out-out out 14.903 Saltbr-out 12.537 HRD-in -80.37, -53.07 84.31, -5.5 out-out-in SNCooi out-in ActLoopNT-out 10.711 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -59.62, 118.89 APE9-dihe-in -135.45, 149.7 APE8-dihe-in -76.5, 67.7 APE8-rot-na 27.79 APE67-dihe-in -84.21, -3.17 -61.58, -26.66 APE12-dist-na 23.107 APE11-dist-na 18.375 APE10-dist-na 17.446 APE9-dist-in 7.352 None None None XRAY 2.2 0.204 0.256 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 3zc5 Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3ZCLA P08581 1052 1345 1390.0 5TF:1 Type1 Inactive DFGin 5.341 14.033 BLBplus -130.37, -159.34 48.43, 53.41 -147.61, 165.56 74.15, 92.01 59.61, -131.84 out-out out 14.636 Saltbr-out 12.785 HRD-in -76.45, -51.81 82.5, -13.86 out-out-in SNCooi out-in ActLoopNT-out 10.735 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.5, 109.91 APE9-dihe-in -127.18, 152.9 APE8-dihe-in -78.54, 68.73 APE8-rot-na 30.54 APE67-dihe-in -82.79, -0.65 -60.11, -28.04 APE12-dist-na 22.937 APE11-dist-na 18.131 APE10-dist-na 17.771 APE9-dist-in 7.357 None None None XRAY 1.4 0.194 0.211 A 306 291 3 0 0 0 [[1078, 1339]] 1.0 3zcl Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3ZXZA P08581 1052 1345 1390.0 KRW:2345 Type1 Inactive DFGin 5.343 14.082 BLBplus -135.73, -162.15 50.43, 49.79 -141.07, 164.71 71.86, 91.49 60.06, -132.86 out-out out 14.83 Saltbr-out 12.413 HRD-in -72.98, -56.4 84.76, -11.76 out-out-in SNCooi out-in ActLoopNT-out 10.829 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.31, 115.77 APE9-dihe-in -134.5, 149.99 APE8-dihe-in -77.74, 66.2 APE8-rot-na 31.4 APE67-dihe-in -82.4, 0.31 -58.66, -28.33 APE12-dist-na 23.051 APE11-dist-na 18.283 APE10-dist-na 17.596 APE9-dist-in 7.379 None None None XRAY 1.8 0.185 0.221 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 3zxz Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3ZZEA P08581 1059 1345 1390.0 6XP:2345 Type1 Inactive DFGin 5.344 13.872 BLBplus -124.39, -164.42 52.84, 52.22 -144.64, 167.08 70.9, 89.5 57.01, -128.68 out-out out 14.665 Saltbr-out 12.449 HRD-in -75.38, -48.62 80.64, -12.79 out-out-in SNCooi out-in ActLoopNT-out 10.476 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.32, 110.44 APE9-dihe-in -128.02, 154.15 APE8-dihe-in -79.41, 68.67 APE8-rot-na 30.48 APE67-dihe-in -82.56, 0.41 -59.17, -30.92 APE12-dist-na 22.788 APE11-dist-na 17.994 APE10-dist-na 17.776 APE9-dist-in 7.366 None None None XRAY 1.87 0.196 0.226 A 306 287 0 0 0 0 [[1078, 1339]] 1.0 3zze Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4AOIA P08581 1052 1344 1390.0 4K0:2345 Type1 Inactive DFGin 5.261 14.02 BLBplus -129.93, -161.21 48.66, 52.43 -145.16, 163.98 75.34, 90.8 58.17, -131.76 out-out out 14.801 Saltbr-out 12.571 HRD-in -74.56, -53.23 81.11, -12.36 out-out-in SNCooi out-in ActLoopNT-out 10.798 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.22, 118.1 APE9-dihe-in -136.02, 153.34 APE8-dihe-in -77.45, 67.07 APE8-rot-na 29.7 APE67-dihe-in -82.77, -0.39 -59.05, -28.87 APE12-dist-na 22.904 APE11-dist-na 18.176 APE10-dist-na 17.433 APE9-dist-in 7.302 None None None XRAY 1.9 0.173 0.214 A 306 289 4 0 0 0 [[1078, 1339]] 1.0 4aoi Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4AP7A P08581 1052 1345 1390.0 F47:2345 Type1 Inactive DFGin 5.33 13.973 BLBplus -138.21, -157.46 42.59, 55.52 -147.39, 165.76 73.46, 94.54 64.47, -135.14 out-out out 14.61 Saltbr-out 12.353 HRD-in -75.32, -50.89 81.42, -14.36 out-out-in SNCooi out-in ActLoopNT-out 10.84 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -65.24, 106.32 APE9-dihe-in -126.12, 153.32 APE8-dihe-in -76.65, 65.8 APE8-rot-na 31.12 APE67-dihe-in -83.64, 0.36 -57.49, -29.42 APE12-dist-na 22.755 APE11-dist-na 17.934 APE10-dist-na 17.549 APE9-dist-in 7.331 None None None XRAY 1.8 0.191 0.214 A 306 290 4 0 0 0 [[1078, 1339]] 1.0 4ap7 Homo sapiens TYR_MET_HUMAN TYR 6.7e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 6SDEA P08581 1068 1346 1390.0 V0L:1401 Type1 Inactive DFGin 5.667 14.258 BLBplus -119.68, -150.47 45.1, 45.32 -137.22, 165.05 73.76, 86.18 57.67, -122.8 out-out out 12.938 Saltbr-out 14.043 HRD-in -63.81, -56.75 81.6, -9.64 out-out-in SNCooi out-in ActLoopNT-out 10.868 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -89.68, 108.89 APE9-dihe-in -113.03, 135.7 APE8-dihe-in -89.2, 66.09 APE8-rot-na 29.11 APE67-dihe-in -72.7, -11.89 -48.71, -38.04 APE12-dist-na 21.428 APE11-dist-na 18.208 APE10-dist-na 16.549 APE9-dist-in 7.37 None None None XRAY 2.49 0.206 0.273 A 309 268 11 0 0 0 [[1078, 1339]] 1.0 6sde Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7Y4TA P08581 1063 1345 1390.0 I90:1401 Type1 Inactive DFGin 5.023 14.284 BLBplus -124.58, -158.37 55.95, 54.1 -154.01, 158.71 78.56, 97.12 63.89, -132.14 out-none out 15.195 Saltbr-none 999.0 HRD-in -78.32, -47.01 69.41, -2.23 none-out-in SNCnoi out-in ActLoopNT-out 10.674 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.01, 118.18 APE9-dihe-in -113.5, 113.09 APE8-dihe-in -81.35, 89.51 APE8-rot-na 28.65 APE67-dihe-in -80.22, 3.63 -53.84, -52.52 APE12-dist-na 17.236 APE11-dist-na 17.468 APE10-dist-na 14.752 APE9-dist-in 6.875 None None None XRAY 2.16 0.216 0.251 A 309 281 2 0 0 0 [[1078, 1339]] 1.0 7y4t Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7Y4UA P08581 1061 1344 1390.0 I94:1401 Type1 Inactive DFGin 5.011 14.109 BLBplus -122.9, -159.94 57.56, 55.67 -154.79, 156.13 77.75, 94.81 65.91, -133.04 out-out out 15.171 Saltbr-out 14.231 HRD-out -102.1, 85.21 -61.9, -6.95 out-out-in SNCooi out-in ActLoopNT-out 10.685 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -100.87, 119.34 APE9-dihe-in -113.64, 116.39 APE8-dihe-in -76.69, 90.17 APE8-rot-na 26.73 APE67-dihe-in -84.74, 7.32 -56.75, -46.15 APE12-dist-na 17.249 APE11-dist-na 17.28 APE10-dist-na 14.971 APE9-dist-in 7.0 None None None XRAY 2.26 0.24 0.278 A 309 281 3 0 0 0 [[1078, 1339]] 1.0 7y4u Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8GVJA P08581 1060 1344 1390.0 KGL:1401 Type1 Inactive DFGin 5.11 14.333 BLBplus -124.62, -159.68 55.58, 59.15 -155.79, 162.16 77.73, 91.46 64.79, -131.96 out-out out 14.78 Saltbr-out 13.973 HRD-in -76.06, -51.5 83.84, -11.14 out-out-in SNCooi out-in ActLoopNT-out 10.985 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.13, 112.88 APE9-dihe-in -113.43, 113.57 APE8-dihe-in -79.76, 93.91 APE8-rot-na 27.28 APE67-dihe-in -81.42, 13.42 -58.79, -51.95 APE12-dist-na 18.793 APE11-dist-na 17.469 APE10-dist-na 15.018 APE9-dist-in 7.02 None None None XRAY 2.71 0.221 0.262 A 309 285 0 0 0 0 [[1078, 1339]] 1.0 8gvj Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8K78A P08581 1048 1345 1390.0 IYC:1401 Type1 Inactive DFGin 5.279 14.37 BLBplus -137.76, -160.13 53.31, 44.71 -142.62, 155.7 79.32, 100.58 65.31, -134.82 out-none out 14.651 Saltbr-none 999.0 HRD-in -77.86, -46.68 52.66, 21.65 none-out-in SNCnoi out-in ActLoopNT-out 10.631 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.34, 117.5 APE9-dihe-in -112.83, 117.81 APE8-dihe-in -78.38, 91.22 APE8-rot-na 27.2 APE67-dihe-in -75.41, 8.19 -65.34, -41.41 APE12-dist-na 17.854 APE11-dist-na 16.52 APE10-dist-na 14.534 APE9-dist-in 6.426 None None None XRAY 2.67 0.244 0.29 A 309 298 0 0 0 0 [[1078, 1339]] 1.0 8k78 Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 9IVBA P08581 1040 1344 1390.0 A1L3A:1401 Type1 Inactive DFGin 5.445 13.892 BLBplus -135.57, -160.44 57.93, 42.99 -140.54, 145.93 73.22, 97.74 72.46, -130.62 out-out out 14.035 Saltbr-out 14.671 HRD-in -68.9, -37.7 81.17, -14.77 out-out-in SNCooi out-in ActLoopNT-out 10.51 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -104.97, 125.97 APE9-dihe-in -120.0, 114.55 APE8-dihe-in -86.52, 80.12 APE8-rot-na 4.22 APE67-dihe-in -65.25, -14.21 -56.14, -42.02 APE12-dist-na 17.521 APE11-dist-na 16.802 APE10-dist-na 14.316 APE9-dist-in 7.123 None None None XRAY 2.35 0.283 0.273 A 309 302 3 0 0 0 [[1078, 1339]] 1.0 9ivb Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 9IVBB P08581 1045 1344 1390.0 A1L3A:1401 Type1 Inactive DFGin 5.18 14.3 BLBplus -124.93, -159.59 53.11, 55.95 -153.33, 151.13 76.29, 94.39 69.12, -130.38 out-out out 14.992 Saltbr-out 13.201 HRD-in -71.02, -54.88 83.43, -14.37 out-out-in SNCooi out-in ActLoopNT-out 10.476 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.51, 120.57 APE9-dihe-in -121.21, 114.93 APE8-dihe-in -85.2, 88.99 APE8-rot-na 28.75 APE67-dihe-in -90.92, 1.7 -64.46, -35.79 APE12-dist-na 17.431 APE11-dist-na 17.105 APE10-dist-na 14.191 APE9-dist-in 7.193 None None None XRAY 2.35 0.283 0.273 B 309 294 6 0 0 0 [[1078, 1339]] 1.0 9ivb Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3I5NA P08581 1052 1346 1390.0 B2D:1 Type1 Inactive DFGin 6.038 14.541 BLBplus -127.28, -154.19 49.83, 50.79 -143.8, 160.7 74.39, 92.8 63.42, -123.71 out-out out 13.617 Saltbr-out 11.311 HRD-in -72.82, -46.99 80.85, -20.31 out-out-none SNCoon out-none ActLoopNT-out 10.72 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 98.91 APE9-dihe-in -107.74, 144.54 APE8-dihe-in -82.26, 63.33 APE8-rot-na 31.79 APE67-dihe-in -74.62, -6.09 -48.49, -39.28 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 17.049 APE9-dist-in 7.337 None None None XRAY 2.0 0.227 0.267 A 309 280 15 0 0 5 [[1078, 1339]] 1.0 3i5n Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4DEGA P08581 1052 1346 1390.0 0JJ:1401 Type1 Inactive DFGin 6.033 14.383 BLBplus -127.22, -154.54 52.1, 48.24 -142.59, 163.7 71.45, 91.63 63.02, -129.14 out-out out 13.271 Saltbr-out 11.67 HRD-in -71.67, -46.99 80.66, -21.62 out-out-in SNCooi out-in ActLoopNT-out 10.688 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.24, 109.16 APE9-dihe-in -113.2, 139.77 APE8-dihe-in -81.91, 65.94 APE8-rot-na 30.64 APE67-dihe-in -74.41, -7.99 -53.82, -35.69 APE12-dist-na 21.598 APE11-dist-na 18.179 APE10-dist-na 17.091 APE9-dist-in 7.395 None None None XRAY 2.0 0.209 0.254 A 309 286 9 0 0 0 [[1078, 1339]] 1.0 4deg Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4DEHA P08581 1053 1346 1390.0 0JK:1401 Type1 Inactive DFGin 6.057 14.528 BLBplus -118.77, -152.18 51.36, 47.51 -147.03, 167.71 74.3, 93.14 59.45, -131.99 out-out out 13.613 Saltbr-out 13.801 HRD-in -73.1, -45.26 76.33, -19.08 out-out-in SNCooi out-in ActLoopNT-out 10.5 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -101.33, 113.79 APE9-dihe-in -120.5, 140.09 APE8-dihe-in -82.36, 62.75 APE8-rot-na 30.88 APE67-dihe-in -73.8, -10.21 -48.39, -36.82 APE12-dist-na 21.491 APE11-dist-na 18.11 APE10-dist-na 17.084 APE9-dist-in 7.381 None None None XRAY 2.0 0.208 0.259 A 309 286 8 0 0 0 [[1078, 1339]] 1.0 4deh Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4DEIA P08581 1053 1346 1390.0 0JL:1401 Type1 Inactive DFGin 6.121 14.242 BLBplus -122.34, -157.38 50.75, 53.64 -144.41, 169.13 66.13, 83.8 54.4, -127.42 out-out out 13.32 Saltbr-out 13.84 HRD-in -72.66, -45.49 76.43, -21.33 out-out-in SNCooi out-in ActLoopNT-out 10.602 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -95.14, 102.63 APE9-dihe-in -108.52, 140.65 APE8-dihe-in -82.81, 70.26 APE8-rot-na 30.72 APE67-dihe-in -78.51, -10.8 -58.49, -27.8 APE12-dist-na 21.569 APE11-dist-na 18.042 APE10-dist-na 17.097 APE9-dist-in 7.4 None None None XRAY 2.05 0.224 0.289 A 309 287 7 0 0 0 [[1078, 1339]] 1.0 4dei Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4XMOA P08581 1051 1345 1390.0 46G:1401 Type1 Inactive DFGin 6.061 14.582 BLBplus -129.58, -158.16 50.96, 49.75 -142.1, 164.65 70.02, 93.12 57.3, -130.85 out-out out 13.556 Saltbr-out 13.251 HRD-in -71.94, -50.02 79.17, -15.93 out-out-in SNCooi out-in ActLoopNT-out 10.698 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -89.88, 114.39 APE9-dihe-in -119.44, 138.84 APE8-dihe-in -81.7, 66.87 APE8-rot-na 33.32 APE67-dihe-in -76.96, -5.37 -54.98, -35.22 APE12-dist-na 21.626 APE11-dist-na 18.238 APE10-dist-na 17.102 APE9-dist-in 7.397 None None None XRAY 1.75 0.189 0.238 A 309 289 6 0 0 0 [[1078, 1339]] 1.0 4xmo Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4XYFA P08581 1052 1346 1390.0 44X:1401 Type1 Inactive DFGin 5.955 14.467 BLBplus -129.22, -158.24 51.22, 48.43 -138.73, 167.76 72.05, 90.4 55.51, -128.08 out-out out 13.426 Saltbr-out 12.027 HRD-in -70.98, -46.03 78.03, -20.86 out-out-in SNCooi out-in ActLoopNT-out 10.726 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.7, 109.11 APE9-dihe-in -116.15, 139.41 APE8-dihe-in -78.81, 66.81 APE8-rot-na 36.31 APE67-dihe-in -74.32, -11.26 -55.76, -34.2 APE12-dist-na 21.592 APE11-dist-na 18.328 APE10-dist-na 17.099 APE9-dist-in 7.342 None None None XRAY 1.85 0.188 0.236 A 309 290 5 0 0 0 [[1078, 1339]] 1.0 4xyf Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5EYCA P08581 1053 1345 1390.0 5SZ:1401 Type1 Inactive DFGin 6.049 14.392 BLBplus -124.88, -162.56 54.84, 49.52 -141.18, 168.05 68.53, 92.9 54.54, -130.14 out-out out 13.457 Saltbr-out 13.828 HRD-in -71.93, -50.47 80.12, -18.14 out-out-in SNCooi out-in ActLoopNT-out 10.643 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.28, 111.88 APE9-dihe-in -115.86, 143.23 APE8-dihe-in -81.81, 66.86 APE8-rot-na 33.4 APE67-dihe-in -76.11, -9.46 -54.59, -33.33 APE12-dist-na 21.655 APE11-dist-na 18.189 APE10-dist-na 17.234 APE9-dist-in 7.424 None None None XRAY 1.8 0.195 0.247 A 309 288 5 0 0 0 [[1078, 1339]] 1.0 5eyc Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5EYDA P08581 1052 1348 1390.0 5T1:1401 Type1 Inactive DFGin 6.135 14.363 BLBplus -123.82, -156.55 49.71, 49.92 -139.65, 165.23 70.93, 90.23 56.87, -129.07 out-out out 13.351 Saltbr-out 14.939 HRD-in -69.59, -48.96 78.63, -19.82 out-out-in SNCooi out-in ActLoopNT-out 10.745 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.5, 109.78 APE9-dihe-in -116.31, 141.23 APE8-dihe-in -79.79, 63.19 APE8-rot-na 35.14 APE67-dihe-in -74.55, -9.26 -51.73, -35.89 APE12-dist-na 21.524 APE11-dist-na 18.141 APE10-dist-na 17.07 APE9-dist-in 7.348 None None None XRAY 1.85 0.196 0.249 A 309 289 8 0 0 0 [[1078, 1339]] 1.0 5eyd Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 2RFSA P08581 1067 1346 1390.0 AM8:1 Type1 Inactive DFGin 6.069 13.791 BLBplus -134.84, -164.3 47.97, 50.26 -129.99, 165.29 61.69, 86.55 61.54, -131.37 out-out out 13.021 Saltbr-out 13.367 HRD-in -67.35, -49.82 82.23, -27.14 out-out-in SNCooi out-in ActLoopNT-out 10.393 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -100.22, 107.83 APE9-dihe-in -121.5, 142.78 APE8-dihe-in -78.23, 65.91 APE8-rot-na 30.23 APE67-dihe-in -71.52, -6.3 -48.02, -39.17 APE12-dist-na 20.981 APE11-dist-na 17.387 APE10-dist-na 17.019 APE9-dist-in 7.386 None None None XRAY 2.2 0.226 0.262 A 310 264 16 0 0 2 [[1078, 1339]] 1.0 2rfs Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3CCNA P08581 1055 1346 1390.0 LKG:1 Type1 Inactive DFGin 6.094 14.425 BLBplus -129.45, -153.22 49.92, 50.15 -147.15, 164.18 75.84, 92.59 61.51, -123.83 out-out out 13.227 Saltbr-out 12.591 HRD-in -71.91, -46.5 80.65, -21.52 out-out-in SNCooi out-in ActLoopNT-out 10.633 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.58, 113.44 APE9-dihe-in -120.03, 138.85 APE8-dihe-in -80.52, 67.02 APE8-rot-na 31.14 APE67-dihe-in -74.86, -7.0 -54.1, -35.12 APE12-dist-na 21.706 APE11-dist-na 18.393 APE10-dist-na 17.081 APE9-dist-in 7.312 None None None XRAY 1.9 0.238 0.275 A 310 275 17 0 0 1 [[1078, 1339]] 1.0 3ccn Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3CD8A P08581 1054 1346 1390.0 L5G:1 Type1 Inactive DFGin 5.857 14.446 BLBplus -125.89, -155.49 52.59, 49.22 -144.94, 159.78 75.4, 92.72 64.26, -128.55 out-out out 13.432 Saltbr-out 11.593 HRD-in -72.36, -43.48 78.1, -21.55 out-out-in SNCooi out-in ActLoopNT-out 10.652 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -99.19, 103.8 APE9-dihe-in -110.98, 147.89 APE8-dihe-in -84.36, 67.57 APE8-rot-na 31.76 APE67-dihe-in -76.93, -6.96 -54.37, -34.0 APE12-dist-na 21.24 APE11-dist-na 18.193 APE10-dist-na 17.208 APE9-dist-in 7.328 None None None XRAY 2.0 0.236 0.287 A 310 278 15 0 0 1 [[1078, 1339]] 1.0 3cd8 Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4GG5A P08581 1064 1344 1390.0 0J3:1401 Type1 Inactive DFGin 5.304 14.408 BLBplus -122.37, -151.55 47.45, 47.99 -143.92, 162.16 78.19, 94.77 62.52, -137.98 out-none out 16.212 Saltbr-none 999.0 HRD-in -76.51, -53.12 85.46, -11.68 none-out-in SNCnoi out-in ActLoopNT-out 10.988 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -99.59, 119.56 APE9-dihe-in -118.12, 113.35 APE8-dihe-in -87.92, 83.02 APE8-rot-na 29.52 APE67-dihe-in -78.46, -1.6 -57.29, -40.61 APE12-dist-na 18.282 APE11-dist-na 17.352 APE10-dist-na 14.902 APE9-dist-in 6.873 None None None XRAY 2.423 0.216 0.268 A 319 274 7 0 0 0 [[1078, 1339]] 1.0 4gg5 Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4GG7A P08581 1064 1344 1390.0 0J8:1401 Type1 Inactive DFGin 5.931 14.439 BLBplus -116.6, -141.82 44.91, 50.77 -152.19, 157.95 88.15, 108.92 60.67, -133.34 out-out out 12.027 Saltbr-out 11.294 HRD-in -73.9, -51.35 85.25, -19.01 out-out-in SNCooi out-in ActLoopNT-out 10.967 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.93, 129.1 APE9-dihe-in -123.7, 103.59 APE8-dihe-in -79.6, 83.79 APE8-rot-na 27.48 APE67-dihe-in -83.37, -1.72 -58.24, -36.49 APE12-dist-na 17.613 APE11-dist-na 16.887 APE10-dist-na 14.707 APE9-dist-in 6.687 None None None XRAY 2.27 0.21 0.262 A 319 278 3 0 0 0 [[1078, 1339]] 1.0 4gg7 Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5EOBA P08581 1055 1345 1390.0 5QQ:1401 Type1 Inactive DFGin 6.037 14.739 BLBplus -127.28, -156.67 54.26, 46.24 -141.57, 167.58 71.68, 96.08 59.68, -131.59 out-out out 13.147 Saltbr-out 10.681 HRD-in -72.39, -47.54 73.47, -8.21 out-out-in SNCooi out-in ActLoopNT-out 11.052 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.39, 113.86 APE9-dihe-in -113.77, 125.77 APE8-dihe-in -82.16, 70.22 APE8-rot-na 29.09 APE67-dihe-in -79.07, -3.29 -48.43, -42.18 APE12-dist-na 18.831 APE11-dist-na 18.315 APE10-dist-na 15.59 APE9-dist-in 7.105 None None None XRAY 1.75 0.174 0.197 A 319 288 3 0 0 3 [[1078, 1339]] 1.0 5eob Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5YA5A P08581 1057 1345 1390.0 6TD:1401 Type1 Inactive DFGin 6.047 14.095 BLBplus -131.7, -152.67 53.68, 50.33 -145.36, 163.95 68.46, 89.67 59.78, -131.1 out-none out 16.799 Saltbr-none 999.0 HRD-in -73.73, -48.03 76.19, -12.62 none-out-in SNCnoi out-in ActLoopNT-out 10.896 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.63, 112.14 APE9-dihe-in -120.64, 147.93 APE8-dihe-in -80.59, 71.84 APE8-rot-na 30.4 APE67-dihe-in -73.5, -10.58 -60.93, -29.23 APE12-dist-na 21.585 APE11-dist-na 18.902 APE10-dist-na 17.958 APE9-dist-in 7.29 None None None XRAY 1.89 0.212 0.235 A 319 273 16 0 0 0 [[1078, 1339]] 1.0 5ya5 Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5UABA P08581 1029 1360 1390.0 84M:61401 Type1 Inactive DFGin 6.033 14.28 BLBplus -126.91, -157.0 56.09, 49.1 -144.75, 156.68 72.2, 89.62 65.5, -132.32 out-out out 12.591 Saltbr-out 11.84 HRD-in -69.3, -50.7 81.14, -11.15 out-out-in SNCooi out-in ActLoopNT-out 10.968 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.99, 109.58 APE9-dihe-in -123.38, 147.05 APE8-dihe-in -81.48, 72.06 APE8-rot-na 35.51 APE67-dihe-in -66.4, -17.83 -59.45, -34.1 APE12-dist-na 22.004 APE11-dist-na 18.578 APE10-dist-na 17.571 APE9-dist-in 7.208 None None None XRAY 1.9 0.197 0.229 A 343 288 20 0 0 0 [[1078, 1339]] 1.0 5uab Homo sapiens TYR_MET_HUMAN TYR 9.9e-92 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5UADA P08581 1029 1360 1390.0 84P:61401 Type1 Inactive DFGin 6.177 14.121 BLBplus -131.41, -161.35 58.04, 50.15 -144.41, 164.69 67.9, 85.89 61.62, -131.14 out-out out 12.498 Saltbr-out 10.204 HRD-in -69.0, -48.97 78.41, -8.03 out-out-in SNCooi out-in ActLoopNT-out 10.753 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -90.7, 117.76 APE9-dihe-in -129.09, 145.31 APE8-dihe-in -79.01, 73.18 APE8-rot-na 34.82 APE67-dihe-in -68.75, -14.7 -59.66, -32.74 APE12-dist-na 21.462 APE11-dist-na 18.144 APE10-dist-na 17.387 APE9-dist-in 7.154 None None None XRAY 2.25 0.199 0.252 A 343 291 17 0 0 0 [[1078, 1339]] 1.0 5uad Homo sapiens TYR_MET_HUMAN TYR 9.9e-92 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 6UBWA P08581 1029 1360 1390.0 84S:61401 Type1 Inactive DFGin 6.156 14.263 BLBplus -131.45, -155.48 54.45, 46.78 -140.26, 163.47 65.89, 85.19 61.55, -131.58 out-out out 12.453 Saltbr-out 11.904 HRD-in -70.83, -47.93 78.68, -11.6 out-out-in SNCooi out-in ActLoopNT-out 11.011 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.43, 111.85 APE9-dihe-in -126.25, 145.85 APE8-dihe-in -81.12, 73.68 APE8-rot-na 35.07 APE67-dihe-in -69.72, -14.3 -61.38, -31.38 APE12-dist-na 21.877 APE11-dist-na 18.515 APE10-dist-na 17.452 APE9-dist-in 7.269 None None None XRAY 2.0 0.189 0.225 A 343 296 12 0 0 0 [[1078, 1339]] 1.0 6ubw Homo sapiens TYR_MET_HUMAN TYR 9.9e-92 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3DKGA P08581 1050 1356 1390.0 SX8:1 Type1 Inactive DFGin 6.274 14.559 BLBplus -129.33, -157.14 51.1, 49.15 -145.69, 164.85 74.13, 94.49 54.79, -132.37 out-none out 13.057 Saltbr-none 999.0 HRD-in -67.95, -47.6 75.72, -15.58 none-out-none SNCnon out-none ActLoopNT-out 11.272 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 132.25 APE8-dihe-in -83.72, 63.85 APE8-rot-na 32.57 APE67-dihe-in -77.41, -6.89 -59.3, -29.42 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.562 Y1194F,Y1230L,Y1234F,Y1235D None None XRAY 1.91 0.195 0.238 A 317 281 26 0 0 17 [[1078, 1339]] 1.0 3dkg Homo sapiens TYR_MET_HUMAN TYR 2.9e-89 305.2 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 1R0PA P08581 1050 1360 1390.0 KSA:0 Type1 Inactive DFGin 6.476 14.34 BLBplus -128.87, -159.66 55.78, 40.33 -140.55, 160.82 73.45, 94.62 57.22, -140.62 out-out out 12.845 Saltbr-out 8.509 HRD-in -72.32, -48.0 70.71, -31.47 out-out-out SNCooo out-out ActLoopNT-out 11.433 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -136.19, 45.76 APE9-dihe-in -67.34, 140.95 APE8-dihe-in -80.24, 67.34 APE8-rot-na 34.02 APE67-dihe-in -69.09, -8.34 -56.1, -27.84 APE12-dist-na 19.241 APE11-dist-na 22.747 APE10-dist-na 20.477 APE9-dist-out 9.135 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 1.8 0.171 0.197 A 312 301 10 0 0 0 [[1078, 1339]] 1.0 1r0p Homo sapiens TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5HNIX P08581 1063 1356 1390.0 63B:1401 Type1 Inactive DFGin 6.582 14.461 BLBplus -128.77, -162.75 58.27, 52.75 -152.11, 164.27 72.11, 107.85 73.64, -141.36 out-out out 12.388 Saltbr-out 10.807 HRD-in -73.69, -52.32 85.1, -22.83 out-out-none SNCoon out-none ActLoopNT-out 11.095 ActLoopCT-none TYR APEdihe_nnnan APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-na 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.71 0.227 0.245 X 312 245 47 0 0 18 [[1078, 1339]] 1.0 5hni Homo sapiens TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5HNIY P08581 1063 1356 1390.0 63B:1401 Type1 Inactive DFGin 6.744 14.676 BLBplus -128.6, -162.9 56.36, 57.68 -160.11, 163.59 72.74, 105.71 74.96, -141.42 out-out out 15.004 Saltbr-out 12.553 HRD-in -70.57, -55.83 88.3, -19.62 out-out-none SNCoon out-none ActLoopNT-out 10.921 ActLoopCT-none TYR APEdihe_nnnan APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-na 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.71 0.227 0.245 Y 312 245 47 0 0 18 [[1078, 1339]] 1.0 5hni Homo sapiens TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5HO6A P08581 1063 1356 1390.0 63K:1401 Type1 Inactive DFGin 6.392 15.144 BLBplus -140.59, -157.22 42.62, 56.18 -144.55, 164.36 76.38, 97.31 74.25, -133.43 out-out out 13.138 Saltbr-out 11.309 HRD-in -69.03, -58.48 93.08, -20.11 out-out-none SNCoon out-none ActLoopNT-out 11.35 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.63 APE8-dihe-in -80.42, 70.67 APE8-rot-na 33.19 APE67-dihe-in -74.88, -4.04 -52.25, -37.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.252 Y1194F,Y1234F,Y1235D None None XRAY 1.97 999.0 999.0 A 312 240 52 0 0 17 [[1078, 1339]] 1.0 5ho6 Homo sapiens TYR_MET_HUMAN TYR 8.2e-90 306.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3QTIA P08581 1052 1360 1390.0 3QT:1 Type1 Inactive DFGin 5.986 14.247 BLBplus -128.5, -152.13 51.75, 55.68 -149.19, 167.26 67.71, 86.54 61.1, -130.78 out-out out 12.791 Saltbr-out 11.363 HRD-in -64.94, -54.68 75.74, -14.73 out-out-out SNCooo out-out ActLoopNT-out 11.085 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -50.26 APE8-dihe-in -81.01, 60.83 APE8-rot-na 28.97 APE67-dihe-in -68.29, -9.03 -49.07, -40.5 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.036 Y1194F,Y1234F,Y1235D None None XRAY 2.0 0.184 0.213 A 314 292 17 0 0 10 [[1078, 1339]] 1.0 3qti Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3QTIB P08581 1058 1360 1390.0 3QT:1 Type1 Inactive DFGin 6.046 14.105 BLBplus -128.94, -152.28 51.92, 56.0 -149.61, 167.07 67.92, 86.59 61.23, -130.04 out-out out 12.391 Saltbr-out 11.833 HRD-in -63.79, -55.32 80.3, -19.96 out-out-out SNCooo out-out ActLoopNT-out 11.086 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -49.95 APE8-dihe-in -81.99, 60.89 APE8-rot-na 28.35 APE67-dihe-in -67.92, -9.06 -48.59, -41.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.071 Y1194F,Y1234F,Y1235D None None XRAY 2.0 0.184 0.213 B 314 280 23 0 0 10 [[1078, 1339]] 1.0 3qti Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3DKFA P08581 1050 1360 1390.0 SX8:60001 Type1 Inactive DFGin 6.26 14.463 BLBplus -127.05, -153.9 49.97, 55.44 -149.93, 164.21 68.29, 85.91 54.3, -128.07 out-none out 13.145 Saltbr-none 999.0 HRD-in -72.55, -46.99 75.69, -17.26 none-out-none SNCnon out-none ActLoopNT-out 10.989 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 80.53 APE9-dihe-in -59.08, 148.93 APE8-dihe-in -81.61, 66.86 APE8-rot-na 29.34 APE67-dihe-in -76.88, -10.9 -58.27, -31.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 19.815 APE9-dist-in 7.622 Y1194F,Y1234F,Y1235D None None XRAY 1.8 0.191 0.233 A 317 293 18 0 0 13 [[1078, 1339]] 1.0 3dkf Homo sapiens TYR_MET_HUMAN TYR 8.6e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3A4PA P08581 1063 1360 1390.0 DFQ:1362 Type1 Inactive DFGin 6.091 14.332 BLBplus -133.73, -165.54 69.08, 42.15 -140.6, 163.85 58.15, 78.63 70.77, -133.85 out-out out 12.692 Saltbr-out 11.091 HRD-in -67.67, -48.03 79.13, -18.18 out-out-out SNCooo out-out ActLoopNT-out 10.928 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -62.82, -16.13 APE9-dihe-in -103.62, 128.61 APE8-dihe-in -81.13, 79.24 APE8-rot-na 39.51 APE67-dihe-in -70.65, -14.82 -64.45, -30.75 APE12-dist-na 999.0 APE11-dist-na 21.71 APE10-dist-na 17.268 APE9-dist-in 7.686 Y1194F,Y1234F,Y1235D None None XRAY 2.54 0.186 0.24 A 319 285 13 0 0 10 [[1078, 1339]] 1.0 3a4p Homo sapiens TYR_MET_HUMAN TYR 8.8e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5HOAA P08581 1065 1356 1390.0 63K:1401 Type1 Inactive DFGin 6.68 14.954 BLBplus -129.02, -150.36 47.05, 45.12 -132.57, 158.73 62.16, 148.21 76.83, -120.13 out-out out 13.199 Saltbr-out 12.094 HRD-in -69.17, -54.51 81.48, -21.01 out-out-none SNCoon out-none ActLoopNT-out 10.789 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 126.64 APE8-dihe-in -83.0, 61.69 APE8-rot-na 26.13 APE67-dihe-in -70.08, -8.02 -54.44, -40.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.217 None None None XRAY 2.14 999.0 999.0 A 312 225 62 0 0 17 [[1078, 1339]] 1.0 5hoa Homo sapiens TYR_MET_HUMAN TYR 4.6e-89 304.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5HORA P08581 1064 1356 1390.0 63K:1401 Type1 Inactive DFGin 5.805 14.002 BLBplus -124.94, -148.7 45.83, 47.65 -141.57, 163.86 75.07, 87.77 65.83, -137.92 out-out out 11.674 Saltbr-out 13.939 HRD-in -69.94, -55.46 81.49, -11.98 out-out-out SNCooo out-out ActLoopNT-out 11.137 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 72.57 APE8-dihe-in -91.32, 77.45 APE8-rot-na 31.4 APE67-dihe-in -70.12, -10.2 -48.97, -48.33 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.163 Y1194F,Y1234F,Y1235D,M1250T None None XRAY 2.2 999.0 999.0 A 312 247 44 0 0 15 [[1078, 1339]] 1.0 5hor Homo sapiens TYR_MET_HUMAN TYR 2.5e-89 305.2 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3U6HA P08581 1051 1351 1390.0 03X:1 Type1.5_Front Inactive DFGin 5.5 14.419 BLBplus -145.15, 179.51 61.38, 23.56 -82.38, 149.62 53.62, 89.86 90.75, 999.0 out-out out 12.113 Saltbr-out 7.679 HRD-in -72.28, -53.74 82.85, -16.84 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 50.02 APE8-rot-na 30.69 APE67-dihe-in -72.37, 0.17 -64.56, -34.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.0 0.221 0.274 A 309 280 21 0 0 21 [[1078, 1339]] 1.0 3u6h Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3U6IA P08581 1051 1351 1390.0 044:1 Type1.5_Front Inactive DFGin 5.277 14.587 BLBplus -134.83, 174.49 60.14, 23.77 -73.51, 140.85 47.46, 91.22 78.44, 999.0 out-out out 12.048 Saltbr-out 8.482 HRD-in -67.0, -53.9 81.23, -23.55 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 129.68 APE8-dihe-in -90.4, 68.47 APE8-rot-na 28.01 APE67-dihe-in -76.04, -5.5 -62.36, -28.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.691 None None None XRAY 2.1 0.208 0.257 A 309 281 20 0 0 20 [[1078, 1339]] 1.0 3u6i Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5HLWA P08581 1057 1355 1390.0 62E:1402 Type1 Inactive DFGin 4.513 15.239 BLBtrans -116.03, -153.14 53.76, 45.98 -117.52, 136.96 172.48, 77.03 55.42, -120.5 out-out out 12.132 Saltbr-out 12.527 HRD-in -66.33, -51.4 79.89, -18.18 out-out-in SNCooi out-in ActLoopNT-out 10.958 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.84, 121.53 APE9-dihe-in -119.58, 91.77 APE8-dihe-in -84.22, 69.13 APE8-rot-na 24.1 APE67-dihe-in -74.27, 0.43 -39.16, -50.96 APE12-dist-na 999.0 APE11-dist-na 16.106 APE10-dist-na 13.673 APE9-dist-in 6.72 Y1230H None None XRAY 1.97 999.0 999.0 A 299 284 14 0 0 5 [[1078, 1339]] 1.0 5hlw Homo sapiens TYR_MET_HUMAN TYR 1.4e-91 312.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3EFKA P08581 1054 1351 1390.0 MT4:1 Type1.5_Front Inactive DFGin 5.064 14.093 None -134.75, -178.01 61.2, 27.83 -81.51, 999.0 42.72, 82.19 999.0, 999.0 out-out out 12.813 Saltbr-out 7.941 HRD-in -70.71, -51.36 83.62, -19.92 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 26.89 APE8-rot-na 29.1 APE67-dihe-in -75.12, -5.25 -59.44, -32.91 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.2 0.257 0.292 A 310 276 22 0 0 22 [[1078, 1339]] 1.0 3efk Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3EFKB P08581 1054 1351 1390.0 MT4:2 Type1.5_Front Inactive DFGin 5.171 14.171 None -136.11, -178.89 60.83, 31.64 -88.75, 999.0 42.99, 77.64 999.0, 999.0 out-out out 12.549 Saltbr-out 7.623 HRD-in -66.0, -59.6 86.12, -12.02 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 28.71 APE8-rot-na 33.98 APE67-dihe-in -75.58, -3.26 -55.05, -32.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.2 0.257 0.292 B 310 272 26 0 0 22 [[1078, 1339]] 1.0 3efk Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3RHKB P08581 1046 1344 1390.0 M97:1 Type1 Inactive DFGout 16.956 9.456 BBAminus -103.9, 147.08 -123.26, 84.4 -80.96, -74.13 286.43, 109.84 68.17, -76.36 out-none out 18.292 Saltbr-none 999.0 HRD-in -76.8, -46.7 79.69, -10.43 none-out-in SNCnoi out-in ActLoopNT-out 15.535 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.43, 129.46 APE9-dihe-in -122.69, 110.91 APE8-dihe-in -78.44, 71.02 APE8-rot-na 31.3 APE67-dihe-in -74.35, -3.39 -48.6, -48.25 APE12-dist-na 12.656 APE11-dist-na 12.57 APE10-dist-na 10.001 APE9-dist-in 6.793 None None None XRAY 1.94 0.203 0.254 B 318 299 0 0 0 0 [[1078, 1339]] 1.0 3rhk Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8ANSA P08581 1052 1346 1390.0 MDI:1402 Type1.5_Front Inactive DFGout 21.988 12.134 BBAminus -113.69, 156.55 -126.28, 136.74 -116.06, 28.6 291.38, 93.7 114.66, -11.19 out-none out 16.715 Saltbr-none 999.0 HRD-in -66.61, -50.14 72.94, -14.68 none-in-none SNCnin in-none ActLoopNT-in 2.814 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 145.39 APE8-dihe-in -71.16, 118.3 APE8-rot-na 25.27 APE67-dihe-in -73.48, 1.82 -58.2, -31.36 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.972 D1228V None None XRAY 2.01 0.232 0.277 A 296 277 18 0 0 15 [[1078, 1339]] 1.0 8ans Homo sapiens TYR_MET_HUMAN TYR 1.3e-91 312.5 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8VI1A P08581 1053 1346 1390.0 A1AB1:1401 Type1.5_Front Inactive DFGout 14.819 9.436 BBAminus -108.11, 147.26 -117.32, 132.26 -96.14, -16.7 282.99, 100.28 74.09, 31.57 out-out out 14.533 Saltbr-out 11.844 HRD-in -73.59, -41.12 80.85, -53.9 out-out-out SNCooo out-out ActLoopNT-out 8.453 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -73.38, 142.57 APE9-dihe-in -84.31, 136.88 APE8-dihe-in -79.64, 70.29 APE8-rot-na 34.05 APE67-dihe-in -83.39, -14.09 -70.01, -29.83 APE12-dist-na 999.0 APE11-dist-na 9.426 APE10-dist-na 10.403 APE9-dist-out 8.627 None None None XRAY 3.11 0.253 0.298 A 309 284 10 0 0 7 [[1078, 1339]] 1.0 8vi1 Homo sapiens TYR_MET_HUMAN TYR 1.1e-91 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8VI1B P08581 1050 1345 1390.0 A1AB1:1401 Type1.5_Front Inactive DFGout 15.272 8.725 BBAminus -108.54, 151.43 -123.32, 136.74 -110.22, 12.52 275.64, 111.62 71.37, 50.45 out-out out 15.162 Saltbr-out 11.973 HRD-in -74.07, -53.17 75.69, 9.37 out-out-in SNCooi out-in ActLoopNT-out 7.68 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.88, 110.5 APE9-dihe-in -114.0, 153.27 APE8-dihe-in -80.31, 90.69 APE8-rot-na 32.48 APE67-dihe-in -77.51, -25.6 -72.23, -29.3 APE12-dist-na 999.0 APE11-dist-na 9.908 APE10-dist-na 10.171 APE9-dist-in 7.148 None None None XRAY 3.11 0.253 0.298 B 309 287 9 0 0 9 [[1078, 1339]] 1.0 8vi1 Homo sapiens TYR_MET_HUMAN TYR 1.1e-91 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8AN8A P08581 1073 1345 1390.0 MDI:1405 Type1.5_Front Inactive DFGout 21.707 13.171 BBAminus -94.14, 151.51 -120.93, 127.96 -109.22, 32.25 303.58, 88.2 110.31, 1.2 out-out out 16.43 Saltbr-out 20.272 HRD-in -54.67, -51.39 71.04, -1.89 out-in-none SNCoin in-none ActLoopNT-in 2.9 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 58.15 APE8-rot-na 3.41 APE67-dihe-in -68.88, -23.67 -46.98, -37.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.394 0.244 0.298 A 296 244 29 0 0 10 [[1078, 1339]] 1.0 8an8 Homo sapiens TYR_MET_HUMAN TYR 5.9e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8AN8B P08581 1058 1345 1390.0 MDI:1402 Type1.5_Front Inactive DFGout 21.849 13.195 BBAminus -106.1, 150.5 -120.05, 128.27 -113.48, 46.76 300.29, 99.64 94.11, -3.01 out-out out 16.643 Saltbr-out 17.83 HRD-in -61.73, -46.11 67.66, -9.48 out-in-none SNCoin in-none ActLoopNT-in 2.97 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 100.6 APE8-dihe-in -76.12, 118.46 APE8-rot-na 29.89 APE67-dihe-in -71.35, -4.52 -60.81, -23.43 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.046 None None None XRAY 2.394 0.244 0.298 B 296 263 25 0 0 9 [[1078, 1339]] 1.0 8an8 Homo sapiens TYR_MET_HUMAN TYR 5.9e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 6SDCA P08581 1052 1346 1390.0 88Z:1401 Type2 Inactive DFGout 14.755 9.992 BBAminus -145.61, -169.98 -156.56, 116.19 -59.96, -26.46 279.97, 77.13 50.32, -121.48 in-in in 8.796 Saltbr-in 2.861 HRD-in -66.32, -54.96 80.1, -13.51 in-out-in SNCioi out-in ActLoopNT-out 16.386 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -83.94, 108.39 APE9-dihe-in -108.81, 143.16 APE8-dihe-in -83.72, 68.12 APE8-rot-na 31.17 APE67-dihe-in -78.0, -5.37 -48.86, -37.15 APE12-dist-na 999.0 APE11-dist-na 13.258 APE10-dist-na 11.102 APE9-dist-in 7.166 D1228V None None XRAY 1.67 0.203 0.242 A 309 286 9 0 0 5 [[1078, 1339]] 1.0 6sdc Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 6SDDA P08581 1062 1344 1390.0 353:1401 Type2 Inactive DFGout 15.67 9.526 BBAminus -149.49, -170.93 -153.94, 114.14 -65.06, -13.55 275.17, 88.26 76.54, -107.92 out-out out 12.411 Saltbr-out 7.347 HRD-in -67.87, -54.54 79.9, -17.29 out-out-in SNCooi out-in ActLoopNT-out 17.253 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.26, 119.13 APE9-dihe-in -121.4, 98.95 APE8-dihe-in -84.87, 81.64 APE8-rot-na 25.83 APE67-dihe-in -76.62, 2.13 -39.71, -53.85 APE12-dist-na 11.436 APE11-dist-na 11.546 APE10-dist-na 6.815 APE9-dist-in 6.618 D1228V None None XRAY 1.93 0.211 0.23 A 309 271 12 0 0 0 [[1078, 1339]] 1.0 6sdd Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 9C1RA P08581 1048 1348 1390.0 A1ATS:61402 Type2 Inactive DFGout 14.996 12.36 BBAminus -147.48, -173.02 -151.09, 114.21 -68.49, -19.37 279.38, 51.8 69.45, 999.0 in-out in 8.466 Saltbr-out 4.388 HRD-in -73.44, -51.96 79.97, -12.22 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 71.42 APE8-rot-na 34.84 APE67-dihe-in -69.08, -15.96 -61.0, -31.76 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 D1228N None None XRAY 1.59 0.17 0.195 A 307 280 21 0 0 21 [[1078, 1339]] 1.0 9c1r Homo sapiens TYR_MET_HUMAN TYR 1e-91 313.3 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3LQ8A P08581 1053 1345 1390.0 88Z:1 Type2 Inactive DFGout 14.861 9.989 BBAminus -150.09, -172.74 -147.86, 117.02 -56.28, -26.81 274.5, 87.89 59.54, -126.97 in-in in 8.647 Saltbr-in 2.7 HRD-in -70.16, -54.71 79.85, -12.74 in-out-in SNCioi out-in ActLoopNT-out 16.446 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.38, 117.69 APE9-dihe-in -124.2, 124.76 APE8-dihe-in -78.42, 71.53 APE8-rot-na 27.34 APE67-dihe-in -76.25, -4.88 -56.16, -37.64 APE12-dist-na 999.0 APE11-dist-na 14.007 APE10-dist-na 9.891 APE9-dist-in 7.129 None None None XRAY 2.02 0.194 0.252 A 302 278 15 0 0 8 [[1078, 1339]] 1.0 3lq8 Homo sapiens TYR_MET_HUMAN TYR 6.4e-92 313.6 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 6SD9A P08581 1062 1345 1390.0 88Z:1402 Type2 Inactive DFGout 14.875 10.089 BBAminus -142.16, -169.29 -149.74, 121.34 -65.96, -2.71 275.09, 79.25 44.01, -118.14 in-in in 8.835 Saltbr-in 3.063 HRD-in -63.65, -57.37 87.84, -32.21 in-out-in SNCioi out-in ActLoopNT-out 15.81 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -103.67, 97.49 APE9-dihe-in -110.0, 137.15 APE8-dihe-in -89.8, 72.46 APE8-rot-na 28.25 APE67-dihe-in -72.7, -14.18 -53.41, -37.28 APE12-dist-na 14.557 APE11-dist-na 14.701 APE10-dist-na 9.852 APE9-dist-in 7.607 None None None XRAY 2.35 0.212 0.27 A 309 265 19 0 0 9 [[1078, 1339]] 1.0 6sd9 Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4EEVA P08581 1045 1346 1390.0 L1X:1401 Type2 Inactive DFGout 14.835 11.811 BBAminus -150.99, -173.15 -148.09, 112.51 -69.31, -18.69 280.19, 68.72 62.91, 999.0 in-out in 9.438 Saltbr-out 4.019 HRD-in -69.54, -52.28 78.43, -16.27 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -34.59 APE9-dihe-in -112.24, 136.57 APE8-dihe-in -76.84, 69.93 APE8-rot-na 35.57 APE67-dihe-in -75.09, -8.21 -54.81, -37.27 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.399 None None None XRAY 1.8 0.19 0.215 A 317 283 19 0 0 19 [[1078, 1339]] 1.0 4eev Homo sapiens TYR_MET_HUMAN TYR 7.6e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 4MXCA P08581 1052 1346 1390.0 DWF:1401 Type2 Inactive DFGout 14.41 10.337 BBAminus -151.35, -174.18 -156.99, 122.43 -67.95, -16.78 287.52, 70.23 58.23, -116.98 in-in in 8.929 Saltbr-in 3.515 HRD-in -73.25, -51.06 80.68, -17.87 in-out-in SNCioi out-in ActLoopNT-out 15.287 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.68, 108.68 APE9-dihe-in -118.71, 133.81 APE8-dihe-in -79.71, 72.93 APE8-rot-na 28.81 APE67-dihe-in -75.71, -5.79 -60.94, -31.89 APE12-dist-na 999.0 APE11-dist-na 13.628 APE10-dist-na 10.273 APE9-dist-in 7.344 None None None XRAY 1.632 0.18 0.207 A 319 290 5 0 0 5 [[1078, 1339]] 1.0 4mxc Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5HTIA P08581 1052 1346 1390.0 66L:1401 Type2 Inactive DFGout 14.763 10.152 BBAminus -150.22, -171.22 -155.42, 114.97 -62.9, -20.19 274.11, 85.9 55.43, -118.13 in-in in 8.699 Saltbr-in 2.823 HRD-in -77.45, -49.55 78.7, -14.93 in-out-in SNCioi out-in ActLoopNT-out 15.499 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.35, 116.23 APE9-dihe-in -109.51, 139.44 APE8-dihe-in -78.22, 74.02 APE8-rot-na 29.94 APE67-dihe-in -80.7, -2.62 -63.3, -30.0 APE12-dist-na 999.0 APE11-dist-na 12.385 APE10-dist-na 10.932 APE9-dist-in 7.21 None None None XRAY 1.66 0.182 0.206 A 319 290 5 0 0 5 [[1078, 1339]] 1.0 5hti Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7V3SA P08581 1053 1346 1390.0 5I9:61401 Type2 Inactive DFGout 14.757 10.258 BBAminus -149.82, -171.75 -156.83, 112.28 -60.3, -21.2 277.0, 84.81 61.69, -129.71 in-in in 8.631 Saltbr-in 2.978 HRD-in -72.86, -54.04 83.09, -13.67 in-out-in SNCioi out-in ActLoopNT-out 15.578 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.7, 113.54 APE9-dihe-in -114.51, 140.19 APE8-dihe-in -79.44, 72.02 APE8-rot-na 33.09 APE67-dihe-in -77.15, -5.33 -64.06, -28.7 APE12-dist-na 999.0 APE11-dist-na 13.959 APE10-dist-na 10.578 APE9-dist-in 7.339 None None None XRAY 1.9 0.166 0.195 A 319 284 10 0 0 10 [[1078, 1339]] 1.0 7v3s Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3VW8A P08581 1024 1352 1390.0 DF6:61401 Type2 Inactive DFGout 14.985 9.691 BBAminus -161.12, -169.12 -159.8, 118.44 -64.07, -25.07 277.76, 84.74 53.88, -122.36 in-in in 8.069 Saltbr-in 2.768 HRD-in -68.84, -53.41 80.47, -15.73 in-out-in SNCioi out-in ActLoopNT-out 16.135 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.55, 104.4 APE9-dihe-in -121.2, 146.4 APE8-dihe-in -81.53, 72.39 APE8-rot-na 32.73 APE67-dihe-in -70.52, -13.63 -60.67, -36.33 APE12-dist-na 999.0 APE11-dist-na 13.724 APE10-dist-na 10.723 APE9-dist-in 7.187 None None None XRAY 2.1 0.215 0.259 A 328 303 11 0 0 6 [[1078, 1339]] 1.0 3vw8 Homo sapiens TYR_MET_HUMAN TYR 8.5e-92 313.4 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3CE3A P08581 1054 1360 1390.0 1FN:1401 Type2 Inactive DFGout 15.829 11.096 BBAminus -152.23, -166.63 -149.31, 110.67 -63.52, 88.97 263.94, 98.6 -40.81, 999.0 out-out out 10.457 Saltbr-out 7.572 HRD-in -64.74, -51.71 83.06, -16.24 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 154.52, -34.98 APE9-dihe-in -91.22, 168.57 APE8-dihe-in -87.87, 55.4 APE8-rot-na 29.31 APE67-dihe-in -83.51, -5.01 -45.55, -24.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.489 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 2.4 0.209 0.275 A 314 293 14 0 0 14 [[1078, 1339]] 1.0 3ce3 Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3CTHA P08581 1052 1360 1390.0 319:2001 Type2 Inactive DFGout 15.098 10.005 BBAminus -148.1, -166.94 -151.56, 109.98 -65.26, 53.17 258.77, 111.11 -176.8, 999.0 out-out out 10.323 Saltbr-out 4.075 HRD-in -66.61, -58.23 83.78, -12.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -74.2, -8.67 APE9-dihe-in -55.09, 119.34 APE8-dihe-in -75.87, 63.89 APE8-rot-na 35.54 APE67-dihe-in -72.56, -7.97 -55.16, -26.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.642 Y1194F,Y1234F,Y1235D None None XRAY 2.3 0.212 0.273 A 314 295 14 0 0 14 [[1078, 1339]] 1.0 3cth Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3F82A P08581 1055 1360 1390.0 353:2001 Type2 Inactive DFGout 15.478 9.639 BBAminus -148.75, -169.98 -153.95, 103.18 -56.5, -43.04 270.25, 97.71 47.11, 999.0 out-out out 10.115 Saltbr-out 5.31 HRD-in -72.25, -53.17 82.39, -19.33 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 37.94 APE9-dihe-in -74.59, 146.36 APE8-dihe-in -82.33, 66.47 APE8-rot-na 33.58 APE67-dihe-in -70.27, -11.92 -52.54, -32.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.373 Y1194F,Y1234F,Y1235D None None XRAY 2.5 0.183 0.253 A 314 278 28 0 0 19 [[1078, 1339]] 1.0 3f82 Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3L8VA P08581 1054 1360 1390.0 L8V:1 Type2 Inactive DFGout 15.382 9.641 BBAminus -142.33, -172.03 -148.67, 112.08 -62.2, -49.07 262.9, 96.95 155.4, 999.0 in-out in 9.132 Saltbr-out 4.512 HRD-in -64.23, -54.91 82.78, -23.22 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -164.33, -4.28 APE9-dihe-in -77.45, 145.0 APE8-dihe-in -83.45, 66.14 APE8-rot-na 33.01 APE67-dihe-in -69.99, -14.31 -48.56, -35.56 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.505 Y1194F,Y1234F,Y1235D None None XRAY 2.4 0.185 0.237 A 314 293 14 0 0 14 [[1078, 1339]] 1.0 3l8v Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OUUA P08581 1059 1346 1390.0 W49:1404 Type3 Inactive DFGout 13.515 6.876 BBAminus -147.46, -168.73 -151.04, 108.81 -112.08, 40.61 288.5, 94.51 -110.14, -161.37 out-out out 12.355 Saltbr-out 10.46 HRD-in -63.12, -55.99 76.4, -17.82 out-out-in SNCooi out-in ActLoopNT-out 9.091 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.11, 150.07 APE9-dihe-in -72.2, 149.25 APE8-dihe-in -80.89, 58.5 APE8-rot-na 27.43 APE67-dihe-in -74.53, -1.63 -44.12, -49.33 APE12-dist-na 999.0 APE11-dist-na 6.546 APE10-dist-na 10.792 APE9-dist-in 7.893 D1228V None None XRAY 1.77 0.203 0.225 A 309 284 4 0 0 4 [[1078, 1339]] 1.0 8ouu Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OUUB P08581 1057 1346 1390.0 W49:1405 Type3 Inactive DFGout 13.488 6.97 BBAminus -144.89, -171.19 -149.83, 102.26 -101.8, 30.99 273.18, 101.18 -108.36, -152.3 out-out out 12.311 Saltbr-out 10.383 HRD-in -62.48, -51.05 73.17, -16.23 out-out-out SNCooo out-out ActLoopNT-out 9.188 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -63.11, 139.96 APE9-dihe-in -71.28, 138.06 APE8-dihe-in -78.82, 59.01 APE8-rot-na 36.37 APE67-dihe-in -74.44, -3.9 -45.73, -43.18 APE12-dist-na 10.634 APE11-dist-na 6.56 APE10-dist-na 11.61 APE9-dist-out 8.235 D1228V None None XRAY 1.77 0.203 0.225 B 309 290 0 0 0 0 [[1078, 1339]] 1.0 8ouu Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OUVA P08581 1053 1346 1390.0 W3R:1401 Type3 Inactive DFGout 13.432 6.982 BBAminus -150.55, -166.67 -153.94, 107.37 -108.14, 42.08 281.33, 84.2 -114.79, -152.59 out-out out 12.492 Saltbr-out 10.788 HRD-in -65.45, -52.15 77.68, -39.15 out-out-out SNCooo out-out ActLoopNT-out 9.594 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -77.07, 137.88 APE9-dihe-in -75.04, 140.45 APE8-dihe-in -83.02, 58.2 APE8-rot-na 29.39 APE67-dihe-in -74.39, -2.19 -46.6, -48.03 APE12-dist-na 10.641 APE11-dist-na 6.116 APE10-dist-na 10.331 APE9-dist-out 8.21 D1228V None None XRAY 1.783 0.193 0.22 A 309 294 0 0 0 0 [[1078, 1339]] 1.0 8ouv Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OUVB P08581 1057 1346 1390.0 W3R:1403 Type3 Inactive DFGout 13.51 7.147 BBAminus -147.83, -171.85 -148.7, 102.33 -101.0, 36.34 274.67, 80.19 -118.46, -149.43 out-out out 12.359 Saltbr-out 10.666 HRD-in -65.36, -51.5 76.95, -23.29 out-out-out SNCooo out-out ActLoopNT-out 9.126 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -67.24, 136.99 APE9-dihe-in -67.7, 139.76 APE8-dihe-in -82.33, 58.02 APE8-rot-na 32.55 APE67-dihe-in -77.97, -2.31 -52.96, -31.41 APE12-dist-na 10.989 APE11-dist-na 6.865 APE10-dist-na 11.983 APE9-dist-out 8.293 D1228V None None XRAY 1.783 0.193 0.22 B 309 290 0 0 0 0 [[1078, 1339]] 1.0 8ouv Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OV7A P08581 1051 1346 1390.0 W3W:1401 Type3 Inactive DFGout 16.903 9.364 BBAminus -153.61, -165.39 -151.4, 119.76 -84.83, -13.59 281.18, 90.67 -96.35, -144.67 out-out out 12.327 Saltbr-out 10.74 HRD-in -65.11, -52.02 80.74, -20.69 out-out-out SNCooo out-out ActLoopNT-out 6.49 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -77.6, 93.42 APE9-dihe-in -116.32, 89.67 APE8-dihe-out -52.96, -30.95 APE8-rot-na 334.19 APE67-dihe-in -78.41, -2.44 -56.72, -27.38 APE12-dist-na 16.993 APE11-dist-na 17.033 APE10-dist-na 11.812 APE9-dist-out 10.786 D1228V None None XRAY 1.95 0.274 0.287 A 309 289 7 0 0 0 [[1078, 1339]] 1.0 8ov7 Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OVZA P08581 1061 1346 1390.0 W3N:1411 Type3 Inactive DFGout 13.353 7.006 BBAminus -146.53, -171.32 -145.54, 124.96 -119.17, 42.96 279.31, 88.35 -118.39, -154.9 out-out out 12.132 Saltbr-out 11.597 HRD-in -61.66, -54.56 76.63, -30.67 out-out-out SNCooo out-out ActLoopNT-out 9.29 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -75.2, 144.98 APE9-dihe-in -69.5, 147.31 APE8-dihe-in -82.74, 56.17 APE8-rot-na 31.37 APE67-dihe-in -67.83, -2.09 -44.04, -52.84 APE12-dist-na 10.733 APE11-dist-na 6.553 APE10-dist-na 11.677 APE9-dist-out 8.152 D1228V None None XRAY 2.206 0.227 0.275 A 309 286 0 0 0 0 [[1078, 1339]] 1.0 8ovz Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OVZB P08581 1057 1346 1390.0 W3N:1410 Type3 Inactive DFGout 13.772 6.771 BBAminus -146.01, -169.05 -148.05, 116.27 -112.98, 47.33 264.21, 88.29 -128.7, -142.69 out-out out 12.232 Saltbr-out 11.019 HRD-in -68.15, -51.01 72.21, -18.47 out-out-out SNCooo out-out ActLoopNT-out 9.007 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -70.33, 137.86 APE9-dihe-in -70.76, 127.71 APE8-dihe-in -79.23, 64.44 APE8-rot-na 29.84 APE67-dihe-in -76.38, -8.07 -54.71, -26.75 APE12-dist-na 10.89 APE11-dist-na 6.759 APE10-dist-na 11.936 APE9-dist-out 8.433 D1228V None None XRAY 2.206 0.227 0.275 B 309 290 0 0 0 0 [[1078, 1339]] 1.0 8ovz Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OWGA P08581 1060 1344 1390.0 W40:1401 Type3 Inactive DFGout 15.215 7.185 BBAminus -151.69, 176.81 -129.27, 111.57 -101.99, 63.08 247.0, 19.93 135.49, 100.91 out-none out 12.564 Saltbr-none 999.0 HRD-in -54.29, -59.14 87.34, -18.08 none-out-none SNCnon out-none ActLoopNT-out 6.455 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 39.54 APE8-rot-na 32.71 APE67-dihe-in -69.3, -0.31 -58.16, -36.16 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 D1228V None None XRAY 2.631 0.283 0.329 A 309 244 41 0 0 17 [[1078, 1339]] 1.0 8owg Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OWGB P08581 1060 1343 1390.0 W40:1401 Type3 Inactive DFGout 13.474 7.027 BBAminus -143.52, -173.91 -145.15, 96.11 -104.84, 19.11 287.04, 87.7 -144.89, 36.92 out-none out 12.676 Saltbr-none 999.0 HRD-in -57.0, -54.53 71.26, 2.24 none-out-in SNCnoi out-in ActLoopNT-out 8.803 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.21, 155.54 APE9-dihe-in -138.84, 156.19 APE8-dihe-in -90.42, 73.4 APE8-rot-na 26.27 APE67-dihe-in -74.77, 0.81 -53.95, -37.48 APE12-dist-na 13.969 APE11-dist-na 10.934 APE10-dist-na 9.933 APE9-dist-in 7.283 D1228V None None XRAY 2.631 0.283 0.329 B 309 246 38 0 0 14 [[1078, 1339]] 1.0 8owg Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OWGC P08581 1060 1343 1390.0 W40:1401 Type3 Inactive DFGout 13.494 7.396 BBAminus -137.63, 176.74 -129.85, 94.81 -103.25, 51.6 272.59, 87.18 162.66, 999.0 out-none out 12.719 Saltbr-none 999.0 HRD-in -60.14, -44.34 69.98, -16.33 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.95 APE8-dihe-in -84.26, 62.47 APE8-rot-na 30.42 APE67-dihe-in -68.37, 4.72 -58.51, -48.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.132 D1228V None None XRAY 2.631 0.283 0.329 C 309 235 49 0 0 20 [[1078, 1339]] 1.0 8owg Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 8OW3A P08581 1058 1345 1390.0 W40:1401 Type3 Inactive DFGout 13.282 6.949 BBAminus -144.85, -172.89 -148.19, 116.28 -124.16, 31.55 280.56, 89.39 -106.2, 999.0 out-none out 12.663 Saltbr-none 999.0 HRD-in -58.32, -54.99 72.45, -5.24 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 130.74 APE8-dihe-in -87.02, 65.42 APE8-rot-na 27.11 APE67-dihe-in -76.81, 1.52 -53.65, -34.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.743 None None None XRAY 2.27 0.247 0.295 A 309 258 30 0 0 20 [[1078, 1339]] 1.0 8ow3 Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3RHKA P08581 1049 1346 1390.0 M97:1 Type1 Inactive DFGout 16.804 10.238 None -104.85, 145.39 -125.11, 99.2 -79.8, 96.93 312.95, 103.75 -66.36, -102.37 out-out out 17.662 Saltbr-out 17.877 HRD-in -66.53, -55.84 80.88, -14.04 out-out-in SNCooi out-in ActLoopNT-out 14.853 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.18, 132.08 APE9-dihe-in -131.35, 110.62 APE8-dihe-in -80.24, 69.86 APE8-rot-na 30.58 APE67-dihe-in -67.83, -6.07 -48.09, -47.84 APE12-dist-na 13.045 APE11-dist-na 12.499 APE10-dist-na 10.098 APE9-dist-in 7.007 None None None XRAY 1.94 0.203 0.254 A 318 298 0 0 0 0 [[1078, 1339]] 1.0 3rhk Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3EFJA P08581 1054 1351 1390.0 MT3:1 Type1.5_Front Inactive DFGout 14.778 8.785 None -121.25, 162.39 -104.89, -29.61 54.56, 999.0 265.44, 110.5 999.0, 999.0 out-out out 13.253 Saltbr-out 9.71 HRD-in -61.96, -46.17 77.81, -13.58 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 59.71 APE8-rot-na 30.83 APE67-dihe-in -80.48, 4.82 -65.53, -29.2 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.6 0.247 0.288 A 310 276 22 0 0 22 [[1078, 1339]] 1.0 3efj Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5DG5A P08581 1050 1346 1390.0 5B4:1401 Type2 Inactive DFGout 15.245 8.981 None -148.03, 172.77 -125.96, 63.08 -65.16, -43.8 189.97, 16.62 73.98, -1.88 in-out in 9.264 Saltbr-out 3.8 HRD-in -77.46, -50.65 83.37, -30.01 out-out-in SNCooi out-in ActLoopNT-out 21.352 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.57, 108.34 APE9-dihe-in -125.39, 83.42 APE8-dihe-in -80.42, 85.64 APE8-rot-na 33.34 APE67-dihe-in -79.25, -5.1 -56.96, -39.29 APE12-dist-na 16.235 APE11-dist-na 16.527 APE10-dist-na 11.188 APE9-dist-in 6.946 None None None XRAY 2.6 0.206 0.245 A 318 297 0 0 0 0 [[1078, 1339]] 1.0 5dg5 Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5DG5B P08581 1050 1346 1390.0 5B4:1401 Type2 Inactive DFGout 15.26 8.971 None -148.45, 172.71 -124.98, 61.77 -64.55, -43.29 189.3, 16.8 74.05, -2.15 in-out in 9.308 Saltbr-out 3.828 HRD-in -77.28, -50.39 83.54, -30.49 out-out-in SNCooi out-in ActLoopNT-out 21.316 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.76, 106.09 APE9-dihe-in -126.22, 85.06 APE8-dihe-in -81.11, 86.98 APE8-rot-na 32.68 APE67-dihe-in -78.84, -4.43 -58.19, -40.13 APE12-dist-na 16.146 APE11-dist-na 16.267 APE10-dist-na 10.94 APE9-dist-in 6.94 None None None XRAY 2.6 0.206 0.245 B 318 297 0 0 0 0 [[1078, 1339]] 1.0 5dg5 Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 7V3RA P08581 1053 1346 1390.0 5IE:1401 Type2 Inactive DFGout 16.131 9.536 None -154.01, 179.09 -125.93, 64.92 -46.8, -55.86 193.46, 7.97 68.82, 17.14 in-out in 8.92 Saltbr-out 3.772 HRD-in -77.59, -50.53 81.74, -18.75 out-out-none SNCoon out-none ActLoopNT-out 15.98 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.44 APE8-dihe-in -82.46, 69.73 APE8-rot-na 32.94 APE67-dihe-in -75.0, -5.3 -63.05, -31.28 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.192 None None None XRAY 1.7 0.169 0.19 A 319 285 9 0 0 8 [[1078, 1339]] 1.0 7v3r Homo sapiens TYR_MET_HUMAN TYR 7.7e-92 313.7 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3CTJA P08581 1051 1360 1390.0 320:2001 Type2 Inactive DFGout 15.628 12.374 None -151.35, -169.91 -155.14, 109.57 -58.4, 999.0 273.45, 76.65 999.0, 999.0 in-in in 8.625 Saltbr-in 3.415 HRD-in -67.75, -57.75 90.09, -21.81 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.13 APE8-dihe-in -85.42, 67.16 APE8-rot-na 33.85 APE67-dihe-in -71.85, -7.28 -60.58, -28.25 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.765 Y1194F,Y1234F,Y1235D None None XRAY 2.5 0.209 0.261 A 314 289 21 0 0 21 [[1078, 1339]] 1.0 3ctj Homo sapiens TYR_MET_HUMAN TYR 8.4e-90 306.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3C1XA P08581 1050 1360 1390.0 CKK:1500 Type2 Inactive DFGout 15.699 8.64 None -151.42, -165.64 -150.75, 113.01 -101.01, 999.0 199.98, 57.96 999.0, 999.0 in-out in 9.454 Saltbr-out 8.485 HRD-in -59.89, -58.33 82.48, -12.42 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.31 APE8-dihe-in -79.79, 76.14 APE8-rot-na 30.37 APE67-dihe-in -67.75, -12.09 -55.44, -37.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.298 Y1194F,Y1234F,Y1235D,L1272L None None XRAY 2.17 0.208 0.262 A 373 290 21 0 0 21 [[1078, 1339]] 1.0 3c1x Homo sapiens TYR_MET_HUMAN TYR 1.5e-89 307.2 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 5T3QA P08581 1050 1350 1390.0 75H:61401 Type1.5_Front Inactive None 999.0 999.0 None -142.6, 175.57 45.45, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 12.187 Saltbr-out 9.495 HRD-in -69.85, -55.7 82.52, -23.62 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 169.98 APE8-dihe-in -92.78, 65.48 APE8-rot-na 37.33 APE67-dihe-in -70.53, -2.22 -62.22, -34.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.582 None None None XRAY 2.0 0.198 0.248 A 309 277 24 0 0 22 [[1078, 1339]] 1.0 5t3q Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.8 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 2RFNA P08581 1057 1351 1390.0 AM7:1 Type1.5_Front Inactive None 999.0 999.0 None -145.52, 173.92 -137.55, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 13.313 Saltbr-out 10.101 HRD-in -80.8, -43.71 73.65, -29.19 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 31.17 APE8-rot-na 23.12 APE67-dihe-in -68.97, -9.97 -50.29, -35.3 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.241 0.294 A 310 268 27 0 0 23 [[1078, 1339]] 1.0 2rfn Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 2RFNB P08581 1056 1351 1390.0 AM7:1 Type1.5_Front Inactive None 999.0 999.0 None -149.27, 171.85 -132.94, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 13.46 Saltbr-out 10.805 HRD-in -77.04, -45.81 74.29, -30.03 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 33.53 APE8-rot-na 35.74 APE67-dihe-in -65.01, -12.86 -49.25, -36.6 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.241 0.294 B 310 269 27 0 0 23 [[1078, 1339]] 1.0 2rfn Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
MET_HUMAN 3EFJB P08581 1054 1351 1390.0 MT3:2 Type1.5_Front Inactive None 999.0 999.0 None -130.74, -175.38 -145.16, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-none out 13.373 Saltbr-none 999.0 HRD-in -71.19, -53.04 82.76, -19.12 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -10.37 APE8-rot-na 31.62 APE67-dihe-in -71.17, -12.51 -66.7, -29.99 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 L1272L None None XRAY 2.6 0.247 0.288 B 310 275 23 0 0 23 [[1078, 1339]] 1.0 3efj Homo sapiens TYR_MET_HUMAN TYR 7e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

TYR_MET (Hepatocyte growth factor receptor)

Total number of chains: 0
Active chains: 0
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name