Ligand

Protein kinases in complex with H7O

Total number of genes: 2

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	7DHKA
DFGin	BLBplus	2	9EWTA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
CMGC	DYRK2	DYRK2_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 2	7DHKA	2.341	Active	DFGin	BLAminus	in-in	in-in	H7O	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	9EWTA	3.019	Inactive	DFGin	BLBplus	out-out	out-out	A1H7O	Type1.5_Back
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	9EWTB	3.019	Inactive	DFGin	BLBplus	out-out	out-in	A1H7O	Type1.5_Back

Protein kinases in complex with H7O

Total number of genes: 2

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	7DHKA
DFGin	BLBplus	2	9EWTA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	CMGC	DYRK2	DYRK2_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 2	7DHKA	2.341	Active	DFGin	BLAminus	in-in	in-in	H7O	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	9EWTA	3.019	Inactive	DFGin	BLBplus	out-out	out-out	A1H7O	Type1.5_Back
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	9EWTB	3.019	Inactive	DFGin	BLBplus	out-out	out-in	A1H7O	Type1.5_Back

Protein kinases in complex with H7O

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type