RIPK3 (Receptor-interacting serine/threonine-protein kinase 3)

Group: TKL

Uniprot: RIPK3_HUMAN

Domain boundary: 21 - 285

Total number of chains: 6

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	5	AF-Q9Y572-K1A
DFGin	BLBplus	1	7MONB

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-Q9Y572-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	13 - 293	None	None	0
7MX3B	3.23	None	DFGin	BLAminus	in-out	in-none	ZOV	Type1	12 - 309	C3S,C110A	None	16
7MX3A	3.23	None	DFGin	BLAminus	in-in	in-none	ZOV	Type1.5_Back	12 - 314	C3S,C110A	None	10
7MX3C	3.23	None	DFGin	BLAminus	in-in	in-none	ZOV	Type1.5_Back	9 - 311	C3S,C110A	None	10
7MX3D	3.23	None	DFGin	BLAminus	in-in	in-none	ZOV	Type1.5_Back	12 - 311	C3S,C110A	None	14
7MONB	2.23	Inactive	DFGin	BLBplus	out-out	none-out	ZL1	Type1.5_Front	5 - 311	C3S,C110A	X224,X227	12

RIPK3 (Receptor-interacting serine/threonine-protein kinase 3)

Group: TKL

Total number of chains: 11

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	7	AF-Q9Y572-K1A
DFGin	BLBplus	2	4M69A
DFGout	None	2	6OKOA

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	RIPK3_HUMAN	AF-Q9Y572-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	13 - 293	None	None	0
Homo sapiens	RIPK3_HUMAN	7MX3B	3.23	None	DFGin	BLAminus	in-out	in-none	ZOV	Type1	12 - 309	C3S,C110A	None	16
Homo sapiens	RIPK3_HUMAN	7MX3A	3.23	None	DFGin	BLAminus	in-in	in-none	ZOV	Type1.5_Back	12 - 314	C3S,C110A	None	10
Homo sapiens	RIPK3_HUMAN	7MX3C	3.23	None	DFGin	BLAminus	in-in	in-none	ZOV	Type1.5_Back	9 - 311	C3S,C110A	None	10
Homo sapiens	RIPK3_HUMAN	7MX3D	3.23	None	DFGin	BLAminus	in-in	in-none	ZOV	Type1.5_Back	12 - 311	C3S,C110A	None	14
Homo sapiens	RIPK3_HUMAN	7MONB	2.23	Inactive	DFGin	BLBplus	out-out	none-out	ZL1	Type1.5_Front	5 - 311	C3S,C110A	X224,X227	12
Mus musculus	RIPK3_MOUSE	4M66A	2.401	Inactive	DFGin	BLAminus	in-in	in-out	No_ligand	No_ligand	15 - 312	C111A	None	15
Mus musculus	RIPK3_MOUSE	4M66B	2.401	None	DFGin	BLAminus	in-in	in-none	No_ligand	No_ligand	14 - 313	C111A	None	19
Mus musculus	RIPK3_MOUSE	4M69A	2.497	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1	12 - 312	None	X184,X231,X232	14
Mus musculus	RIPK3_MOUSE	6OKOA	2.1	Inactive	DFGout	None	in-in	none-out	1FN	Type2	14 - 311	None	None	23
Mus musculus	RIPK3_MOUSE	6OKOB	2.1	Inactive	DFGout	None	in-out	none-none	1FN	Type2	13 - 311	None	None	25

RIPK3 (Receptor-interacting serine/threonine-protein kinase 3)

Group: TKL

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	2	4M66A
DFGin	BLBplus	1	4M69A
DFGout	None	2	6OKOA

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Mus musculus	RIPK3_MOUSE	4M66A	2.401	Inactive	DFGin	BLAminus	in-in	in-out	No_ligand	No_ligand	15 - 312	C111A	None	15
Mus musculus	RIPK3_MOUSE	4M66B	2.401	None	DFGin	BLAminus	in-in	in-none	No_ligand	No_ligand	14 - 313	C111A	None	19
Mus musculus	RIPK3_MOUSE	4M69A	2.497	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1	12 - 312	None	X184,X231,X232	14
Mus musculus	RIPK3_MOUSE	6OKOA	2.1	Inactive	DFGout	None	in-in	none-out	1FN	Type2	14 - 311	None	None	23
Mus musculus	RIPK3_MOUSE	6OKOB	2.1	Inactive	DFGout	None	in-out	none-none	1FN	Type2	13 - 311	None	None	25