PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV3A
DFGin BLBtrans 2 50.0% 8FV3B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YA6 Type1.5_Back 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3B 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3D 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor

PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV3A
DFGin BLBtrans 2 50.0% 8FV3B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YA6 Type1.5_Back 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3B 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3D 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism