2ONL

MAPK14 (Mitogen-activated protein kinase 14)
MAPKAPK2 (MAP kinase-activated protein kinase 2)
Group: CMGC CAMK
Uniprot: MAPK2_HUMAN MK14_HUMAN
Organism: Homo sapiens
Domain boundary: 63 - 325 24 - 308
Resolution: 4.0

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
C CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 Homo sapiens Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 46 - 393 0
D CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 Homo sapiens Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 46 - 393 0
A CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 Homo sapiens Inactive DFGin BLBminus in-in out-none No_ligand No_ligand 4 - 352 11
B CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 Homo sapiens Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 352 10
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         4         14         24         34 
gshmlemsqE RPTFYRQELN KTIWEVPERY QNLSPVGSGA 
        44         54         64         74 
YGSVCAAFDT KTGLRVAVKK LSRPFQSIIH AKRTYRELRL 
        84         94        104        114 
LKHMKHENVI GLLDVFTPAR SLEEFNDVYL VTHLMGADLN 
       124        134        144        154 
NIVKCQKLTD DHVQFLIYQI LRGLKYIHSA DIIHRDLKPS 
       164        174        184        194 
NLAVNEDCEL KILDFGLARh tddemtgyvA TRWYRAPEIM 
       204        214        224        234 
LNWMHYNQTV DIWSVGCIMA ELLTGRTLFP GTDHIDQLKL 
       244        254        264        274 
ILRLVGTPGA ELLKKISSES ARNYIQSLTQ MPKMNFANVF 
       284        294        304        314 
IGANPLAVDL LEKMLVLDSD KRITAAQALA HAYFAQYHDP 
       324        334        344        354 
DDEPVADPYD QSFESRDLLI DEWKSLTYDE VISFVPPPld 

qeemes
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None