CAMK_MAPKAPK2 (MAP kinase-activated protein kinase 2)

Total number of chains: 119
Active chains: 2
Uniprot: MAPK2_HUMAN
Kinase Domain Residues: 63 - 325
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 107 89.9% AF-P49137-K1A
DFGin ABAminus 12 10.1% 8XU4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P49137-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 333 0 None None MAP kinase-activated protein kinase 2
AF-P49137-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 333 0 None None MAP kinase-activated protein kinase 2
8XU4A 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2
8XU4B 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2
8XU4C 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 351 0 None S216G MAP kinase-activated protein kinase 2
8XU4D 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 349 0 None S216G MAP kinase-activated protein kinase 2
8XU4E 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2
8XU4F 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2
8XU4G 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2
8XU4H 3.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 47 - 358 0 None S216G MAP kinase-activated protein kinase 2
8XU4I 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 347 0 None S216G MAP kinase-activated protein kinase 2
8XU4J 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 350 0 None S216G MAP kinase-activated protein kinase 2
8XU4K 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2
8XU4L 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 354 0 None S216G MAP kinase-activated protein kinase 2
1NY3A 3.0 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 46 - 345 0 None None MAP kinase-activated protein kinase 2
2PZYD 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nnoo No_ligand No_ligand 43 - 342 0 None None MAP kinase-activated protein kinase 2
4TYHA 3.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 400 0 None None MAP kinase-activated protein kinase 2
2OZAA 2.7 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 390 0 None None MAP kinase-activated protein kinase 2
6TCAA 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 399 0 None None MAP kinase-activated protein kinase 2
6TCAC 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 397 0 None None MAP kinase-activated protein kinase 2
6TCAE 3.7 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 394 0 None None MAP kinase-activated protein kinase 2
6TCAG 3.7 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 397 0 None None MAP kinase-activated protein kinase 2
1KWPA 2.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 46 - 385 0 None None MAP kinase-activated protein kinase 2
1KWPB 2.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 44 - 378 0 None None MAP kinase-activated protein kinase 2
2ONLC 4.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaoio APEdist_oooo No_ligand No_ligand 46 - 393 0 None None MAP kinase-activated protein kinase 2
2ONLD 4.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 46 - 393 0 None None MAP kinase-activated protein kinase 2
3WI6A 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
3WI6B 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
3WI6C 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
3WI6D 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
3WI6E 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
3WI6F 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
3FPMA 3.3 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aanio APEdist_nnnn 793 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
2P3GX 3.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn F10 Type1 45 - 364 0 None None MAP kinase-activated protein kinase 2
3FYJX 3.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn B97 Type1 45 - 364 0 None None MAP kinase-activated protein kinase 2
3FYKX 3.5 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn B98 Type1 45 - 364 0 None None MAP kinase-activated protein kinase 2
7NRYX 3.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn B97 Type1 45 - 366 0 None None MAP kinase-activated protein kinase 2
2JBOA 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo P4O Type1 44 - 347 0 None None MAP kinase-activated protein kinase 2
2JBPL 3.31 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
1NXKD 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nnoo STU Type1 43 - 342 0 None None MAP kinase-activated protein kinase 2
3A2CB 2.9 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 345 0 None None MAP kinase-activated protein kinase 2
3A2CI 2.9 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 343 0 None None MAP kinase-activated protein kinase 2
6T8XA 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno B97, MW8 Type1, Allosteric 44 - 330 0 None T222E,T334E MAP kinase-activated protein kinase 2
6T8XD 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo B97, MW8 Type1, Allosteric 44 - 331 0 None T222E,T334E MAP kinase-activated protein kinase 2
6T8XE 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2
6T8XF 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2
3R2BC 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BD 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BE 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BF 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BG 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BH 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BI 2.9 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BJ 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BK 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BL 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
3KC3G 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 43 - 342 0 None None MAP kinase-activated protein kinase 2
2JBPJ 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 328 0 None None MAP kinase-activated protein kinase 2
8XX1A 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 364 0 None None MAP kinase-activated protein kinase 2
3R2BA 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2BB 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2
3R2YA 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2
3R30A 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn CD2 Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2
2PZYA 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 42 - 346 0 None None MAP kinase-activated protein kinase 2
2PZYB 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
2PZYC 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 359 0 None None MAP kinase-activated protein kinase 2
3KC3A 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 347 0 None None MAP kinase-activated protein kinase 2
3KC3B 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 349 0 None None MAP kinase-activated protein kinase 2
3KC3C 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 41 - 345 0 None None MAP kinase-activated protein kinase 2
3KC3D 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 46 - 342 0 None None MAP kinase-activated protein kinase 2
3KC3E 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
3KC3F 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2
3KC3H 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2
3KC3I 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 45 - 356 0 None None MAP kinase-activated protein kinase 2
3KC3J 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 348 0 None None MAP kinase-activated protein kinase 2
3KC3K 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
3KC3L 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 42 - 348 0 None None MAP kinase-activated protein kinase 2
2JBPA 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
2JBPB 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
2JBPC 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
2JBPD 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 350 0 None None MAP kinase-activated protein kinase 2
2JBPE 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
2JBPF 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2
2JBPG 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2
2JBPH 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
2JBPI 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2
2JBPK 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2
3GOKA 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKB 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKC 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKD 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKE 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKF 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKG 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKH 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKI 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKJ 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKK 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3GOKL 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
3KA0A 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK3 Type1 47 - 364 0 None T222E MAP kinase-activated protein kinase 2
9R59A 3.0 None DFGin‑BLAminus out-none in-none nonTYR APEdihe_aannn APEdist_nnnn A1JH4 Type1 48 - 364 0 None None MAP kinase-activated protein kinase 2
1NXKA 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 345 0 None None MAP kinase-activated protein kinase 2
1NXKB 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
1NXKC 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 41 - 357 0 None None MAP kinase-activated protein kinase 2
3KGAA 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LX9 Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2
3M2WA 2.41 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn L8I Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2
3M42A 2.68 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn HGF Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2
3A2CA 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 344 0 None None MAP kinase-activated protein kinase 2
3A2CC 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 342 0 None None MAP kinase-activated protein kinase 2
3A2CD 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2
3A2CE 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2
3A2CF 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 345 0 None None MAP kinase-activated protein kinase 2
3A2CG 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 342 0 None None MAP kinase-activated protein kinase 2
3A2CH 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 343 0 None None MAP kinase-activated protein kinase 2
3A2CJ 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 343 0 None None MAP kinase-activated protein kinase 2
3A2CK 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2
3A2CL 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2
6T8XB 2.81 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2
6T8XC 2.81 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 44 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2

CAMK_MAPKAPK2 (MAP kinase-activated protein kinase 2)

Total number of chains: 119
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 107 89.9% AF-P49137-K1A
DFGin ABAminus 12 10.1% 8XU4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MAPK2_HUMAN AF-P49137-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 333 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN AF-P49137-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 333 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4A 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4B 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4C 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 351 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4D 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 349 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4E 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4F 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4G 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4H 3.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 47 - 358 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4I 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 347 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4J 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 350 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4K 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XU4L 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 354 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 1NY3A 3.0 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 46 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2PZYD 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nnoo No_ligand No_ligand 43 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 4TYHA 3.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 400 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2OZAA 2.7 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 390 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6TCAA 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 399 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6TCAC 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 397 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6TCAE 3.7 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 394 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6TCAG 3.7 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 51 - 397 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 1KWPA 2.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 46 - 385 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 1KWPB 2.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 44 - 378 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2ONLC 4.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaoio APEdist_oooo No_ligand No_ligand 46 - 393 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2ONLD 4.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 46 - 393 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3WI6A 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3WI6B 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3WI6C 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3WI6D 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3WI6E 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3WI6F 2.99 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn YRZ Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3FPMA 3.3 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aanio APEdist_nnnn 793 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2P3GX 3.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn F10 Type1 45 - 364 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3FYJX 3.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn B97 Type1 45 - 364 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3FYKX 3.5 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn B98 Type1 45 - 364 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 7NRYX 3.8 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn B97 Type1 45 - 366 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBOA 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo P4O Type1 44 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPL 3.31 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 1NXKD 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nnoo STU Type1 43 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CB 2.9 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CI 2.9 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 343 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6T8XA 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno B97, MW8 Type1, Allosteric 44 - 330 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6T8XD 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo B97, MW8 Type1, Allosteric 44 - 331 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6T8XE 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6T8XF 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BC 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BD 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BE 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BF 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BG 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BH 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BI 2.9 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BJ 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BK 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BL 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3G 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 43 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPJ 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 328 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 8XX1A 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 364 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BA 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2BB 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R2YA 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3R30A 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn CD2 Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2PZYA 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 42 - 346 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2PZYB 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2PZYC 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 359 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3A 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3B 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 349 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3C 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 41 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3D 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 46 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3E 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3F 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3H 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3I 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 45 - 356 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3J 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 348 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3K 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KC3L 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 42 - 348 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPA 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPB 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPC 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPD 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPE 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPF 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPG 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPH 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPI 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 2JBPK 3.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKA 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKB 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKC 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKD 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKE 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKF 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKG 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKH 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKI 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKJ 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKK 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3GOKL 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KA0A 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK3 Type1 47 - 364 0 None T222E MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 9R59A 3.0 None DFGin‑BLAminus out-none in-none nonTYR APEdihe_aannn APEdist_nnnn A1JH4 Type1 48 - 364 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 1NXKA 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 1NXKB 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 1NXKC 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 41 - 357 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3KGAA 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LX9 Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3M2WA 2.41 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn L8I Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3M42A 2.68 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn HGF Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CA 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 344 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CC 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CD 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CE 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CF 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CG 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CH 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 47 - 343 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CJ 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 343 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CK 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 3A2CL 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PDY, PDY Type1, Allosteric 48 - 344 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6T8XB 2.81 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens
MAPK2_HUMAN 6T8XC 2.81 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 44 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens

CAMK_MAPKAPK2 (MAP kinase-activated protein kinase 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism