RAF1 (RAF proto-oncogene serine/threonine-protein kinase)

Group: TKL
Uniprot: RAF1_HUMAN
Domain boundary: 349 - 608


Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 2 AF-P04049-K1A
DFGin None 5 8CHFA
None None 5 8GAED
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P04049-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 341 - 616 None None 0
3OMVB 4.0 Inactive DFGin BLAminus in-in in-out SM5 Type1 340 - 615 None None 12
8CPDA 3.46 Inactive DFGin None in-in in-out No_ligand No_ligand 341 - 626 Y341D X621 12
8CPDB 3.46 Inactive DFGin None in-in in-out No_ligand No_ligand 341 - 626 Y341D X621 12
3OMVA 4.0 Inactive DFGin None in-in in-out SM5 Type1 340 - 615 None None 12
8CHFA 4.25 Inactive DFGin None in-out in-out 29L Type1 341 - 626 Y341D X621 6
8CHFB 4.25 Inactive DFGin None in-out in-out 29L Type1 341 - 626 Y341D X621 6
8GFTD 3.8 Inactive None None none-none none-out No_ligand No_ligand 404 - 611 None None 17
8U1LC 3.7 Inactive None None none-none none-out No_ligand No_ligand 418 - 615 None None 14
7Z37CP1 3.67 Inactive None None none-none none-none No_ligand No_ligand 406 - 615 None None 17
7Z38C 3.16 Inactive None None none-none none-none No_ligand No_ligand 406 - 615 None None 17
8GAED 3.3 Inactive None None none-none none-out No_ligand No_ligand 404 - 610 None None 18

RAF1 (RAF proto-oncogene serine/threonine-protein kinase)

Group: TKL
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 2 AF-P04049-K1A
DFGin None 5 8CHFA
None None 5 8GAED
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens RAF1_HUMAN AF-P04049-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 341 - 616 None None 0
Homo sapiens RAF1_HUMAN 3OMVB 4.0 Inactive DFGin BLAminus in-in in-out SM5 Type1 340 - 615 None None 12
Homo sapiens RAF1_HUMAN 8CPDA 3.46 Inactive DFGin None in-in in-out No_ligand No_ligand 341 - 626 Y341D X621 12
Homo sapiens RAF1_HUMAN 8CPDB 3.46 Inactive DFGin None in-in in-out No_ligand No_ligand 341 - 626 Y341D X621 12
Homo sapiens RAF1_HUMAN 3OMVA 4.0 Inactive DFGin None in-in in-out SM5 Type1 340 - 615 None None 12
Homo sapiens RAF1_HUMAN 8CHFA 4.25 Inactive DFGin None in-out in-out 29L Type1 341 - 626 Y341D X621 6
Homo sapiens RAF1_HUMAN 8CHFB 4.25 Inactive DFGin None in-out in-out 29L Type1 341 - 626 Y341D X621 6
Homo sapiens RAF1_HUMAN 8GFTD 3.8 Inactive None None none-none none-out No_ligand No_ligand 404 - 611 None None 17
Homo sapiens RAF1_HUMAN 8U1LC 3.7 Inactive None None none-none none-out No_ligand No_ligand 418 - 615 None None 14
Homo sapiens RAF1_HUMAN 7Z37CP1 3.67 Inactive None None none-none none-none No_ligand No_ligand 406 - 615 None None 17
Homo sapiens RAF1_HUMAN 7Z38C 3.16 Inactive None None none-none none-none No_ligand No_ligand 406 - 615 None None 17
Homo sapiens RAF1_HUMAN 8GAED 3.3 Inactive None None none-none none-out No_ligand No_ligand 404 - 610 None None 18

RAF1 (RAF proto-oncogene serine/threonine-protein kinase)

No non-human structures known.