Ligand: O57

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 6P8QC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6P8QA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, O57 ATPlike, Type3 699 - 1019 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QB 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai AMP, O57 ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QC 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai AMP, O57 ATPlike, Type3 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QD 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai AMP, O57 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor

Ligand: O57

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 6P8QC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6P8QA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, O57 ATPlike, Type3 699 - 1019 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P8QB 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai AMP, O57 ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P8QC 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai AMP, O57 ATPlike, Type3 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P8QD 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai AMP, O57 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: O57

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism