PDB: 9O0V — 2 kinases

Total number of chains: 8
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 9O0VA
DFGin BLAminus 1 12.5% 9O0VG
DFGin BLAplus 1 12.5% 9O0VE
DFGin BLBminus 1 12.5% 9O0VC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9O0VB Q02750 30 380 393.0 CHU:401,ANP:402 Type1,ATPlike Inactive DFGin 6.1927 14.1253 BLBplus -151.85, 167.5 59.4, 48.24 -102.03, 163.4 46.52, 86.88 -79.89, 84.21 out-out out 15.5955 Saltbr-out 16.8415 HRD-in -72.2, -48.2 74.46, -6.51 out-out-out SNCooo out-out ActLoopNT-out 9.7061 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -135.59, 156.7 APE9-dihe-na -122.67, 146.4 APE8-dihe-out -101.77, -26.6 APE8-rot-in 280.72 APE67-dihe-out -147.98, 135.29 -136.69, 175.09 APE12-dist-out 16.923 APE11-dist-out 17.129 APE10-dist-out 21.8624 APE9-dist-out 12.4292 S218A,S222A None None XRAY 3.5 0.208 0.254 B 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0v STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VH Q02750 30 380 393.0 CHU:401,ANP:402 Type1,ATPlike Inactive DFGin 6.3491 14.2266 BLBplus -152.81, 169.25 61.22, 47.15 -103.13, 164.19 45.91, 94.17 -79.63, 83.31 out-out out 15.6315 Saltbr-out 15.9163 HRD-in -74.73, -48.72 73.54, -6.07 out-out-out SNCooo out-out ActLoopNT-out 9.5069 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -142.21, 151.98 APE9-dihe-na -130.61, 176.34 APE8-dihe-out -105.52, -25.24 APE8-rot-out 37.89 APE67-dihe-out -147.93, 136.16 -136.73, 176.12 APE12-dist-out 17.2775 APE11-dist-out 17.5835 APE10-dist-out 22.1521 APE9-dist-out 13.0006 S218A,S222A None None XRAY 3.5 0.208 0.254 H 395.0 318.0 33 26 26 0 [[68, 361]] 1.0 9o0v STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VD Q02750 31 380 393.0 CHU:401,ANP:402 Type3,ATPlike Inactive DFGin 6.3733 14.325 BLBplus -154.54, 169.16 62.18, 48.49 -103.44, 163.24 44.6, 81.5 -80.27, 83.26 out-out out 16.0835 Saltbr-out 14.6053 HRD-in -72.92, -47.49 72.01, -5.54 out-out-out SNCooo out-out ActLoopNT-out 9.4975 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -145.24, 151.58 APE9-dihe-na -129.14, 150.7 APE8-dihe-out -101.27, -25.48 APE8-rot-in 295.39 APE67-dihe-out -149.5, 133.8 -134.87, 174.51 APE12-dist-out 17.6813 APE11-dist-out 17.5865 APE10-dist-out 22.6132 APE9-dist-out 12.7344 S218A,S222A None None XRAY 3.5 0.208 0.254 D 395.0 315.0 35 26 26 0 [[68, 361]] 1.0 9o0v STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VF Q02750 30 380 393.0 CHU:401,ANP:402 Type3,ATPlike Inactive DFGin 6.3482 14.2973 BLBplus -150.02, 162.92 66.4, 48.22 -102.89, 163.79 46.62, 89.05 -79.32, 84.9 out-out out 15.5104 Saltbr-out 15.8816 HRD-in -75.24, -46.98 72.8, -6.4 out-out-out SNCooo out-out ActLoopNT-out 9.801 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -127.4, 126.99 APE9-dihe-na -155.92, 117.08 APE8-dihe-out -98.23, -9.95 APE8-rot-in 320.72 APE67-dihe-out -148.49, 134.6 -133.67, 172.28 APE12-dist-out 18.6736 APE11-dist-out 16.7401 APE10-dist-out 21.3436 APE9-dist-out 12.7026 S218A,S222A None None XRAY 3.5 0.208 0.254 F 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0v STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9O0VG P04049 341 614 648.0 324:701 Type1 Inactive DFGin 6.6518 14.5256 BLAminus -136.91, -164.75 63.88, 58.79 -91.51, 23.22 298.64, 111.76 -69.75, -22.63 in-in in 8.5288 Saltbr-in 2.8267 HRD-in -68.13, -46.19 73.7, -5.88 in-in-out SNCiio in-out ActLoopNT-in 3.3624 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -144.93, -171.41 APE9-dihe-na 95.72, -110.34 APE8-dihe-in -121.89, 159.4 APE8-rot-out 179.42 APE67-dihe-in -62.17, -27.08 -108.22, -7.65 APE12-dist-in 9.3788 APE11-dist-in 8.988 APE10-dist-out 10.4038 APE9-dist-out 9.6609 Y340D,Y341D None None XRAY 3.5 0.208 0.254 G 280.0 265.0 9 30 21 9 [[349, 608]] 1.0 9o0v TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VE P04049 339 613 648.0 324:701 Type1.5_Back Inactive DFGin 5.8024 13.3404 BLAplus -138.88, -169.03 61.87, 34.79 -104.64, 32.35 56.09, 93.36 -64.43, -47.67 out-none out 11.5845 Saltbr-none 999.0 HRD-in -66.6, -47.0 72.05, -8.97 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na 56.8, 24.32 APE9-dihe-na -101.33, -80.31 APE8-dihe-in -132.61, 160.7 APE8-rot-out 180.75 APE67-dihe-in -62.26, -27.57 -106.96, -6.66 APE12-dist-in 11.2624 APE11-dist-in 9.0411 APE10-dist-out 12.024 APE9-dist-out 9.4519 Y340D,Y341D None None XRAY 3.5 0.208 0.254 E 280.0 261.0 14 30 16 14 [[349, 608]] 1.0 9o0v TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VC P04049 339 614 648.0 324:701 Type1 Inactive DFGin 6.507 14.8484 BLBminus -135.62, -163.14 65.12, 48.02 -88.94, 153.23 304.77, 118.58 148.73, -35.99 in-in in 8.1644 Saltbr-in 3.3442 HRD-in -65.49, -42.82 73.84, -8.92 in-in-out SNCiio in-out ActLoopNT-in 3.3433 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -150.01 APE9-dihe-na 93.34, -107.4 APE8-dihe-in -126.38, 163.35 APE8-rot-out 180.01 APE67-dihe-in -65.89, -28.16 -108.44, -15.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.4019 APE9-dist-out 7.9115 Y340D,Y341D None None XRAY 3.5 0.208 0.254 C 280.0 264.0 12 30 18 12 [[349, 608]] 1.0 9o0v TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VA P04049 339 612 648.0 324:701 Type1.5_Back Inactive DFGin 5.6121 13.5412 BLBplus -137.53, -168.14 60.68, 23.81 -97.37, 165.11 62.5, 93.91 74.63, 173.9 out-none out 11.5178 Saltbr-none 999.0 HRD-in -67.23, -47.12 72.36, -10.39 none-out-out SNCnoo out-out ActLoopNT-out 8.5821 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -121.31, 23.23 APE9-dihe-na -94.2, -61.86 APE8-dihe-in -150.39, 162.26 APE8-rot-out 181.1 APE67-dihe-in -63.35, -28.52 -106.79, -7.22 APE12-dist-out 14.0563 APE11-dist-in 11.3326 APE10-dist-out 13.0181 APE9-dist-out 9.5213 Y340D,Y341D None None XRAY 3.5 0.208 0.254 A 280.0 266.0 8 30 22 8 [[349, 608]] 1.0 9o0v TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9O0V — 2 kinases

