Ligand: UKI

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8JMZA
DFGout BBAminus 1 33.3% 8JOTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR CSF1R CSF1R_HUMAN 8JOTA P07333 543 914 972.0 UKI:1001 Type1 Inactive DFGout 11.7904 10.1716 BBAminus -152.53, -164.7 -132.78, 111.2 -118.89, 28.73 306.09, 111.3 -53.84, -35.65 in-in in 7.9469 Saltbr-in 2.6766 HRD-in -85.99, -51.0 73.56, 2.04 in-out-in SNCioi out-in ActLoopNT-out 17.5655 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -110.76, 114.95 APE9-dihe-in -118.98, 139.94 APE8-dihe-in -78.88, 70.02 APE8-rot-na 34.05 APE67-dihe-in -68.92, -12.46 -61.18, -37.88 APE12-dist-na 999.0 APE11-dist-na 16.0805 APE10-dist-na 12.7301 APE9-dist-in 7.6394 C667T,C830S,C907T None None XRAY 1.69 0.18 0.207 A 354.0 306.0 26 30 29 1 [[582, 912]] 1.0 8jot TYR_CSF1R_HUMAN TYR 1.2e-104 356.1 1.0 260.0 260.0 795 796 797 799 801 616 633 637 775 777 776 778.0 837 825 820 819 818 817 816 815 814 664 Macrophage colony-stimulating factor 1 receptor
TYR FGFR1 FGFR1_HUMAN 8JMZA P11362 460 765 822.0 UKI:60801 Type1 Inactive DFGin 5.1589 13.2886 BLAplus -113.58, 162.96 62.0, 28.58 -83.36, -13.84 56.58, 89.17 -102.65, 12.75 in-in in 7.8587 Saltbr-in 2.8351 HRD-in -72.3, -51.47 78.17, -4.24 in-out-out SNCioo out-out ActLoopNT-out 7.9805 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -88.22, 148.56 APE9-dihe-in -107.32, 99.52 APE8-dihe-out -56.46, -18.86 APE8-rot-na 328.17 APE67-dihe-in -74.96, -9.03 -56.04, -27.86 APE12-dist-na 16.4248 APE11-dist-na 18.9969 APE10-dist-na 16.2227 APE9-dist-out 11.0211 C584S None None XRAY 1.988 0.166 0.205 A 310.0 306.0 0 30 30 0 [[478, 756]] 1.0 8jmz TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JMZB P11362 458 763 822.0 UKI:60801 Type1 Inactive DFGin 5.259 13.0071 BLAplus -114.88, 158.62 61.68, 33.22 -84.25, -18.02 53.38, 88.43 -92.93, -0.34 in-in in 7.7668 Saltbr-in 2.9243 HRD-in -72.45, -50.78 74.31, -4.23 in-out-out SNCioo out-out ActLoopNT-out 8.3535 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -137.73, 168.34 APE9-dihe-in -103.17, 113.28 APE8-dihe-out -51.14, -25.22 APE8-rot-na 328.21 APE67-dihe-in -74.28, -2.47 -57.8, -24.89 APE12-dist-na 20.439 APE11-dist-na 21.4008 APE10-dist-na 20.0649 APE9-dist-out 11.5011 C584S None None XRAY 1.988 0.166 0.205 B 310.0 290.0 16 30 27 3 [[478, 756]] 1.0 8jmz TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

Ligand: UKI

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 66.7% 8JMZA
DFGout BBAminus 1 33.3% 8JOTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR CSF1R CSF1R_HUMAN 8JOTA P07333 543 914 972.0 UKI:1001 Type1 Inactive DFGout 11.7904 10.1716 BBAminus -152.53, -164.7 -132.78, 111.2 -118.89, 28.73 306.09, 111.3 -53.84, -35.65 in-in in 7.9469 Saltbr-in 2.6766 HRD-in -85.99, -51.0 73.56, 2.04 in-out-in SNCioi out-in ActLoopNT-out 17.5655 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -110.76, 114.95 APE9-dihe-in -118.98, 139.94 APE8-dihe-in -78.88, 70.02 APE8-rot-na 34.05 APE67-dihe-in -68.92, -12.46 -61.18, -37.88 APE12-dist-na 999.0 APE11-dist-na 16.0805 APE10-dist-na 12.7301 APE9-dist-in 7.6394 C667T,C830S,C907T None None XRAY 1.69 0.18 0.207 A 354.0 306.0 26 30 29 1 [[582, 912]] 1.0 8jot Homo sapiens TYR_CSF1R_HUMAN TYR 1.2e-104 356.1 1.0 260.0 260.0 795 796 797 799 801 616 633 637 775 777 776 778.0 837 825 820 819 818 817 816 815 814 664 Macrophage colony-stimulating factor 1 receptor
TYR FGFR1 FGFR1_HUMAN 8JMZA P11362 460 765 822.0 UKI:60801 Type1 Inactive DFGin 5.1589 13.2886 BLAplus -113.58, 162.96 62.0, 28.58 -83.36, -13.84 56.58, 89.17 -102.65, 12.75 in-in in 7.8587 Saltbr-in 2.8351 HRD-in -72.3, -51.47 78.17, -4.24 in-out-out SNCioo out-out ActLoopNT-out 7.9805 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -88.22, 148.56 APE9-dihe-in -107.32, 99.52 APE8-dihe-out -56.46, -18.86 APE8-rot-na 328.17 APE67-dihe-in -74.96, -9.03 -56.04, -27.86 APE12-dist-na 16.4248 APE11-dist-na 18.9969 APE10-dist-na 16.2227 APE9-dist-out 11.0211 C584S None None XRAY 1.988 0.166 0.205 A 310.0 306.0 0 30 30 0 [[478, 756]] 1.0 8jmz Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JMZB P11362 458 763 822.0 UKI:60801 Type1 Inactive DFGin 5.259 13.0071 BLAplus -114.88, 158.62 61.68, 33.22 -84.25, -18.02 53.38, 88.43 -92.93, -0.34 in-in in 7.7668 Saltbr-in 2.9243 HRD-in -72.45, -50.78 74.31, -4.23 in-out-out SNCioo out-out ActLoopNT-out 8.3535 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -137.73, 168.34 APE9-dihe-in -103.17, 113.28 APE8-dihe-out -51.14, -25.22 APE8-rot-na 328.21 APE67-dihe-in -74.28, -2.47 -57.8, -24.89 APE12-dist-na 20.439 APE11-dist-na 21.4008 APE10-dist-na 20.0649 APE9-dist-out 11.5011 C584S None None XRAY 1.988 0.166 0.205 B 310.0 290.0 16 30 27 3 [[478, 756]] 1.0 8jmz Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

Ligand: UKI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name