Ligand: UKI

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8JMZA
DFGout BBAminus 1 33.3% 8JOTA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR CSF1R CSF1R_HUMAN 8JOTA 1.69 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai UKI Type1 543 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR FGFR1 FGFR1_HUMAN 8JMZA 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 460 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JMZB 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 458 - 763 0 None C584S Fibroblast growth factor receptor 1

Ligand: UKI

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8JMZA
DFGout BBAminus 1 33.3% 8JOTA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR CSF1R CSF1R_HUMAN 8JOTA 1.69 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai UKI Type1 543 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8JMZA 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 460 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8JMZB 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens

Ligand: UKI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism