Ligand

Protein kinases in complex with SM5

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	3D4QA
DFGin	None	1	3OMVA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	3D4QA	2.8	Inactive	DFGin	BLAminus	in-in	in-out	SM5	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	3D4QB	2.8	Inactive	DFGin	BLAminus	in-in	in-out	SM5	Type1
TKL	RAF1	RAF1_HUMAN	RAF proto-oncogene serine/threonine-protein kinase	3OMVB	4.0	Inactive	DFGin	BLAminus	in-in	in-out	SM5	Type1
TKL	RAF1	RAF1_HUMAN	RAF proto-oncogene serine/threonine-protein kinase	3OMVA	4.0	Inactive	DFGin	None	in-in	in-out	SM5	Type1

Protein kinases in complex with SM5

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	3D4QA
DFGin	None	1	3OMVA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	3D4QA	2.8	Inactive	DFGin	BLAminus	in-in	in-out	SM5	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	3D4QB	2.8	Inactive	DFGin	BLAminus	in-in	in-out	SM5	Type1
Homo sapiens	TKL	RAF1	RAF1_HUMAN	RAF proto-oncogene serine/threonine-protein kinase	3OMVB	4.0	Inactive	DFGin	BLAminus	in-in	in-out	SM5	Type1
Homo sapiens	TKL	RAF1	RAF1_HUMAN	RAF proto-oncogene serine/threonine-protein kinase	3OMVA	4.0	Inactive	DFGin	None	in-in	in-out	SM5	Type1

Protein kinases in complex with SM5

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type