PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV3A
DFGin BLBtrans 2 50.0% 8FV3B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8FV3A P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 3.9601 13.3971 BLBplus -132.16, 169.96 65.72, 32.0 -78.17, 140.3 56.84, 82.43 67.0, 6.27 out-out out 13.5436 Saltbr-out 14.7322 HRD-in -69.71, -62.71 86.1, -12.85 out-out-none SNCoon out-none ActLoopNT-out 6.5423 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 27.23 APE9-dihe-in -63.25, 122.03 APE8-dihe-in -75.98, 67.82 APE8-rot-na 29.66 APE67-dihe-in -76.37, -3.74 -56.38, -36.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.7262 APE9-dist-in 7.9867 T790M,V948R None None XRAY 2.1 0.191 0.226 A 328.0 299.0 14 30 18 12 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C P00533 701 1009 1210.0 YA6:1101 Type1.5_Back Inactive DFGin 4.9759 14.2258 BLBplus -140.28, 173.45 62.97, 49.98 -100.77, 147.39 44.76, 100.07 103.45, -165.1 out-out out 13.7327 Saltbr-out 12.9767 HRD-in -73.54, -54.95 81.69, -9.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 112.62 APE8-dihe-in -78.9, 67.7 APE8-rot-na 28.92 APE67-dihe-in -74.17, -1.93 -55.66, -42.6 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.2065 T790M,V948R None None XRAY 2.1 0.191 0.226 C 328.0 291.0 18 30 13 17 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3B P00533 701 1021 1210.0 ANP:1102 ATPlike Inactive DFGin 5.4387 16.4957 BLBtrans -118.64, 177.37 63.4, 20.55 -58.75, 145.81 159.38, 77.34 77.7, -11.94 out-out out 13.9071 Saltbr-out 12.6093 HRD-in -79.27, -57.12 85.07, -16.18 out-out-none SNCoon out-none ActLoopNT-out 6.5505 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -85.47 APE9-dihe-in -94.5, 111.51 APE8-dihe-in -78.45, 79.51 APE8-rot-na 26.67 APE67-dihe-in -72.96, -7.53 -57.83, -45.1 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.1584 APE9-dist-in 7.6087 T790M,V948R None None XRAY 2.1 0.191 0.226 B 328.0 307.0 12 30 18 12 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3D P00533 701 1008 1210.0 ANP:1102 ATPlike Inactive DFGin 5.123 16.0686 BLBtrans -118.91, 178.66 63.22, 20.1 -58.76, 136.59 151.59, 72.8 86.53, -14.56 out-out out 13.6355 Saltbr-out 11.8782 HRD-in -77.73, -54.76 83.51, -15.49 out-out-none SNCoon out-none ActLoopNT-out 6.6865 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -35.35 APE9-dihe-in -75.26, 139.37 APE8-dihe-in -77.41, 75.08 APE8-rot-na 30.35 APE67-dihe-in -77.52, -1.37 -56.44, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.9892 APE9-dist-in 7.8559 T790M,V948R None None XRAY 2.1 0.191 0.226 D 328.0 295.0 13 30 18 12 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV3A
DFGin BLBtrans 2 50.0% 8FV3B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8FV3A P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 3.9601 13.3971 BLBplus -132.16, 169.96 65.72, 32.0 -78.17, 140.3 56.84, 82.43 67.0, 6.27 out-out out 13.5436 Saltbr-out 14.7322 HRD-in -69.71, -62.71 86.1, -12.85 out-out-none SNCoon out-none ActLoopNT-out 6.5423 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 27.23 APE9-dihe-in -63.25, 122.03 APE8-dihe-in -75.98, 67.82 APE8-rot-na 29.66 APE67-dihe-in -76.37, -3.74 -56.38, -36.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.7262 APE9-dist-in 7.9867 T790M,V948R None None XRAY 2.1 0.191 0.226 A 328.0 299.0 14 30 18 12 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C P00533 701 1009 1210.0 YA6:1101 Type1.5_Back Inactive DFGin 4.9759 14.2258 BLBplus -140.28, 173.45 62.97, 49.98 -100.77, 147.39 44.76, 100.07 103.45, -165.1 out-out out 13.7327 Saltbr-out 12.9767 HRD-in -73.54, -54.95 81.69, -9.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 112.62 APE8-dihe-in -78.9, 67.7 APE8-rot-na 28.92 APE67-dihe-in -74.17, -1.93 -55.66, -42.6 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.2065 T790M,V948R None None XRAY 2.1 0.191 0.226 C 328.0 291.0 18 30 13 17 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3B P00533 701 1021 1210.0 ANP:1102 ATPlike Inactive DFGin 5.4387 16.4957 BLBtrans -118.64, 177.37 63.4, 20.55 -58.75, 145.81 159.38, 77.34 77.7, -11.94 out-out out 13.9071 Saltbr-out 12.6093 HRD-in -79.27, -57.12 85.07, -16.18 out-out-none SNCoon out-none ActLoopNT-out 6.5505 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -85.47 APE9-dihe-in -94.5, 111.51 APE8-dihe-in -78.45, 79.51 APE8-rot-na 26.67 APE67-dihe-in -72.96, -7.53 -57.83, -45.1 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.1584 APE9-dist-in 7.6087 T790M,V948R None None XRAY 2.1 0.191 0.226 B 328.0 307.0 12 30 18 12 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3D P00533 701 1008 1210.0 ANP:1102 ATPlike Inactive DFGin 5.123 16.0686 BLBtrans -118.91, 178.66 63.22, 20.1 -58.76, 136.59 151.59, 72.8 86.53, -14.56 out-out out 13.6355 Saltbr-out 11.8782 HRD-in -77.73, -54.76 83.51, -15.49 out-out-none SNCoon out-none ActLoopNT-out 6.6865 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -35.35 APE9-dihe-in -75.26, 139.37 APE8-dihe-in -77.41, 75.08 APE8-rot-na 30.35 APE67-dihe-in -77.52, -1.37 -56.44, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.9892 APE9-dist-in 7.8559 T790M,V948R None None XRAY 2.1 0.191 0.226 D 328.0 295.0 13 30 18 12 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name