Ligand: P01

Total number of chains: 4
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 25.0% 2IZUA
DFGin BLBplus 1 25.0% 2Z7SA
DFGin None 1 25.0% 1YOMB
None None 1 25.0% 1YOMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7SA Q15418 56 340 735.0 P01:1 Type1 Inactive DFGin 7.2187 12.6354 BLBplus -132.64, 170.38 54.15, 50.71 -114.94, -156.75 52.84, 81.1 107.65, -49.27 none-none none 999.0 Saltbr-none 999.0 HRD-out -71.6, 70.9 -56.92, -36.92 none-out-out SNCnoo out-out ActLoopNT-out 7.0904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 173.47 APE8-dihe-in -68.64, 105.29 APE8-rot-in 308.32 APE67-dihe-in -56.06, -20.75 -56.93, -41.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 6.7344 None None None XRAY 2.1 0.279 999.0 A 321.0 256.0 29 28 16 12 [[62, 321], [418, 675]] 2.0 2z7s AGC_RPS6KA1-1_HUMAN AGC 1.5e-95 325.1 1.0 260.0 260.0 204 205 206 208 210 94 112 116 184 186 185 187.0 244 232 227 226 225 224 223 222 221 142 Ribosomal protein S6 kinase alpha-1
CK1 CSNK1G3 KC1G3_HUMAN 2IZUA Q9Y6M4 36 334 447.0 P01:1335 Type1 Active DFGin 6.7703 15.1029 BLAminus -126.02, 170.21 68.65, 86.79 -102.43, 21.59 285.32, 82.09 -64.81, -28.14 in-in in 7.826 Saltbr-in 2.7277 HRD-in -90.83, -55.24 68.17, 14.08 in-in-in SNCiii in-in ActLoopNT-in 2.8122 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.52, 134.97 APE9-dihe-na 92.89, -168.35 APE8-dihe-in -90.38, 128.9 APE8-rot-in 304.02 APE67-dihe-in -61.26, -34.46 -55.52, -36.35 APE12-dist-in 11.4317 APE11-dist-in 12.037 APE10-dist-in 6.3729 APE9-dist-in 3.8389 None None None XRAY 1.85 0.157 0.199 A 330.0 297.0 2 35 35 0 [[43, 310]] 1.0 2izu CK1_CSNK1G3_HUMAN CK1 2.4e-115 390.4 1.0 261.0 261.0 184 185 186 188 190 72 86 90 159 161 160 162.0 231 219 214 213 212 211 210 209 208 117 Casein kinase I isoform gamma-3
TYR SRC SRC_HUMAN 1YOMB P12931 258 536 536.0 P01:60002 Type1 Inactive DFGin 7.1447 15.9556 None -150.45, -153.06 39.29, 44.85 -55.46, 999.0 262.87, 79.79 999.0, 999.0 in-none in 7.3529 Saltbr-none 999.0 HRD-in -98.52, -48.38 85.73, -24.58 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.01 APE8-dihe-out -94.51, 44.94 APE8-rot-na 35.15 APE67-dihe-in -62.96, -31.73 -55.8, -34.94 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 9.5153 S345N,A370S,Y419W None None XRAY 2.9 0.222 0.313 B 283.0 261.0 18 29 11 18 [[270, 521]] 1.0 1yom TYR_SRC_HUMAN TYR 1.9e-93 318.4 1.0 260.0 260.0 406 407 408 410 412 298 313 317 386 388 387 389.0 447 435 430 429 428 427 426 425 424 342 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOMA P12931 258 536 536.0 P01:60001 Type1 Inactive None 999.0 999.0 None 158.85, -179.51 -171.63, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 in-none in 8.6713 Saltbr-none 999.0 HRD-in -78.64, -52.38 82.21, -0.58 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.68 APE8-dihe-in -95.25, 68.77 APE8-rot-na 39.27 APE67-dihe-in -66.01, -26.81 -65.26, -36.93 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 9.3178 S345N,A370S,Y419W None None XRAY 2.9 0.222 0.313 A 283.0 260.0 19 29 10 19 [[270, 521]] 1.0 1yom TYR_SRC_HUMAN TYR 1.9e-93 318.4 1.0 260.0 260.0 406 407 408 410 412 298 313 317 386 388 387 389.0 447 435 430 429 428 427 426 425 424 342 Proto-oncogene tyrosine-protein kinase Src

