Ligand: YDJ

Total number of chains: 6
Active chains: 3
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 50.0% 4W9WA
DFGin BLBplus 2 33.3% 7CQEA
DFGin None 1 16.7% 5WILA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK CHEK1 CHK1_HUMAN 2YDJA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 8 - 269 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 2YDJB 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 9 - 269 0 None None Serine/threonine-protein kinase Chk1
OTHER BMP2K BMP2K_HUMAN 4W9WA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ, YDJ Type1, Allosteric 39 - 344 0 None K320A,K321A BMP-2-inducible protein kinase
TYR JAK2-1 JAK2_HUMAN 5WILA 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao YDJ Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR MERTK MERTK_HUMAN 7CQEA 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7CQEC 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer

Ligand: YDJ

Total number of chains: 6
Active chains: 3
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 50.0% 4W9WA
DFGin BLBplus 2 33.3% 7CQEA
DFGin None 1 16.7% 5WILA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK CHEK1 CHK1_HUMAN 2YDJA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 8 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 2YDJB 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 9 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
OTHER BMP2K BMP2K_HUMAN 4W9WA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ, YDJ Type1, Allosteric 39 - 344 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5WILA 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao YDJ Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR MERTK MERTK_HUMAN 7CQEA 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7CQEC 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens

Ligand: YDJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism