| Chain id | Group | Gene | UniprotID | Protein | Organism | Activity | Spatial | Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B | STE | MAP2K1 | MP2K1_HUMAN | Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | AGS LCJ | Type1 Type3 | 43 - 385 | 0 |
| A | TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | AGS | Type1 | 151 - 738 | 0 |
Representative sequence - Chain A
- - 3 13
msyyhhhhhh hhdipttenl yfqgamdmaa lsggggggae
23 33 43 53
pgqalfngdm epeagagaga aassaadpai peevwnikqm
63 73 83 93
ikltqehiea lldkfggehn ppsiyleaye eytskldalq
103 113 123 133
qreqqllesl gngtdfsvss sasmdtvtss sssslsvlps
143 153 163 173
slsvfqnptd varsnpkSPQ KPIVRVFLPN KQRTVVPARC
183 193 203 213
GVTVRDSLKK ALMMRGLIPE CCAVYRIQdg EKKPIGWDTD
223 233 243 253
ISWLTGEELH VEVLENVPLT THNFVRKTFF TLAFCDFCRK
263 273 283 293
LLFQGFRCQT CGYKFHQRCS TEVPLMCVNy dqldllfvsk
303 313 323 333
ffehhpipqe easlaetalt sgsspsapas dsigpqilts
343 353 363 373
pspsksipip qpfrpadedh rnqfgqRDRS SSAPNVHint
383 393 403 413
iepvniddli rdqgfrgdgg sttglsatpp aslpgsltnv
423 433 443 453
kalqkspgpq rerkssssse drnrmktlgr rdssdDWEIP
463 473 483 493
DGQITVGQRI GSGSFGTVYK GKWHGDVAVK MLNVTAPTPQ
503 513 523 533
QLQAFKNEVG VLRKTRHVNI LLFMGYSTKP QLAIVTQWCE
543 553 563 573
GSSLYHHLHI IETKFEMIKL IDIARQTAQG MDYLHAKSII
583 593 603 613
HRDLKSNNIF LHEDLTVKIG DFGLATVKSR WSGSHQFEQL
623 633 643 653
SGSILWMAPE VIRMQDKNPY SFQSDVYAFG IVLYELMTGQ
663 673 683 693
LPYSNINNRD QIIFMVGRGY LSPDLSKVRS NCPKAMKRLM
703 713 723 733
AECLKKKRDE RPLFPQILAS IELLARSLPK IHRSASEPSL
743 753 763 -
NRAGFqtedf slyacaspkt piqaggygaf pvhgtsawsh
pqfek