Ligand: LCI

Total number of chains: 4
Active chains: 3
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6GZMA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CK1 CSNK1A1 KC1A_HUMAN 6GZDA 2.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 9 - 305 0 None None Casein kinase I isoform alpha
CK1 CSNK1D KC1D_HUMAN 6GZMA 1.59 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii LCI Type1 5 - 295 0 None R13N Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6GZMB 1.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 1 - 295 0 None R13N Casein kinase I isoform delta
CMGC CDK9 CDK9_HUMAN 6GZHA 3.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 8 - 326 0 TPO186 None Cyclin-dependent kinase 9

Ligand: LCI

Total number of chains: 4
Active chains: 3
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6GZMA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CK1 CSNK1A1 KC1A_HUMAN 6GZDA 2.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 9 - 305 0 None None Casein kinase I isoform alpha Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6GZMA 1.59 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii LCI Type1 5 - 295 0 None R13N Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6GZMB 1.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 1 - 295 0 None R13N Casein kinase I isoform delta Homo sapiens
CMGC CDK9 CDK9_HUMAN 6GZHA 3.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 8 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens

Ligand: LCI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism