Ligand: VO7

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 60.0% 7JXLB
DFGin BLAminus 1 20.0% 9NM0A
DFGin BLBtrans 1 20.0% 7JXLA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9NM0A P00533 697 1018 1210.0 VO7:1101 Type1 None DFGin 6.308 15.402 BLAminus -140.17, -167.49 58.79, 90.01 -111.11, 22.07 294.08, 94.65 -58.39, -24.66 in-in in 8.079 Saltbr-in 3.12 HRD-in -72.56, -49.62 74.29, -11.19 in-in-none SNCiin in-none ActLoopNT-in 2.75 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 98.9 APE8-rot-na 32.89 APE67-dihe-in -82.2, -4.65 -68.26, -37.96 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.59 0.209 0.247 A 327 273 27 0 0 16 [[712, 970]] 1.0 9nm0 TYR_EGFR_HUMAN TYR 1e-87 299.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLB P00533 700 1005 1210.0 VO7:1101 Type1 Inactive DFGin 5.246 13.632 BLBplus -132.57, 173.49 63.97, 37.87 -98.02, 155.82 53.78, 87.52 97.69, 168.21 out-out out 13.274 Saltbr-out 10.365 HRD-in -68.45, -55.65 82.41, -9.47 out-out-none SNCoon out-none ActLoopNT-out 11.071 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 148.84 APE8-dihe-in -79.09, 72.8 APE8-rot-na 32.94 APE67-dihe-in -75.09, -2.58 -53.56, -42.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.945 T790M,V948R None None XRAY 2.4 0.21 0.239 B 331 285 15 0 0 15 [[712, 970]] 1.0 7jxl TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLC P00533 700 1007 1210.0 VO7:1101 Type1 Inactive DFGin 5.046 14.21 BLBplus -131.44, 169.42 60.64, 42.48 -100.4, 172.86 57.82, 96.69 101.73, -98.55 out-out out 13.295 Saltbr-out 10.82 HRD-in -68.59, -57.74 83.98, -10.65 out-out-out SNCooo out-out ActLoopNT-out 8.773 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 148.84 APE8-dihe-in -84.48, 72.12 APE8-rot-na 33.75 APE67-dihe-in -77.24, -3.14 -52.76, -40.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.068 T790M,V948R None None XRAY 2.4 0.21 0.239 C 331 292 16 0 0 14 [[712, 970]] 1.0 7jxl TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLD P00533 700 1007 1210.0 VO7:1101 Type1 Inactive DFGin 5.173 13.928 BLBplus -133.7, 169.87 61.73, 43.83 -103.39, 170.74 58.35, 94.82 87.82, 34.82 out-out out 13.626 Saltbr-out 11.064 HRD-in -67.75, -57.45 83.8, -10.92 out-out-none SNCoon out-none ActLoopNT-out 9.169 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 68.84 APE8-rot-na 32.75 APE67-dihe-in -76.98, -2.85 -51.41, -42.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 2.4 0.21 0.239 D 331 292 16 0 0 16 [[712, 970]] 1.0 7jxl TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLA P00533 701 1013 1210.0 VO7:1101 Type1 Inactive DFGin 5.542 16.067 BLBtrans -126.4, -179.97 66.03, 31.68 -87.54, 145.45 161.25, 72.83 92.56, -6.61 out-out out 13.282 Saltbr-out 13.233 HRD-in -72.85, -58.8 84.46, -15.1 out-out-none SNCoon out-none ActLoopNT-out 9.348 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 142.61 APE8-dihe-in -82.4, 69.83 APE8-rot-na 33.22 APE67-dihe-in -77.96, -2.7 -53.21, -40.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.765 T790M,V948R None None XRAY 2.4 0.21 0.239 A 331 294 19 0 0 14 [[712, 970]] 1.0 7jxl TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: VO7

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 60.0% 7JXLB
DFGin BLAminus 1 20.0% 9NM0A
DFGin BLBtrans 1 20.0% 7JXLA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9NM0A P00533 697 1018 1210.0 VO7:1101 Type1 None DFGin 6.308 15.402 BLAminus -140.17, -167.49 58.79, 90.01 -111.11, 22.07 294.08, 94.65 -58.39, -24.66 in-in in 8.079 Saltbr-in 3.12 HRD-in -72.56, -49.62 74.29, -11.19 in-in-none SNCiin in-none ActLoopNT-in 2.75 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 98.9 APE8-rot-na 32.89 APE67-dihe-in -82.2, -4.65 -68.26, -37.96 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.59 0.209 0.247 A 327 273 27 0 0 16 [[712, 970]] 1.0 9nm0 Homo sapiens TYR_EGFR_HUMAN TYR 1e-87 299.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLB P00533 700 1005 1210.0 VO7:1101 Type1 Inactive DFGin 5.246 13.632 BLBplus -132.57, 173.49 63.97, 37.87 -98.02, 155.82 53.78, 87.52 97.69, 168.21 out-out out 13.274 Saltbr-out 10.365 HRD-in -68.45, -55.65 82.41, -9.47 out-out-none SNCoon out-none ActLoopNT-out 11.071 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 148.84 APE8-dihe-in -79.09, 72.8 APE8-rot-na 32.94 APE67-dihe-in -75.09, -2.58 -53.56, -42.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.945 T790M,V948R None None XRAY 2.4 0.21 0.239 B 331 285 15 0 0 15 [[712, 970]] 1.0 7jxl Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLC P00533 700 1007 1210.0 VO7:1101 Type1 Inactive DFGin 5.046 14.21 BLBplus -131.44, 169.42 60.64, 42.48 -100.4, 172.86 57.82, 96.69 101.73, -98.55 out-out out 13.295 Saltbr-out 10.82 HRD-in -68.59, -57.74 83.98, -10.65 out-out-out SNCooo out-out ActLoopNT-out 8.773 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 148.84 APE8-dihe-in -84.48, 72.12 APE8-rot-na 33.75 APE67-dihe-in -77.24, -3.14 -52.76, -40.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.068 T790M,V948R None None XRAY 2.4 0.21 0.239 C 331 292 16 0 0 14 [[712, 970]] 1.0 7jxl Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLD P00533 700 1007 1210.0 VO7:1101 Type1 Inactive DFGin 5.173 13.928 BLBplus -133.7, 169.87 61.73, 43.83 -103.39, 170.74 58.35, 94.82 87.82, 34.82 out-out out 13.626 Saltbr-out 11.064 HRD-in -67.75, -57.45 83.8, -10.92 out-out-none SNCoon out-none ActLoopNT-out 9.169 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 68.84 APE8-rot-na 32.75 APE67-dihe-in -76.98, -2.85 -51.41, -42.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 2.4 0.21 0.239 D 331 292 16 0 0 16 [[712, 970]] 1.0 7jxl Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLA P00533 701 1013 1210.0 VO7:1101 Type1 Inactive DFGin 5.542 16.067 BLBtrans -126.4, -179.97 66.03, 31.68 -87.54, 145.45 161.25, 72.83 92.56, -6.61 out-out out 13.282 Saltbr-out 13.233 HRD-in -72.85, -58.8 84.46, -15.1 out-out-none SNCoon out-none ActLoopNT-out 9.348 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 142.61 APE8-dihe-in -82.4, 69.83 APE8-rot-na 33.22 APE67-dihe-in -77.96, -2.7 -53.21, -40.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.765 T790M,V948R None None XRAY 2.4 0.21 0.239 A 331 294 19 0 0 14 [[712, 970]] 1.0 7jxl Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: VO7

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name