Ligand

Protein kinases in complex with CHU (Avutometinib)

Total number of genes: 1

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLBplus	3	3WIGA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3WIGA	2.7	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0ZB	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7MFDB	3.66	Inactive	DFGin	BLBplus	out-out	out-out	CHU	Type3

Protein kinases in complex with CHU

Total number of genes: 1

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLBplus	3	3WIGA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3WIGA	2.7	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0ZB	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7MFDB	3.66	Inactive	DFGin	BLBplus	out-out	out-out	CHU	Type3

Protein kinases in complex with CHU

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type