Ligand: P01

Total number of chains: 4
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 25.0% 2IZUA
DFGin BLBplus 1 25.0% 2Z7SA
DFGin None 1 25.0% 1YOMB
None None 1 25.0% 1YOMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7SA Q15418 56 340 735.0 P01:1 Type1 Inactive DFGin 7.2187 12.6354 BLBplus -132.64, 170.38 54.15, 50.71 -114.94, -156.75 52.84, 81.1 107.65, -49.27 none-none none 999.0 Saltbr-none 999.0 HRD-out -71.6, 70.9 -56.92, -36.92 none-out-out SNCnoo out-out ActLoopNT-out 7.0904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 173.47 APE8-dihe-in -68.64, 105.29 APE8-rot-in 308.32 APE67-dihe-in -56.06, -20.75 -56.93, -41.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 6.7344 None None None XRAY 2.1 0.279 999.0 A 321.0 256.0 29 28 16 12 [[62, 321], [418, 675]] 2.0 2z7s Homo sapiens AGC_RPS6KA1-1_HUMAN AGC 1.5e-95 325.1 1.0 260.0 260.0 204 205 206 208 210 94 112 116 184 186 185 187.0 244 232 227 226 225 224 223 222 221 142 Ribosomal protein S6 kinase alpha-1
CK1 CSNK1G3 KC1G3_HUMAN 2IZUA Q9Y6M4 36 334 447.0 P01:1335 Type1 Active DFGin 6.7703 15.1029 BLAminus -126.02, 170.21 68.65, 86.79 -102.43, 21.59 285.32, 82.09 -64.81, -28.14 in-in in 7.826 Saltbr-in 2.7277 HRD-in -90.83, -55.24 68.17, 14.08 in-in-in SNCiii in-in ActLoopNT-in 2.8122 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.52, 134.97 APE9-dihe-na 92.89, -168.35 APE8-dihe-in -90.38, 128.9 APE8-rot-in 304.02 APE67-dihe-in -61.26, -34.46 -55.52, -36.35 APE12-dist-in 11.4317 APE11-dist-in 12.037 APE10-dist-in 6.3729 APE9-dist-in 3.8389 None None None XRAY 1.85 0.157 0.199 A 330.0 297.0 2 35 35 0 [[43, 310]] 1.0 2izu Homo sapiens CK1_CSNK1G3_HUMAN CK1 2.4e-115 390.4 1.0 261.0 261.0 184 185 186 188 190 72 86 90 159 161 160 162.0 231 219 214 213 212 211 210 209 208 117 Casein kinase I isoform gamma-3
TYR SRC SRC_HUMAN 1YOMB P12931 258 536 536.0 P01:60002 Type1 Inactive DFGin 7.1447 15.9556 None -150.45, -153.06 39.29, 44.85 -55.46, 999.0 262.87, 79.79 999.0, 999.0 in-none in 7.3529 Saltbr-none 999.0 HRD-in -98.52, -48.38 85.73, -24.58 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.01 APE8-dihe-out -94.51, 44.94 APE8-rot-na 35.15 APE67-dihe-in -62.96, -31.73 -55.8, -34.94 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 9.5153 S345N,A370S,Y419W None None XRAY 2.9 0.222 0.313 B 283.0 261.0 18 29 11 18 [[270, 521]] 1.0 1yom Homo sapiens TYR_SRC_HUMAN TYR 1.9e-93 318.4 1.0 260.0 260.0 406 407 408 410 412 298 313 317 386 388 387 389.0 447 435 430 429 428 427 426 425 424 342 Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOMA P12931 258 536 536.0 P01:60001 Type1 Inactive None 999.0 999.0 None 158.85, -179.51 -171.63, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 in-none in 8.6713 Saltbr-none 999.0 HRD-in -78.64, -52.38 82.21, -0.58 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.68 APE8-dihe-in -95.25, 68.77 APE8-rot-na 39.27 APE67-dihe-in -66.01, -26.81 -65.26, -36.93 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 9.3178 S345N,A370S,Y419W None None XRAY 2.9 0.222 0.313 A 283.0 260.0 19 29 10 19 [[270, 521]] 1.0 1yom Homo sapiens TYR_SRC_HUMAN TYR 1.9e-93 318.4 1.0 260.0 260.0 406 407 408 410 412 298 313 317 386 388 387 389.0 447 435 430 429 428 427 426 425 424 342 Proto-oncogene tyrosine-protein kinase Src

Ligand: P01

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name