Protein kinases in complex with L20

Total number of genes: 3
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 2 2JDRA
DFGin BLBplus 1 9IRLA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 2JDRA 2.3 Active DFGin BLAminus in-in in-in L20 Type1
CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 5DGZA 2.502 Active DFGin BLAminus in-in in-in L20 Type1
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 9IRLA 2.031 Inactive DFGin BLBplus out-out out-out A1L20 Allosteric

Protein kinases in complex with L20

Total number of genes: 4
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 5 2JDSA
DFGin BLBplus 1 9IRLA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2UZUE 2.4 Active DFGin BLAminus in-in in-in L20 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2JDSA 2.0 Active DFGin BLAminus in-in in-in L20 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2JDVA 2.08 Active DFGin BLAminus in-in in-in L20 Type1
Homo sapiens AGC AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 2JDRA 2.3 Active DFGin BLAminus in-in in-in L20 Type1
Homo sapiens CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 5DGZA 2.502 Active DFGin BLAminus in-in in-in L20 Type1
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 9IRLA 2.031 Inactive DFGin BLBplus out-out out-out A1L20 Allosteric

Protein kinases in complex with L20

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 3 2JDSA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2UZUE 2.4 Active DFGin BLAminus in-in in-in L20 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2JDSA 2.0 Active DFGin BLAminus in-in in-in L20 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2JDVA 2.08 Active DFGin BLAminus in-in in-in L20 Type1