Total number of chains: 8
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 9O0VA
DFGin BLAminus 1 12.5% 9O0VG
DFGin BLAplus 1 12.5% 9O0VE
DFGin BLBminus 1 12.5% 9O0VC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9O0VB Q02750 30 380 393.0 CHU:401,ANP:402 Type1,ATPlike Inactive DFGin 6.1927 14.1253 BLBplus -151.85, 167.5 59.4, 48.24 -102.03, 163.4 46.52, 86.88 -79.89, 84.21 out-out out 15.5955 Saltbr-out 16.8415 HRD-in -72.2, -48.2 74.46, -6.51 out-out-out SNCooo out-out ActLoopNT-out 9.7061 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -135.59, 156.7 APE9-dihe-na -122.67, 146.4 APE8-dihe-out -101.77, -26.6 APE8-rot-in 280.72 APE67-dihe-out -147.98, 135.29 -136.69, 175.09 APE12-dist-out 16.923 APE11-dist-out 17.129 APE10-dist-out 21.8624 APE9-dist-out 12.4292 S218A,S222A None None XRAY 3.5 0.208 0.254 B 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0v Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VH Q02750 30 380 393.0 CHU:401,ANP:402 Type1,ATPlike Inactive DFGin 6.3491 14.2266 BLBplus -152.81, 169.25 61.22, 47.15 -103.13, 164.19 45.91, 94.17 -79.63, 83.31 out-out out 15.6315 Saltbr-out 15.9163 HRD-in -74.73, -48.72 73.54, -6.07 out-out-out SNCooo out-out ActLoopNT-out 9.5069 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -142.21, 151.98 APE9-dihe-na -130.61, 176.34 APE8-dihe-out -105.52, -25.24 APE8-rot-out 37.89 APE67-dihe-out -147.93, 136.16 -136.73, 176.12 APE12-dist-out 17.2775 APE11-dist-out 17.5835 APE10-dist-out 22.1521 APE9-dist-out 13.0006 S218A,S222A None None XRAY 3.5 0.208 0.254 H 395.0 318.0 33 26 26 0 [[68, 361]] 1.0 9o0v Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VD Q02750 31 380 393.0 CHU:401,ANP:402 Type3,ATPlike Inactive DFGin 6.3733 14.325 BLBplus -154.54, 169.16 62.18, 48.49 -103.44, 163.24 44.6, 81.5 -80.27, 83.26 out-out out 16.0835 Saltbr-out 14.6053 HRD-in -72.92, -47.49 72.01, -5.54 out-out-out SNCooo out-out ActLoopNT-out 9.4975 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -145.24, 151.58 APE9-dihe-na -129.14, 150.7 APE8-dihe-out -101.27, -25.48 APE8-rot-in 295.39 APE67-dihe-out -149.5, 133.8 -134.87, 174.51 APE12-dist-out 17.6813 APE11-dist-out 17.5865 APE10-dist-out 22.6132 APE9-dist-out 12.7344 S218A,S222A None None XRAY 3.5 0.208 0.254 D 395.0 315.0 35 26 26 0 [[68, 361]] 1.0 9o0v Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VF Q02750 30 380 393.0 CHU:401,ANP:402 Type3,ATPlike Inactive DFGin 6.3482 14.2973 BLBplus -150.02, 162.92 66.4, 48.22 -102.89, 163.79 46.62, 89.05 -79.32, 84.9 out-out out 15.5104 Saltbr-out 15.8816 HRD-in -75.24, -46.98 72.8, -6.4 out-out-out SNCooo out-out ActLoopNT-out 9.801 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -127.4, 126.99 APE9-dihe-na -155.92, 117.08 APE8-dihe-out -98.23, -9.95 APE8-rot-in 320.72 APE67-dihe-out -148.49, 134.6 -133.67, 172.28 APE12-dist-out 18.6736 APE11-dist-out 16.7401 APE10-dist-out 21.3436 APE9-dist-out 12.7026 S218A,S222A None None XRAY 3.5 0.208 0.254 F 395.0 322.0 29 26 26 0 [[68, 361]] 1.0 9o0v Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9O0VG P04049 341 614 648.0 324:701 Type1 Inactive DFGin 6.6518 14.5256 BLAminus -136.91, -164.75 63.88, 58.79 -91.51, 23.22 298.64, 111.76 -69.75, -22.63 in-in in 8.5288 Saltbr-in 2.8267 HRD-in -68.13, -46.19 73.7, -5.88 in-in-out SNCiio in-out ActLoopNT-in 3.3624 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -144.93, -171.41 APE9-dihe-na 95.72, -110.34 APE8-dihe-in -121.89, 159.4 APE8-rot-out 179.42 APE67-dihe-in -62.17, -27.08 -108.22, -7.65 APE12-dist-in 9.3788 APE11-dist-in 8.988 APE10-dist-out 10.4038 APE9-dist-out 9.6609 Y340D,Y341D None None XRAY 3.5 0.208 0.254 G 280.0 265.0 9 30 21 9 [[349, 608]] 1.0 9o0v Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VE P04049 339 613 648.0 324:701 Type1.5_Back Inactive DFGin 5.8024 13.3404 BLAplus -138.88, -169.03 61.87, 34.79 -104.64, 32.35 56.09, 93.36 -64.43, -47.67 out-none out 11.5845 Saltbr-none 999.0 HRD-in -66.6, -47.0 72.05, -8.97 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na 56.8, 24.32 APE9-dihe-na -101.33, -80.31 APE8-dihe-in -132.61, 160.7 APE8-rot-out 180.75 APE67-dihe-in -62.26, -27.57 -106.96, -6.66 APE12-dist-in 11.2624 APE11-dist-in 9.0411 APE10-dist-out 12.024 APE9-dist-out 9.4519 Y340D,Y341D None None XRAY 3.5 0.208 0.254 E 280.0 261.0 14 30 16 14 [[349, 608]] 1.0 9o0v Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VC P04049 339 614 648.0 324:701 Type1 Inactive DFGin 6.507 14.8484 BLBminus -135.62, -163.14 65.12, 48.02 -88.94, 153.23 304.77, 118.58 148.73, -35.99 in-in in 8.1644 Saltbr-in 3.3442 HRD-in -65.49, -42.82 73.84, -8.92 in-in-out SNCiio in-out ActLoopNT-in 3.3433 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -150.01 APE9-dihe-na 93.34, -107.4 APE8-dihe-in -126.38, 163.35 APE8-rot-out 180.01 APE67-dihe-in -65.89, -28.16 -108.44, -15.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.4019 APE9-dist-out 7.9115 Y340D,Y341D None None XRAY 3.5 0.208 0.254 C 280.0 264.0 12 30 18 12 [[349, 608]] 1.0 9o0v Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VA P04049 339 612 648.0 324:701 Type1.5_Back Inactive DFGin 5.6121 13.5412 BLBplus -137.53, -168.14 60.68, 23.81 -97.37, 165.11 62.5, 93.91 74.63, 173.9 out-none out 11.5178 Saltbr-none 999.0 HRD-in -67.23, -47.12 72.36, -10.39 none-out-out SNCnoo out-out ActLoopNT-out 8.5821 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -121.31, 23.23 APE9-dihe-na -94.2, -61.86 APE8-dihe-in -150.39, 162.26 APE8-rot-out 181.1 APE67-dihe-in -63.35, -28.52 -106.79, -7.22 APE12-dist-out 14.0563 APE11-dist-in 11.3326 APE10-dist-out 13.0181 APE9-dist-out 9.5213 Y340D,Y341D None None XRAY 3.5 0.208 0.254 A 280.0 266.0 8 30 22 8 [[349, 608]] 1.0 9o0v Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9O0V — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name