PDB: 4UX9 — CMGC MK08_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 4UX9A
DFGin None 1 25.0% 4UX9B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 4UX9A P45983 8 363 427.0 ANP:1000 ATPlike Inactive DFGin 6.5081 13.5979 ABAminus -106.9, -65.56 -75.5, 125.74 -123.36, 16.47 304.33, 124.23 -68.62, -34.25 in-out in 8.8495 Saltbr-out 3.6733 HRD-in -62.88, -46.37 73.76, -28.18 out-in-in SNCoii in-in ActLoopNT-in 2.694 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -77.3, -23.46 APE9-dihe-na -71.58, 140.2 APE8-dihe-in -64.86, 127.48 APE8-rot-in 308.5 APE67-dihe-in -60.43, -26.76 -33.69, -61.49 APE12-dist-in 11.784 APE11-dist-in 12.4258 APE10-dist-in 6.6314 APE9-dist-in 4.5326 None None None XRAY 2.34 0.202 0.24 A 364.0 343.0 7 27 22 5 [[26, 321]] 1.0 4ux9 CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9C P45983 8 363 427.0 ANP:1000 ATPlike Inactive DFGin 6.9564 13.7764 ABAminus -110.49, -64.95 -89.1, 120.63 -119.14, 21.23 309.02, 115.06 -68.23, -26.49 in-out in 8.9193 Saltbr-out 3.6356 HRD-in -66.22, -47.15 71.23, -16.82 out-in-none SNCoin in-none ActLoopNT-in 2.5691 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -79.69, -26.4 APE9-dihe-na -76.07, 142.18 APE8-dihe-in -66.37, 127.01 APE8-rot-in 305.02 APE67-dihe-in -64.57, -24.76 -35.27, -55.26 APE12-dist-none 999.0 APE11-dist-in 12.0054 APE10-dist-in 6.5305 APE9-dist-in 4.6212 None None None XRAY 2.34 0.202 0.24 C 364.0 333.0 15 27 20 7 [[26, 321]] 1.0 4ux9 CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9D P45983 9 364 427.0 ANP:1000 ATPlike Inactive DFGin 6.7553 13.4065 ABAminus -120.6, -55.98 -93.07, 108.1 -98.68, 25.97 301.07, 117.04 -64.8, -33.9 in-in in 9.3656 Saltbr-in 2.7382 HRD-in -59.8, -49.61 70.57, -12.64 in-in-out SNCiio in-out ActLoopNT-in 2.6695 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oioo APE10-dihe-na -95.31, 105.19 APE9-dihe-na -74.34, -56.46 APE8-dihe-in -76.71, 134.72 APE8-rot-out 95.68 APE67-dihe-out -66.63, -26.9 -139.86, 50.27 APE12-dist-out 14.0313 APE11-dist-in 13.438 APE10-dist-out 10.8234 APE9-dist-out 13.5554 None None None XRAY 2.34 0.202 0.24 D 364.0 344.0 9 27 27 0 [[26, 321]] 1.0 4ux9 CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9B P45983 8 362 427.0 ANP:1000 ATPlike Inactive DFGin 6.8269 14.0009 None -95.23, -79.97 -82.17, 124.02 -113.22, 13.68 297.81, 107.19 -60.29, -32.64 in-in in 8.6029 Saltbr-in 2.9418 HRD-in -59.44, -53.0 79.08, -24.85 in-in-in SNCiii in-in ActLoopNT-in 2.5822 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -58.47, -40.48 APE9-dihe-na -78.17, 138.93 APE8-dihe-in -64.59, 122.35 APE8-rot-in 308.57 APE67-dihe-in -67.83, -19.56 -32.59, -57.13 APE12-dist-in 12.3608 APE11-dist-in 12.1486 APE10-dist-in 6.5271 APE9-dist-in 4.6911 None None None XRAY 2.34 0.202 0.24 B 364.0 327.0 14 27 21 6 [[26, 321]] 1.0 4ux9 CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 4UX9 — CMGC MK08_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 4UX9A
DFGin None 1 25.0% 4UX9B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 4UX9A P45983 8 363 427.0 ANP:1000 ATPlike Inactive DFGin 6.5081 13.5979 ABAminus -106.9, -65.56 -75.5, 125.74 -123.36, 16.47 304.33, 124.23 -68.62, -34.25 in-out in 8.8495 Saltbr-out 3.6733 HRD-in -62.88, -46.37 73.76, -28.18 out-in-in SNCoii in-in ActLoopNT-in 2.694 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -77.3, -23.46 APE9-dihe-na -71.58, 140.2 APE8-dihe-in -64.86, 127.48 APE8-rot-in 308.5 APE67-dihe-in -60.43, -26.76 -33.69, -61.49 APE12-dist-in 11.784 APE11-dist-in 12.4258 APE10-dist-in 6.6314 APE9-dist-in 4.5326 None None None XRAY 2.34 0.202 0.24 A 364.0 343.0 7 27 22 5 [[26, 321]] 1.0 4ux9 Homo sapiens CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9C P45983 8 363 427.0 ANP:1000 ATPlike Inactive DFGin 6.9564 13.7764 ABAminus -110.49, -64.95 -89.1, 120.63 -119.14, 21.23 309.02, 115.06 -68.23, -26.49 in-out in 8.9193 Saltbr-out 3.6356 HRD-in -66.22, -47.15 71.23, -16.82 out-in-none SNCoin in-none ActLoopNT-in 2.5691 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -79.69, -26.4 APE9-dihe-na -76.07, 142.18 APE8-dihe-in -66.37, 127.01 APE8-rot-in 305.02 APE67-dihe-in -64.57, -24.76 -35.27, -55.26 APE12-dist-none 999.0 APE11-dist-in 12.0054 APE10-dist-in 6.5305 APE9-dist-in 4.6212 None None None XRAY 2.34 0.202 0.24 C 364.0 333.0 15 27 20 7 [[26, 321]] 1.0 4ux9 Homo sapiens CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9D P45983 9 364 427.0 ANP:1000 ATPlike Inactive DFGin 6.7553 13.4065 ABAminus -120.6, -55.98 -93.07, 108.1 -98.68, 25.97 301.07, 117.04 -64.8, -33.9 in-in in 9.3656 Saltbr-in 2.7382 HRD-in -59.8, -49.61 70.57, -12.64 in-in-out SNCiio in-out ActLoopNT-in 2.6695 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oioo APE10-dihe-na -95.31, 105.19 APE9-dihe-na -74.34, -56.46 APE8-dihe-in -76.71, 134.72 APE8-rot-out 95.68 APE67-dihe-out -66.63, -26.9 -139.86, 50.27 APE12-dist-out 14.0313 APE11-dist-in 13.438 APE10-dist-out 10.8234 APE9-dist-out 13.5554 None None None XRAY 2.34 0.202 0.24 D 364.0 344.0 9 27 27 0 [[26, 321]] 1.0 4ux9 Homo sapiens CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9B P45983 8 362 427.0 ANP:1000 ATPlike Inactive DFGin 6.8269 14.0009 None -95.23, -79.97 -82.17, 124.02 -113.22, 13.68 297.81, 107.19 -60.29, -32.64 in-in in 8.6029 Saltbr-in 2.9418 HRD-in -59.44, -53.0 79.08, -24.85 in-in-in SNCiii in-in ActLoopNT-in 2.5822 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -58.47, -40.48 APE9-dihe-na -78.17, 138.93 APE8-dihe-in -64.59, 122.35 APE8-rot-in 308.57 APE67-dihe-in -67.83, -19.56 -32.59, -57.13 APE12-dist-in 12.3608 APE11-dist-in 12.1486 APE10-dist-in 6.5271 APE9-dist-in 4.6911 None None None XRAY 2.34 0.202 0.24 B 364.0 327.0 14 27 21 6 [[26, 321]] 1.0 4ux9 Homo sapiens CMGC_MAPK8_HUMAN CMGC 4.3e-84 288.2 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 4UX9 — CMGC MK08_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name