Ligand: O57

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 6P8QC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6P8QA P00533 699 1019 1210.0 ANP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.2914 14.4671 BLBplus -136.39, 166.39 65.62, 19.67 -68.64, 141.86 47.45, 96.29 88.91, -15.41 out-out out 13.7934 Saltbr-out 13.3942 HRD-in -77.48, -60.3 86.7, -15.68 out-out-none SNCoon out-none ActLoopNT-out 6.9269 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.69 APE8-dihe-in -82.28, 70.48 APE8-rot-na 31.78 APE67-dihe-in -69.54, -10.7 -59.7, -40.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5228 T790M,V948R None None XRAY 1.9 0.169 0.195 A 327.0 309.0 12 30 18 12 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QB P00533 698 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.2756 14.4668 BLBplus -135.86, 166.31 67.07, 15.83 -64.3, 136.34 50.27, 96.09 85.52, -9.82 out-out out 13.5405 Saltbr-out 13.7005 HRD-in -74.24, -59.24 89.14, -20.92 out-out-none SNCoon out-none ActLoopNT-out 6.9736 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 150.09 APE9-dihe-in -104.23, 113.6 APE8-dihe-in -82.27, 71.52 APE8-rot-na 22.76 APE67-dihe-in -69.35, -13.24 -58.74, -40.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.8768 APE9-dist-in 7.9928 T790M,V948R None None XRAY 1.9 0.169 0.195 B 327.0 300.0 10 30 20 10 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QC P00533 699 1014 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.3091 14.5901 BLBplus -130.27, 166.7 65.36, 18.32 -66.06, 140.33 49.17, 97.15 81.91, -12.21 out-out out 13.8298 Saltbr-out 13.5909 HRD-in -81.24, -59.54 87.32, -15.78 out-out-in SNCooi out-in ActLoopNT-out 6.911 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.57, 147.96 APE9-dihe-in -130.06, 156.46 APE8-dihe-in -83.94, 74.96 APE8-rot-na 27.22 APE67-dihe-in -70.93, -14.87 -56.96, -36.77 APE12-dist-na 16.9274 APE11-dist-na 13.6759 APE10-dist-na 14.094 APE9-dist-in 7.7213 T790M,V948R None None XRAY 1.9 0.169 0.195 C 327.0 316.0 0 30 30 0 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QD P00533 700 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.3675 14.3162 BLBplus -131.89, 166.57 70.0, 15.99 -68.19, 140.48 43.77, 99.15 83.83, -10.13 out-out out 13.4259 Saltbr-out 13.1489 HRD-in -73.29, -58.03 87.0, -17.51 out-out-none SNCoon out-none ActLoopNT-out 6.8943 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 92.37 APE8-dihe-in -76.46, 76.63 APE8-rot-na 30.25 APE67-dihe-in -71.2, -11.99 -56.02, -38.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4485 T790M,V948R None None XRAY 1.9 0.169 0.195 D 327.0 296.0 12 30 18 12 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: O57

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 6P8QC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6P8QA P00533 699 1019 1210.0 ANP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.2914 14.4671 BLBplus -136.39, 166.39 65.62, 19.67 -68.64, 141.86 47.45, 96.29 88.91, -15.41 out-out out 13.7934 Saltbr-out 13.3942 HRD-in -77.48, -60.3 86.7, -15.68 out-out-none SNCoon out-none ActLoopNT-out 6.9269 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.69 APE8-dihe-in -82.28, 70.48 APE8-rot-na 31.78 APE67-dihe-in -69.54, -10.7 -59.7, -40.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5228 T790M,V948R None None XRAY 1.9 0.169 0.195 A 327.0 309.0 12 30 18 12 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QB P00533 698 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.2756 14.4668 BLBplus -135.86, 166.31 67.07, 15.83 -64.3, 136.34 50.27, 96.09 85.52, -9.82 out-out out 13.5405 Saltbr-out 13.7005 HRD-in -74.24, -59.24 89.14, -20.92 out-out-none SNCoon out-none ActLoopNT-out 6.9736 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 150.09 APE9-dihe-in -104.23, 113.6 APE8-dihe-in -82.27, 71.52 APE8-rot-na 22.76 APE67-dihe-in -69.35, -13.24 -58.74, -40.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.8768 APE9-dist-in 7.9928 T790M,V948R None None XRAY 1.9 0.169 0.195 B 327.0 300.0 10 30 20 10 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QC P00533 699 1014 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.3091 14.5901 BLBplus -130.27, 166.7 65.36, 18.32 -66.06, 140.33 49.17, 97.15 81.91, -12.21 out-out out 13.8298 Saltbr-out 13.5909 HRD-in -81.24, -59.54 87.32, -15.78 out-out-in SNCooi out-in ActLoopNT-out 6.911 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.57, 147.96 APE9-dihe-in -130.06, 156.46 APE8-dihe-in -83.94, 74.96 APE8-rot-na 27.22 APE67-dihe-in -70.93, -14.87 -56.96, -36.77 APE12-dist-na 16.9274 APE11-dist-na 13.6759 APE10-dist-na 14.094 APE9-dist-in 7.7213 T790M,V948R None None XRAY 1.9 0.169 0.195 C 327.0 316.0 0 30 30 0 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QD P00533 700 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.3675 14.3162 BLBplus -131.89, 166.57 70.0, 15.99 -68.19, 140.48 43.77, 99.15 83.83, -10.13 out-out out 13.4259 Saltbr-out 13.1489 HRD-in -73.29, -58.03 87.0, -17.51 out-out-none SNCoon out-none ActLoopNT-out 6.8943 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 92.37 APE8-dihe-in -76.46, 76.63 APE8-rot-na 30.25 APE67-dihe-in -71.2, -11.99 -56.02, -38.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4485 T790M,V948R None None XRAY 1.9 0.169 0.195 D 327.0 296.0 12 30 18 12 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: O57

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name