PDB: 4H58 — TKL BRAF_HUMAN

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 33.3% 4H58B
DFGin None 1 33.3% 4H58A
DFGout BBAminus 1 33.3% 4H58C

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL BRAF BRAF_HUMAN 4H58B 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4H58A 3.1 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 10Z Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4H58C 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf

PDB: 4H58 — TKL BRAF_HUMAN

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 33.3% 4H58B
DFGin None 1 33.3% 4H58A
DFGout BBAminus 1 33.3% 4H58C

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL BRAF BRAF_HUMAN 4H58B 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4H58A 3.1 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 10Z Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4H58C 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens

PDB: 4H58 — TKL BRAF_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism