7MON

MLKL (Mixed lineage kinase domain-like protein)
RIPK3 (Receptor-interacting serine/threonine-protein kinase 3)
Pseudokinase
Group: TKL OTHER
Uniprot: MLKL_HUMAN RIPK3_HUMAN
Organism: Homo sapiens
Domain boundary: 21 - 285 201 - 468
Resolution: 2.23

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B TKL RIPK3 RIPK3_HUMAN Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens Inactive DFGin BLBplus out-out none-out ZL1 Type1.5_Front 5 - 311 12
A OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein Homo sapiens Inactive DFGin BLAplus out-out out-out ZL1 Type1 191 - 469 8
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       194        204        214        224 
gamgsqEQIK EIKKEQLSGS PWILLRENEV STLYKGEYHR 
       234        244        254        264 
APVAIKVFKk lqAGSIAIVR QTFNKEIKTM KKFESPNILR 
       274        284        294        304 
IFGICIDETV TPPQFSIVME YCELGTLREL LDREKDLTLG 
       314        324        334        344 
KRMVLVLGAA RGLYRLHHSE APELHGKIRS SNFLVTQGYQ 
       354        364        374        384 
VKLAGFELRK TQTSMSlgtt rektDRVKST AYLSPQELED 
       394        404        414        424 
VFYQYDVKSE IYSFGIVLWE IATGDIPFQG CNSEKIRKLV 
       434        444        454        464 
AVKRQQEPLG EDCPSELREI IDECRAHDPS VRPSVDEILK 

KLSTFsk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None