PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8TO3A
DFGin BLBtrans 2 50.0% 8TO3D

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao IXC Type1.5_Front 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor

PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8TO3A
DFGin BLBtrans 2 50.0% 8TO3D

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao IXC Type1.5_Front 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism